Comparative transcriptome analysis on candidate genes involved in lipid biosynthesis of developing kernels for three walnut cultivars in Xinjiang by Wenqiang Wang, Hao Wen, Qiang Jin, Wenjun Yu, Gen Li, Minyu Wu, Hongjin Bai, Lirong Shen, Cuiyun Wu

“…Finally, 5 important transcription factors including WRI1, ABI3, FUS3, PKL and VAL1 were identified, and their main regulatory genes might contain ACCase, KASⅡ, LACS, FAD3 and LPAAT which were determined through correlation analysis of expression levels for 27 walnut samples. …”
Get full text

The influence of calfhood diarrhea and pneumonia on preweaning growth and reproductive performance of Holstein heifers by Mely T. Olivera, Jesús Mellado, José E. García, Juan A. Encina, Perpetuo Álvarez, Ulises Macías-Cruz, Leonel Avendaño, Miguel Mellado

“…Calves´ birth and weaning weights were recorded, and subsequent reproductive performance was registered. Main results: The preweaning daily gain in calves suffering diarrhea (573 ± 12 g/d), pneumonia (557 ± 12 g/d), and comorbidity of these diseases (520 ± 13 g/d) were lower (p<0.05) than healthy calves (594 ± 11 g/d). …”
Get full text

Long-Term Assessment of Soil Salinization Patterns in the Yellow River Delta Using Landsat Imagery from 2003 to 2021 by Yu Fu, Pengyu Wang, Wengeng Cao, Shiqian Fu, Juanjuan Zhang, Xiangzhi Li, Jiju Guo, Zhiquan Huang, Xidong Chen

“…The salinized area increased from 538.4 km² in 2003 to 761.5 km² in 2021, particularly between 2009 and 2015, with a 47.95% increase. The main factors influencing salinization in the YRD were distance from the Bohai Sea, seasonal average potential evapotranspiration, and seasonal average normalized vegetation index, with interaction-driven effects being stronger than single-factor effects. …”
Get full text

A zebrafish model of Ifih1-driven Aicardi–Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients by Beatriz Bernal-Bermúdez, Beatriz Bernal-Bermúdez, Beatriz Bernal-Bermúdez, Alicia Martínez-López, Alicia Martínez-López, Francisco J. Martínez-Morcillo, Francisco J. Martínez-Morcillo, Francisco J. Martínez-Morcillo, Sylwia D. Tyrkalska, Sylwia D. Tyrkalska, Sylwia D. Tyrkalska, Teresa Martínez-Menchón, Teresa Martínez-Menchón, Teresa Martínez-Menchón, Pablo Mesa-del-Castillo, Pablo Mesa-del-Castillo, Pablo Mesa-del-Castillo, María L. Cayuela, María L. Cayuela, María L. Cayuela, Victoriano Mulero, Victoriano Mulero, Victoriano Mulero, Diana García-Moreno, Diana García-Moreno

“…Type I interferonopathies are a heterogenic group of rare diseases associated with an increase in type I interferon (IFN). The main challenge for the study of Type I interferonopathies is the lack of a well-founded animal model to better characterize the phenotype as well as to perform fast and large drug screenings to offer the best treatment options. …”
Get full text

Enhanced breast cancer cell targeting: RGD integrin ligand potentiates RWQWRWQWR’s cytotoxicity and inhibits migration by Andrea Barragán-Cárdenas, Daniel Castellar-Almonacid, Yerly Vargas-Casanova, Claudia Parra-Giraldo, Adriana Umaña-Pérez, Joel López-Meza, Zuly Rivera-Monroy, Javier García-Castañeda

“…On the other hand, addition of the RGD sequence to the palindromic peptide in the N-terminal end resulted in a greater cytotoxic effect against cell lines derived from the three mainly diagnosed breast cancer molecular subtypes. …”
Get full text

AI in academia: How do social influence, self-efficacy, and integrity influence researchers' use of AI models? by Benicio Gonzalo Acosta-Enriquez, Marco Arbulu Ballesteros, César Robin Vilcapoma Pérez, Olger Huamaní Jordan, Joseph Anibal Martin Vergara, Rafael Martel Acosta, Carmen Graciela Arbulu Perez Vargas, Julie Catherine Arbulú Castillo

“…This investigation pursued two main objectives: first, to identify the variables that condition the implementation of AI models in research activities, and second, to analyze how perceived ethical considerations and academic integrity influence their adoption. …”
Get full text

The Impact of Cooking on Antioxidant and Enzyme Activities in Ruichang Yam Polyphenols by Haoping Liu, Hua Zhang, Mengting Geng, Dingxin Shi, Dongsheng Liu, Yanxiao Jiao, Zhiqiang Lei, You Peng

“…TPC and TFC of soluble conjugated polyphenols were the main phenolic compounds in Ruichang yam. Compared with uncooked yam, cooking times of 80 min and 40 min increased the TPC and TFC of multiple types of polyphenols, while cooking reduced the TPC and TFC of AHP (acid-hydrolyzed soluble conjugated polyphenols). …”
Get full text

The use of urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin for diagnosis of hepato-renal syndrome in advanced cirrhotic patients by Mohamed Adel Abd Elaziz, Asmaa Mustafa Gouda Elewa, Dina Zaki Mohamed Zaki Abdel Hamid, Nohier Essam Soliman Ahmed Hassan, Éva Csongrádi, Emad Hamdy Hamouda Mohammed, Mohammed Abdel Gawad

“…Here, we present a cross-sectional study to explore the sensitivity and specificity of other markers as urinary KIM-1 and NGAL for cases of HRS.Methods Cross-sectional study was conducted on 88 patients who were admitted to Alexandria main university hospital. Enrolled patients were divided in two groups; group 1: patients with advanced liver cirrhosis (child B and C) who have normal kidney functions while group 2: patients who developed HRS. …”
Get full text

Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases by Mingyu Wu, Ke Li, Jiabin Wu, Xianyi Ding, Xiaotong Ma, Wenhong Wang, Weihua Xiao

“…As a kind of monomer in Chinese medicine with multitarget pharmacological effects, G-Rg1 can provide significant therapeutic benefits in the alleviation of alcoholic liver disease, nonalcoholic fatty liver disease, liver fibrosis, viral hepatitis, etc., which mainly rely on the inhibition of apoptosis, strengthening endogenous anti-inflammatory and antioxidant mechanisms, activation of immune responses and regulation of efflux transport signals, to improve pathological changes in the liver caused by lipid deposition, inflammation, oxidative stress, accumulation of hepatotoxic product, etc. …”
Get full text

The role of 1-Deoxysphingolipids and Polyamines in the pathogenesis of placental syndrome by Filiz Yarsilikal Guleroglu, Ali Cetin, Goknil Pelin Coskun, Meltem Caliskan, Fulya Karaduman, Can Bilginer, Resat Misirlioglu, Sinem Tekin, Merve Nur Al, Tugce Caklili, Yusuf Tutar

“…Abstract Background Placental syndrome, mainly composed of preeclampsia and fetal growth restriction, has an impact on the health of mother and baby dyads. …”
Get full text

Identification of circRNA/miRNA/mRNA regulatory network involving (+)-catechin ameliorates diabetic nephropathy mice by Chao Chen, Dina Zhu, Shuai Zhang, Wensheng Zhang

“…(+)-Catechin (CE) is mainly found in green and black tea and has many biological effects, such as anti-inflammatory, anti-cancer, anti-viral effects, protecting human organs, especially the kidney. …”
Get full text

Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells by Hongzhuan Zhou, Huanhuan Zhang, Xia Su, Fuzhou Xu, Bing Xiao, Jin Zhang, Qi Qi, Lulu Lin, Kaidi Cui, Qinqin Li, Songping Li, Bing Yang

“…The results showed that CPV VP2 protein participated mainly in cell metabolism, cell biosynthesis, protein folding and various signal transduction processes. …”
Get full text

Long non-coding RNAs modulate glutathione metabolism gene expression and tolerance to Pb stress in root tissue of endophyte-infected rice seedling by He-Fei Sun, Xin-Nan Wang, Ya-Nan Li, Lan-Lan Wang, Yue-Ying Li, Lian-Ju Ma, Xue-Mei Li

“…DEmRNAs in ceRNA network were mainly participated in carbohydrate metabolic process, peroxidase activity and phenylpropanoid biosynthesis. …”
Get full text

Transcriptome Analysis Revealed the Molecular Mechanism of Acetic Acid Increasing <i>Monascus</i> Pigment Production in <i>Monascus ruber</i> CICC41233 by Yan Wang, Weiwei Wu, Xiaoshu Wu, Weiyu Li, Jingjing Cui, Chuannan Long

“…The transcriptomics data showed that the differentially expressed genes between <i>M. ruber</i> with acetic acid and without acetic acid were mainly involved in starch and sucrose metabolism, glycolysis/gluconeogenesis, pyruvate metabolism, TCA cycle, and oxidative phosphorylation, and that these differentially expressed genes were not involved in amino acid metabolism. …”
Get full text

Can growth in captivity alter the calcaneal microanatomy of a wild ungulate? by Cottereau, Romain, Ortiz, Katia, Locatelli, Yann, Houssaye, Alexandra, Cucchi, Thomas

“…Results provide evidence for compressive and tensile forces as the main elements affecting the variation in the cortical thickness along the calcaneus. …”
Get full text

Effect of a virtual walking and exercise-based intervention on muscle strength and activation in people with incomplete spinal cord injury by Sara Mollà-Casanova, Elena Muñoz-Gómez, Noemí Moreno-Segura, Marta Inglés, Marta Aguilar-Rodríguez, Núria Sempere-Rubio, Pilar Serra-Añó

“…Strength and muscle activation of main lower limb muscles were assessed. EI group exhibited a general strength increase after intervention (T2), (16.31–34.72 N), and maintained this improvement up to 1-month-follow-up (T3) for hip abduction and extension movements. …”
Get full text

Performance and stability analysis of all-perovskite tandem photovoltaics in light-driven electrochemical water splitting by Junke Wang, Bruno Branco, Willemijn H. M. Remmerswaal, Shuaifeng Hu, Nick R. M. Schipper, Valerio Zardetto, Laura Bellini, Nicolas Daub, Martijn M. Wienk, Atsushi Wakamiya, Henry J. Snaith, René A. J. Janssen

“…We find that the performance loss is mainly due to the degradation of the photovoltaic component. …”
Get full text

Structure and origin of Tuvan gene pool according to autosome SNP and Y-chromosome haplogroups by V. A. Stepanov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, I. Yu. Khitrinskaya, V. N. Kharkov

“…Tuvans are one of the most compactly living peoples of Southern Siberia, settled mainly in the territory of Tuva. The gene pool of the Tuvans is quite isolated, due to endogamy and a very low frequency of interethnic marriages. …”
Get full text

Implication of Galaxy-scale Negative Feedback by One of the Most Powerful Multiphase Outflows in a Hyperluminous Infrared Galaxy at Intermediate Redshift by Xiaoyang Chen, Masayuki Akiyama, Kohei Ichikawa, Yoshiki Toba, Toshihiro Kawaguchi, Takuma Izumi, Toshiki Saito, Daisuke Iono, Masatoshi Imanishi, Kianhong Lee, Hiroshi Nagai, Hirofumi Noda, Abdurro’uf, Mitsuru Kokubo, Naoki Matsumoto

“…Powerful galactic outflows driven by active galactic nuclei (AGNs) are commonly considered as one of the main mechanisms to regulate star formation in massive galaxies. …”
Get full text

Cardiovascular Risk and Metabolic Syndrome Characteristics in Patients with Nonfunctional Pituitary Macroadenoma by Guadalupe Vargas-Ortega, Baldomero González-Virla, Lourdes Balcázar-Hernández, Oriana Nieto-Guzmán, Ana Pamela Garrido-Mendoza, Marco Antonio Flores-Maya, Victoria Mendoza-Zubieta

“…Patients and Methods. 71 patients with NFPMA treated according to a preestablished multimodal protocol. Main Outcome Measures. Prevalence of diabetes, hypertension, high cholesterol, obesity, and cardiovascular risk and its relationship with the clinical and biochemical characteristics. …”
Get full text