Investigating proteogenomic divergence in patient-derived xenograft models of ovarian cancer by Jesenia M. Perez, Jolene M. Duda, Joohyun Ryu, Mihir Shetty, Subina Mehta, Pratik D. Jagtap, Andrew C. Nelson, Boris Winterhoff, Timothy J. Griffin, Timothy K. Starr, Stefani N. Thomas

“…Analysis of differentially abundant proteins revealed enrichment of distinct biological pathways with major downregulated processes including extracellular matrix organization and the immune system. …”
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Epidemiology Characteristics of Constipation for General Population, Pediatric Population, and Elderly Population in China by Huikuan Chu, Likun Zhong, Hai Li, Xiujing Zhang, Jingzhi Zhang, Xiaohua Hou

“…The factors including female gender, diagnostic criteria, geographical area, age, educational class, and race seemed to have major effects on prevalence of constipation.…”
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Identification and Characterization of TEX101 in Bovine Epididymal Spermatozoa by Subir K. Nagdas, Eric L. McLean, Leeá P. Richardson, Samir Raychoudhury

“…Lectin blots of caput and cauda sperm PM revealed a 38 kDa polypeptide exhibiting the highest affinity to RCA among the several major RCA binding polypeptides. The 38 kDa RCA binding polypeptide of cauda sperm PM was purified and exhibited a charge train of three distinct spots with isoelectric points (pH 5.3 and 5.8). …”
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Excellent energy storage performances for BaTiO3-based multilayer capacitors through synergistic high-entropy and superparaelectric-relaxor strategy by Dong Liu, Long Wang, Xinyi Wang, Ting Tang, Qi Wang, Jin-Rui Li, Bo-Ping Zhang, Li-Feng Zhu

“…However, poor energy-storage density (Urec) and low efficiency (η) resulted from the large remanent polarization (Pr) and low breakdown strength (BDS), have been the major challenge for the application of dielectric capacitors. …”
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Heavy metals concentrations in commercial organic fertilizers and the potential risk of fertilization into soils by Kunjie Su, Qingliang Zhang, Anjing Chen, Xiaoqin Wang, Lingling Zhan, Qiang Rao, Jinxia Wang, Hongjun Yang

“…Abstract Inductively coupled plasma mass spectrometry (ICP-MS) was used to detect heavy metals in 74 typical and representative commercial organic fertilizers (COFs) collected in major COF production areas in China. The potential risk of fertilization into soils was evaluated. …”
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A Joint Technology Combining the Advantages of Capillary Microsampling with Mass Spectrometry Applied to the Trans-Resveratrol Pharmacokinetic Study in Mice by Ying Xu, Song-xia Zhang, Jing Guo, Li-jie Chen, Yu-ligh Liou, Tai Rao, Jing-bo Peng, Ying Guo, Wei-hua Huang, Zhi-rong Tan, Dong-sheng Ou-yang, Hong-hao Zhou, Wei Zhang, Yao Chen

“…It has overcome some of the major limitations revealed in previous pharmacokinetic studies in mice and therefore provides a more effective option for future studies.…”
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MicroRNA-22 Promotes Renal Tubulointerstitial Fibrosis by Targeting PTEN and Suppressing Autophagy in Diabetic Nephropathy by Yingying Zhang, Siqi Zhao, Depei Wu, Xingmei Liu, Mingjun Shi, Yuanyuan Wang, Fan Zhang, Jing Ding, Ying Xiao, Bing Guo

“…Renal tubulointerstitial fibrosis (TIF) is a major feature of diabetic nephropathy (DN). There is increasing evidence demonstrating that microRNAs act as key players in the regulation of autophagy and are involved in DN. …”
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Research trends of neoadjuvant therapy for breast cancer: A bibliometric analysis by Laiping Xie, Yuhang Wang, Andi Wan, Lin Huang, Qing Wang, Wanyan Tang, Xiaowei Qi, Xiaofei Hu

“…The study also highlights the contributions of influential authors like Sibylle Loibl and Gunter von Minckwitz, as well as major journals such as the Journal of Clinical Oncology. …”
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Molecular Epidemiology of Enteric Adenovirus Gastroenteritis in under-Five-Year-Old Children in Iran by Anahita Sanaei Dashti, Pedram Ghahremani, Tayebeh Hashempoor, Abdollah Karimi

“…Acute gastroenteritis is one of the major sources of morbidity and mortality among young children in developed and developing countries. …”
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Antibiogram for Haemodialysis Catheter-Related Bloodstream Infections by Abdul Halim Abdul Gafor, Pau Cheong Ping, Anis Farahanum Zainal Abidin, Muhammad Zulhilmie Saruddin, Ng Kah Yan, Siti Qania’ah Adam, Ramliza Ramli, Anita Sulong, Petrick Periyasamy

“…Haemodialysis (HD) catheter-related bloodstream infections (CRBSIs) are a major complication of long-term catheter use in HD. …”
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An Estimation Model on Electricity Consumption of New Metro Stations by Zhao Yu, Yun Bai, Qian Fu, Yao Chen, Baohua Mao

“…The model considers some major factors influencing the electricity consumption of metro station in terms of both the interior design scheme of a station (e.g., layout of the station and allocation of facilities) and external factors (e.g., passenger volume, air temperature and relative humidity). …”
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Machine Learning Model for Gas–Liquid Interface Reconstruction in CFD Numerical Simulations by Tamon Nakano, Michele Alessandro Bucci, Jean-Marc Gratien, Thibault Faney

“…However, this interface reconstruction step is a major bottleneck of the VoF method due to its high computational cost and low accuracy on unstructured grids. …”
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Knowledge and Attitudes About Emergency Contraception Among Married Women in the Eastern Black Sea Region of Turkey by Yeşim Bayoğlu Tekin, Ülkü Mete Ural, Işık Üstüner, Gülşah Balık, Figen Kır Şahin, Emine Seda Güvendağ Güven

“…CONCLUSIONS: Awareness and knowledge of EC was low among the women interviewed. The major barriers to use of EC are lack of information and misconceptions about EC. …”
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Intelligence Based Controlling Models for Effective Power Tracking and Voltage Enhancement in Grid-PV Systems by I. E. S. Naidu, T. Padmavathi, S. Venkata Padmavathi, Budidi U. Kumar

“…Optimization in extracting energy from the solar panel at different climatic conditions, voltage gain with minimum losses, and enhancing overall system efficiency and power quality are major tasks to be undertaken. The proposed control architecture presents a new Fractional Order Proportional-Integral-Derivative Control (FOPTC) technique and its adaptation mechanism for correct MPPT under dynamic variations of meteorological conditions. …”
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The Effect of Information Level and Coping Style on Pain and Anxiety in Needle Liver Biopsy by Nir Hilzenrat, Rose Yesovitch, Ian Shrier, Maria Stavrakis, Marc Deschênes

“…Sedative drugs are not used because the associated drop in blood pressure mimics hemorrhage, a major complication of the procedure. Cognitive and behavioural techniques have been used to decrease stress in patients undergoing other medical procedures. …”
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Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa by I Rukasha, S T S Pheeha, M R Lekalakala, P Malope

“… Background. COVID-19 has been a major public health concern globally, leading to a higher mortality rate, especially among immunosuppressed individuals, who include pregnant women, people with HIV and people living with other comorbidities. …”
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The System of Civil Rites in the Anti-Religious Policy of the Soviet Government of the 1920s in the North-West of the RSFSR by Tabachnik, Ksenia K.

“…Based on materials from archival documents, pamphlets by Soviet propagandists and major figures of the Bolshevik Party, periodical sources from the funds of the State Museum of the History of Religion, photographic documents, the author attempts to prove the actual borrowing of Christian attributes and their transformation in a revolutionary way. …”
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Multi-decadal evolution of Crary Ice Rise region, West Antarctica, amid modern ice-stream deceleration by Hannah Verboncoeur, Matthew Ross Siegfried, Nicholas Holschuh, Jeremy Paul Winberry, Duncan Byrne, Wilson Sauthoff, Tyler Clark Sutterley, Brooke Medley

“…Here, we construct and analyze a 20-year multi-mission satellite altimetry record of dynamic ice surface-elevation change (dh/dt) in the grounded region encompassing lower Whillans Ice Stream and Crary Ice Rise, a major pinning point of Ross Ice Shelf. We developed a new method for generating multi-mission time series that reduces spatial bias and implemented this method with altimetry data from the Ice, Cloud, and land Elevation Satellite (ICESat; 2003–09), CryoSat-2 (2010–present), and ICESat-2 (2018–present) altimetry missions. …”
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MINERAL FORMS OF TUNGSTEN AT THE POROKHOVSKOE AND YUGO-KONEVSKOE DEPOSITS (SOUTH URALS) by D.A. Rogov, E.V. Belogub, K.A. Novoselov, M.A. Rassomakhin, R.R. Irmakov, A.E. Chugaev

“…The ore hand specimens and technological ore samples from the Porokhovskoe and Yugo-Konevskoe W greisen deposits in the South Urals are studied. The major W minerals of primary ores at both deposits include hübnerite and scheelite. …”
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Serum Fatty Acids and Risk of Cutaneous Melanoma: A Population-Based Case-Control Study by Marco Vinceti, Carlotta Malagoli, Laura Iacuzio, Catherine M. Crespi, Sabina Sieri, Vittorio Krogh, Sandra Marmiroli, Giovanni Pellacani, Elisabetta Venturelli

“…These findings do not suggest a major role of fatty acids, including linoleic acid, on risk of cutaneous melanoma, though their evaluation is limited by the small sample size.…”
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