Plant Coping with Cold Stress: Molecular and Physiological Adaptive Mechanisms with Future Perspectives by Yan Feng, Zengqiang Li, Xiangjun Kong, Aziz Khan, Najeeb Ullah, Xin Zhang

“…This review summarizes the mechanisms of how plants respond to cold stress, covering four main signal transduction pathways, including the abscisic acid (ABA) signal transduction pathway, Ca²⁺ signal transduction pathway, ROS signal transduction pathway, and mitogen-activated protein kinase (MAPK/MPK) cascade pathway. …”
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From MRI to FEM: an automated pipeline for biomechanical simulations of vertebrae and intervertebral discs by Kati Nispel, Kati Nispel, Tanja Lerchl, Gabriel Gruber, Hendrik Moeller, Robert Graf, Veit Senner, Jan S. Kirschke, Jan S. Kirschke

“…Ten vertebra and seven IVD FE simulations failed to converge.DiscussionThe main goal of our work was to automate the modeling and FEM simulation of both patient-specific vertebrae and intervertebral discs with shared-node surfaces directly from MRI segmentations. …”
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Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB by Yongzhan Sun, Quan Zou, Huizheng Yu, Xiaoping Yi, Xudan Dou, Yu Yang, Zhiheng Liu, Hong Yang, Junya Jia, Yupeng Chen, Shao-Kai Sun, Lirong Zhang

“…However, previous studies have mainly focused on acute ROS-related diseases, leaving a knowledge gap regarding their potential in chronic conditions. …”
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Cerebral hemodynamics and oxygen metabolism in patients with milder and severe forms of sickle cell disease and thalassemia by Liza Afzali‐Hashemi, Koen P. A. Baas, Anouk Schrantee, Erfan Nur, Chau Vu, Soyoung Choi, Silvie Suriany, John C. Wood, Aart J. Nederveen, Bart J. Biemond

“…Abstract Silent cerebral infarcts (SCIs) are present in patients with sickle cell disease (SCD) and thalassemia, but the pathophysiology of SCIs is not fully understood. Previous studies mainly focused on cerebral hemodynamics and oxygen metabolism in patients with severe SCD (HbSS/HbSβ°) but not in milder forms of SCD (HbSC/HbSβ+) and thalassemia despite the high prevalence of SCIs in these patients. …”
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Clonal dissemination of an NDM-2-producing Acinetobacter baumannii ST103 clone resulting in an outbreak in an intensive care unit of a Lebanese tertiary care hospital by Tania Nawfal Dagher, Linda Hadjadj, Fadi Bittar, Fadi Fenianos, Elias Abdo, Jean-Marc Rolain, Charbel Al-Bayssari

“…Results: Polymerase chain reaction and multilocus sequence typing results suggested the presence of two different periods: period 1 (November 2018 to February 2019), where 15 CRAB isolates were collected harbouring the blaOXA-23 and blaOXA-24 genes mainly and belonging to several clones; and period 2 (March to May 2019), considered an outbreak period where 17 carbapenem-resistant isolates were isolated, harbouring mostly the blaNDM-2 gene, never previously described in Lebanon and belonging to ST103. …”
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Quality-by-Design Principles Applied to the Establishment of a Pharmaceutical Quality Control Laboratory in a Resource-Limited Setting: The Lab Water by Sultan Suleman, Sileshi Belew, Dereje Kebebe, Markos Duguma, Henok Teshome, Gemmechu Hasen, null Evelien Wynendaele, Luc Duchateau, Bart De Spiegeleer

“…It is already frequently applied in the pharmaceutical industry mainly in the development of pharmaceutical products and analytical methods but is not well established in the setup of facilities like quality control (QC) laboratory (lab). …”
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Anti-Inflammatory Effects of Concentrated Ethanol Extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cells by Lulli Daniela, Potapovich Alla, Riccardo Maurelli, Dellambra Elena, Pressi Giovanna, Kostyuk Vladimir, Dal Toso Roberto, De Luca Chiara, Pastore Saveria, Korkina Liudmila

“…Comparison of the dose-dependent inhibition of chemokine (IL-8, IP-10, MCP-1) and growth factor (GM-CSF) release from PHK activated by TNFα + IFNγ showed that leontopodic acid was mainly responsible for the inhibitory effects of ECC55. …”
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Practices of Breast Self-Examination and Associated Factors among Female Debre Berhan University Students by Kalayu Birhane, Miskir Alemayehu, Belayneh Anawte, Gebru Gebremariyam, Ruth Daniel, Semeneh Addis, Teshome Worke, Abdurrahman Mohammed, Wassie Negash

“…Lack of knowledge on how to perform BSE was cited as the main reason for not practicing BSE. Knowing how to perform, when to perform, and position to perform BSE and having a perception that BSE is important and useful to detect breast cancer were significant predictors of practices of BSE. …”
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The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome by Tiantian Gu, Mingcai Duan, Li Chen, Yong Tian, Wenwu Xu, Tao Zeng, Lizhi Lu

“…GO and KEGG analysis mainly enriched in glycine, serine, and threonine metabolism, tyrosine metabolism, and pyruvate metabolism. …”
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Bp-13 PLA2: Purification and Neuromuscular Activity of a New Asp49 Toxin Isolated from Bothrops pauloensis Snake Venom by Georgina Sucasaca-Monzón, Priscila Randazzo-Moura, Thalita Rocha, Frank Denis Torres-Huaco, Augusto Vilca-Quispe, Luis Alberto Ponce-Soto, Sérgio Marangoni, Maria Alice da Cruz-Höfling, Léa Rodrigues-Simioni

“…In biventer cervicis preparations, Bp-13 induced irreversible twitch-tension blockade and the KCl evoked contracture was partially, but significantly, inhibited (P>0.05). The main effect of this new Asp49 PLA2 of Bothrops pauloensis venom is on muscle fiber sarcolemma, with avian preparation being less responsive than rodent preparation. …”
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Pixel-wise navigation line extraction of cross-growth-stage seedlings in complex sugarcane fields and extension to corn and rice by Hongwei Li, Hongwei Li, Xindong Lai, Yongmei Mo, Deqiang He, Tao Wu, Tao Wu

“…Nevertheless, in field management of crop seedlings, numerous available studies involving navigation line extraction mainly focused on specific growth stages of specific crop seedlings so far, lacking a generalizable algorithm for addressing challenges under complex cross-growth-stage seedling conditions. …”
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In Vitro Evaluation of the Antifungal Activity of Ghassoul-Based Formulations with Oregano and Thyme Essential Oils against Penicillium sp. by Hamid Ziyat, Mohammed Naciri Bennani, Safae Allaoui, Jamal Houssaini, Hasna Nait M’barek, Soukaina Arif, Hassan Hajjaj

“…Their chemical compositions were analyzed by the GC-MS technique. The main constituents of thyme EO were thymol (67.13%), ρ-cymene (4.85%), Z-caryophyllene (1.77%), and γ-terpinene (2.74%). …”
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RGB Composition Obtained by a UAV in the Monitoring of Sugarcane Row Gaps Using the Biophysical Index by Camila G. B. de Melo, Mário M. Rolim, Roberta Q. Cavalcanti, Marcos V. da Silva, Ana Lúcia B. Candeias, Pabrício M. O. Lopes, Pedro F. S. Ortiz, Renato P. de Lima

“…Sugarcane crops have a long cycle with successive harvests before re-planting, and row gaps are one of the main problems associated with the yield. The objective of this study was to establish an alternative methodology for measuring the planting and regrowth of sugarcane rows using UAV (Unmanned Aerial Vehicle) images and to compare it with manual measurements. …”
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Survival after Locoregional Treatments for Hepatocellular Carcinoma: A Cohort Study in Real-World Patients by Simona Signoriello, Annalisa Annunziata, Nicola Lama, Giuseppe Signoriello, Paolo Chiodini, Ilario De Sio, Bruno Daniele, Giovanni G. Di Costanzo, Fulvio Calise, Graziano Olivieri, Vincenzo Castaldo, Rosario Lanzetta, Guido Piai, Giampiero Marone, Mario Visconti, Mario Fusco, Massimo Di Maio, Francesco Perrone, Ciro Gallo, Giovanni B. Gaeta

“…Overall survival (OS) was the unique endpoint. Three main comparisons were planned: RFA versus PEI, surgical resection versus RFA/PEI (combined), TACE/TAE versus RFA/PEI (combined). …”
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Feather hydrolysate as a promising nitrogenârich fertilizer for greenhouse lettuce cultivation by Lisiane Sobucki, Rodrigo Ferraz Ramos, Elci Gubiani, Gustavo Brunetto, Douglas Rodrigo Kaiser, Daniel Joner Daroit

“…Feathers, possessing a substantial amount of organic nitrogen, are mainly converted into feather meal (FM) through the hydrothermal process; however, microbial conversion into feather hydrolysates (FH) is increasingly being focused on. …”
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Perceived barriers to reaching equity in effective access to diagnosis and treatment for women with breast cancer in Chile by Carla Campaña, Báltica Cabieses, Alexandra Obach, Francisca Vezzani

“…From the determinants of health model, a woman from the public health system, with low income, under 30 or over 40, and residing in a different region from the metropolitan region faces more barriers to access to an effective healthcare. The main barriers were for the high centralisation of healthcare in Chile, not integrated health system network, misinformation to the patient, and non-humanized healthcare. …”
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The antibacterial activity of clove Syzygium aromaticum extract and its effects on the survival rate of hybrid grouper Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂ infected with... by Inem Ode, Sukenda, Widanarni, Dinamella Wahjuningrum, Munti Yuhana, Mia Setiawati

“… Vibrio alginolyticus which becomes the main cause of vibriosis disease in grouper culture and causes great economic loss in Asian aquaculture industries. …”
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Effects of Tremella fuciformis -Derived Polysaccharides with Different Molecular Weight on D-Galactose-Induced Aging of Mice by Donghui Luo, Xiaofei Liu, Jingjing Guan, Guili Jang, Yanglin Hua, Xinfei Zhang, Xiaofei Xu

“…In the present study, a purified TFP, named HM, mainly composed of mannose, fucose, xylose, and glucose in a molar ratio of 4.14:0.98:0.81:0.62, was obtained from the fruiting body of T. fuciformis . …”
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Promoting Computational Access to Digital Collections in the Nordic and Baltic Countries: An Icelandic Use Case by Gustavo Candela, Olga Holownia, Max Odsbjerg, Mirjam Cuper, Nele Gabriëls, Katrine Hofmann, Edward J. Gray, Sally Chambers, Mahendra Mahey

“…The intended audience is Digital Humanities researchers and GLAM professionals interested in exploring the computational reuse of digital collections. The main contributions of this work are: (a) a framework for creating a collection of Jupyter Notebooks in the GLAM domain, (b) the reproducible code and examples of use, and (c) the results obtained after its application. …”
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A tannic acid-based intumescent flame retardant for improving flame retardancy of epoxy composites by Xiaosui Chen, Yaoting Ma, Shuzheng Liu, Aiqing Zhang, Wei Liu, Shengchao Huang

“…Analyses from the condensed char and pyrolysis gases indicated that the improved flame retardancy was mainly attributed to the cooperation of the free-radical quenching effect of P-containing radicals and phenoxy radicals working in stages (derived from DOPO and TA respectively) and the physical barrier effect caused by the highly graphited, intumescent and porous char layer (reinforced by P- and Si-containing cross-linked structures). …”
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