Integration of ATAC-seq and RNA-seq reveals signal regulation during post-molt and inter-molt stages in muscle of Eriocheir sinensis by Bin Wang, Bin Wang, Jingjing Li, Mingzhi Zhang, Mingzhi Zhang, Anqi Li, Zhentao Song, Zhentao Song, Zhen He, Zhen He, Ruiqi Zhang, Ruiqi Zhang, Tong Hao, Tong Hao, Jinsheng Sun, Jinsheng Sun

“…GO enrichment analysis revealed that the up-regulated genes are largely associated with protein phosphorylation and phosphorus metabolism, while the down-regulated genes are mainly involved in DNA metabolism, transcription, cell adhesion, and G protein-coupled receptor (GPCR) signaling pathway. …”
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Effect of Prolonged-Release Pirfenidone on Renal Function in Septic Acute Kidney Injury Patients: A Double-Blind Placebo-Controlled Clinical Trial by Jonathan S. Chávez-Iñiguez, Jorge L. Poo, Miguel Ibarra-Estrada, Leonel García-Benavides, Guillermo Navarro-Blackaller, Cynthia Cervantes-Sánchez, Eduardo Nungaray-Pacheco, Ramón Medina-González, Juan Armendariz-Borunda, Guillermo García-García

“…The mean age was 54 (17 ± SD) years, and 47% were male. The main site of infection was the lung (39.8%), septic shock was present in 39.1% of the cases, and the mean SOFA score was 8.8 points. 28 patients received PFD 1,200 mg, 30 patients received PFD 600 mg, and 30 patients received placebo. …”
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Environmental innovations as factor of development of petrochemical industry in Russia by A. I. Shinkevich, S. S. Kudryavtseva, Yu. N. Khakimullin, M. I. Farakhov

“…Result: the article shows that among the main types of environmental innovations introduced in the petrochemical industry are the reduction of material and energy costs, the reduction of carbon dioxide emissions, the reduction of the negative impact on the environment, the replacement of petrochemical materials with safer ones, recycling of petrochemical waste; it is revealed that the primary factor influencing the intensification of the introduction of environmental innovations in the petrochemical industry is the result of the introduction of eco-innovations at industrial petrochemical enterprises, which is reduced from the intensity of costs for environmental innovations in this industry. …”
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Effects of Base Materials (α-Alumina and/or γ-Alumina) on Volatile Organic Compounds (VOCs)-Sensing Properties of Adsorption/Combustion-Type Microsensors by Takeo Hyodo, Yuma Matsuura, Genki Inao, Takahiko Sasahara, Yasuhiro Shimizu, Taro Ueda

“…On the other hand, the static responses to both ethanol and toluene, which arise from their catalytic combustion at elevated temperatures (450 °C), mainly increased with an increase in the addition of α-Al₂O₃ in the 5 wt% Pt-loaded aluminas. …”
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Palliative care practice of a patient with envolizumab-induced exfoliative dermatitis complicated with schizophrenia (1例免疫治疗致剥脱性皮炎合并精神分裂症患者的安宁疗护实践)... by ZHANG Lufen (张芦芬), MENG Weifen (孟卫芬), LIU Wei (刘伟), YUE Jingyan (岳静燕)

“…The palliative care practice mainly included controlling the symptoms of exfoliative-induced dermatitis to improve comfort, finding psychological problems and mental disorders and then giving timely intervention, improving the strength of social support, paying attention to patients' spiritual needs and providing spiritual comfort, etc. …”
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Pharmaceuticals as emerging pollutants: Implications for water resource management in Malaysia by Asvinidevi Arumugam, Khai Ern Lee, Pei Yuen Ng, Aida Soraya Shamsuddin, Aziemah Zulkifli, Thian Lai Goh

“…Geographically, Selangor state accounted for the majority of studies (n = 29), with limited research in other states, reflecting a notable gap in national monitoring efforts. One of the main contributors to pharmaceutical occurrence in water bodies is household disposal. …”
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Enhancing Campus Mobility: Simulated Multi-Objective Optimization of Electric Vehicle Sharing Systems Within an Intelligent Transportation System Frameworks by Omar S. Aba Hussen, Shaiful J. Hashim, Nasri Sulaiman Member, S.A.R. Alhaddad, Bassam Y. Ribbfors, Masanobu Umeda, Keiichi Katamine

“…This research optimizes an electric vehicle (EV) sharing system for a university campus, focusing on different demand patterns and peak times within an Intelligent Transportation System (ITS) framework. The main objectives are to reduce the number of unserved demands and operational costs. …”
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Artificial intelligence driven cyberattack detection system using integration of deep belief network with convolution neural network on industrial IoT by Mahmoud Ragab, Mohammed Basheri, Nasser N. Albogami, Alanoud Subahi, Omar A. Abdulkader, Hashem Alaidaros, Hassan Mousa, Abdullah AL-Malaise AL-Ghamdi

“…Therefore, this study designs a Next–Generation Cybersecurity Attack Detection using an ensemble deep learning model (NGCAD-EDLM) technique in the IIoT environment. The main cause of the NGCAD-EDLM technique is the automatic recognition of cyber-attacks. …”
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Effects of Floral Characters on the Pollination Biology and Breeding System of <i>Iris setosa</i> (Iridaceae): A Cold-Tolerant Ornamental Species from Jilin Province by Xiyue Zhang, Ruoqi Liu, Lifei Chen, Tianhao Pei, Yu Gao, Xi Lu, Yunwei Zhou

“…The sexual reproduction system was mainly outcrossing, with some self-compatibility and a need for pollinators. …”
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Proactive and Integrated Management and Empowerment in Parkinson’s Disease: Designing a New Model of Care by Emma Tenison, Agnes Smink, Sabi Redwood, Sirwan Darweesh, Hazel Cottle, Angelika van Halteren, Pieter van den Haak, Ruth Hamlin, Jan Ypinga, Bastiaan R. Bloem, Yoav Ben-Shlomo, Marten Munneke, Emily Henderson

“…We propose a new model, termed PRIME Parkinson (Proactive and Integrated Management and Empowerment in Parkinson’s Disease), which is designed to manage problems proactively, deliver integrated, multidisciplinary care, and empower patients and their carers. It has five main components: (1) personalised care management, (2) education and empowerment of patients and carers, (3) empowerment of healthcare professionals, (4) a population health approach, and (5) support of the previous four components by patient- and professional-friendly technology. …”
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A Laboratory Approach Considering Salinity to Investigate Archie’s Parameters in Deep Shale: A Case Study in Longmaxi Formation, Southern Sichuan by Yanran Li, Xiangui Liu, Changhong Cai, Zhiming Hu, Bo Wu, Ying Mu, Xianggang Duan, Qingxiu Zhang, Shuti Zeng, Jingshu Guo, Zhijin Pu

“…It was concluded that the complicated pore structure and high porosity mainly associated with clay mineral may trigger the increased cementation factor. …”
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The Society of Orthodox Parishes of Petrograd and its Province (1920–1922): the Experience of Sobornost under Persecution by Goltsov, Nikita V.

“…In addition to the general issues that have been considered to a greater or lesser extent in historiography (the circumstances of the Society’s emergence, its purpose, structure, and main activities), in this article the author explores the founders’ ecclesiological views, finding that their key category for conceiving of church life was sobornost. …”
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Combining ability of spring barley varieties in the direct diallel cross system by E. V. Kompanets, M. R. Kozachenko, N. I. Vasko, A. G. Naumov, P. N. Solonechniy, S. I. Sviatchenko

“…GCA variances exceeded SCA variances in ‘Zvershennya’ in 2014–2015 for the trait “1000-grain weight” (GCA – 4.20 and 4.03, respectively; SCA – 3.78 and 3.84, respectively), therefore, it is determined mainly by additive gene effects. Strong and weak SCA effects were observed for plant productivity (grain weight) and its structural components (productive tillering, grain number per spike, 1000-grain weight). …”
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Structural and functional connectivity coupling as an imaging marker for bone metastasis pain in lung cancer patients by Jiahui Zheng, Chengfang Wang, Xiaoyu Zhou, Yu Tang, Lin Tang, Yong Tan, Jing Zhang, Hong Yu, Jiuquan Zhang, Daihong Liu

“…Notably, hyper-couplings related to bone metastasis pain were present in several brain regions, mainly involving the default mode network, frontoparietal network, salience network, and limbic system. …”
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Value of C-Reactive Protein in Predicting Left Ventricular Remodelling in Patients with a First ST-Segment Elevation Myocardial Infarction by Iwona Swiatkiewicz, Marek Kozinski, Przemyslaw Magielski, Tomasz Fabiszak, Adam Sukiennik, Eliano Pio Navarese, Grazyna Odrowaz-Sypniewska, Jacek Kubica

“…CRP concentration rose during the first 24 h, mainly in LVR group. The prevalence of LVR was higher in patients from the highest quartile of CRP concentrations at 24 h as compared to those from any other quartile (odds ratio (OR) 3.48, 95% confidence interval (95% CI) 1.76–6.88). …”
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Acute therapeutic effects and pathophysiology of eosinophilic granulomatosis with polyangiitis neuropathy by Fumitaka Shimizu, Mariko Oishi, Toshihiko Maeda, Yukio Takeshita, Hideaki Nishihara, Ryota Sato, Takashi Kanda, Masayuki Nakamori, Michiaki Koga, Miwako Fujisawa, Yuki Mizumoto, Nanami Yamanaka, Takashi Nawata, Tatsuya Okafuji, Susumu Fujikawa, Kinya Matsuo, Joe Nemoto, Masaya Honda

“…Intrafascicular oedema was found in 95% of all patients.Discussion Our results suggest three pathological pathways: (1) ischaemic peripheral nerve due to vasculitis mainly in ANCA-positive cases, (2) direct infiltration and degranulation of eosinophils in ANCA-negative cases and (3) progression of axonal ischaemia due to intrafascicular oedema in both cases. …”
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Observation and Simulation of Wind Speed and Wind Power Density over Bac Lieu Region by Hiep Van Nguyen, Pham Xuan Thanh, Nguyen Duc Nam, Nguyen Xuan Anh, Pham Le Khuong, Hoang Hai Son, Nguyen Tien Manh, Pham Chi Cong

“…Wind speeds over the eastern coastal region of Southern Vietnam are much stronger in winter than in summer due to two main reasons, including (1) stronger large-scale wind speed in winter than in summer and (2) funnel effect creating a local maximum wind speed over the nearshore ocean which then transports high-momentum air inland in winter.…”
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Population Dynamics of <i>Cypripedium macranthos</i> Sw. and Its Interactions with Environmental Factors in the Changbai Mountains by Lifei Chen, Wei Liu, Nan Jiang, Yiting Xiao, Yuze Shan, Shizhuo Wang, Sulei Wu, Qi Wang, Jiahui Yu, Yuqing Zhang, Xi Lu, Hongyu Qiao

“…In conclusion, crown density, soil alkali-hydrolysed nitrogen, and available soil potassium concentration were the main environmental factors influencing the morphological and functional form of <i>C. macranthos</i>. …”
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Effect of Genetic Predisposition on Blood Lipid Traits Using Cumulative Risk Assessment in the Korean Population by Min Jin Go, Joo-Yeon Hwang, Dong-Joon Kim, Hye-Ja Lee, Han Byul Jang, Kyung-Hee Park, Jihyun Song, Jong-Young Lee

“…Dyslipidemia, mainly characterized by high triglyceride (TG) and low high-density lipoprotein cholesterol (HDL-C) levels, is an important etiological factor in the development of cardiovascular disease (CVD). …”
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Etiology and Prognosis of Cardiogenic Shock in a Secondary Center without Surgical Back-Up by Laurent Bonello, Marc Laine, Etienne Puymirat, Victoria Ceccaldi, Mélanie Gaubert, Franck Paganelli, Pr Franck Thuny, Thibaut Dabry, Guillaume Schurtz, Clement Delmas, Julien Mancini, Gilles Lemesle

“…Data regarding CS etiologies and their prognosis are limited and mainly derived from tertiary referral centers. Aims. …”
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