Promising LOX proteins for cartilage-targeting osteoarthritis therapy by Luca Morici, Eric Allémann, Olivier Jordan, Ines Nikolić

“…This review clarifies the main roles of different LOX proteins involved in the progression of OA. …”
Get full text

The Airflow Reversal Law in Ventilation System after Coal and Gas Outburst in Tunneling Roadway by Junhong Si, Yiqiao Wang, Genyin Cheng, Lin Li, Yitian Shao, Tan Li, Wei Hu

“…Considering the coal and gas outburst phenomenon in the mining space, this paper analyzes the main characteristics of coal and gas outburst accidents, defines the outburst airflow reversal degree, and constructs a simplified topology graph of tunneling ventilation system, while the air door is not destroyed. …”
Get full text

Unmasking health determinants and health outcomes for urban First Nations using respondent-driven sampling by J Smylie, M Firestone, S Maracle, M Spiller, P O'Campo

“…Objective Population-based health information on urban Aboriginal populations in Canada is limited due to challenges with the identification of Aboriginal persons in existing health data sets. The main objective of the Our Health Counts (OHC) project was to work in partnership with Aboriginal stakeholders to generate a culturally relevant, representative baseline health data set for three urban Aboriginal communities in Ontario, Canada.Design Respondent-driven sampling (RDS).Setting Hamilton, Ontario, Canada.Participants The OHC study, in partnership with the De dwa da dehs ney >s Aboriginal Health Access Centre (DAHC), recruited 554 First Nations adults living in Hamilton using RDS.Results Among First Nations adults living in Hamilton, 78% earned less than $20 000 per year and 70% lived in the lowest income quartile neighbourhoods. …”
Get full text

Ultraviolet-B Radiation and Nitrogen Affect Nutrient Concentrations and the Amount of Nutrients Acquired by Above-Ground Organs of Maize by Carlos M. Correia, João F. Coutinho, Eunice A. Bacelar, Berta M. Gonçalves, Lars Olof Björn, José Moutinho Pereira

“…Nutrient uptake decreased under high UV-B and increased with increasing N application, mainly at maturity harvest. Significant interactions UV-B x N were observed for NUE and for concentration and mass of some elements. …”
Get full text

Human Milk Archaea Associated with Neonatal Gut Colonization and Its Co-Occurrence with Bacteria by Maricarmen Salas-López, Juan Manuel Vélez-Ixta, Diana Laura Rojas-Guerrero, Alberto Piña-Escobedo, José Manuel Hernández-Hernández, Martín Noé Rangel-Calvillo, Claudia Pérez-Cruz, Karina Corona-Cervantes, Carmen Josefina Juárez-Castelán, Jaime García-Mena

“…Human colostrum and neonatal stools presented similar core microbiota, mainly composed of the methanogens <i>Methanoculleus</i> and <i>Methanosarcina</i>. …”
Get full text

Research progress of GLP-1RAs in the treatment of type 2 diabetes mellitus by Xu He, Xu He, Xu He, Wei Zhao, Wei Zhao, PeiHang Li, PeiHang Li, YinJiang Zhang, YinJiang Zhang, GuoHua Li, HongYu Su, BiNan Lu, BiNan Lu, ZongRan Pang, ZongRan Pang

“…Glucagon-like peptide-1 (GLP-1) is a 30-amino acid intestinal insulin-stimulating factor, which is mainly secreted by L cells in the distal ileum and colon. …”
Get full text

M. Fouladivanda, M. A. Heidary. A study into the impact of chloride ions on the make-up hydrogen compressors / trans. from Engl. M. A. Fedorova by M. A. Fedorova

“…XRD analysis has reported that the Iron Chloride Hydrate is the main part of the fouling sample. In this paper, the impact of the aforementioned chemicals on the compressor components are investigated, and some approaches are proposed to absorb or inhibit these chemicals.…”
Get full text

Recyclable Multifunctional PSOGs for Rapid Removal of Wastewater Pollutants (Oily and Dye) by Wannian Zhang, Yingquan Du, Zhigang Gao, Fang Yu, Yu‐Peng He

“…Partial 1H VT NMR, FTIR, and XRD experiments have shown that the main driving force for TBTC gelation and host–guest recognition originates from interaction hydrogen bonding, are TBTC specifically recognizes dye molecules through weak hydrogen bonding interactions and rapidly aggregates to form precipitates. …”
Get full text

Potential threats of glacial lake changes to the Sichuan-Tibet Railway by Menger Peng, Guoqing Zhang, Jinyuan Yu, Weicai Wang, Fenglin Xu, Sonam Rinzin

“…Of these lakes, this study identified 38 very high and 85 high GLOF-susceptibility lakes; mainly distributed along the Bomi-Nyingchi railway section in the Parlung Zangbo River basin. …”
Get full text

Follicular fluid lipidomics analysis reveals altered lipid signatures in patients with polycystic ovary syndrome by Qing He, Xiaoli Guo, Wenqiang Lv, Junchao Cui, Jing Meng, Xiao Gao, Jiachen Ma, Nan Zhou, Yijuan Cao

“…Phosphatidylcholine (PC), the main differentially expressed lipid, was significantly increased in the FF of the POCS group and was closely related to other lipids.Conclusions Using ultra-high-performance liquid chromatography–tandem mass spectrometry, we investigated lipid biomarkers based on FF lipidomics to provide useful information for the discovery of diagnostic markers for PCOS. …”
Get full text

Electrochemical Study and Determination of Homovanillic Acid, the Final Metabolite of Dopamine, Using an Unmodified Disposable Electrode by Mihaela Buleandră, Lavinia Georgiana Voica, Dana Elena Popa, Irinel Adriana Badea, Emilia Elena Iorgulescu, Mihaela Carmen Cheregi

“…This paper summarizes the main findings of a study which aimed to examine the electrochemical oxidation of homovanillic acid (HVA), the final metabolite of dopamine. …”
Get full text

Effect of Cyclic Expansion-Extrusion Process on Microstructure, Deformation and Dynamic Recrystallization Mechanisms, and Texture Evolution of AZ80 Magnesium Alloy by Yong Xue, Shuaishuai Chen, Haijun Liu, Zhimin Zhang, Luying Ren, Bing Bai

“…With the increase of CEE pass, the deformation mechanism changes from twinning to slipping and the DRX mechanism changes mainly from twinning-induced dynamic recrystallization (TDRX) to rotation dynamic recrystallization (RDRX) and then to continuous dynamic recrystallization (CDRX). …”
Get full text

Comprehensive analysis of advanced glycation end-products in commonly consumed foods: presenting a database for dietary AGEs and associated exposure assessment by Qiaozhi Zhang, Huatao Li, Ruixing Zheng, Lili Cao, Shufen Zhang, Shuifeng Zhang, Huadong Sheng, Yuhao Jiang, Yanbo Wang, Linglin Fu

“…The contents of these AGEs were detected in 334 foods covering all main groups consumed in Western and Chinese populations. …”
Get full text

Protein-ligand binding affinity prediction using multi-instance learning with docking structures by Hyojin Kim, Heesung Shim, Aditya Ranganath, Stewart He, Garrett Stevenson, Jonathan E. Allen

“…Our proposed method employs multi-instance learning with an attention network to predict binding affinity from a collection of docking poses.ResultsWe validate our method using multiple datasets, including PDBbind and compounds targeting the main protease of SARS-CoV-2. The results demonstrate that our method leveraging docking poses is competitive with other state-of-the-art inference models that depend on co-crystal structures.DiscussionThis method offers binding affinity prediction without requiring co-crystal structures, thereby increasing its applicability to protein targets lacking such data.…”
Get full text

Taxonomic and functional diversity of protists in saline and hypersaline lakes in southern Western Siberia, a region strongly affected by climate change by Elena A. Gerasimova, Alexander S. Balkin, Vladimir Y. Kataev, Ekaterina S. Filonchikova, Yulia V. Mindolina, Denis V. Tikhonenkov

“…The parasite amplicon sequence variants (ASVs) were affiliated mainly with mixohaline and beta-hypersaline lakes.…”
Get full text

Proposes Geometric Accuracy and Surface Roughness Estimation of Anatomical Models of the Pelvic Area Manufactured Using a Material Extrusion Additive Technique by Paweł Turek, Sławomir Snela, Grzegorz Budzik, Anna Bazan, Jarosław Jabłoński, Łukasz Przeszłowski, Robert Wojnarowski, Tomasz Dziubek, Jana Petru

“…One of the main benefits of using 3D printing in orthopedics is the ability to create custom solutions tailored to a patient’s specific anatomical and functional needs. …”
Get full text

Theoretical assessment of the effectiveness of application single-stage long-stroke piston compressors in refrigeration and hydrocarbon gas liquefaction systems by V. L. Yusha

“…The analysis of the main modern technologies for obtaining low temperatures and liquefying hydrocarbons using compressor equipment is presented and the most significant results of research in the field of low-flow compressors based on low-speed, long-stroke piston stages are presented. …”
Get full text

Ligature technique as a treatment for mucocele in an infant - Case report by Beatriz Cruz Lopes, Lucas Fernando Oliveira Tomáz Ferraresso, Mariella Padovese, Mariana Emi Nagata, Farli Aparecida Carrilho Boer, Cássia Cilene Dezan

“…It is commonly found in children due to oral habits, such as biting and sucking on lips and cheeks. The main treatment consists of complete surgical excision of the lesion and associated gland, which can be traumatic and invasive for children. …”
Get full text

Interfacial microstructure evolution behavior during plastic deformation bonding of GH4065A superalloy by SU Lidong, MENG Qingqi, NING Yongquan, HUANG Shuo, ZHANG Wenyun, ZHANG Beijiang

“…Moreover， the dynamic recrystallization（DRX）nuclei will grow toward the interface with ongoing deformation， contributing to the healing of the original interface.The metallurgical bonding caused by plastic deformation bonding mainly experiences three stages： initial contact， nucleation and grain growth， and joint formation.…”
Get full text

Numerical Investigations and Analysis of Cu2ZnSnS4 Based Solar Cells by SCAPS-1D by M. Djinkwi Wanda, S. Ouédraogo, F. Tchoffo, F. Zougmoré, J. M. B. Ndjaka

“…We found that the electrical parameters are seriously affected, when the absorber thickness is lower than 600 nm, mainly due to recombination at CZTS/Molybdenum interface that causes the short-circuit current density loss of 3.6 mA/cm2. …”
Get full text