Path analysis of factors influencing length of stay and hospitalisation expenses for oral cancer patients in tertiary hospitals in southeastern China: a cross-sectional study by Jing Wang, Chen Chen, Xiaoying Hu, Yi Fan, Yaping Wang, Yu Qiu, Qiujiao Yang, Mingming Xu, Yanfeng Weng, Yanni Li, Lisong Lin, Fa Chen, Baochang He, Fengqiong Liu

“…Aims To investigate the associations between influencing factors with length of stay (LOS) and hospitalisation expenses in oral cancer (OC) patients, and to explore the potential pathways through which these factors influence hospitalisation expenses using path analysis.Design Cross-sectional.Setting A comprehensive tertiary hospital in southeastern China.Participants A total of 810 patients with histologically confirmed primary OC admitted to the First Affiliated Hospital of Fujian Medical University, Fujian Province, between 2015 and 2020.Main outcome measures LOS and hospitalisation expenses for OC patients.Results The median hospitalisation expenses and LOS for OC patients in southeastern China were substantial, amounting to $6330 and 29 days, respectively. …”
Get full text

Improving protein hydrolysis and digestibility in Arthrospira platensis biomass through recombinant peptidases (EC 3.4): Opportunities for monogastric animal diets by Maria P. Spínola, Mónica M. Costa, Rita S. Simões, Vânia O. Fernandes, Vânia Cardoso, Virgínia M.R. Pires, Cláudia Afonso, Carlos Cardoso, Narcisa M. Bandarra, Carlos M.G.A. Fontes, José A.M. Prates

“…The protein solubility and hydrolysis, specifically of two main protein fractions (18–26 kDa and 40–48 kDa) along with minor fractions, were analysed via 14 % sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). …”
Get full text

Nasopharyngeal carriage of Staphylococcus aureus in a rural population, Sierra Leone by Lisa Maria Kleine, Emmanuel Marx Kanu, Tobias Grebe, Desmond Mohamed Sesay, Henning Loismann, Maxwell Sesay, Tom Theiler, Viktoria Rudolf, Alexander Mellmann, Laura C. Kalkman, Martin P. Grobusch, Frieder Schaumburg

“…PVL gene was detected in 21.3 % of isolates (37/174) mainly associated with ST15 and ST152. Except for past use of antimicrobials (p = 0.019), no specific risk factors such as comorbidities including hemoglobin variants were associated with S. aureus nasopharyngeal colonization. …”
Get full text

Transcervical resection of myoma (TCRM): Part I by Peng-Hui Wang, Szu-Ting Yang, Wen-Hsun Chang, Hung-Hsien Liu, Wen-Ling Lee

“…Additionally, fertility-sparing or uterus-preservation is the main goal and becomes very popular in both physicians and patients. …”
Get full text

Winter wheat yield responses to growing degree days: Long-term trends and adaptability in major producing areas of China by Ziyang Liu, Davide Cammarano, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…This study used 40 years of data from experimental stations in China’s main winter wheat-producing areas to explore the spatiotemporal changes in GDD in the context of climate change and a linear mixed-effects regression model to elucidate the relationship between accumulated GDD at different growth stages and wheat yield. …”
Get full text

Long-Term Follow-Up, Association between CARD15/NOD2 Polymorphisms, and Clinical Disease Behavior in Crohn’s Disease Surgical Patients by Francesco Giudici, Tiziana Cavalli, Cristina Luceri, Edda Russo, Daniela Zambonin, Stefano Scaringi, Ferdinando Ficari, Marilena Fazi, Amedeo Amedei, Francesco Tonelli, Cecilia Malentacchi

“…Methods. 191 surgical CD patients were prospectively characterized both for the main single nucleotide polymorphisms of CARD15/NOD2 and for many other environmental risk factors connected with the severe disease form. …”
Get full text

The expression profile of genes associated with behavior, stress, and adult neurogenesis along the hippocampal dorsoventral axis in tame and aggressive foxes by Yu. V. Alexandrovich, E. V. Antonov, S. G. Shikhevich, A. V. Kharlamova, L. V. Meister, Y. V. Makovka, D. V. Shepeleva, R. G. Gulevich, Yu. E. Herbeck

“…These differences are mainly consistent with those found in rodents and humans. …”
Get full text

Self-Perceived Barriers to Pediatric Cancer Care in Sub-Saharan Africa: A Cross-Sectional Multinational Study by Ole Stoeter, Nikolaus C.S. Mezger, Tamara Koenig, Eric Chokunonga, Girum Tessema, Adugna Fekadu Damise, Alda Stevy Makouanzi, Esther Majaliwa, Mahine Ivanga, Bakarou Kamate, Franck Gnahatin, Sarah Nambooze, Ima-Obong A. Ekanem, Toralf Bernig, Biying Liu, Sumit Gupta, Eva Johanna Kantelhardt

“…Further expanding measures of social support for affected families should be regarded as one of the main pillars to assure access to care.…”
Get full text

Whole blood transcriptome profiles of trypanotolerant and trypanosusceptible cattle highlight a differential modulation of metabolism and immune response during infection by Trypan... by Peylhard, Moana, Berthier, David, Dayo, Guiguigbaza-Kossigan, Chantal, Isabelle, Sylla, Souleymane, Nidelet, Sabine, Dubois, Emeric, Martin, Guillaume, Sempéré, Guilhem, Flori, Laurence, Thévenon, Sophie

“…Animal African trypanosomosis, caused by blood protozoan parasites transmitted mainly by tsetse flies, represents a major constraint for millions of cattle in sub-Saharan Africa. …”
Get full text

A Morphological and Immunohistochemical Study of the Tumoral and Inflammatory Cells in Pancreatic Ductal Adenocarcinoma by Vlad Herlea, Elena Stoica Mustafa, Andreea Cristina Iorgescu, Nicolae Catalin Pechianu, Dragos Cretoiu, Maria Sajin, Simona Olimpia Dima, Catalin Vasilescu, Cezar Stroescu, Constantin Ungureanu, Traian Dumitrascu, Vladislav Brasoveanu, Minerva Ghinescu, Irinel Popescu

“…This study represents a multidisciplinary approach, and it is a result of teamwork; it presents histopathological methods of examination of this severe illness and describes only a part of the scientific effort to determine the main pathological mechanisms of this neoplasm.…”
Get full text

Revisiting ABC Transporters and Their Clinical Significance in Glioblastoma by Brandon Wee Siang Phon, Shalini Sundramurthi Chelliah, Dina El-Rabie Osman, Saatheeyavaane Bhuvanendran, Ammu Kutty Radhakrishnan, Muhamad Noor Alfarizal Kamarudin

“…ATP-binding cassette (ABC) transporters function as drug transporters and have been touted to be the main culprits in developing resistance to xenobiotic drugs in GBM. …”
Get full text

Сandidate SNP-markers of rheumatoid arthritis that can significantly alter the affinity of the TATA-binding protein for human gene promoters by I. V. Chadaeva, D. A. Rasskazov, E. B. Sharypova, I. A. Drachkova, E. A. Oshchepkova, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko, N. A. Kolchanov, V. A. Kozlov

“…That is why, RA fits the main idea of postgenomic predictive-preventive personalized medicine that is to give a chance to those who would like to reduce his/her risk of diseases by bringing his/her conditions and lifestyle in line with the data on his/her genome sequenced. …”
Get full text

Overcoming barriers to engagement and adherence to a home-based physical activity intervention for patients with heart failure: a qualitative focus group study by Guy A MacGowan, Sarah Charman, Djordje G Jakovljevic, Nduka C Okwose, Nicola O'Brien, Sophie Cassidy, David Brodie, Kristian Bailey, Leah Avery

“…Data were analysed using thematic analysis.Participants A purposive sample of 16 patients, 82% male, aged 68±7 years, with heart failure duration of 10±9 years were recruited.Intervention A 12-week behavioural intervention targeting physical activity was delivered once per week by telephone.Results Ten main themes were generated that provided a comprehensive overview of the active ingredients of the intervention in terms of engagement and adherence. …”
Get full text

Effect of botanical powders and the assassin bug, Alloeocranum biannulipes Mont. and Sign. (Hemiptera: Reduviidae) against Dinoderus porcellus Lesne (Coleoptera: Bostrichidae) infe... by Kitherian SAHAYARAJ, Antonio SINZOGAN, Manuele TAMO, Joelle TOFFA, Yêyinou Laura Estelle LOKO, Armand VODOUNNON, Innocent DJEGBE

“…Background Dinoderus porcellus Lesne (Coleoptera: Bostrichidae) is the main pest of stored dried yam chips that causes significant losses in less than 3 months. …”
Get full text

Efficacy and Safety of an Aflibercept Treat-and-Extend Regimen in Treatment-Naïve Patients with Macular Oedema Secondary to Central Retinal Vein Occlusion (CRVO): A Prospective 12-... by Jose Garcia-Arumi, Francisco Gómez-Ulla, Navea Amparo, Enrique Cervera, Alex Fonollosa, Luis Arias, Javier Araiz, Juan Donate, Marta Suárez de Figueroa, Lucia Manzanas, Jaume Crespí, Roberto Gallego

“…Intravitreal aflibercept 2 mg monthly (3 months) followed by proactive individualized dosing. Main Outcomes. Mean change in BCVA after 12 months. …”
Get full text

Harnessing genomic and bioinformatic data to broaden understanding of leukaemia across continents by Gumelar Gugun, Ulfa Mia Maria, Amukti Danang Prasetyaning, Irham Lalu Muhammad, Yuliani Sapto, Adikusuma Wirawan, Khairi Sabiah, Darmawi Darmawi, Chong Rockie, Ates Ilker, Singh Dilpreet, Chavan Aditya Ashok

“…Current management of acute leukaemia still uses chemo therapy as the main therapy but has many side effects, therefore a new approach is needed to identify genetic factors involved in leukaemia. …”
Get full text

The simulation of ELM control by the advanced divertor configuration in EAST by Y.L. Li, T.Y. Xia, Z.P. Luo, Q.Z. Yu, S.F. Mao, B. Gui, X.X. He, H.M. Qi, P.C. Xie, M.Y. Ye, the EAST team

“…Using the EFIT code, a series of plasma equilibria with different 2nd X-points and nearly fixed last closed flux surfaces (LCFSs) are generated to analyze the effects of the different magnetic configurations on ELMs. Here we mainly discuss the standard single-null (SN), snowflake plus (SF+), and snowflake minus (SF-) divertors. …”
Get full text

Prevalence and epidemiological characteristics of inmates diagnosed with infectious diseases living in a region with a high number of prisons in São Paulo state, Brazil by Charlene Troiani do Nascimento, Danilo Zangirolami Pena, Rogério Giuffrida, Fernanda Nobre Bandeira Monteiro, Francisco Assis da Silva, Edilson Ferreira Flores, Luiz Euribel Prestes-Carneiro

“…Improvements in diagnosis, mainly to reduce viral hepatitis, are crucial with benefits for inmates and the general population.…”
Get full text

Study protocol of a population-based cohort investigating Physical Activity, Sedentarism, lifestyles and Obesity in Spanish youth: the PASOS study by Susana Aznar, Camille Lassale, Santiago Felipe Gómez, Clara Homs, Julia Wärnberg, Maria Medrano, Marcela Gonzalez-Gross, Narcis Gusi, Elena Marín Cascales, Miguel González-Valeiro, Lluis Serra-Majem, Nicolás Terrados, Josep A Tur, Marta Segú, Juan Carlos Benavente-Marín, Idoia Labayen, Augusto García Zapico, Jesús Sánchez-Gómez, Fabio Jiménez-Zazo, Pedro Emilio Alcaraz, Marta Sevilla-Sanchez, Estefania Herrera-Ramos, Susana Pulgar, Maria del Mar Bibiloni, Olga Sancho, Helmut Schröder

“…Parents are asked about their educational level, time spent doing PA, diet quality, self-perceived stress, smoking habit, weight, height, their child’s birth weight and if the child was breast fed.Ethics and dissemination The study was approved by the Ethics Committee of the Fundació Sant Joan de Déu, Barcelona, Spain. Main findings of the study will be disseminated to the scientific community and to general public by media conferences, social media and a website.Trial registration number ISRCTN34251612.…”
Get full text

Screening of <em>FecLL</em> prolific allele of the <em>B4GALNT2</em> gene in Algerian sheep populations by Assia Hadjazi, Fatima Zahra Belharfi, Fatima Zohra Mahammi, Stéphane Fabre, Semir Bechir Suheil Gaouar, Nacera Tabet-Aoul

“… Background: Research on the main genes controlling prolificacy in sheep, also known as fecundity genes (Fec genes), has highlighted the mechanisms involved in ewe fertility and the genetic improvement of prolificacy. …”
Get full text