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32241
Fatigue life prediction of asphalt binders under variable loading levels based on dissipated pseudo-strain energy
Published 2025-07-01“…However, the conventional model makes it difficult to recognize the significant dependency of the fatigue life of viscoelastic asphalt binders on the interaction and sequence produced by variable loading levels. The main objective of this study is to propose a fatigue life prediction method for asphalt binders considering such two factors. …”
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32242
Prevalence of Pulmonary Embolism in COVID-19 Positive Critically Ill Children
Published 2025-01-01“…None. MEASUREMENTS AND MAIN RESULTS:. Among the PE-positive subgroups, from January 2020 to December 2021, 78 patients (14%) had an acute COVID-19 infection. …”
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32243
Microbial dynamics of acute pancreatitis: integrating culture, sequencing, and bile impact on bacterial populations and gaseous metabolites
Published 2025-02-01“…We observed that Escherichia coli 33 isolated from stool exhibited active gaseous metabolite production (mainly hydrogen).ConclusionsThe abundant production of hydrogen may substantially impact enzymatic processes, inducing specific alterations in disulfide bonds and trypsin inactivation. …”
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32244
Endoscopic band ligation alone and combined with clipping for colonic diverticular bleeding: A retrospective comparative study
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32245
Ultrasound-guided percutaneous microwave ablation of primary hyperthyroidism: security and efficacy analysis
Published 2024-12-01“…Pre- and postablative examinations, including grayscale ultrasound, contrast-enhanced ultrasound (CEUS), laboratory examination, antithyroid drug (ATD) dosage, and quality of life (QoL) assessment via Thyroid-Specific Patient-Reported Outcome Short-Form (ThyPRO-39), were analyzed retrospectively. The main ultrasound follow-up times were 1, 3, 6, and 12 months after ablation. …”
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32246
Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2
Published 2025-01-01“…Moreover, the direct engulfment, a main avenue in microglia that may be responsible for Cd-induced synaptic damages and regulated by Nrf2, was specifically studied in vivo and in vitro, along with underlying specific mechanisms. …”
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32247
Multi-platform diagnostic strategy and biosecurity as basis of contagious agalactia control programs in endemic areas
Published 2025-01-01“…Abstract Background Control strategies against contagious agalactia (CA), considered one of the most important diseases affecting small ruminants in countries surrounding the Mediterranean, are mainly based on traditional strategies considered suboptimal such as the use of inactivated vaccines and antibiotics. …”
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32248
Development of the algal pigment-based salinity transfer function for lakes on the Tibetan Plateau and evaluation of the quantitative reconstruction
Published 2025-01-01“…Comparison with other paleoclimatic and meteorological records revealed that the lake salinity was mainly influenced by climate-mediated changes in regional precipitation and effective moisture. …”
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32249
Structure and dynamics analysis of brain functional hypernetworks based on the null models
Published 2025-01-01“…The results showed that there were differences in the level of dependence between the features of interest. Node degree is the main dependency attribute for multiple metrics. Hyperedge degree, node degree-dependent redundancy coefficient, and hyperedge degree-dependent redundancy coefficient are partial dependency attributes for some metrics. …”
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32250
ZEB1 as a marker of metastasis in thyroid carcinomas: review of literature and own data
Published 2024-11-01“…Growth factors activate intracellular signaling pathways, which in turn induce several repressors of E-cadherin gene transcription, such as Snail, Slug, zinc finger E-box binding homeobox 1 (ZEB1), ZEB2, Twist, TBX-2, and SIX. ZEB1 is the main EMT-TF of the ZEB family and is associated with cellular plasticity, dissemination, and the switch from a dormant to proliferative phenotype at distant metastatic sites and is a determinant of poorer clinical prognosis in most human cancers. …”
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32251
Did the resurgence of childhood lower respiratory infections offset the initial benefit of COVID-19-related non-pharmaceutical interventions in children? A time-series analysis
Published 2025-02-01“…All hospitalisations from January 2015 to March 2023 and all ambulatory visits for LRTI from a network of 110 paediatricians from June 2017 to March 2023 were included. The main outcome was the monthly incidence of children hospitalised for LRTI per 100,000 over time, assessed by a seasonally adjusted quasi-Poisson regression model. …”
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32252
6‐Nitrodopamine potentiates catecholamine‐induced contractions of human isolated vas deferens
Published 2025-02-01“…Abstract 6‐Nitrodopamine (6‐ND) is the main catecholamine released from human isolated vas deferens and the adrenergic nervous system is known to play a major role in the contractions of the epididymal portion of the vas deferens. …”
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32253
Studying the Humoral Response against SARS-CoV-2 in Cuban COVID-19 Recovered Patients
Published 2024-01-01“…Our results suggest that disease severity, and not demographic features such as age, sex, and skin color, is the main determinant of the magnitude and neutralizing ability of the anti-RBD antibody response. …”
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32254
Yiqi Fumai Lyophilized injection protects cardiac contractility in a rat model of heart failure with reduced ejection fraction by modulating SERCA2
Published 2025-02-01“…Results: Twenty-five compounds, mainly ginsenosides, were identified in YQFM. In rats with HFrEF, treatment with YQFM or metoprolol prevents deterioration of cardiac contractility. …”
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32255
Nicotine is associated with smoking dependence and vascular inflammation through cotinine: A mediation analysis
Published 2024-01-01“…Introduction The main alkaloid component in cigarettes is nicotine. …”
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32256
Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway
Published 2025-01-01“…IntroductionUlcerative colitis (UC) is a global gastrointestinal disease, which is mainly caused by both dysfunctional epithelial barrier and inflammation response. …”
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32257
Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men
Published 2021-01-01“…Although obesity and insulin resistance are associated with an increased incidence of cardiovascular disease, whether they lead to abnormal expression of circulating SHBG or its interaction with androgen signaling remains to be elucidated. SHBG is produced mainly in the liver, but it can also be expressed in several tissues including the brain, fat tissue, and myocardium. …”
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32258
Inhibition of Endothelial–Mesenchymal Transition Mediated by Activin Receptor Type IIA Attenuates Valvular Injury Induced by Group A Streptococcus in Lewis Rats
Published 2025-01-01“…Background: Rheumatic heart disease (RHD), which is caused mainly by Group A Streptococcus, leads to fibrotic damage to heart valves. …”
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32259
Characterization of an IncR Plasmid with Two Copies of ISCR-Linked qnrB6 from ST968 Klebsiella pneumoniae
Published 2020-01-01“…The IncR plasmids were derived from different bacterial genera or species, mainly Klebsiella pneumoniae (70.82%, 182/257), Escherichia coli (11.28%, 29/257), Enterobacter cloacae (7.00%, 18/257), and Citrobacter freundii (3.50%, 9/257). …”
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32260
DeepGolf: A fine-grained perception framework for golf course distribution in the real world based on multi-source remote sensing data
Published 2025-02-01“…DeepGolf is structured into three main modules: geographic query, detection, and fine extraction. …”
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