Prediction of the Binding to the Nuclear Factor NF-Kappa-B by Constituents from <i>Teucrium polium</i> L. Essential Oil by Renilson Castro de Barros, Renato Araújo da Costa, Nesrine Guenane, Boulanouar Bakchiche, Farouk Benaceur, Omer Elkiran, Suelem Daniella Pinho Farias, Vanessa Regina Silva Mota, Maria Fani Dolabela

“…The present study evaluates the components of <i>T. polium</i> essential oil cultivated in the Algerian Saharan Atlas. GC-MS identified the major components as fenchone (31.25%), 3-carene (15.77%), cis-limonene oxide (9.77%), and myrcene (9.15%). …”
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A Case of Left Retroexternal Iliac Artery Megaureter Associated with Additional Renal and Vascular Congenital Anomalies by Amin A. Karadaghy, Matthew T. Bell, Daniel T. Daly, Yun Tan

“…A markedly dilated left extrarenal pelvis (ERP) with a diameter of 3.15 cm was noticed. Three major calyces were found outside of the normal-sized left kidney. …”
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Functional Role of SIL1 in Neurodevelopment and Learning by Shilian Xu, Jia Zhu, Kai Mi, Yan Shen, Xiaomin Zhang

“…Mental retardation is a major symptom of MSS which suggests a role of SIL1 in the development of the central nervous system, but how SIL1 functions remains unclear. …”
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Prospects for the use of <i>Bacillus anthracis</i> toxin in cancer therapy by A. P. Rodionov, S. V. Ivanova, E. A. Artemeva, L. A. Melnikova

“…Cancer is one of the major causes of death in pet animals and humans worldwide. …”
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Health Concerns as the Fundamental Dietary Choices for Potential Stunting Preventions: a Qualitative Study by Inne Soesanti, Taufiqurrahman Taufiqurrahman, Ani Intiyati, Sri Hidayati

“…It is a village bordered on the north by the Java Sea which is abundant of fish majorly consumed by adults. Whereas, children under two years old are scarcely served with fish in their diets.  …”
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The potential impacts of climate and forest changes on streamflow for micro-, meso- and macro-scale catchments in Norway by Shaochun Huang, Stephanie Eisner, Wai Kwok Wong, Nicolas Cattaneo

“…The combined effects of climate and forest development lead to median changes in annual streamflow ranging from −2 % to 8 %. Climate is the major driver of streamflow changes, and forest growth slightly offsets the increase in streamflow caused by climate and reduces runoff generation locally. …”
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Dietary polyphenols reduced the allergenicity of β-lactoglobulin via non-covalent interactions: a study on the structure-allergenicity relationship by Chi Zhang, Qiaozhi Zhang, Huatao Li, Zhouzhou Cheng, Shiyu Fan, Hujun Xie, Zhongshan Gao, Yan Zhang, Linglin Fu

“…In this study, polyphenols from eight botanical sources were extracted to prepare non-covalent complexes with β-lactoglobulin (β-LG), a major allergen in milk. The dominant phenolic compounds bound to β-LG with a diminished allergenicity were identified to investigate their respective role on the structural and allergenic properties of β-LG. …”
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A FSTCN-Based Leak Detection Method for Large-Scale Pipeline Transportation Systems by Du Zhang, Chang-Su Kim, Chul-Hyun Hwang, Tae-Jun Lee, Hoe-Kyung Jung

“…As one of the five major transportation systems, pipeline plays an important role in the energy transportation systems. …”
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Description of the root anatomy of the primary molars using high resolution computed microtomography (Micro-CT). An analysis of three-dimensional root canal system by Benedetta Vidi, Benedetta Vidi, Ana María Gil-Valcarcel, Ana María Gil-Valcarcel, Cristina Obispo-Diaz, Isabel Sanchez-Jorge, Jesús Mena-Álvarez, Juan Manuel Aragoneses-Lamas, Cristina Rico-Romano

“…The mesio-lingual canal has the major mean in mesio-distal and bucco-lingual diameter at coronal third. …”
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Dark diversity and habitat conservation status: Two sides of the same coin for conservation and restoration? by Simon Chollet, Mathilde Dano, Gabrielle Thiébaut, Vincent Jung

“…Our study focuses on two habitats, heathlands and grasslands, both of which present major conservation and restoration challenges. We carried out vegetation surveys in 290 heathlands and 425 grasslands spread throughout the region. …”
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Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadru... by Steven J. Smith, Xue Zhi Zhao, Stephen H. Hughes, Terrence R. Burke

“…The emergence of resistance to second-generation INSTIs has been infrequent and has not yet been a major issue in high-income countries. However, the delayed rollouts of these INSTIs in low- to middle-income countries during the COVID-19 pandemic combined with increased transmission of drug-resistant mutants worldwide are leading to an increase in INSTI resistance. …”
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Effect of metformin on the clinical outcomes of stroke in patients with diabetes: a systematic review and meta-analysis by Jianming Zhu, Jun Wen, Zhihua Huang, Jianyi Liu, Fuqun Luo, Yizhi Guo, Yandeng Li

“…Objectives Stroke is a major cause of death and disability globally, especially among diabetic patients. …”
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Robust Wireless Power Transfer for EVs by Self-Oscillating Controlled Inverters and Identical Single-Coil Transmitting and Receiving Pads by Alireza Eikani, Mohammad Amirkhani, Ehsan Farmahini Farahani, Volker Pickert, Mojtaba Mirsalim, Sadegh Vaez-Zadeh

“…Inductive wireless power transfer (IWPT) with stable output power and high efficiency is a major challenge for charging electric vehicles (EVs). …”
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Progenitor Diversity in the Accreted Stellar Halos of Milky Way–like Galaxies by Sy-Yun Pu, Andrew P. Cooper, Robert J. J. Grand, Facundo A. Gómez, Antonela Monachesi

“…Ongoing large stellar spectroscopic surveys of the Milky Way seek to reconstruct the major events in the assembly history of the Galaxy. …”
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Impact of the COVID-19 pandemic on young people living with HIV in Lesotho: a qualitative study by Christian Mallen, Michelle E Robinson, Thomas Shepherd, Maema Ramaema, Moraoetsi Rakuoane, Ntoli Moletsane, Rafiloe Mpholo, Graham Leigh

“…Analysis consisted of a thematic analysis using principles of constant comparison to explore key and emerging themes.Results Analysis revealed five major themes: ‘financial instability and food insecurity’, ‘challenges to health and well-being’, ‘changing relationship dynamics’, ‘loss of educational opportunities’ and ‘understanding the threat of COVID-19’.Conclusions While participants discussed being able to access antiretroviral therapy, this study highlights the significant impact of the COVID-19 pandemic and associated lockdown measures on the mental health and well-being, financial stability and educational development of young people living with HIV in Lesotho.…”
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Statistical Distribution of Urban Area Reveals a Converging Trend of Global Urban Land Expansion by Shengjie Hu, Zhenlei Yang, Sergio Andres Galindo Torres, Zipeng Wang, Haoying Han, Yoshihide Wada, Thomas Cherico Wanger, Ling Li

“…Abstract Urban land expansion is a major driver of many environmental and societal changes that challenge human well‐being and sustainable development, but its evolutionary process and dynamics are neither clear nor well‐integrated into urban science quantitatively. …”
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Tokay gecko tail regeneration involves temporally collinear expression of HOXC genes and early expression of satellite cell markers by Luthfi Nurhidayat, Vladimir Benes, Sira Blom, Inês Gomes, Nisrina Firdausi, Merijn A. G. de Bakker, Herman P. Spaink, Michael K. Richardson

“…Posterior HOXC genes were activated in a temporally collinear sequence in the regenerating tail. The major precursor populations were stromal cells (regenerating tail) vs. pluripotent stem cells (embryonic tail). …”
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Characterization of the volatile compounds in tea (Camellia sinensis L.) flowers during blooming by Xiangyang Guo, Xiangyang Guo, Xiangyang Guo, Lulu Wang, Xiuting Huang, Qiying Zhou, Qiying Zhou

“…Acetoin and cosmene were first identified in TF-S1 and TF-S2, respectively. The major ACI components differed, with linalool being prominent exhibiting ACI above 27 in all samples. …”
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Active Pedicle Epithelial Flap Transposition Combined with Amniotic Membrane Transplantation for Treatment of Nonhealing Corneal Ulcers by Ting Zhang, Yuexin Wang, Yanni Jia, Dongle Liu, Suxia Li, Weiyun Shi, Hua Gao

“…None of the patients developed major complications. Conclusion. Active pedicle epithelial flap transposition combined with AMT is a simple and effective treatment for nonhealing corneal ulcers.…”
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Application of a novel extracorporeal membrane oxygenation system in awake Hu sheep under various durations by Shuo Ding, Juan Chen, Yanchao Wu, Huiru Lin, Qiqiang Liang, Gaoqin Teng, Zhenjie Liu, Man Huang

“…Anatomical observations and pathological histology analyses of major organs revealed no apparent abnormalities. …”
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