Numerical Simulation and Sensitivity Analysis of Hydraulic Fracturing in Multilayered Thin Tight Sandstone Gas Reservoir by Hao Zhang, Yuhu Bai, Bingxiang Xu, Xulin Du, Shaohua Gai

“…Relying on a real reservoir in the Ordos Basin in China, relevant geological and geomechanical parameters of major gas layers and interlayers are obtained. According to these parameters, the hydraulic fracturing simulation in the multilayered thin tight gas reservoir model is carried out, based on which, the sensitivity analysis of different geological and fracturing parameters which affect the fracture propagation is performed. …”
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Oral Finasteride (5 mg and 2 mg) versus Topical Minoxidil 5% in Female Pattern Hair Loss by Eman Hamed El Morsy, Asmaa Saad Abd Toto, Eman Mohamed Hassan

“…Lacks of consensus for its treatment as well as inconsistent response to treatment modalities are considered major challenges for physicians. Objectives: To assess the safety and efficacy of oral finasteride 5 mg and 2 mg versus topical minoxidil 5% in FPHL both clinically and by trichoscopy. …”
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Seismic Responses and Damage Mechanisms of Deep-Buried Underground Powerhouse in Layered Rock Mass by Meng Zhao, Ming Xiao, Juntao Chen, Hancheng Jin

“…The seismic damage area of lining structure is mainly distributed in the place where the soft rock strata pass through and the upper structure with larger free surface. Additionally, two major damage modes of underground powerhouses in layered rock mass, namely, damage due to structural deformation and interlaminar dislocation, are derived from the numerical results and can be reasonably explained by the corresponding damage mechanisms.…”
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Impact of pollution on microbiological dynamics in the pistil stigmas of Orobanche lutea flowers (Orobanchaceae) by Karolina Wiśniewska, Sebastian Wojciech Przemieniecki, Krzysztof Krawczyk, Anna Hoffmann, Renata Piwowarczyk

“…The predominant colonizers of the pistil stigmas were Proteobacteria (99.25%), with Enterobacteriaceae (49.88%) and Pseudomonadaceae (48.28%) being the major families. The prevalent fungal phylum was Basidiomycota (71.64%), with Filobasidiales (33.14%) and Tremellales (27.27%) as dominant orders. …”
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Mechanism of Nerve Regeneration after Ischemic Stroke Induced by Exercise Intervention by TENG Lili, ZHANG Mei, SONG Wenjing, ZHU Luwen

“…It is a challenge in the prevention and treatment of cerebrovascular diseases, and it is also a major global health concern. Following the IS, in order to cope with the loss of input from neurons in the infarction area induced by ischemia and hypoxia stimulation, the body will spontaneously start the self-repair mechanism and reorganize the neuronal functional connections and neural pathways in the brain. …”
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Preenrichment with Adipose Tissue-Derived Stem Cells Improves Fat Graft Retention in Patients with Contour Deformities of the Face by Muhammad M. Bashir, Muhammad Sohail, Fridoon J. Ahmad, Mahmood S. Choudhery

“…The current preenrichment strategy is noninvasive, safe and can be applied to other diseases that require major tissue augmentation such as breast surgery. …”
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Direct imaging of exoplanets: Legacy and prospects by Chauvin, Gael

“…Understanding how giant and terrestrial planets form and evolve, what is their internal structure and that of their atmosphere, represents one of the major challenges of modern astronomy, which is directly connected to the ultimate search for life at the horizon 2030–2050. …”
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ISSUES AND CHALLENGES OF INTEGRATING TOURISM INTO REGIONAL DEVELOPMENT PLANS by Alexandra-Carmen HODISAN, Alina BADULESCU, Elena HERTE

“…Tourism being one of the major social and economic phenomena of modern times, it is not surprising that, in theory or practice, tourism is considered as an effective tool for development. …”
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Examining spatiotemporal dynamics of CO2 emission at multiscale based on nighttime light data by Binbin Zhang, Zongzheng Liang, Wenru Guo, Zhanyou Cui, Deguang Li

“…The trend value method is utilized to analyze the changing trend of CO2 emission at multiscale levels, covering the Chinese mainland, three major economic regions, and six largest agglomerations from 2012 to 2019. …”
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Defensive responses of most antioxidant genes in the freshwater dinoflagellate Palatinus apiculatus to cadmium stress and their implications by Quynh Thi Nhu Bui, Taehee Kim, Han-Sol Kim, Jang-Seu Ki

“…Photosynthetic dinoflagellates are one of the major microalgal taxa, playing essential roles in biogeochemical cycles and food webs in aquatic environments. …”
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SAFETY OF BRONCHOALVEOLAR LAVAGE IN HEMATOLOGICAL PATIENTS WITH THROMBOCYTOPENIA – A RETROSPECTIVE COHORT STUDY by Ivan GUR, Roei Tounek, Yaniv Dotan, Elite Vainer Evgrafov, Stav Rakedzon, Eyal Fuchs

“…Primary outcomes included major bleeding halting the BAL or deemed significant by the treating physician, need for any respiratory support other than low flow O2 or death within 24 hours. …”
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Erwinia phage Asesino is a nucleus-forming phage that lacks PhuZ by Amy Prichard, Annika Sy, Justin Meyer, Elizabeth Villa, Joe Pogliano

“…All identified nucleus-forming phages fall within the Chimalliviridae family and share a core genome of 68 unique genes including chimallin, the major nuclear shell protein. A well-studied but non-essential protein encoded by many nucleus-forming phages is PhuZ, a tubulin homolog which aids in capsid migration, nucleus rotation, and nucleus positioning. …”
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Acceptability of Children Road Safety Education in Pakistan: A Mixed-Method Approach to Exploring Parents’ and Teachers’ Perspectives by Imran Nawaz, Ariane Cuenen, Geert Wets, Davy Janssens

“…., primary, secondary, and high school), with not even half of the teachers reporting dedicated RSE programs in their curriculum, majorly in secondary and high schools. Both parents and teachers express dissatisfaction with current RSE effectiveness, highlighting a critical need for improvement. …”
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A Postcolonial Conversational Approach to Preaching in Multicultural Contexts by Scott Donahue-Martens

“…The article discusses Homi Bhabha’s <i>The Location of Culture</i> as the second major movement. His notions of hybridity and the distinction between diversity and difference are particularly helpful for pushing against colonial limits. …”
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Global Variations in the Time Delays Between Polar Ionospheric Heating and the Neutral Density Response by Daniel R. Weimer, Piyush M. Mehta, R. J. Licata, W. K. Tobiska

“…Measurements of the neutral density from the Challenging Mini‐satellite Payload (CHAMP) and Gravity Recovery and Climate Experiment (GRACE) missions are used, along with calculations of the total Poynting flux entering the poles. During two major geomagnetic storms in 2003, these data show increased densities are first seen on the dayside edge of the auroral ovals after a surge in the energy input. …”
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The return of raptors to Scotland's skies: Investigating the diets of reintroduced red kites and white-tailed eagles using stable isotopes. by Juliette Waterman, Stuart Black, Naomi Sykes, Andrew C Kitchener, William F Mills, Mark D E Fellowes

“…Reintroductions of red kites Milvus milvus and white-tailed eagles Halieaeetus albicilla to Britain, which were extirpated in the late 19th and early 20th centuries, represent major conservation successes. Here, we measured stable isotope ratios of carbon (δ13C) and nitrogen (δ15N) in feather keratin and bone collagen of museum specimens of red kites and white-tailed eagles, which were collected from across Scotland between the 1800s and 2010s. …”
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Evaluation of Prediction Performances of Deep Learning Models for the Aerodynamic Characteristics of Flettner Rotors by Seo Janghoon, Park Jung Yoon, Ma Juhwan, Kim Young Bu, Park Dong-Woo

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Assessment of the Prevalence and Patterns of Violence against Healthcare Workers in Nigeria: A Multicentre Study by Alphonsus Rukevwe Isara, Zara William Wudiri, Hadiza Abigail Agbo, Luret Albert Lar, Adesuwa Queen Aigbokhaode, Nyemike Simeon Awunor, For Association of Public Health Physicians of Nigeria

“…Verbal abuse, threats, bullying and harassment were the predominant forms of psychological violence. The major consequences of violent attacks on the HCWs were lack of job satisfaction, loss of confidence, low self-esteem, decreased productivity and post-traumatic stress disorder. …”
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Social connectedness as a determinant of mental health: A scoping review. by Priya J Wickramaratne, Tenzin Yangchen, Lauren Lepow, Braja G Patra, Benjamin Glicksburg, Ardesheer Talati, Prakash Adekkanattu, Euijung Ryu, Joanna M Biernacka, Alexander Charney, J John Mann, Jyotishman Pathak, Mark Olfson, Myrna M Weissman

“…Among 8 of 9 studies that focused on loneliness, feeling lonely at baseline was related to adverse outcomes at follow-up including higher risks of major depressive disorder, depressive symptom severity, generalized anxiety disorder, and lower levels of physical activity. …”
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Estrogen receptor beta (ERß) In gastric cancer – A systematic review and meta-analysis by S. Peri, Y. Niv

“…Introduction: Gastric cancer represents a major public health challenge worldwide due to its significant morbidity and mortality rates. …”
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