Colada morada, a traditional Ecuadorian Day of the dead beverage: Bibliometric analysis and review of the biological activity of native Ecuadorian ingredients by Juan Carlos Romero-Benavides, Rodrigo Duarte-Casar, Marlene Rojas-Le-Fort, Natalia Bailon-Moscoso

“…Using bibliometric analysis and document reviews, we identified major bioactive compounds such as phenolic acids, anthocyanins, flavonoids, terpenoids, and proteolytic enzymes, which exhibit antioxidant, antimicrobial, anti-inflammatory, and chemopreventive properties. …”
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AGS3-based optogenetic GDI induces GPCR-independent Gβγ signalling and macrophage migration by Waruna Thotamune, Sithurandi Ubeysinghe, Chathuri Rajarathna, Dinesh Kankanamge, Koshala Olupothage, Aditya Chandu, Bryan A. Copits, Ajith Karunarathne

“…GPCRs primarily broadcast signals through activated G proteins, GαGTP and free Gβγ and are major disease drivers. Evidence shows that the ambient low threshold signalling required for cells is likely supplemented by signalling regulators such as non-GPCR GEFs and guanine nucleotide dissociation inhibitors (GDIs). …”
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Visible light induced photocatalytic degradation of norfloxacin using xC-TiO2 by Adnan, Kalsoom, Farah Muhammad Zada, Sarwat, Ho Soonmin, Behramand Khan, Muhammad Alamzeb, Wei Sun, Jawad Ikram, Najeeb ur Rehman

“…In recent years, antibiotic pollution has become a major environmental concern. The extensive production and widespread use of prescribed antibiotics have significantly impacted ecosystems. …”
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Hybrid Graph Representation Learning for Carotid Artery Stenosis Detection Based on Multimodal Retinal OCTA Images by Wenting Lan, Jinkui Hao, Shengjun Zhou, Jingfeng Zhang, Shaodong Ma, Yitian Zhao

“…Carotid artery stenosis (CAS) is one of the major causes of cerebral ischemic stroke. Rapid and precise detection of CAS is crucial for early intervention and reducing ischemic stroke incidence. …”
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Wavenumber-dependent transmission of subthreshold waves on electrical synapses network model of Caenorhabditis elegans by Iksoo Chang, Taegon Chung, Sangyeol Kim

“…Also, we unraveled that (1) the transmission of all cell-pairs disappeared beyond a threshold wavenumber, (2) long distance and regular patterned transmission existed in the body-wall muscles part of the model network, and (3) major hub cell-pairs of the transmission were identified for many wavenumber conditions. …”
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Oscillatory response of Larsen C Ice Shelf flow to the calving of iceberg A-68 by Katherine A. Deakin, Frazer D. W. Christie, Karla Boxall, Ian C. Willis

“…While falling close to the limits of detectability, these ice-flow variations appear to have been presaged by similar oscillations in the years prior to A-68's breakaway, associated primarily with major rifting events, together reflecting potentially hitherto unobserved ice-shelf mechanical processes with important implications for ice-shelf weakening. …”
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Optimal Network Reconfiguration and Scheduling With Hardware-in-the-Loop Validation for Improved Microgrid Resilience by Yang Chen, Mohammed Olama, Maximiliano F. Ferrari, Guodong Liu, Qingxin Shi, Aditya Sundararajan, Byungkwon Park, Arturo A. Massol-Deya, Thomas B. Ollis

“…With the increased occurrence of various major extreme weather events, power outages and prompt power system restorations have recently drawn more attention to the resilience and recovery of power systems. …”
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Detecting the Early Stage of Phaeosphaeria Leaf Spot Infestations in Maize Crop Using In Situ Hyperspectral Data and Guided Regularized Random Forest Algorithm by Elhadi Adam, Houtao Deng, John Odindi, Elfatih M. Abdel-Rahman, Onisimo Mutanga

“…Phaeosphaeria leaf spot (PLS) is considered one of the major diseases that threaten the stability of maize production in tropical and subtropical African regions. …”
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Spatio-temporal analysis of litterfall load in the lower reaches of Qarqan and Tarim rivers using BP neural networks by Junyu Xu, Anwar Eziz, Alishir Kurban, Ümüt Halik, Zhiwen Shi, Saif Ullah, Gift Donu Fidelis, Yingdong Ma, Ziwargul Kibir, Toqeer Ahmed, Tim Van de Voorde, Adil Hujashim, Hossein Azadi

“…This study aims to estimate Litterfall load using a BP neural network based on vegetation indices from Landsat 5 and 8 satellite images, litterfall inventory data, slope, and distance to major river tributaries. It also aims to analyze the spatiotemporal distribution pattern of litter in the research area by estimating and analyzing the spatiotemporal pattern of litterfall along the desert riparian forests of the lower Qarqan and Tarim Rivers from 2001 to 2021. …”
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Reforming public service of Republic of Kazakhstan as necessary condition for effective development of national economy by S. S. Dontsov, A. S. Kadyrova, S. A. Rakhimova, A. A. Nurgaliyeva, A. A. Titkov

“…The article emphasizes the importance of rational reforms of the public service in Kazakhstan for the successful implementation of all major strategic plans and effective development of the national economy as a whole. …”
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The role of milk urea nitrogen in nutritional assessment and its relationship with phenotype of dairy cows: A review by Xiaowei Zhao, Nan Zheng, Yangdong Zhang, Jiaqi Wang

“…Many studies have suggested that intake of dietary protein and energy, as well as their synchronized release in the rumen, are major factors influencing MUN concentration. Therefore, measuring MUN can serve as a valuable indicator for improving nutritional management in dairy herds. …”
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Personalized medicine: An alternative for cancer treatment by Devendra Singh, Vinay Kumar Dhiman, Minakshi Pandey, Vivek Kumar Dhiman, Avinash Sharma, Himanshu Pandey, Sunil Kumar Verma, Rajeev Pandey

“…In recent years, personalized medicine has achieved major advances in the treatment of solid tumors, with the promise to improve treatment precision, reduce side effects, as well as enhance outcomes for patients in cancer therapy. …”
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A comparative study on spin-to-charge and charge-to-spin conversion using modulated Dirac surface states of Bi2Se3 by Youngmin Lee, Jonghoon Kim, Seungwon Rho, Seok-Bo Hong, Hyeongmun Kim, Jaehan Park, Dajung Kim, Chul Kang, Myung-Ho Bae, Mann-Ho Cho

“…Understanding the mechanisms of spin-charge interconversion is a major challenge in modern spintronics. In this study, we investigate the complex charge-to-spin conversion (CSC) and spin-to-charge conversion (SCC) using the modulated Dirac surface state of Bi2Se3 thin films. …”
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Association between atherogenic index of plasma and type 2 diabetic complications: a cross-sectional study by Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Xiao-Yu Yang, Xiao-Yu Yang, Xiao-Yu Yang, Xiao-Yu Yang, Xiao-Yu Yang, Qin Wan, Qin Wan, Qin Wan, Qin Wan, Qin Wan

“…In this study, logistic regression, restricted cubic splines, and subgroup analyses were employed to evaluate the association between the AIP and four major complications of type 2 diabetes, namely, type 2 diabetes with carotid atherosclerosis (DA), diabetic kidney disease (DKD), diabetic retinopathy (DR), and diabetic peripheral neuropathy (DPN).ResultsThe logistic regression results demonstrate that in the fully adjusted model, each SD increase in AIP correlates with an elevated risk of type 2 diabetic kidney disease (DKD), with the risk of kidney damage intensifying alongside higher AIP groupings. …”
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Toxicological landscape of Fuzi: a comprehensive study on the spatial distribution of toxicants and regional neurotoxicity variability in zebrafish by Xiaoqi Pan, Xiaoqi Pan, Tianyu Liang, Han Feng, Weiying Liu, Qiaoxin Mou, Xiaoyu Yan

“…Matrix-assisted laser desorption/Ionization mass spectrometry imaging (MALDI-MSI) method was employed to map the spatial distribution of six key diester-type alkaloids from Fuzi samples originating from five major regions. The results showed that the diester-type alkaloids were primarily distributed in the cuticle of Anguo- and Ludian-Fuzi, in the cuticle, cork, and pith of Butuo-Fuzi, in the phloem and pith tissues of Chenggu-Fuzi, and in the cuticle, cork, inner phloem, and pith of Jiangyou-Fuzi. …”
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Patterns of Cell Activity in the Subthalamic Region Associated with the Neuroprotective Action of Near-Infrared Light Treatment in MPTP-Treated Mice by Victoria E. Shaw, Cassandra Peoples, Sharon Spana, Keyoumars Ashkan, Alim-Louis Benabid, Jonathan Stone, Gary E. Baker, John Mitrofanis

“…Brains were processed for Fos immunochemistry, and cell number was estimated using stereology. Our major finding was that NIr treatment reduced (30–45%) the increase in Fos+ cell number evident in the STN and ZI after MPTP insult. …”
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A Survey of Data Partitioning and Sampling Methods to Support Big Data Analysis by Mohammad Sultan Mahmud, Joshua Zhexue Huang, Salman Salloum, Tamer Z. Emara, Kuanishbay Sadatdiynov

“…Computer clusters with the shared-nothing architecture are the major computing platforms for big data processing and analysis. …”
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Lymphoid Progenitor Cells from Childhood Acute Lymphoblastic Leukemia Are Functionally Deficient and Express High Levels of the Transcriptional Repressor Gfi-1 by Jessica Purizaca, Adriana Contreras-Quiroz, Elisa Dorantes-Acosta, Eduardo Vadillo, Lourdes Arriaga-Pizano, Silvestre Fuentes-Figueroa, Horacio Villagomez-Barragán, Patricia Flores-Guzmán, Antonio Alvarado-Moreno, Hector Mayani, Isaura Meza, Rosaura Hernandez, Sara Huerta-Yepez, Rosana Pelayo

“…Together, our findings reveal major functional defects in the primitive hematopoietic component of ALL BM. …”
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Tick species, tick-borne pathogen distribution and risk factor analysis in border areas of China, Russia and North Korea by Pengfei Min, Jianchen Song, Shaowei Zhao, Zhen Ma, Yinbiao Meng, Zeyu Tang, Zhenyu Wang, Sicheng Lin, Fanglin Zhao, Meng Liu, Longsheng Wang, Lijun Jia, Lijun Jia

“…Ticks and tick-borne diseases (TBDs) cause losses to the animal husbandry industry and also present a major hidden danger to public health and safety. …”
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Parametrization of the dying brain: A case report from ICU bed-side EEG monitoring by Sebastian Zinn, Srdjan Z. Dragovic, Jan A. Kloka, Laurent M. Willems, Sebastian Harder, Stephan Kratzer, Kai D. Zacharowski, Gerhard Schneider, Paul S. García, Matthias Kreuzer

“…Methods: We report neurophysiologic features of a dying patient without major cortical injury. Sixty minutes of frontal EEG activity was recorded using the Sedline™ monitor. …”
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