Maraviroc/cisplatin combination inhibits gastric cancer tumoroid growth and improves mice survival by Bárbara Mora-Lagos, María Elena Reyes, Lorena Lobos-Gonzalez, Matías del Campo, Kurt Buchegger, Louise Zanella, Ismael Riquelme, Carmen Gloria Ili, Priscilla Brebi

“…The mRNA levels of C-C Motif Chemokine Ligand 5 (CCL5), the main ligand for CCR5, decreased significantly in cells treated with the MVC/CDDP combination. …”
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The design and rationale of the cardiac REHABilitation to improve metabolic health in Hypertrophic CardioMyopathy (REHAB-HCM) Study by Matthew Cheung, Nathaniel Moulson, Jinelle C. Gelinas, Ali Daraei, Sarah M. Bradwell, Carolyn Taylor, Neil D. Eves, Graeme J. Koelwyn, Thomas M. Roston

“…Intervention: A structured 3-month CR program with 6 months extended follow-up of physical activity levels. Main outcome measures: Feasibility (e.g., attendance), safety (e.g., major adverse events and exercise-related harms), and efficacy pertaining to long term improvements in physical activity levels, metabolic health, cardiorespiratory fitness, quality of life, and systemic and cellular markers of inflammation. …”
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Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway by Song Yang, Lei Yao, Xiaolong Wang, Hao Sun, Chaogang Du, Chengpeng Song, Jingyu Fu, Yongjun Wu, Hongwu Huang, Chuansi Wang, Yongsen Wang, Yixiang Xie

“…Multidrug resistance is the main cause of tumor recurrence and metastasis. Therefore, it is urgent to explore the mechanism and treatment of drug resistance of tumor cells. …”
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Niches and community stability of dominant herbaceous species in the forest and creek ecotone of Dehang Geopark by LONG Ziyu, WANG Zhicheng, ZHAO Rui, LIU Bing, CHEN Gongxi

“…This indicates that the interspecific competition among dominant species in the herbaceous communities of the forest and creek ecotone is weak, and there is not a high degree of similarity in the demand for environmental resources. (2) The overall and interspecific associations of the herbaceous plants in the three streams are mainly characterized by non-significant negative connections, with relatively low interspecific connectivity, and are mostly independently distributed. (3) The community is currently in an unstable state, and the succession and development of the herbaceous community are influenced by both internal and external factors of the community. …”
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Zinc oxide nanoparticles foliar use and arbuscular mycorrhiza inoculation retrieved salinity tolerance in Dracocephalum moldavica L. by modulating growth responses and essential oi... by Zahra Ghaffari Yaichi, Mohammad Bagher Hassanpouraghdam, Farzad Rasouli, Mohammad Ali Aazami, Lamia Vojodi Mehrabani, Samaneh Fathpour Jabbari, Mohammad Asadi, Ezatollah Esfandiari, Silvia Jimenez-Becker

“…Electrolyte leakage increased under salt stress, while mycorrhizal inoculation compensated for the trait. The main essential oil constituents were geranyl acetate, nerol, geranial, geraniol, viridiflorol, hexadecane, humulene, and germacrene D. …”
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Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study by Esat Kivanc Kaya, Burcin Halacli, Goksel Guven, Mehmet Yildirim, Asir Eren Seven, Emin Gemcioglu, Meltem Simsek, Begum Erdemir Sullu, Recep Civan Yuksel, Ahmet Safa Kaynar, Aliye Esmaoglu, Banu Kilicaslan, Seda Banu Akinci, Kursat Gundogan, Ebru Ortac Ersoy, Jordi Rello, Arzu Topeli, On behalf of the Turkish Intensive Care Studies-Network (TRICS-Net)

“…Abstract Background Scarce evidence is available on the epidemiology of microbiologically proven clinical infections in patients admitted to the intensive care unit (ICU) after a great earthquake. The main aim of this study was to assess clinical infections and microbiological features in patients admitted to the ICU following the 2023 earthquake in the southeastern region of Türkiye with a focus on the timing of culture positivity during their ICU stay. …”
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Aedes Aegypti mosquito’s breeding grounds characterization in Abreus municipality. 2016-2022 by Lisbeth Fundora Filgueiras, Jorge Enrique Rodríguez León, Esther Yarinely Hernández Dieguez, Niuvys Valera Rodríguez, Julian Sobral Rey, Idalmis Valero Valero

“…The largest number of outbreaks was detected in the Abreus’ neighborhood (165) and Juraguá (102); found mainly in yards (85.5 %) and low tanks (55.5 %). The larval phase in IV stage predominated (82.3 %).…”
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Employing the Coupled EUHFORIA‐OpenGGCM Model to Predict CME Geoeffectiveness by Anwesha Maharana, W. Douglas Cramer, Evangelia Samara, Camilla Scolini, Joachim Raeder, Stefaan Poedts

“…We further employ the dynamic time warping (DTW) technique to assess the model performance in predicting Dst. The main highlight of this study is to use EUHFORIA simulated time series to predict the Dst and auroral indices 1–2 days in advance, as compared to using the observed solar wind data at L1, which only provides predictions 1–2 hr before the actual impact.…”
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Optical Imaging Biomarkers of Drug-Induced Vascular Injury by Shu-An Lin MS, Donna L. Suresch, Brett Connolly, Gebre Mesfin, Raymond J. Gonzalez, Manishkumar R. Patel, Diane Shevell, Timothy Johnson, Bohumil Bednar

“…Flow cytometry of digested arteries revealed myeloid cells as a main source of MMPSense signal. Immunohistochemical analysis further identified elevated MMP-9 expression within arterial walls and surrounding tissue of treated animals. …”
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Decellularized Liver Matrices for Expanding the Donor Pool—An Evaluation of Existing Protocols and Future Trends by Marcin Morawski, Maciej Krasnodębski, Jakub Rochoń, Hubert Kubiszewski, Michał Marzęcki, Dominik Topyła, Kacper Murat, Mikołaj Staszewski, Jacek Szczytko, Marek Maleszewski, Michał Grąt

“…However, the removal of the cells causes varying degrees of matrix damage, that can affect cell seeding and future organ performance. The main objective of this review is to present the existing techniques of producing decellularized livers, with an emphasis on the assessment and definition of acellularity. …”
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CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis by Meijun Zhu, Bo-Ya Du, Yan-Qiu Tan, Yang Yang, Yang Zhang, Yong-Fei Wang

“…The loss-of-function mutants cpk1-1, cpk1-2, cngc5-1 cngc6-2 cngc9-1 (shrh1/short root hair 1), and cpk1 shrh1 show similar RH phenotypes, including shorter RHs, more RH branching, and dramatically attenuated cytosolic Ca2+ gradients at RH tips. The main CPK1-target sites are identified as Ser20, Ser27, and Ser26 for CNGC5/6/9, respectively, and the corresponding alanine substitution mutants fail to rescue RH growth in shrh1 and cpk1-1, while phospho-mimic versions restore the cytosolic Ca2+ gradient at RH apex and rescue the RH phenotypes in the same Arabidopsis mutants. …”
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KaRhab: an international online registry for cardiac rhabdomyomas by Vera-Maria Herrmann, Maria Arelin, Caroline G. Bergner, Julia Herrmann, Paula Janz, Henriette Kiep, Annika Mueller, Steffen Syrbe, Robert Wagner, Bardo Wannenmacher, Nadine Wolf, Michael Weidenbach, Vincent Strehlow

“…The evaluation of this paper is intended to provide a brief overview of the cohort that we have been able to include so far. Our findings mainly confirm the previous knowledge on cardiac RHM. …”
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Modeling of Shoulder–Elbow Movement with Exponential Parameter Identification During Walking Gaits for Healthy Subjects and Patients with Parkinson’s Disease by Luca Pietrosanti, Giovanni Saggio, Martina Patera, Antonio Suppa, Franco Giannini, Cristiano Maria Verrelli

“…Conclusions: The same dynamic model is actually able to capture the main features of the upper limb movement of both (healthy and pathological) walking subjects, with its parameters, in turn, characterizing the nature and progress of the pathology.…”
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Female sex is associated with short-term mortality in coronary artery bypass grafting patients: A propensity-matched analysis by Mostafa Abbas, Thomas Morland, Rohit Sharma, Jeffrey Shuhaiber, H. Lester Kirchner, Yasser El-Manzalawy

“…Background: Females undergoing coronary artery bypass grafting (CABG) surgery have been reported to be at increased risk of postoperative mortality and comorbidity. Our main objective is to evaluate the impact of female sex on 30-day mortality after isolated CABG surgery. …”
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Palliative Care in Congenital Syndrome of the Zika Virus Associated with Hospitalization and Emergency Consultation: Palliative Care and Congenital Syndrome of Zika by Aline Maria de Oliveira Rocha, Maria Julia Gonçalves de Mello, Juliane Roberta Dias Torres, Natalia de Oliveira Valença, Alessandra Costa de Azevedo Maia, Nara Vasconcelos Cavalcanti

“…Results. 145 patients were followed up at the specialized outpatient clinic, 92 (63.5%) were consulted at least once in the emergency room, and 49% had already been hospitalized, with the main reason being neurological causes, while 24.1% had never required any emergency visit or hospitalization. …”
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High β-sitosterol-D-glucoside content in sweet potato varieties and its anti-breast cancer potential through multiple metastasis-associated signals by Jinyin Zhang, Lu Huang, Xiang Tang, Miao Pan, Xiaoli Ye, Xuegang Li, Hang Ma

“…Gene ontology and network analysis showed that regulatory proteins were mainly associated with epithelial-mesenchymal transition (EMT), myogenesis, cholesterol homeostasis, oxidative phosphorylation and reactive oxygen pathways, while Vimentin, NDUF, VDAC1, PPP2CA and SNx9 were the most significant 5 node degree genes. …”
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Drying Kinetics and Changes of Total Phenolic Content, Antioxidant Activity and Color Parameters of Mango and Avocado Pulp in Refractance Window Drying by Thi-Van-Linh Nguyen, Quoc-Duy Nguyen, Phuoc-Bao-Duy Nguyen

“…Results showed that in refractance window drying, the evaporation process rapidly occurred, mainly in the falling-rate period with undetectable the constant-rate period. …”
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Diversity of bacterial symbionts associated with the tropical plant bug Monalonion velezangeli (Hemiptera: Miridae) revealed by high-throughput 16S-rRNA sequencing by Navarro-Escalante, Lucio, Benavides, Pablo, Acevedo, Flor E.

“…In most Hemiptera insects, bacterial symbionts offer mainly nutritional, defensive, and reproductive roles in addition to promoting the adaptive radiation of several hemipteran phytophagous lineages. …”
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Sub-2W tunable laser based on silicon photonics power amplifier by Neetesh Singh, Jan Lorenzen, Muharrem Kilinc, Kai Wang, Milan Sinobad, Henry Francis, Jose Carreira, Michael Geiselmann, Umit Demirbas, Mikhail Pergament, Sonia M. Garcia-Blanco, Franz X. Kärtner

“…Integrated photonics, however, is usually considered not suitable for high-power applications mainly due to its small size which limits the energy storage capacity and, therefore, the output power. …”
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Fatty Acid Composition, Phospholipid Molecules, and Bioactivities of Lipids of the Mud Crab Scylla paramamosain by Thi Phuong Lan Nguyen, Van Tuyen Anh Nguyen, Thi Thanh Trung Do, Trung Nguyen Quang, Quoc Long Pham, Tat Thanh Le

“…Notably, phospholipids were made of fatty acids with C16 : 0; C18 : 0; C20 : 4; C20 : 5; and C22 : 6 main components. The anti-inflammatory and cytotoxic effects of crab lipids and phospholipids were investigated for the first time. …”
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