Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity by Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N. Lundström, Jian Zeng, Naomi R. Wray, Yi Lu, Patrick F. Sullivan, Jens Hjerling-Leffler

“…By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. …”
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Resolution of depression: Antidepressant actions of resolvins by Satoshi Deyama, Katsuyuki Kaneda, Masabumi Minami

“…Major depressive disorder, one of the most widespread mental illnesses, brings about enormous individual and socioeconomic consequences. …”
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An Active Inference Model of the Optimism Bias by Elizabeth L. Fisher, Christopher J. Whyte, Jakob Hohwy

“…Associated with improved quality of life, optimism bias is considered to be adaptive and is a promising avenue of research for mental health interventions in conditions where individuals lack optimism such as major depressive disorder. Here we lay the groundwork for future research on optimism as an intervention by introducing a domain general formal model of optimism bias, which can be applied in different task settings. …”
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Social connectedness as a determinant of mental health: A scoping review. by Priya J Wickramaratne, Tenzin Yangchen, Lauren Lepow, Braja G Patra, Benjamin Glicksburg, Ardesheer Talati, Prakash Adekkanattu, Euijung Ryu, Joanna M Biernacka, Alexander Charney, J John Mann, Jyotishman Pathak, Mark Olfson, Myrna M Weissman

“…Among 8 of 9 studies that focused on loneliness, feeling lonely at baseline was related to adverse outcomes at follow-up including higher risks of major depressive disorder, depressive symptom severity, generalized anxiety disorder, and lower levels of physical activity. …”
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Effect of acupuncture on patients with major psychiatric disorder and related symptoms caused by earthquake exposure: Protocol for a scoping review of clinical studies. by Hui-Ju Kwon, Jungtae Leem, Da-Woon Kim, Chan-Young Kwon, Sang-Ho Kim

“…Posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and anxiety disorder (AD) are major psychiatric disorders (MPD) that can be triggered by exposure to earthquakes. …”
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On the Differential Diagnosis of Anxious from Nonanxious Major Depression by means of the Hamilton Scales by George Konstantakopoulos, Vasilios G. Masdrakis, Manolis Markianos, Panagiotis Oulis

“…Objective. Anxious major depressive disorder (A-MDD) is differentially diagnosed from nonanxious MDD (NA-MDD) as MDD with a cut-off score ≥7 on the HAM-D anxiety-somatization factor (ASF). …”
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Modified Electroconvulsive Therapy in a Patient with Gastric Adenocarcinoma and Metastases to Bone and Liver by Gennie Wang, Brian Milne, Rachel Rooney, Tarit Saha

“…We present a successful case of ECT to treat chronic major depressive disorder in a 62-year-old woman at high risk of bone fracture due to gastric adenocarcinoma with metastases to bone and liver. …”
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Mindfulness-based (non-contact) boxing therapy (MBBT) for depression and anxiety: A feasibility study. by Johny Bozdarov, Brett D M Jones, Madeha Umer, Daniel M Blumberger, Ishrat M Husain

“…The current study tested the acceptability and feasibility of delivering MBBT to adults with major depressive disorder (MDD) or generalized anxiety disorder (GAD).…”
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Autobiographical Memory Disturbances in Depression: A Novel Therapeutic Target? by Cristiano A. Köhler, André F. Carvalho, Gilberto S. Alves, Roger S. McIntyre, Thomas N. Hyphantis, Martín Cammarota

“…Major depressive disorder (MDD) is characterized by a dysfunctional processing of autobiographical memories. …”
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A cross-sectional study on psychiatric comorbidity, coping strategies, and quality of life in women diagnosed with breast and cervical cancers attending a tertiary care center in S... by Susila Sharmili Kumaravel, Niranjana Devi Andisamy, Praveena Daya Appadurai, Thenmozhi Lakshmanamoorthy, Ayyakutti Muni Raja, Rajeshwari Kathiah, Arumuganathan Shanmugavinayagam

“…Comorbid psychiatric illnesses were found in 41.2% of cervical and 32.4% of breast cancer participants. Major depressive disorder (20.6% cervical; 8.8% breast) and generalized anxiety disorder (8.8% each) were common. …”
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Perfectionistic Self-Presentation and Suicide in a Young Woman with Major Depression and Psychotic Features by Sabrina Hassan, Gordon L. Flett, Rohan Ganguli, Paul L. Hewitt

“…A woman in her midtwenties with a history of major depressive disorder and a recent major depressive episode with mood-congruent psychotic features died by suicide. …”
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A network-based analysis anticipates time to recovery from major depression revealing a plasticity by context interplay by Claudia Delli Colli, Aurelia Viglione, Silvia Poggini, Francesca Cirulli, Flavia Chiarotti, Alessandro Giuliani, Igor Branchi

“…Abstract Predicting disease trajectories in patients with major depressive disorder (MDD) can allow designing personalized therapeutic strategies. …”
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Obsessive-Compulsive Disorder with Suicide Obsessions in a First Responder without Previous Diagnosis of OCD or History of Suicide Attempts by Vivekananda Rachamallu, Michael M. Song, Haiying Liu, Charles L. Giles, Terry McMahon

“…There are many published studies reporting higher risk of suicidality in OCD patients, as well as studies describing increased risk of suicidality in OCD patients with other comorbid psychiatric conditions such as major depressive disorder (MDD) and posttraumatic stress disorder (PTSD). …”
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Using tree-based models to identify factors contributing to trait negative affect in adults by Catalina Cañizares, Yvonne Gómez-Maquet, Eugenio Ferro, Carlos Arturo Torres, Diana María Agudelo, Gabriel Odom

“…Theoretical models suggest that NA plays a critical role in psychopathology, particularly in Major Depressive Disorder (MDD), and is linked to cognitive-perceptual and affective regulation issues. …”
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Inside the impulsive brain: a narrative review on the role of neurobiological, hormonal and genetic factors influencing impulsivity in psychiatric disorders by Hannah Raji, Susha Dinesh, Sameer Sharma

“…Hormones, such as leptin and ghrelin, in conjunction with the hypothalamic–pituitary–adrenal axis, play pivotal roles in conditions like major depressive disorder. Concurrently, leptin resistance exerts influence over appetite and mood regulation. …”
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Prevalence of depressive disorders among pregnant women in Brazil in 2019: A descriptive cross-sectional study by Maira Gonçalves de Oliveira Lucas, Maria Isabel do Nascimento

“…Using the PHQ-9, the prevalence of Major Depressive Disorder (MDD) in the current pregnancy was estimated to be 17.39% (95%CI: 12.70%–22.06%) among pregnant women who were targeted by the PNS-2019. …”
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Interventions promoting recovery from depression for patients transitioning from outpatient mental health services to primary care: Protocol for a scoping review. by Anne Sofie Aggestrup, Frederik Martiny, Maria Faurholt-Jepsen, Morten Hvenegaard, Robin Christensen, Annette Sofie Davidsen, Klaus Martiny

“…<h4>Introduction</h4>Patients with severe Major Depressive Disorder (MDD) have an increasing risk of new psychiatric hospitalizations following each new episode of depression highlighting the recurrent nature of the disorder. …”
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New Therapeutic Targets for Mood Disorders by Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Lobna Ibrahim, David Latov, Cristina Wheeler-Castillo, Jacqueline Baumann, Ioline D. Henter, Carlos A. Zarate

“…Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. …”
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Role of Ketamine in the Treatment of Psychiatric Disorders by Sahar Derakhshanian, Maxine Zhou, Alexander Rath, Rachel Barlow, Sarah Bertrand, Caroline DeGraw, Christopher Lee, Jamal Hasoon, Alan D. Kaye

“…It covers the epidemiology, risk factors, pathophysiology, and current treatment modalities regarding Major Depressive Disorder (MDD) and TRD. It provides background on the mechanism of action of ketamine, its history, current approved and off-label indications in the field of psychiatry, and then provides an overview of the existing evidence for the use of ketamine in the treatment of TRD…”
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Predicting treatment response to ketamine in treatment-resistant depression using auditory mismatch negativity: Study protocol. by Josh Martin, Fatemeh Gholamali Nezhad, Alice Rueda, Gyu Hee Lee, Colleen E Charlton, Milad Soltanzadeh, Karim S Ladha, Sridhar Krishnan, Andreea O Diaconescu, Venkat Bhat

“…<h4>Background</h4>Ketamine has recently attracted considerable attention for its rapid effects on patients with major depressive disorder, including treatment-resistant depression (TRD). …”
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