Global, regional and national burden of neuroblastoma and other peripheral nervous system tumors, 1990 to 2021 and predictions to 2035: visualizing epidemiological characteristics... by Chaoyan Yue, Qi Zhang, Fenyong Sun, Qiuhui Pan

“…The age distribution shows that children under 5 years of age are mainly affected, especially in low- and middle-income areas. …”
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The Effects of Statin Dose, Lipophilicity, and Combination of Statins plus Ezetimibe on Circulating Oxidized Low-Density Lipoprotein Levels: A Systematic Review and Meta-Analysis o... by Tannaz Jamialahmadi, Fatemeh Baratzadeh, Željko Reiner, Luis E. Simental-Mendía, Suowen Xu, Andrey V. Susekov, Raul D. Santos, Amirhossein Sahebkar

“…Elevated plasma low-density lipoprotein cholesterol (LDL-C) is the main risk factor for atherosclerotic cardiovascular disease (ASCVD). …”
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Developing and testing the feasibility of a theory-based brief counseling intervention to promote physical activity in breast cancer survivors enrolled in the PAC-WOMAN trial by Sofia Franco, Eliana V. Carraça, Inês Nobre, Bruno Rodrigues, Vítor Ilharco, Lea Kahlert, Marlene N. Silva

“…Key strategies from each intervention helped shape the main components and BCTs used in the eight bimonthly sessions of the PAC-WOMAN brief counseling intervention, which was based on self-determination theory principles and aimed at empowering participants to develop self-regulation resources for PA through basic psychological needs satisfaction. …”
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Adopting Positive Selection Technology and Improving Seed Quality in Smallholder Potato Farmers in South-Western Uganda. by Kajura, Tibanyendera Deo

“…To address this, technologies and innovations such as Positive Selection technology have been developed and promoted among smallholders to enable them generate their own clean seed on-farm for increased productivity. The main objective of the study was to assess the adoption of Positive Selection Technology and improvement of seed quality by smallholder potato farmers. …”
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A randomised, double-masked, placebo-controlled trial evaluating the efficacy and safety of teprotumumab for active thyroid eye disease in Japanese patientsResearch in context by Yuji Hiromatsu, Eri Ishikawa, Ai Kozaki, Yasuhiro Takahashi, Mika Tanabe, Ken Hayashi, Yukihiro Imagawa, Kazutoyo Kaneda, Masashi Mimura, Xiaoxian Dai, Tomoko Hayashida, Takashi Akamizu

“…Methods: This randomised, double-masked, placebo-controlled trial was conducted in 16 centres in Japan. Main inclusion criteria were as follows: age 20–80 years; Graves’ disease, in a euthyroid or mild hypo/hyperthyroid state; clinical activity score (CAS) ≥3; moderate-to-severe TED; ≥3-mm increase in proptosis before TED onset and/or proptosis ≥18 mm at baseline; and TED duration ≤9 months. …”
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Causally inferred evidence of the impact of green and blue spaces (GBS) on maternal and neonatal health: a systematic review and meta-analysis by Rukun K S Khalaf, Selin Akaraci, Faye D Baldwin, Rebecca S Geary, Ruwanthi Kolamunnage-Dona, Ruth F Hunter, Sarah E Rodgers

“…Studies exploring the impact of GBS exposure on maternal, prenatal, and/or neonatal health have mainly utilised cross-sectional methods. This does not allow for causal inference. …”
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Biogeochemical cycling of sedimentary organic carbon and benthic nutrient fluxes in the semi-enclosed Jinhae Bay, Korea: insights into benthic-pelagic coupling by Sung-Uk An, Sung-Uk An, Kyung-Tae Kim, Sung-Han Kim, Sung-Han Kim, Ju-Wook Baek, Ju-Wook Baek, Hyun-Jeong Jeong, Hyun-Jeong Jeong, Chul-In Sun, Jin Young Choi, Jin Young Choi, Sokjin Hong, Dae In Lee, Jae Seong Lee, Jae Seong Lee

“…The vertical flux of organic carbon ranged from 45.5 ± 7.0 to 93.0 ± 25.3 mmol C m-2 d–1, and mainly consisted of biodeposits associated with aquaculture activities. …”
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Longitudinal impact of cross-clamp duration on postoperative sleep disturbance and quality of life in elderly cardiac surgery patients: a secondary analysis of the MINDDS trial by Grace E. Namirembe, Jamie Sparling, Alexis Novak, Ariel Mueller, Julia Bertsch, Kwame Wiredu, Jason Z. Qu, M. Brandon Westover, Timothy T. Houle, Oluwaseun Akeju

“…ObjectivesThis study aimed to assess the enduring impact of cross-clamp duration on postoperative sleep disturbance and functional outcomes (up to 180 days) in cardiac surgery patients.DesignThis is a secondary analysis of data from a randomized, double-blind trial comparing dexmedetomidine to placebo for delirium prevention (Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep).SettingData from patients recruited at a tertiary medical center in Boston, Massachusetts, between March 2017 and February 2022 were analyzed in January 2024.ParticipantsThe study included 394 patients aged ≥60 who underwent cardiac surgery with cardiopulmonary bypass.InterventionsThe primary exposure was cross-clamp time, while secondary exposures included surgical type [isolated coronary artery bypass graft (CABG) or not] and dexmedetomidine randomization.Measurements and main resultsThe primary outcome was sleep quality, assessed using the PROMIS Sleep Disturbance questionnaire at 30, 90, and 180 days postoperatively. …”
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Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms by Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra

“…BackgroundMyelodysplastic neoplasms (MDS) are characterized by ineffective hematopoiesis, peripheral blood cytopenias, and an increased risk of progression to acute myeloid leukemia. One of the main treatment goals is improving quality of life (QoL), particularly for patients with lower-risk MDS (LR-MDS) who may live longer with compromised QoL. …”
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Efficacy and safety of first-line or second-line selective laser trabeculoplasty for normal-tension glaucoma: a multicentre cohort study by Tomoko Naito, Kazuyuki Hirooka, Toru Nakazawa, Masaki Tanito, Shiro Mizoue, Katsuyoshi Suzuki, Keiji Yoshikawa, Itaru Kimura, Yasushi Ikuno, Takako Miki, Kazuhisa Sugiyama, Tairo Kimura, Akiko Narita, Tadashi Nakano, Tomoyuki Watanabe, Koji Nitta, Kae Sugihara, Maki Katai, Takuji Matsuda, Hiroaki Ozaki, Kaori Komatsu, Yoshiaki Saito, Takeshi Sagara, Aika Tsutsui, Akiko Ishida, Satoru Tsuda, Toyoaki Tsumura, Naoki Tojo, Naoto Tokuda, Kenji Nakamoto, Naka Shiratori, Mami Nanno, Naoya Nezu, Yoshitaka Tasaka, Shigeru Mori, Shigeki Yamabayashi, Kimihito Konno, Miyuki Domoto

“…Patients were treated with SLT as a first-line or second-line treatment for NTG. Main outcome measures were intraocular pressure (IOP) reduction rate, outflow pressure improvement rate (ΔOP), success rate at 1 year and complications. …”
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Transcriptomic and metabolomic analyses reveal the mechanism of color difference between two kinds of Cistanche deserticola before and after drying by Tiantian Zhu, Tiantian Zhu, Tiantian Zhu, Jing Zhang, Tianle Liu, Shuai Zhang, Baimei Yang, Li Xu, Lei Zhao, Lei Zhao, Mengfei Li, Ling Jin, Ling Jin, Ling Jin

“…In addition, the contents of iridoid and polysaccharide in oil cistanche were significantly higher than those in cistanche.DiscussionThe differential expression of flavonoids and terpenoid differential metabolites and CYP84A1, 5MAT1, FLS, UGT85A24 and CCD7 mainly caused the purple color of fresh oil cistanche. …”
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Deployment and uptake of COVID-19 vaccines for refugees and migrants in regular and irregular situations: a mixed-method multicountry study by Biraj Man Karmacharya, Karl Blanchet, Jai K Das, Laetitia Nyirazinyoye, Maria Midea M Kabamalan, Nguyen Toan Tran, Zahra A Padhani, Anjali Joshi, Seyed-Moeen Hosseinalipour, Enrique Teran, Pierina Benavente, Vinay N Kampalath, Moussa Lonkila Zan, Elżbieta Anna Czapka, Cheryl Martens, Vicente B Jurlano

“…Both the qualitative and quantitative phases identified several barriers and facilitators. The main barriers included a lack of trust in authorities, extended waiting times and distance to vaccination centres, discrimination and xenophobia, lack of identity documentation, and adverse reaction concerns. …”
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Impact of microwave processing on phytochemicals, antioxidant status, anti-nutritional factors and metabolite profile of maize flour by Alla Yaswanth Naveen Kumar, Alonkrita Chowdhury, Rajesh Kumar, Vivek Kumar Maurya, Subhasis Batabyal, Mayukh Ghosh

“…The 600-watt, 2-minute microwave treatment was identified as optimal, boosting phytochemicals and antioxidants in maize flour while minimally impacting the main metabolite profile. The outcomes of this comprehensive analysis espouse microwave technology in maize-based food processing to benefit humans as well as the animal and poultry feed industries.…”
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The IL-1B Gene Polymorphisms rs16944 and rs1143627 Contribute to an Increased Risk of Coronary Artery Lesions in Southern Chinese Children with Kawasaki Disease by Lan Yan Fu, Xiantao Qiu, Qiu Lian Deng, Ping Huang, Lei Pi, Yufen Xu, Di Che, Huazhong Zhou, Zhaoliang Lu, Yaqian Tan, Zhiyong Jiang, Li Zhang, Techang Liu, Xiaoqiong Gu

“…Kawasaki disease (KD) is a systemic form of self-limited vasculitis in children less than five years old, and the main complication is coronary artery injury. However, the etiology of KD remains unclear. …”
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AHP Approach To Developing a New Natural Toothpaste Product by Dikky Indrawan, Stevia Septiani, Galih Saputra Arista, Asep Rakhmat, Yessie W Sari, Nur A Nuzulia, Wulan T Wahyuni, Irmanida Batubara, Y. Aris Purwanto

“…Health advantages are also noteworthy, especially, herbal smells promote well-being and satisfaction. Purpose: The study main objective aimed to examine how the Analytic Hierarchy Process (AHP) was used to create a new natural toothpaste product. …”
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The agronomic mechanism of root lodging resistance and yield stability for sweet corn in response to planting density and nitrogen rates at different planting dates by Qinggan Liang, Qinggan Liang, Qinggan Liang, Qinggan Liang, Hailong Chang, Hailong Chang, Hongrong Chen, Hongrong Chen, Qingdan Wu, Qingdan Wu, Yuanxia Qin, Zhuqing Wang, Gang Wang, Xuhui Li, Weiwei Chen, Jiantao Wu, Jiantao Wu, Qinnan Wang, Jianqiang Wang, Jianqiang Wang

“…Two nitrogen (N) rates (200 kg ha-1, N200; 150 kg ha-1,N150) applied to the main plots and three planting densities (20 cm plant space, D20; 25 cm plant space, D25; and 30 cm plant space, D30; 60 cm rows space for all plots) as subplots. …”
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SARS-CoV-2 infection and antibody seroprevalence in routine surveillance patients, healthcare workers and general population in Kita region, Mali: an observational study 2020–2021... by Ulla Ashorn, Per Ashorn, Nigel Klein, Samba O Sow, Camilla Ducker, Elaine Cloutman-Green, Dagmar Alber, Fadima Cheick Haidara, Juho Luoma, Laura Adubra, Henry Badji, Fatoumata Diallo, Rikhard Ihamuotila, Owen Martell, Uma U Onwuchekwa, Oumar Samaké, Awa Traore, Kevin Wilson, Yue-Mei Fan

“…Objective To estimate the degree of SARS-CoV-2 transmission among healthcare workers (HCWs) and general population in Kita region of Mali.Design Routine surveillance in 12 health facilities, HCWs serosurvey in five health facilities and community serosurvey in 16 villages in or near Kita town, Mali.Setting Kita region, western Mali; local health centres around the central (regional) referral health centre.Participants Patients in routine surveillance, HCWs in local health centres and community members of all ages in populations associated with study health centres.Main outcome measures Seropositivity of ELISA test detecting SARS-CoV-2-specific total antibodies and real-time RT-PCR confirmed SARS-CoV-2 infection.Results From 2392 routine surveillance samples, 68 (2.8%, 95% CI: 2.2% to 3.6%) tested positive for SARS-CoV-2 by RT-PCR. …”
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Cognitive impairment at older ages among 8000 men and women living in Mexico City: a cross-sectional analyses of a prospective study by Carlos González-Carballo, Pablo Kuri-Morales, Erwin Chiquete, Mario Rojas-Russell, Rogelio Santacruz-Benitez, Raúl Ramirez-Reyes, Adrián Garcilazo-Ávila, Jaime Berumen, Eirini Trichia, Louisa Gnatiuc Friedrichs, Paulina Orellana, Carolina Ochoa-Rosales, Gary O’Donovan, Jonathan R Emberson, Roberto Tapia-Conyer, Diego Aguilar-Ramirez, Jesus Alegre-Díaz

“…In 2015–2019 about 10,000 survivors were resurveyed with identical information from the original survey and additional assessments including a cognitive assessment. The main analyses included those aged 50–89 years with complete cognitive assessment and covariate data at resurvey. …”
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Titanium nanotubes modulate immunophenotyping and cytokine secretion of T cells via IL-17A: a bioinformatic analysis and experimental validation by Jingju Yin, Jingju Yin, Jingju Yin, Jingju Yin, Yunyang Liao, Yunyang Liao, Yunyang Liao, Yunyang Liao, Shaofeng Liu, Shaofeng Liu, Shaofeng Liu, Shaofeng Liu, Bangwei Che, Hanghang Zhu, Hanghang Zhu, Bingbing Yang, Bingbing Yang, Bingbing Yang, Bingbing Yang, Bin Shi, Bin Shi

“…The proliferation and expressions of the main transcription factors and cytokines of T-cells were detected. …”
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Development and Validation of a Nomogram for Predicting Long-Term Net Adverse Clinical Events in High Bleeding Risk Patients Undergoing Percutaneous Coronary Intervention by Junyan Zhang, Zhongxiu Chen, Ran Liu, Yuxiao Li, Hongsen Zhao, Yanning Li, Minggang Zhou, Hua Wang, Chen Li, Li Rao, Yong He

“…These were then utilized to construct a prognostic prediction nomogram, including chronic kidney disease, left main stem lesion, multivessel disease, triglycerides (TG), and creatine kinase-myocardial band (CK-MB). …”
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