Exponential forecasting of the monthly volume of the tourism receipts in Bulgaria by Preslav Dimitrov, Maria Kalinova, Gantcho Gantchev, Chavdar Nikolov

“…The present paper regards several major problems in the application of the exponential smoothing methods for the purpose of the long-run forecasting of the monthly volume of the tourism receipts in Bulgaria. …”
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Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal. by William J Cisneros, Shimaa H A Soliman, Miriam Walter, Lacy M Simons, Daphne Cornish, Simone De Fabritiis, Ariel W Halle, Eun-Young Kim, Steven M Wolinsky, Ramon Lorenzo-Redondo, Ali Shilatifard, Judd F Hultquist

“…Blocks to transcriptional elongation play a central role in maintaining the latent state, and several latency reversal strategies focus on the release of positive transcription elongation factor b (P-TEFb) from sequestration by negative regulatory complexes, such as the 7SK complex and BRD4. Another major cellular reservoir of P-TEFb is in Super Elongation Complexes (SECs), which play broad regulatory roles in host gene expression. …”
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Respiratory diseases in young cattle by T. S. Ermilova, M. A. Samburova, O. V. Kasharnaya, E. A. O. Salimzade

“…The group of pathologies under consideration is sufficiently diverse and can be caused by high animal density in the premises, overheating, hypothermia, unbalanced feeding, micronutrient deficiency, decreased body resistance, unfavorable epidemic situation and many other factors. However, out of the major calf diseases, particular mention should be made of pneumonia, which is most often caused by viruses. …”
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Characterization and Modelling of Multiscale Natural Fractures in Shale Reservoirs: A Case Study from a Block in the Southern Sichuan Basin by Shaohua Gai, Ailin Jia, Yunsheng Wei, Ruohan Liu

“…Comparing the histograms of DFN results and fracture characterized by seismic and logging responses, as well as outcrop and core observation, it suggests that the major part of the observed natural fractures is retained into our DFN model.…”
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Consensus guidelines for the management of treatment-naïve chronic lymphocytic leukaemia in Singapore (2024) by Yeow Tee Goh, Yvonne Loh, Esther Chan, Yuh Shan Lee, Venkata Sreekanth Sampath, Daryl Tan, Shin Yeu Ong, Chandramouli Nagarajan

“…Results: The final consensus included 15 statements covering major TN CLL patient subsets. The recommendations highlight the importance of molecular testing for key biomarkers, where available/accessible, to guide initial therapy. …”
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Optimal Charging Scheduling and Management with Bus-Driver-Trip Assignment considering Mealtime Windows for an Electric Bus Line by Yang Jiang, Tong He

“…Compared to a charging scheduling and management problem characterized by predetermined trip assignment, this study takes bus and driver scheduling into account, and mealtime windows must be guaranteed as one of the major labor regulations. A discretized mixed-integer linear programming (MIPL) model is developed based on a single electric bus route. …”
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Optimization of Data Distributed Network System under Uncertainty by Laxminarayan Sahoo, Supriyan Sen, Kalishankar Tiwary, Sovan Samanta, Tapan Senapati

“…The major network design or data distributed problems may be described as constrained optimization problems. …”
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Identifying and analysis the speculative factors affecting land use changes and activity (Case study:Gisha street in Tehran) by Reza kheyroddin, Nazanin Mostafavi Esfahani

“…Following this, changes in urban land demand as the spatial changes of activities and functions occur.The commercialization of residential areas and the tendency of residential landuse changes are the disadvantages of these changes,which constitute a major part of residential neighborhoods of Tehran metropolis ,especially the northern neighborhoods of the city. …”
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The pedestrian in west Africa’s town, the poor parent of mobility in the Sahelian city of Ouaga-Dougou in Burkina Faso by Soma Assonsi, Yameogo Lassane

“…It emerges that moving by foot every day in Ouagadougou is a major constraint for the wealthy or, above all, the poorest city dwellers. …”
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RUSSIA AND EAST ASIA: NEW OPPORTUNITIES AND CHALLENGES by A. A. Kireeva

“…The article focuses on major dimensions, achievements, challenges and prospects of relations between Russia and East Asia. …”
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Temporal and Spatial Pattern of Pulmonary Tuberculosis in Gansu Province and Its Environmental Factors Detection and Analysis by Haili Zhao, Jun Wang, Minghui Wu

“…As one of the major public health security issues, pulmonary tuberculosis had a global death rate of 1.6 million in 2021 alone, ranking 13th in the world, posing a great threat to society and families. …”
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Suvorexant, a Novel Dual Orexin Receptor Antagonist, for the Management of Insomnia by Andrew H. Han, Caroline R. Burroughs, Evan P. Falgoust, Jamal Hasoon, Grace Hunt, Juyeon Kakazu, Tim Lee, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“… # Summary Insomnia is a major public health concern that affects many people worldwide and has been linked to many adverse health outcomes. …”
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Segmenting tourism in rural area by emphasizing on motivational factors: Case study of Kolan river catchment area by Nasser Bayat, Seyed Ali Badri

“…Based on the results of factor analysis were identified even major factor in tourists' motivations at the regional level, including: Rurality, sense of place and place belonging, rest and relaxation, nature-based tourist activities, group outdoor recreational activities, purchase the rural production, excitement and novelty, spirituality and solitude. …”
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The development of preterm infants from low socio-economic status families: The combined effects of melatonin, autonomic nervous system maturation and psychosocial factors (ProMote... by Theano Kokkinaki, Nicole Anagnostatou, Maria Markodimitraki, Theano Roumeliotaki, Manolis Tzatzarakis, Elena Vakonaki, Giorgos Giannakakis, Aristidis Tsatsakis, Eleftheria Hatzidaki

“…Preterm births constitute a major public health issue and a chronic, cross-generational condition globally. …”
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Thresholds of Abnormality Perception in Facial Esthetics among Laypersons and Dental Professionals: Profile Esthetics by Raed H. Alrbata, Ayham Kh. Alfaqih, Mohammad R. Almhaidat, Ahmad M. Al-Tarawneh

“…To find thresholds at which laypersons and dental professionals from Jordanian population perceive abnormalities in sagittal positioning of upper and lower jaws as a major determinant to facial profile esthetics. Materials and Methods. …”
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Incident duration prediction through integration of uncertainty and risk factor evaluation: A San Francisco incidents case study. by Amirreza Salehi, Ardavan Babaei, Majid Khedmati

“…In this paper, we present a comprehensive framework for accurately predicting incident duration, with a particular emphasis on the critical role of street conditions and locations as major incident triggers. To demonstrate the effectiveness of our framework, we performed an in-depth case study using a dataset from San Francisco. …”
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Dilated Cardiomyopathy in Children and Adults: What is New? by Galal E. Nagib Elkilany, Mustafa A. AL-Qbandi, Khaled A. Sayed, Ibrahim Kabbash

“…In adults, low ejection fraction (<30–35%), global peak systolic strain <-7.6%, increased EDV, ESV, LBBB, diastolic dysfunction, and left ventricle dyssynchrony were the main independent risk factors for major cardiac events and need for CRT or transplantation (p < 0.001 for all). …”
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Growth performance study of Koi fish, Anabas testudineus (Bloch) by utilization of poultry viscera, as a potential fish feed ingredient, replacing fishmeal by Pratyush Bhaskar, Saroj Kumar Pyne, Arun Kumar Ray

“…Background In India, fishmeal is habitually considered as the major protein source for fish culture. Rising cost, deteriorating quality and unavailability of fishmeal caused huge difficulty in modern aquaculture, particularly for fish nutrition. …”
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Changes in the Serum Protein Fractions in Goats after Treatment of Natural Gastrointestinal Parasite Infections by Frederika Chovanová, Csilla Tóthová, Róbert Klein, Oskar Nagy

“…Gastrointestinal parasitic infections in small ruminants belong to major health problems. The regulation of gastrointestinal infections in goats and the responses developed against them appear to be different from those observed in sheep. …”
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Ex Vivo Antioxidant Activity of Selected Medicinal Plants against Fenton Reaction-Mediated Oxidation of Biological Lipid Substrates by Namratha Pai Kotebagilu, Vanitha Reddy Palvai, Asna Urooj

“…Biological substrates with lipids as major components are susceptible to oxygen-derived lipid peroxidation due to their composition. …”
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