Improving the accUracy of Referrals to the emerGency departmEnt of patieNts with chesT pain using the modified HEART score in Emergency Medical Transport (URGENT 2.0): protocol for... by Joan G Meeder, Frits H M Van Osch, Robert T A Willemsen, Braim M Rahel, Lisa D S Frenk, Cees B de Vos, Fabiana G Prestigiacomo, Marcel J W Janssen, Arnoud W van 't Hof

“…The results of this trial will be disseminated in one main paper and in additional papers with subgroup analyses.Trial registration ClinicalTrials.gov, NCT04904107.…”
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Correlation between mitral annular plane systolic excursion (MAPSE) at different degrees of ejection fraction in patients with diabetes mellitus by Muhammad Rido, Khalid Saleh, A. Makbul Aman, Syakib Bakri, Haerani Rasyid, Andi Alfian Zainuddin

“…This research revealed that mitral annular plane systolic excursion (MAPSE) is significantly associated with ejection fraction (EF) in individuals with diabetes mellitus (DM), mainly when EF is either well-maintained or diminished.…”
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Geochemistry and Genesis of Oil and Gas Seeps in the Junggar Basin, NW China: Implications for Hybrid Petroleum Systems by Jingkun Zhang, Jian Cao, Yan Wang, Jun Li, Guang Hu, Ni Zhou, Tianming Shi

“…Type 4 oil seeps, with Cretaceous source rocks, occur in the Anjihai and Huoerguosi areas within the middle segment of the southern basin. Type 5 oil seeps mainly have Paleogene source rocks with a minor contribution from Jurassic rocks and occur in the Wusu and Dushanzi areas in the western segment of the southern basin with the single-type gas seeps. …”
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A positive experience in applying the biolistic approach to potato varieties Aksor and Nevskiy by N. P. Malakhova, Y. A. Skiba, G. A. Iskakova, D. A. Naizabayeva, B. K. Tezekbaeva, G. A. Ismagulova, E. R. Maltseva

“…The method of biological ballistics (biolistic transformation, genetic bombardment) of plants is one of the most modern methods used for direct gene transfer into plant cells. The main advantages of this method include the ability to simultaneously incorporate several target genes into the plant genome, carry out transfer without unnecessary agrobacterial parts and plasmid DNA sequences, and the short time needed to produce transgenic cells. …”
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Investigation of Anti-Friction Properties of MoS₂ and SiO₂ Nanolubricants Based on the Friction Pairs of Inconel 718 Superalloy and YG6 Carbide by Lijie Ma, Fengnan Li, Shijie Ba, Zunyan Ma, Xinhui Mao, Qigao Feng, Kang Yang

“…The energy spectrum test results show that the action mechanism of the MoS₂ nano-additive is the adsorption film effect and mending effect of nanoparticles, while the main action mechanism of the SiO₂ nano-additive should be the polishing effect and rolling effect of nanoparticles.…”
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Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients by Katharina Bell, Vanessa M. Beutgen, Stefan Nickels, Katrin Lorenz, Yvonne Scheller, Hisham Elbaz, Tunde Peto, Katharina A. Ponto, Andreas Schulz, Philipp S. Wild, Thomas Münzel, Karl J. Lackner, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Franz H. Grus, Alexander K. Schuster

“…We performed a nested case-control study (1 : 4) within the Gutenberg Health Study (GHS), a population-based, prospective cohort study in the Rhine-Main Region of Germany including 15,010 participants. …”
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Cancer Cell‐Derived Exosomal miR‐500a‐3p Modulates Hepatic Stellate Cell Activation and the Immunosuppressive Microenvironment by Yu Zhang, Xin Li, Huiyan Chen, Jiawei Li, Xiaohuan Guo, Yilin Fang, Linjie Chen, Kaiqiang Li, Yi Zhang, Fei Kong, Aodong Chen, Jianxin Lyu, Wei Zhang, Zhen Wang

“…Abstract Hepatocellular carcinoma (HCC) mainly depends on liver fibrosis/cirrhosis, which is regulated by tumor cells and the tumor microenvironment (TME), and is a crucial factor in tumor progression. …”
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Pleural metastases from differentiated thyroid cancer: clinical features and long-term outcomes by Mengyue Liu, Juan Tang, Nan Sun, Chuang Xi, Chentian Shen, Song Hongjun, Quanyong Luo, Xianzhao Deng, Zhongling Qiu

“…Radioiodine (131I) therapy has been the main treatment for postoperative metastasis and recurrence of DTC. …”
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Ecotoxicity of lanthanides to Daphnia magna: insights from elemental behavior and speciation in a standardized test medium by Vignati, Davide A.L., Martin, Loïc A., Poirier, Laurence, Zalouk-Vergnoux, Aurore, Fouque, Chantal, Bojic, Clément, Hissler, Christophe, Cossu-Leguille, Carole

“…Thermodynamic speciation calculations confirm the possible formation of insoluble species, mainly LN carbonates. However, the corresponding theoretical solubility limits do not fully agree with measured concentrations at the end of the tests. …”
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Modeling extracellular matrix through histo-molecular gradient in NSCLC for clinical decisions by Camila Machado Baldavira, Tabatha Gutierrez Prieto, Juliana Machado-Rugolo, Juliana Machado-Rugolo, Jurandir Tomaz de Miranda, Lizandre Keren Ramos da Silveira, Ana Paula Pereira Velosa, Walcy Rosolia Teodoro, Alexandre Ab’Saber, Teresa Takagaki, Vera Luiza Capelozzi

“…Lung cancer still represents a global health problem, being the main type of tumor responsible for cancer deaths. …”
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Influence of Sweetness and Ethanol Content on Mead Acceptability by Gomes Teresa, Dias Teresa, Cadavez Vasco, Verdial João, Morais Jorge Sá, Ramalhosa Elsa, Estevinho Letícia M.

“…Nevertheless, to date few studies have been developed on factors that may influence mead quality. The main objective of this work was to study the influence of sweetness and ethanol content on mead acceptability. …”
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An AI-Based Digital Scanner for <i>Varroa destructor</i> Detection in Beekeeping by Daniela Scutaru, Simone Bergonzoli, Corrado Costa, Simona Violino, Cecilia Costa, Sergio Albertazzi, Vittorio Capano, Marko M. Kostić, Antonio Scarfone

“…Detecting the parasite and defining the intervention thresholds for effective treatment is a difficult and time-consuming task; different detection methods exist, but they are mainly based on human eye observations, resulting in low accuracy. …”
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Post-marketing safety surveillance for the recombinant zoster vaccine (Shingrix), vaccine adverse event reporting system, United States, October 2017–April 2024 by Yamin Shu, Wenxin Cheng, Xucheng He, Liu Huang, Wei Chen, Qilin Zhang

“…Among reports with age or sex reported, individuals were mainly 50–79 years (71.2 %) and females (63.1 %). …”
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The Influence of Reservoir Composition on the Pore Structure of Continental Shale: A Case Study from the Qingshankou Formation in the Sanzhao Sag of Northern Songliao Basin, NE Chi... by Jianguo Yang, Liu Wang, Shichao Li, Cheng Zuo, Fei Xiao, Yuchu Chen, Yulai Yao, Longhui Bai

“…The organic matter pore is less developed, mainly composed of intragranular pores and crack pores of organic matter. …”
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Colorectal Cancer and Polyps in Diverticulosis Patients: A 10-Year Retrospective Study in 13680 Patients by Fadi Abu Baker, Jesus Alonso Z'cruz De La Garza, Amir Mari, Abdel-Rauf Zeina, Amani Bishara, Oren Gal, Yael Kopelman

“…Diverticulosis was located mainly to the sigmoid and left colon (94.4%). The CRC diagnosis rate was lower in the diverticulosis group (2% vs. 4.5%, odds ratio=0.472, P<0.001, and 95%CI=0.382‐0.584). …”
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Deep-Learning-Driven Insights into Nitrogen Leaching for Sustainable Land Use and Agricultural Practices by Caixia Hu, Jie Li, Yaxu Pang, Lan Luo, Fang Liu, Wenhao Wu, Yan Xu, Houyu Li, Bingcang Tan, Guilong Zhang

“…Analyses of the feature importance and SHAP values in the optimal XGBoost model identified soil organic matter, chemical nitrogen fertilizer input, and water input (including rainfall and irrigation) as the main indicators of nitrate leaching loss. The ML-based modeling method developed overcomes the difficulty of the determination of the functional relationship between nitrate loss intensity and its influencing factors, providing a data-driven solution for estimating nitrate–nitrogen loss in farmlands in North China and strengthening sustainable agricultural practices.…”
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Urinary I-FABP, L-FABP, TFF-3, and SAA Can Diagnose and Predict the Disease Course in Necrotizing Enterocolitis at the Early Stage of Disease by Stepan Coufal, Alena Kokesova, Helena Tlaskalova-Hogenova, Barbora Frybova, Jiri Snajdauf, Michal Rygl, Miloslav Kverka

“…Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease affecting mainly preterm newborns. It is characterized by unexpected onset and rapid progression with specific diagnostic signs as pneumatosis intestinalis or gas in the portal vein appearing later in the course of the disease. …”
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Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial by Jianyi Wei, Shupeng Liu, Yuexiang Bian, Lei Li, Biyun Qian, Zixuan Shen, Yan Zhang, Adila Abuduaini, Fuchen Dong, Xin Zhang, Jinhui Li, Yongpei Yu, Weituo Zhang, Jun Wang, Wei Zhai, Qixiang Song, Yu Zheng, Weihua Pan, Lanlan Yu, Qimin Zhan, Ning Zhang, Junhua Zheng, Shuming Pan, Chen Yao, Hai Li

“…Patients were randomized to receive 120 mg/day of CEP, 60 mg/day CEP or placebo for 5 days. Main outcome was the time from randomization to negative nasopharyngeal swab and safety. …”
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Functional Genetic Variant in ATG5 Gene Promoter in Acute Myocardial Infarction by Yexin Zhang, Xiaohui He, Jiarui Li, Wentao Yang, Yinghua Cui, Shuchao Pang, Haihua Wang, Bo Yan

“…Coronary artery disease (CAD) including acute myocardial infarction (AMI) is an inflammatory and metabolic disease mainly caused by atherosclerosis. Dysfunctional autophagy has been associated with abnormal lipid metabolism and inflammation. …”
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Types and cost of wellness services provided by a neighborhood-based academic nursing center by Hae-Ra Han, Hae-Ra Han, Yoon-Jae Lee, Yoon-Jae Lee, Jennifer J. Lee, Chun-An Sun, Ophelia Dapaah-Gyimah, Patty Wilson, Catherine Ling, Eric Slade, Eric Slade

“…The Johns Hopkins School of Nursing’s Center for Community Programs, Innovation, and Scholarship (COMPASS Center) provides free wellness services, aiming to address healthcare disparities in the neighborhoods.ObjectiveTo delineate the types and cost of wellness services provided by the COMPASS Center.MethodsThe study employed a secondary analysis design, utilizing Qualtrics surveys to assess wellness service data from 2017 to 2022 at two main program sites—Wald center and House of Ruth, Maryland.ResultsThe analysis covered 2,194 encounters (826 at Wald center and 1,368 at House of Ruth, Maryland). …”
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