A Six-Month Randomized Controlled Trial of Whole Soy and Isoflavones Daidzein on Body Composition in Equol-Producing Postmenopausal Women with Prehypertension by Zhao-min Liu, Suzanne C. Ho, Yu-ming Chen, Jean Woo

“…This paper reported the effects of commonly used whole soy foods (soy flour) and purified daidzein (one of the major isoflavones and the precursor of equol) on changes in anthropometric measurements and body composition in a 6-month double-blind, randomized, placebo-controlled trial among prehypertensive postmenopausal women who are also equol producers. …”
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Effect of Transplantation of Bone Marrow Derived Mesenchymal Stem Cells and Platelets Rich Plasma on Experimental Model of Radiation Induced Oral Mucosal Injury in Albino Rats by Basma Elsaadany, Samar El Kholy, Dalia El Rouby, Laila Rashed, Tarek Shouman

“…Normal tissue damage following radiotherapy is still a major problem in cancer treatment. Therefore, the current work aimed at exploring the possible role of systemically injected bone marrow derived mesenchymal stem cells (BM-MSCs) and/or locally injected platelet rich plasma (PRP) in ameliorating the side effects of ionizing radiation on the rat’s tongue. …”
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Patients Prefer Boarding in Inpatient Hallways: Correlation with the National Emergency Department Overcrowding Score by John R. Richards, Gal Ozery, Mark Notash, Peter E. Sokolove, Robert W. Derlet, Edward A. Panacek

“…The boarding of patients in Emergency Department (ED) hallways when no inpatient beds are available is a major cause of ED crowding. One solution is to board admitted patients in an inpatient rather than ED hallway. …”
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Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood by Heiner Falkenberg, Teja Falk Radke, Gesine Kögler, Kai Stühler

“…Despite the fact that haematopoetic cells still expressed CD34 on the surface after 3 days, major changes in regard to the protein profile were observed, while further expansion showed less effect on the proteome level. …”
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Association between composite dietary antioxidant index and hyperlipidemia in adults based on the NHANES by Kaidi Nie, Tingting Deng, Yiling Bai, Yuxian Zhang, Zhixuan Chen, Xile Peng, Lina Xia, Jiao Liu

“…Abstract Hyperlipidemia, a major risk factor for cardiovascular diseases, can potentially be alleviated by dietary antioxidants. …”
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Advances in liver organoids: replicating hepatic complexity for toxicity assessment and disease modeling by Weidong Shao, Hui Xu, Kanghua Zeng, Mingzhou Ye, Renjun Pei, Kai Wang

“…Liver organoids derived from human pluripotent stem cells, adult stem cells primary cells, or tissues can mimic diverse liver cell types, major physiological functions, and architectural features. …”
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Optimizing Steam Consumption of Mushroom Canning Process by Selecting Higher Temperatures and Shorter Time of Retorting by Didik J. Pursito, Eko H. Purnomo, Dedi Fardiaz, Purwiyatno Hariyadi

“…Since steam consumption is a major element of production costs in the canning industry, the selection of higher temperatures and shorter time of retorting will have a positive commercial impact due to the reduction of production costs.…”
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Precision measurement for effective pollution mitigation by evaluating air quality monitoring systems in linguistic Pythagorean fuzzy dombi environment by Hanan Alolaiyan, Umme Kalsoom, Umer Shuaib, Abdul Razaq, Abdul Wakil Baidar, Qin Xin

“…Abstract Air quality is a major concern for human health, with pollutants linked to respiratory problems and chronic illnesses. …”
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Increased Kappa/Lambda Hybrid Antibody in Serum Is a Novel Biomarker Related to Disease Activity and Inflammation in Rheumatoid Arthritis by Lang Yi, Mingju Hao, Tian Lu, Guigao Lin, Lida Chen, Ming Gao, Gaowei Fan, Dong Zhang, Guojing Wang, Xin Yang, Yulong Li, Kuo Zhang, Rui Zhang, Yanxi Han, Lunan Wang, Jinming Li

“…Rheumatoid arthritis (RA) is one of the major joint diseases, and the early diagnosis and treatment of RA remain a challenge. …”
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Progress in quality assessment of Italian saffron by Irene Locatelli, Davide Pedrali, Silvia Grassi, Susanna Buratti, Annamaria Giorgi, Luca Giupponi

“…Abstract Saffron (Crocus sativus L.) is the most expensive spice in the World, and Italy is among the major European producers. The study aims to improve value and recognition of high quality saffron by proposing a subdivision within the first quality category, according to ISO 3632 standards. …”
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Use of Antiviral Prophylaxis in Influenza Outbreaks in Long Term Care Facilities by Allison McGeer, Daniel S Sitar, Susan E Tamblyn, Faron Kolbe, Pamela Orr, Fred Y Aoki

“…Influenza is a major cause of illness and death in residents of long term care facilities for the elderly, in part because residents' age and underlying illness increase the risk of serious complications, and in part because institutional living increases the risk of influenza outbreaks. …”
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Bibliometric analysis of 100 most cited papers on oral proliferative verrucous leukoplakia by Namrata Sengupta, Gargi S. Sarode, Sachin C. Sarode

“…United States had the major contribution of papers (n = 28). There were 71 articles and 18 review papers in the top list. …”
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Calcium carbonate sediment corrosion and formation investigation in drinking water distribution network in Sough City, Iran by Abdol Hosein Salehi Sarvak, Seyed Ali Almodaresi, Abolghasem Mirhosseini Deh-abadi, Masoud Reza Shishehbore, Abdol Hosein Kangazian, Ali Akbar Jamali

“…Abstract One of the major problems facing the water industry is corrosion and sedimentation, which causes problems such as reduced water quality and the useful life of water supply network equipment. …”
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Downregulation of HBx Restrains Proliferation, Migration, and Invasion of HepG2 Cells by Chaoqun Huang, Wei Liu, Xiaochuan Zhao, Libin Zhao, Fuxiang Wang

“…Liver cancer is a major contributor to cancer-related death with poor survival for sufferers. …”
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An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance by Hang Zou, Pingping Wang, Zhihao Bai, Liping Liu, Jingtong Wang, Yanfang Cheng, Bairong He, Zujin Zhao, Lei Zheng

“…Therapeutic resistance is a major challenge in clinical cancer theranostics, often leading to treatment failure and increased patient mortality. …”
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Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids by Arun Sridhar, Ingunn Bakke, Shreya Gopalakrishnan, Nimo Mukhtar Mohamud Osoble, Emilie Prytz Hammarqvist, Henrik P. Sahlin Pettersen, Arne Kristian Sandvik, Ann Elisabet Østvik, Marianne Doré Hansen, Torunn Bruland

“…During homeostasis, epithelial renewal is maintained by crypt stem cells and progenitors that cease to divide as they differentiate into mature colonocytes. Inflammation is a major effector of mucosal damage in IBD and has been found to affect epithelial stemness, regeneration and cellular functions. …”
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A Facile Review on the Sorption of Heavy Metals and Dyes Using Bionanocomposites by Uyiosa Osagie Aigbe, Kingsley Eghonghon Ukhurebor, Robert Birundu Onyancha, Benedict Okundaye, Kaushik Pal, Otolorin Adelaja Osibote, Ese Lawrence Esiekpe, Heri Septya Kusuma, Handoko Darmokoesoemo

“…Presently, hazardous metal and dye removal from wastewater is one of the major areas of research focus. For the elimination of these contaminants, many approaches have been devised and applied. …”
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Spatiotemporal Variation and Abrupt Change Analysis of Temperature from 1960 to 2012 in the Huang-Huai-Hai Plain, China by Yanyu Yin, Hui Liu, Xiangsheng Yi, Weidong Liu

“…Based on a monthly dataset of temperature time series (1960–2012) in the Huang-Huai-Hai Plain of China (HHHPC), spatiotemporal variation and abrupt change analysis of temperature were examined by moving average, linear regression, spline interpolation, Mann-Kendall test, and moving t-test. Major conclusions were listed as follows. (1) Annual and seasonal temperature increased with different rates on the process of fluctuating changes during 1960~2012. …”
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Immune and Inflammation in Acute Coronary Syndrome: Molecular Mechanisms and Therapeutic Implications by Haiming Wang, Zifan Liu, Junjie Shao, Lejian Lin, Min Jiang, Lin Wang, Xuechun Lu, Haomin Zhang, Yundai Chen, Ran Zhang

“…Acute coronary syndrome (ACS) is a major cause of acute death worldwide. Both innate and adaptive immunity regulate atherosclerosis progression, plaque stability, and thrombus formation. …”
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Potential Biomarkers of Insulin Resistance and Atherosclerosis in Type 2 Diabetes Mellitus Patients with Coronary Artery Disease by Sharifah Intan Qhadijah Syed Ikmal, Hasniza Zaman Huri, Shireene Ratna Vethakkan, Wan Azman Wan Ahmad

“…Type 2 diabetes mellitus patients with coronary artery disease have become a major public health concern. The occurrence of insulin resistance accompanied with endothelial dysfunction worsens the state of atherosclerosis in type 2 diabetes mellitus patients. …”
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