A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology by Yingying Zhang, Alden K. Leung, Jin Joo Kang, Yu Sun, Guanxi Wu, Le Li, Jiayang Sun, Lily Cheng, Tian Qiu, Junke Zhang, Shayne D. Wierbowski, Shagun Gupta, James G. Booth, Haiyuan Yu

“…Abstract A major goal of cancer biology is to understand the mechanisms driven by somatically acquired mutations. …”
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Performance Driven Six-Port Receiver and Its Advantages over Low-IF Receiver Architecture by Abul Hasan, Mohamed Helaoui

“…The main advantages and disadvantages of the SPR compared to the low-IF receiver are highlighted. The major advantages of the SPR come in terms of its available input frequency bandwidth and the low power requirement. …”
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Application of EMG feedback for hand prosthesis control in high-level amputation: a case study by Jack Tchimino, Rehne Lessmann Hansen, Peter Holmberg Jørgensen, Jakob Dideriksen, Strahinja Dosen

“…The present study aimed to test if this method can be used by a participant with a high-level amputation, and whose muscle used for prosthesis control (pectoralis major) was not intuitively related to hand function. …”
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Prevalence of Atopic Dermatitis Among Children Under 19 in an East-Hungarian Agricultural County by Agnes Kuhnyar, Katalin Egyud, Imre Szabo, Janos Hunyadi, Lajos Kosa

“…Data suggest that premature abruption of breast feeding maybe one of the major factors among other environmental factors that is contributing to the development of AD.…”
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A Critical Review on the Book Transformation of the Foundations of the Legitimacy of the Monarchy: From the Mongol Invasion to the Rise of the Safavids by Abdollah Sajedi, Hooshang Khosrobigi

“…This study shows that the crisis of legitimacy was a major issue in the period under review, but the patterns of legitimacy were by no means based on a single pattern, but on a multifaceted, composite, and simultaneous pattern, but important indicators such as the Iranian idea of monarchy; Farah Izadi and Farah Kiani were ignored. …”
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Effectiveness of Palivizumab in Preventing RSV Hospitalization in High Risk Children: A Real-World Perspective by Nusrat Homaira, William Rawlinson, Thomas L. Snelling, Adam Jaffe

“…Infection with respiratory syncytial virus (RSV) is one of the major causes globally of childhood respiratory morbidity and hospitalization. …”
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Multi-omics approach in tea polyphenol research regarding tea plant growth, development and tea processing: current technologies and perspectives by Jingwen Li, Yu Wang, Joon Hyuk Suh

“…Although omics has been used as a major analytical platform for tea polyphenol research with some proven merits, a single-omics strategy remains a considerable challenge due to the complexity of biological system and functional processes of tea in each stage of tea production. …”
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Anti-Biofilm Agents to Overcome <i>Pseudomonas aeruginosa</i> Antibiotic Resistance by Marie Hanot, Elodie Lohou, Pascal Sonnet

“…Particularly, its ability to form biofilms that protect colonies from antimicrobial agents is a major cause of chronic and hard-to-treat infections in immune-compromised patients. …”
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Implementation of Blended Learning in Southern African Marginalised Higher Education Eclectic Contexts by Patricia Muhuro, Simon Murote Kang’ethe

“…The study employed a literature review method using 20 relevant studies extracted from major databases. Data were analysed using thematic analysis. …”
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Typical and extreme weather datasets for studying the resilience of buildings to climate change and heatwaves by Anaïs Machard, Agnese Salvati, Mamak P. Tootkaboni, Abhishek Gaur, Jiwei Zou, Liangzhu Leon Wang, Fuad Baba, Hua Ge, Facundo Bre, Emmanuel Bozonnet, Vincenzo Corrado, Xuan Luo, Ronnen Levinson, Sang Hoon Lee, Tianzhen Hong, Marcelo Salles Olinger, Rayner Maurício e Silva Machado, Emeli Lalesca Aparecida da Guarda, Rodolfo Kirch Veiga, Roberto Lamberts, Afshin Afshari, Delphine Ramon, Hoang Ngoc Dung Ngo, Abantika Sengupta, Hilde Breesch, Nicolas Heijmans, Jade Deltour, Xavier Kuborn, Sana Sayadi, Bin Qian, Chen Zhang, Ramin Rahif, Shady Attia, Philipp Stern, Peter Holzer

“…Abstract We present unprecedented datasets of current and future projected weather files for building simulations in 15 major cities distributed across 10 climate zones worldwide. …”
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Techno-economic aspects of concrete lightweighting by char enrichment with phosphates from wastewater by Josef Marousek, Beata Gavurova, Anna Marouskova, Babak Minofar

“…Portland cement (PC) production is a major contributor to environmental pollution due to its resource and energy – intensive nature, ranking as the 3rd largest source. …”
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Hemodynamic Effect of Unequal Anterior Cerebral Artery Flow Rates on the Anterior Communicating Artery Bifurcation: A Computational... by Thomas Rau, Xing He, Prem Venugopal, Fernando Viñuela, Gary Duckwiler, Daniel J. Valentino

“…Hemodynamics have long been implicated as a major factor in cerebrovascular disease. Using an idealized 2D symmetric model of the ACA-ACOM geometry, the flow field and wall shear stress (WSS) at the bifurcation regions are assessed for pulsatile inflows with left to right flow ratios of 1:1, 2:1, 3:1, and 4:1. …”
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Phytochemical composition and antimicrobial activity of essential oil from the leaves of Peganum harmala L.  in southern Algeria. by Abderrahmane Ghillace, Ourida Chouitah, Fatima Zohra Kiari, Zineb Fergoug, Zineeddine Daikh

“…These essential oils contain the same major components for Bougtob region Carvone (21.15%), Phytol (17.41%), Carbamic acid (3.52%), Lauric acid (2.10%), and Thymol (1.77%) and Tetrapentacontane (1.32%). …”
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Mechanism of Inflammation in Age-Related Macular Degeneration by Francesco Parmeggiani, Mario R. Romano, Ciro Costagliola, Francesco Semeraro, Carlo Incorvaia, Sergio D’Angelo, Paolo Perri, Paolo De Palma, Katia De Nadai, Adolfo Sebastiani

“…In the aging retina, free radicals and oxidized lipoproteins are considered to be major causes of tissue stress resulting in local triggers for parainflammation, a chronic status which contributes to initiation and/or progression of many human neurodegenerative diseases such as AMD. …”
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Combining two parasitoids (Asecodes hispinarum and Tetrastichus brontispae) for biological control of coconut leaf beetle by Qikai Zhang, Bin Jiao, Hui Lu, Jihong Tang, Xu Zhang, Baoqian Lyu

“…The coconut leaf beetle (CLB), Brontispa longissima, is a major threat to coconut production worldwide, causing widespread and important losses throughout the tropics. …”
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Medicine Students’ Opinions on the English Discipline. University Polyclinic "Fabio Di Celmo" by Maira Pérez Pérez, Geisi Fernández Gómez, Isabel del Rosario Bagattín Martínez, Ditza Viera Álvarez, Maicel Eugenio Monzón Pérez

“…Variables that were considered: the actual need to teach English, students’ major motivations and satisfaction level with the educational process. …”
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Analysis of the Deployment Quality for Intrusion Detection in Wireless Sensor Networks by Noureddine Assad, Brahim Elbhiri, Moulay Ahmed Faqihi, Mohamed Ouadou, Driss Aboutajdine

“…The deployment quality of sensor nodes depends directly on node density and sensing range; mainly a random sensor nodes deployment is required. The major question is centred around the problem of network coverage, how can we guarantee that each point of the sensing area is covered by the required number of sensor nodes and what a sufficient condition to guarantee the network coverage? …”
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A step forward in enhancing the health-promoting properties of whole tomato as a functional food to lower the impact of non-communicable diseases by Pier Giorgio Natali, Pier Giorgio Natali, Mauro Piantelli, Alessandra Sottini, Margherita Eufemi, Cristina Banfi, Luisa Imberti

“…Given that the complex of tomato micronutrients produces healthier outcomes than lycopene, its major antioxidant component, new strategies to improve the health-supporting properties of the berry are ongoing. …”
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Fatigue behavior of lubricated Ni-Ti endodontic rotary instruments by A. Brotzu, F. Felli, C. Lupi, C. Vendittozzi, E. Fantini

“…Although they have many advantages and despite their increasing popularity, a major concern with the use of Ni-Ti rotary instruments is the possibility of unexpected failure in use due to several reasons: novice operator handling, presence manufacturing defects, fatigue etc. …”
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Optimization of Open Boundary Conditions in a 3D Internal Tidal Model with the Adjoint Method around Hawaii by Anzhou Cao, Haibo Chen, Jicai Zhang, Xianqing Lv

“…Careful inspection shows that the major difference between simulated results and OSU model results is short-scale fluctuations superposed on coamplitude lines, which can be treated as the surface manifestation modulated by the internal tide. …”
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