Comparative Quality Evaluation of Selected Brands of Cefuroxime Axetil Tablets Marketed in the Greater Accra Region of Ghana by Christina Osei-Asare, Esther Eshun Oppong, Frederick William Akuffo Owusu, John Antwi Apenteng, Yvonne Ochesinda Alatu, Robert Sarpong

“…The ever-growing commercialization of poor-quality and substandard medicines, especially anti-infectives characterized by inadequate postmarket surveillance by stakeholders remains a major global health challenge, particularly in developing countries, where antibiotic drug resistance and its repercussions on human health remain dominant. …”
Get full text

Heterogeneity in Seed Samples from Vineyards and Natural Habitats Along the Eurasian <i>Vitis vinifera</i> Range: Implications for Domestication and Hybridization by Diego Rivera, Javier Valera, David Maghradze, Maia Kikvadze, Anna Nebish, Rafael Ocete, Carlos Álvar Ocete, Claire Arnold, Emilio Laguna, Francisco Alcaraz, Diego José Rivera-Obón, Gianni Lovicu, Massimino Farci, Concepción Obón

“…The results demonstrate the significance of these mixed populations as repositories of genetic diversity, underscoring their conservation value, particularly considering the negative impact of habitat alterations, especially in riparian forests due to major public works.…”
Get full text

Quantifying impacts of two ENSO patterns on South China sea summer monsoon onset by Lianyi Zhang, Junshu Lin, Zesheng Chen, Yanping Shi, Yan Du

“…The onset date is significantly affected by the El Niño-Southern Oscillation (ENSO), which manifests as two major types: the Eastern-Pacific (EP) and Central-Pacific (CP) patterns. …”
Get full text

A Coverage and Slicing Dependencies Analysis for Seeking Software Security Defects by Hui He, Dongyan Zhang, Min Liu, Weizhe Zhang, Dongmin Gao

“…Software security defects have a serious impact on the software quality and reliability. It is a major hidden danger for the operation of a system that a software system has some security flaws. …”
Get full text

Antigenotoxic Effect of Curcumin and Carvacrol against Parathion Induced DNA Damage in Cultured Human Peripheral Blood Lymphocytes and Its Relation to GSTM1 and GSTT1 Polymorphism by Neeraj Kumar, Anita Yadav, Sachin Gulati, Kanupriya, Neeraj Aggarwal, Ranjan Gupta

“…In recent years, the use of organophosphorus pesticides has been extensively increased and these compounds signify a major class of agricultural pesticides today. We studied antigenotoxic potential of curcumin and carvacrol against the parathion induced DNA damage in cultured peripheral blood lymphocytes using sister chromatid exchanges as a biomarker of genotoxicity. …”
Get full text

A data-driven cluster analysis to explore cognitive reserve and modifiable risk factors in early phases of cognitive decline by Sara Bernini, Alice Valcarenghi, Elena Ballante, Federico Fassio, Marta Picascia, Elena Cavallini, Matteo Cotta Ramusino, Alfredo Costa, Tomaso Vecchi, Cristina Tassorelli, Sara Bottiroli

“…Abstract The present study was aimed to cluster sub-groups of patients with varying degrees of cognitive impairment (Subjective Cognitive Decline, mild or Major Neurocognitive Disorder) based on their modifiable risk factors and cognitive reserve with k-means analysis. …”
Get full text

Predicting emergency department admissions using a machine-learning algorithm: a proof of concept with retrospective study by Cyrielle Brossard, Christophe Goetz, Pierre Catoire, Lauriane Cipolat, Christophe Guyeux, Cédric Gil Jardine, Mahuna Akplogan, Laure Abensur Vuillaume

“…Abstract Introduction Overcrowding in emergency departments (ED) is a major public health issue, leading to increased workload and exhaustion for the teams, resulting poor outcomes. …”
Get full text

A deep learning ICDNET architecture for efficient classification of histopathological cancer cells using Gaussian noise images by Hui Zong, Wenlong An, Xin Chen, Zhanhui Yang, Heng Zhou, Xiangchao Liu, Jianchu Lin, Chuanyue Zong

“…To evaluate the performance of the ICDNET network model, experiments were conducted on four major public datasets with the addition of Gaussian noise. …”
Get full text

The built environment and place attachment: Insights from Japanese cities by Jiuling Li, Mohammad Javad Koohsari, Andrew T. Kaczynski, Ryo Tanimoto, Reo Watanabe, Tomoki Nakaya, Yufeng Luo, Jing Zhao, Akitomo Yasunaga, Koichiro Oka, Tomoya Hanibuchi

“…Methods: This study used data collected from October to November 2020, involving 25,340 adults across 21 major cities in Japan. Geographic address information was used to measure objective walkability, while perceived walkability and place attachment were assessed using adapted scales. …”
Get full text

Theoretical assessment of the relative incidences of sensitive andresistant tuberculosis epidemic in presence of drug treatment by Silvia Martorano Raimundo, Hyun Mo Yang, Ezio Venturino

“…Despite the availability of effective treatment, tuberculosis (TB)remains a major global cause of mortality.Multidrug-resistant tuberculosis (MDR-TB) is a form of TB thatis resistant to at least two drugs used for the treatment of TB,and originally is developed when a case of drug-susceptibleTB is improperly or incompletely treated.This work is concerned with a mathematical model to evaluate the effect ofMDR-TB on TB epidemic and its control.The model assessing the transmission dynamics of both drug-sensitive anddrug-resistant TB includes slow TB(cases that result from endogenous reactivation of susceptible andresistant latent infections). …”
Get full text

The Strong Protective Effect of Circumcision against Cancer of the Penis by Brian J. Morris, Ronald H. Gray, Xavier Castellsague, F. Xavier Bosch, Daniel T. Halperin, Jake H. Waskett, Catherine A. Hankins

“…Male circumcision protects against cancer of the penis, the invasive form of which is a devastating disease confined almost exclusively to uncircumcised men. Major etiological factors are phimosis, balanitis, and high-risk types of human papillomavirus (HPV), which are more prevalent in the glans penis and coronal sulcus covered by the foreskin, as well as on the penile shaft, of uncircumcised men. …”
Get full text

Enhancing ophthalmology education through a mobile flipped classroom: a new teaching method by Maryam Yadgari, Masomeh Kalantarion, Mohammad-Mehdi Sadoughi, Soleiman Ahmady, Mohammad-Hasan Shahriari

“…Abstract Objective Glaucoma is a major cause of irreversible blindness globally. Optical coherence tomography (OCT) aids early glaucoma diagnosis. …”
Get full text

Dynamic simulation of breast behaviour during different activities based on finite element modelling of multiple components of breast by Jiazhen Chen, Zejun Zhong, Yue Sun, Joanne Yip, Kit-lun Yick

“…The magnitude of the stress distribution and effect of activity intensity on the stress experienced by the breast internal components are in ascending order: the glandular tissues, pectoralis major muscles, adipose tissues, and Cooper’s ligaments, thus highlighting the different biomechanical response of these breast components to dynamic stress. …”
Get full text

Online Monitoring Oxidative Products and Metabolites of Nicotine by Free Radicals Generation with Fenton Reaction in Tandem Mass Spectrometry by Shih-Shin Liang, Yow-Ling Shiue, Chao-Jen Kuo, Su-Er Guo, Wei-Ting Liao, Eing-Mei Tsai

“…In general, over 70% absorbed nicotine is metabolized to cotinine and trans-3′-hydroxycotinine by cytochrome oxidase P450, and nicotine is also a major addictive and the psychoactive component in cigarettes. …”
Get full text

Application of spent Agaricus subrufescens compost in integrated production of seedlings and plants of tomato by Raul Xavier Lopes, Diego Cunha Zied, Emerson Tokuda Martos, Rovilson José De Souza, Romildo Da Silva, Eustáquio Souza Dias

“…Purpose Spent mushroom compost (SMC) is a major solid waste product of the mushroom industry and is the material which remains at the end of a mushroom crop. …”
Get full text

Clinical and Laboratory Diagnosis of Buruli Ulcer Disease: A Systematic Review by Samuel A. Sakyi, Samuel Y. Aboagye, Isaac Darko Otchere, Dorothy Yeboah-Manu

“…Current efforts aimed at developing point-of-care diagnostics are saddled with major drawbacks; we, however, postulate that selection of aptamers against MU target can be used as point of care.…”
Get full text

Topic Analysis of the Literature Reveals the Research Structure: A Case Study in Periodontics by Carlo Galli, Maria Teresa Colangelo, Marco Meleti, Stefano Guizzardi, Elena Calciolari

“…We identified 31 broad topics encompassing four major thematic axes—patient management, periomedicine, oral microbiology, and implant-related surgery—thereby illuminating core areas and their semantic relationships. …”
Get full text

Integrated Pest Management of Wireworms in Potatoes: Use of Tolerant Varieties to Implement Damage Prevention by Furlan Lorenzo, Bona Stefano, Benvegnù Isadora, Cacitti Valentina, Govoni Fausto, Parisi Bruno

“…., Coleoptera, Elateridae) are a major threat to potatoes, as are the current commercial standards for assessing potato damage. …”
Get full text

Advanced Piezoelectric Materials, Devices, and Systems for Orthopedic Medicine by Jingkai Zhang, Chang Liu, Jun Li, Tao Yu, Jing Ruan, Fan Yang

“…A comprehensive overview of piezoelectric materials, devices, and systems enhancing bone tissue repair, alleviating inflammation at infection sites, and monitoring bone health is then provided, respectively. Finally, the major challenges faced by applications of piezoelectricity in orthopedic conditions are thoroughly discussed, along with a critical outlook on future development trends.…”
Get full text

JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells by Ling Yan, Shengnan Liu, Chen Wang, Fei Wang, Yingli Song, Nan Yan, Shuhua Xi, Ziyou Liu, Guifan Sun

“…In CNS, activated microglial cells can release more reactive oxygen species (ROS), and NADPH oxidase (NOX) is the major enzyme for the production of extracellular superoxide in microglia. …”
Get full text