Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway by Xiaoyu Zhang, Ping Zhu, Xiuying Zhang, Yina Ma, Wenguang Li, Ji-Mei Chen, Hui-Ming Guo, Richard Bucala, Jian Zhuang, Ji Li

“…Isoliquiritigenin (ISL), a simple chalcone-type flavonoid, is derived from licorice compounds and is mainly present in foods, beverages, and tobacco. Reactive oxygen species (ROS) is a critical factor involved in modulating cardiac stress response signaling during ischemia and reperfusion. …”
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Construction and high-throughput screening of gradient nanowire coatings on titanium surface towards ameliorated osseointegration by Ruiyue Hang, Yuyu Zhao, Huanming Chen, Xiaomei Li, Runhua Yao, Yonghua Sun, Xiaohong Yao, Long Bai, Huaiyu Wang, Yong Han, Ruiqiang Hang

“…The results showed that macrophages (MФs) that mainly governed the initial inflammatory reaction exhibited a polarization tendency towards pro-healing M2 phenotype with decreased nanowire dimension due to nanomorphology-mediated focal adhesion formation and activation of its downstream signaling pathways (typically PI3K-Akt). …”
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Ameliorative Effects of Raisin Polyphenol Extract on Oxidative Stress and Aging In Vitro and In Vivo via Regulation of Sirt1–Nrf2 Signaling Pathway by Wenjing Gao, Caiyun Zhao, Xin Shang, Bin Li, Jintian Guo, Jingteng Wang, Bin Wu, Yinghua Fu

“…In this work, 628 polyphenols in raisin extracts were characterized using UPLC-MS/MS, mainly including tricetin 3′-glucuronide, diisobutyl phthalate, butyl isobutyl phthalate, isoquercitrin and 6-hydroxykaempferol-7-O-glucoside. …”
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The Penha Garcia Ichnological Park at Naturtejo UNESCO Global Geopark (Portugal): a Geotourism Destination in the Footprint of the Great Ordovician Biodiversification Event by Carlos Neto de Carvalho, Andrea Baucon, Aram Bayet-Goll, João Belo

“…The in situ conservation of fossils in this ‘outside museum’ is a challenging subject, which is being monitored using 3D high-resolution modeling of the whole gorge and the main fossil sites there to an mm-scale precision.…”
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Assess the level of farmers' awareness regarding climate changes and its impacts on agriculture in Sétif province (north-east Algeria) by Nasri Samir, Belabbas Messaoud, Bouzid Hamza

“…Based on, some challenges have been revealed mainly: highlighting the need for effective dissemination of agricultural recommendations to improve farmers' knowledge that can support adaptation and mitigation toward climate change effects. …”
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Corrosion behavior of double-glow plasma copperizing coating on Q235 steel by Yang Z.-G., Liang W.-P., Jia Y.-L., Miao Q., Ding Z., Qi Y.

“…The corrosion products of Q235 steel were mainly β-FeOOH, γ-FeOOH, and α-FeOOH in the early stage of corrosion process. …”
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Bioinformatics approach reveals the critical role of inflammation-related genes in age-related hearing loss by Xi Gu, Chenyu Chen, Yuqing Chen, Chaojun Zeng, Yanchun Lin, Ruosi Guo, Shujin Xu, Chang Lin

“…Initially, a total of 105 Inflammatory related differentially expressed genes (IRDEGs) were obtained by overlapping the differentially expressed genes from the GSE49522 and GSE49543 datasets with Inflammatory related genes. The IRDEGs were mainly enriched in MAPK, PI3K-Akt, Hippo and JAK-STAT pathways by analysis of Gene Ontology and Kyoto Encyclopedia of Genes and Genomes. …”
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Investigation of the Suitability of the DTV Method for the Online SoH Estimation of NMC Lithium-Ion Cells in Battery Management Systems by Jan Neunzling, Philipp Hainke, Hanno Winter, David Henriques, Matthias Fleckenstein, Torsten Markus

“…Investigating the temperature behavior of lithium-ion battery cells has become an important part of today’s research and development. The main reason for this is that the temperature profile of a battery cell changes during aging. …”
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Altered Functional Connectivity in Children with ADHD Revealed by Scalp EEG: An ERP Study by Chunli Chen, Huan Yang, Yasong Du, Guangzhi Zhai, Hesheng Xiong, Dezhong Yao, Peng Xu, Jianhua Gong, Gang Yin, Fali Li

“…On the one hand, when investigating the cortical activity, HCs recruited much stronger brain activity mainly in the temporal and frontal regions, compared to ADHD children; on the other hand, the brain network showed atypical enhanced long-range connectivity between the frontal and occipital lobes but attenuated connectivity among frontal, parietal, and temporal lobes in ADHD children. …”
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Exploring the application of dietary antioxidant index for disease risk assessment: a comprehensive review by Hossein Pourmontaseri, Sina Bazmi, Matin Sepehrinia, Matin Sepehrinia, Ayda Mostafavi, Reza Arefnezhad, Reza Arefnezhad, Reza Homayounfar, Farhad Vahid

“…Dietary antioxidants can be obtained from various sources, mainly through a plant-based diet, including fruits and vegetables. …”
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TAD: A Large-Scale Benchmark for Traffic Accidents Detection From Video Surveillance by Yajun Xu, Huan Hu, Chuwen Huang, Yibing Nan, Yuyao Liu, Kai Wang, Zhaoxiang Liu, Shiguo Lian

“…The dataset is publicly available at <uri>https://github.com/UnicomAI/UnicomBenchmark/tree/main/TADBench</uri>.…”
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Expanding the Scope of Microvascular Inflammation: Unveiling Its Presence Beyond Antibody-Mediated Rejection Into T-Cell Mediated Contexts by Hilal Varol, Hilal Varol, Anne Wagenmakers, Konrad Hoeft, Konrad Hoeft, Jasper Callemeyn, Jasper Callemeyn, Roos Bodewes, Wichor Bramer, Andrew Stubbs, Andrew Stubbs, Rafael Kramann, Rafael Kramann, Maarten Naesens, Maarten Naesens, Marian C. Clahsen-Van Groningen, Marian C. Clahsen-Van Groningen, Marian C. Clahsen-Van Groningen

“…Microvascular inflammation (MVI) in kidney transplant biopsies is mainly associated with antibody-mediated rejection (AMR), sparking debate within the Banff Classification of Renal Allograft Pathology regarding its exclusivity. …”
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Algorithm of Strawberry Disease Recognition Based on Deep Convolutional Neural Network by Li Ma, Xueliang Guo, Shuke Zhao, Doudou Yin, Yiyi Fu, Peiqi Duan, Bingbing Wang, Li Zhang

“…In today's era of increasing demand for strawberry yield and quality, it is obvious that the traditional strawberry disease identification methods mainly rely on personal experience and naked eye observation and cannot meet the needs of people for strawberry disease identification and control. …”
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Research on wireless monitoring system for internal temperature field of coal gangue mountain by Xiaofei Liu, Chunhao Liang, Jifa Qian, Xiaolin Li, Xuemei Li, Baoli Li, Guang Xu, Bin Zhou

“…In addition, the system test indicates that the maximum effective transmission distance for penetration between the main control station and the node is 8 m, while the distance between the nodes is 7.14 m. …”
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International initiatives for the study of the human brain: EBRAINS and its Spanish node by Teris Duran, David Ezpeleta, Gemma Aragonès, Javier Mínguez, Emma Muñoz-Moreno, Maria V. Sanchez-Vives, Guillermo Velasco

“…The present article provides an overview of the main global initiatives that have emerged around the human brain in the last century, the achievements made, the most relevant technological capabilities, in what aspects they differ from other projects and the strategic vision of Europe in this neurotechnological era. …”
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Effects of different microplastics on the physicochemical properties and microbial diversity of rice rhizosphere soil by Sheng Lai, Sheng Lai, Sheng Lai, Cunzhong Fan, Ping Yang, Ping Yang, Yuanyuan Fang, Yuanyuan Fang, Lanting Zhang, Lanting Zhang, Minfei Jian, Guofei Dai, Guofei Dai, Jutao Liu, Jutao Liu, Huilin Yang, Liqin Shen, Liqin Shen

“…Furthermore, microplastics reduced the soil bacterial diversity index and altered the community structure of dominant bacterial species, with DOC content and FDA hydrolase being the main factors influencing the soil bacterial community. …”
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Construction of the ecological security pattern of Mu Us sandy land on the basis of the “Source − Resistance − Corridor” theory by Jiamin Li, Li’e Liang, Yan Chao, Xiaohan Wang, Mingming Qiu, Pingping Luo, Yonghua Zhu

“…A total of 29 ecological source areas were identified across the eight periods, with uneven spatial distributions, and they were mainly concentrated in the southern grassland area and the northern marginal area, with an average proportion of 26.32%. …”
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Anatomical and Functional Results Following 23-Gauge Primary Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment: Superior versus Inferior Breaks by Panagiotis Stavrakas, Paris Tranos, Angeliki Androu, Paraskevi Xanthopoulou, Dimitrios Tsoukanas, Polixeni Stamatiou, Panagiotis Theodossiadis

“…Methods. 160 eyes were enrolled in this study, divided into two groups based on break location: the superior break group (115 eyes) and the inferior break group (45 eyes). The main endpoint of our study was the anatomical success at 3 months following surgery. …”
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Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion and exploration by Xing Xiao, Gagik Yeghiazaryan, Fynn Eggersmann, Anna Lena Cremer, Heiko Backes, Peter Kloppenburg, Anne Christine Hausen

“…We show that dopaminergic neurons in these areas mainly express orexin receptor subtype 1 (Ox1R). In contrast, only a minor population in the medial ventral tegmental area express orexin receptor subtype 2 (Ox2R). …”
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Overcoming beta-lactam resistance in Pseudomonas aeruginosa by targeting metallo-beta-lactamase VIM-1: a one-microsecond molecular dynamics simulation study by Mohammed Salleh M. Ardawi, Samar A. Badreddine, Muhammad Yasir, Muhammad Yasir, Aiah M. Khateb, Aiah M. Khateb, Safaa A. Turkistani, Ahmed Afandi, Samah O. Noor, Adhari Alselmi, Adhari Alselmi, Vivek Dhar Dwivedi, Vivek Dhar Dwivedi, Esam I. Azhar, Esam I. Azhar

“…Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen with a high resistance to beta-lactam antibiotics, mainly due to the production of metallo-beta-lactamase VIM-1 (MBL-VIM-1) enzyme. …”
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