Hailey-Hailey disease successfully treated with naloxone: 2 case reports and Review of the literature on efficacy of opioid receptor antagonist in Hailey-Hailey disease patients by Junyou Zheng, Zhimin Duan, Beilei Xu, Hao Song, Jianbing Wu, Fang Fang, Nan Sheng, Chengrang Li

“…Clinically, HHD is characterized by flaccid vesicles, blisters, erosions, fissures, and maceration mainly in intertriginous regions. Some patients remain refractory to conventional treatments. …”
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Chip Design of PTP Time Synchronization for Industrial IoT by Yee-Shao Chen, Yuan-Sun Chu, da-Wei Lo, Yen-Ting Chiang, Ting-Chao Hou

“…After a detailed study of the IEEE 1588 protocol, this paper found that the main sources of time errors are frequency changes caused by the temperature characteristics and aging of the crystal oscillator, the uncertainty of network protocol stacking delay, and the queuing delay caused by packets. …”
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Evaluation of Inflammation-Related Proteins in Multiple Sclerosis Disease with Relapses and Remissions by Nisa Hocaoğlu, Nur Damla Korkmaz, Birsen Elibol, Zehra Cemre Karakayalı, Şule Terzioğlu-Uşak, Azize Esra Gürsoy

“…Conclusion: Our findings showed that anti-inflammatory NLRX1 protein can be considered as a strong biomarker in the diagnosis and treatment of MS, where neuroinflammation is the main cause.…”
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A review of the application and efficacy of tuina therapy in the treatment of neonatal jaundice (推拿疗法在新生儿黄疸治疗中的应用现状) by YANG Juandong (杨娟东), PANG Lihong (庞立宏), LIU Ling (刘凌), ZHANG Xiaoxia (张小霞), LING Jizu (凌继祖)

“…Neonatal jaundice is a common condition in the neonatal period, caused mainly by abnormally elevated levels of bilirubin in the body. …”
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A systematic review of Machine Learning and Deep Learning approaches in Mexico: challenges and opportunities by José Luis Uc Castillo, Ana Elizabeth Marín Celestino, Diego Armando Martínez Cruz, José Tuxpan Vargas, José Alfredo Ramos Leal, Janete Morán Ramírez

“…A total of 15 subject areas were identified, where Social Sciences and Medicine were the main application areas. It observed that Artificial Neural Networks (ANN) models were preferred, probably due to their capability to learn and model non-linear and complex relationships in addition to other popular models such as Random Forest (RF) and Support Vector Machines (SVM). …”
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Transcriptome analysis reveals effects of ethynylestradiol and bisphenol A on multiple endocrine and metabolic pathways in the pituitary and liver of female Atlantic cod (Gadus mor... by Fekadu Yadetie, Xiaokang Zhang, Anna Reboa, Gwenaëlle Samantha Chloe Noally, Mariann Eilertsen, Mitchell Stewart Fleming, Jon Vidar Helvik, Inge Jonassen, Anders Goksøyr, Odd André Karlsen

“…IntroductionThe pituitary and liver are among the main sites of action of estrogens in fish. Years of research has shown that xenoestrogens can interfere with functions of estrogens. …”
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Lactobacillus plantarum J26 alleviates alcohol-induced oxidative liver injury by regulating the Nrf2 signaling pathway by Hongxuan Li, Shasha Cheng, Yuhong Wang, Yilin Sun, Jiaxin Zhang, Mingshuang Sun, Chaoxin Man, Yu Zhang, Yujun Jiang

“…Oxidative stress is one of the main ways to cause alcohol-induced liver injury, and alcoholic liver disease (ALD) has been a common health problem worldwide. …”
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The influence of macroscopic pedestrian structures on train boarding efficiency by Rabia I. Kodapanakkal, Caspar A.S. Pouw, Antal Haans, Jaap Ham, Gunter Bombaerts, Alessandro Corbetta, Andrej Dameski, Andreas Spahn, Federico Toschi

“…However, current research on train boarding behavior is limited in scope and mainly focuses on how group level variables such as number of boarders/deboarders influence train boarding efficiency. …”
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Evaluation of Consumers' Aspects on Organic Farming Products by Regions by Mustafa Aslan, Volkan Burucu, Filiz Pezikoğlu, Duygu Aktürk, Bülent Tarım, Sunay Demir, Ayten Aşkın Kılınç, Murat Doğu, Başak Aydın

“…The main purposes of this study were to analyze the attitude and behavior of the consumers regarding to purchase of the organic food, the socio-economic comparison of the consumers consuming and non-consuming or-ganic food and to determine the organic food consumption in consideration of different regions. …”
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Computer Based Correlation of the Texture of P63 Expressed Nuclei with Histological Tumour Grade, in Laryngeal Carcinomas by Konstantinos Ninos, Spiros Kostopoulos, Ioannis Kalatzis, Panagiota Ravazoula, George Sakelaropoulos, George Panayiotakis, George Economou, Dionisis Cavouras

“…Considering that P63 is mainly nuclear stain, a possible correlation between the texture of P63-stained nuclei and the tumor’s grade could be of value to diagnosis, since this may be related to biologic information imprinted as texture on P63 expressed nuclei. …”
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Prediction and Risk Factors for Prognosis of Cirrhotic Patients with Hepatic Encephalopathy by Ying Peng, Qinglin Wei, Yun Liu, Zhenyu Wu, Hongjia Zhang, Hongbo Wu, Jin Chai

“…Acute-on-chronic liver failure (ACLF) mainly occurs in patients with chronic liver diseases and often presents with HE. …”
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Exploring Employee Perspectives on Workplace Technology: Usage, Roles, and Implications for Satisfaction and Performance by Andreea Barbu, Mirona Ana Maria Ichimov, Iustina Cristina Costea-Marcu, Gheorghe Militaru, Dana Corina Deselnicu, Georgiana Moiceanu

“…Since technology is a pillar of each business field, the aim of this study is to explore employees’ perspectives on the use of technology at work, analyzing its main roles within the company, the benefits it provides from the employees’ viewpoint and its implications for satisfaction and performance. …”
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Influenza A virus hemagglutinin: from classical fusion inhibitors to proteolysis targeting chimera-based strategies in antiviral drug discovery by Francisco Javier Hermoso-Pinilla, Aitor Valdivia, María-José Camarasa, Tiziana Ginex, Francisco Javier Luque

“…Drug discovery studies mainly rely on preventing the recognition of sialic acid units by the receptor binding site in the globular head (GH) domain, or the conformational rearrangement required for the fusion of viral and cell membranes. …”
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Intestinal microbiota shifts by dietary intervention during extreme heat summer episodes in farmed gilthead sea bream (Sparus aurata) by R. Domingo-Bretón, S. Cools, F. Moroni, A. Belenguer, J.A. Calduch-Giner, E. Croes, P.G. Holhorea, F. Naya-Català, H. Boon, J. Pérez-Sánchez

“…Gut microbiota analysis clearly evidenced the increased abundance of bacteria of Spirochaetota phylum, mainly represented by the genus Brevinema. This microbiota shift was not driven by environmental colonization as this bacteria genus remained residual in water samples with the increase of temperature. …”
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Diabetes and gut microbiome by Kateřina Olša Fliegerová, Tiziana Maria Mahayri, Tiziana Maria Mahayri, Hana Sechovcová, Hana Sechovcová, Chahrazed Mekadim, Jakub Mrázek, Radka Jarošíková, Radka Jarošíková, Michal Dubský, Vladimíra Fejfarová, Vladimíra Fejfarová

“…The number of people suffering from this metabolic disease is constantly rising and although the incidence is heterogeneous depending on region, country, economic situation, lifestyle, diet and level of medical care, it is increasing worldwide, especially among youths and children, mainly due to lifestyle and environmental changes. …”
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Identifying Optimal Variables to Predict Soil Organic Carbon in Sandy, Saline, and Black Soil Regions: Remote Sensing, Terrain, or Climate Factors? by Liping Wang, Huanjun Liu, Xiang Wang, Xiaofeng Xu, Liyuan He, Chong Luo, Yong Li, Xinle Zhang, Deqiang Zang, Shufeng Zheng, Xiaodan Mei

“…Our results indicated that (1) climate factors, particularly mean annual precipitation and mean annual temperature, were the most effective predictors in SOC mapping across sandy, saline, and black soil regions, as indicated by their significant contribution to RF model performance (R² > 0.63); (2) followed by climate factors, the Transformed Vegetation Index (TVI) was consistently identified as the most influential variable for SOC prediction among spectral indexes in all three regions; (3) a local regression method based on RF models showed good performance compared to a global model; (4) desertification and salinization were the main reasons for the spatial differences in AH and DM&LD, respectively. …”
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TIM‐4 increases the proportion of CD4+CD25+FOXP3+ regulatory T cells in the pancreatic ductal adenocarcinoma microenvironment by inhibiting IL‐6 secretion by Ziyao Wang, Zerong Xie, Yu Mou, Ruiman Geng, Chen Chen, Nengwen Ke

“…Results In PDAC, TIM‐4 is mainly expressed in tumor cells and negatively correlated with patient prognosis. …”
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Shear Performance of Vertical Joints in Wind Turbine Concrete Towers with Different Interface Processes by Yang Zhou, Ertong Hao, Yudong Ran, Hai Cao, Yane Li, Jike Tan

“…At present, the splicing of tower vertical joints mainly uses epoxy resin filling and arc bolt connections. …”
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Evaluation of the Influence of Sensor Geometry and Physical Parameters on Impedance-Based Structural Health Monitoring by L.V. Palomino, K.M. Tsuruta, J.R.V. Mour Jr, D.A. Radea, V. Steffen Jr., D.J. Inman

“…Structural Health Monitoring (SHM) is the process of damage identification in mechanical structures that encompasses four main phases: damage detection, damage localization, damage extent evaluation and prognosis of residual life. …”
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The nonlinear viscoelasticity and its asymmetry of UV-cured resin under large amplitude oscillatory axial (LAOA) loading by Qiang Zhang, Yangguang Xu, Rui Xiao, Xiangyu Li

“…In this work, a typical UV-cured resin mainly used for 3D printing is chosen to investigate the nonlinear viscoelasticity and its asymmetry under LAOA loading. …”
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