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121
LASSO–MOGAT: a multi-omics graph attention framework for cancer classification
Published 2024-08-01“…This article introduces Least Absolute Shrinkage and Selection Operator–Multi-omics Gated Attention (LASSO–MOGAT), a novel graph-based deep learning framework that integrates messenger RNA, microRNA, and DNA methylation data to classify 31 cancer types. …”
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122
Gene expression of psychiatric disorder-related kinesin superfamily proteins (Kifs) is potentiated in alternatively activated primary cultured microglia
Published 2025-01-01“…This allowed us to investigate the expression levels of psychiatric disorder-related Kifs messenger RNA (mRNA) in each condition. Kifs encode molecular motor proteins that transport cargo along microtubules, which are thought to dynamically reorganize during a substate change. …”
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123
Hydrogen Peroxide Is Involved in Salicylic Acid-Elicited Rosmarinic Acid Production in Salvia miltiorrhiza Cell Cultures
Published 2014-01-01“…These results indicated that H2O2 is secondary messenger for signal transduction, which can be induced by SA, significantly and promotes RA accumulation.…”
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124
A Sociopsychological Analysis of the Profiles of the Earliest Muslims and the Nature of the Islamic Call
Published 2024-11-01“…By “the end,” we mean that the divine will, which seeks to eradicate falsehoods, selects a new messenger to warn people about the corruption of previous beliefs and calls them to embrace a new religious formation. …”
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125
The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy
Published 2021-06-01“…MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression post-transcriptionally through specific pairing with target messenger RNAs (mRNAs). Extracellular vesicles (EVs), a heterogeneous group of cell-derived vesicles, transport miRNAs, mRNAs and intracellular proteins, and have been shown to promote horizontal malignancy into adjacent tissue, as well as resistance to conventional therapies. …”
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126
The role of microRNAs in learning and long-term memory
Published 2020-12-01“…MicroRNAs are unique endogenous non-coding RNAs about 22 nucleotides in length; each can regulate translation of hundreds of messenger RNA targets, thereby controlling entire gene networks. …”
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127
Hyperinsulinemia Induced Altered Insulin Signaling Pathway in Muscle of High Fat- and Carbohydrate-Fed Rats: Effect of Exercise
Published 2021-01-01“…Also, the levels of second messengers like IP3 and cAMP were increased with exercise. …”
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128
Advances in therapies using mesenchymal stem cells and their exosomes for treatment of peripheral nerve injury: state of the art and future perspectives
Published 2025-11-01“…The latter are nano-sized extracellular vesicles containing bioactive molecules such as proteins, microRNA, and messenger RNA derived from parent mesenchymal stem cells. …”
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129
Challenges and Choices Amidst Military Conflict: The Present and Future of Medical Education and Healthcare in Sudan
Published 2025-01-01“…We distributed the questionnaire electronically through an Online Google Form via social media platforms, such as WhatsApp Messenger. Descriptive statistics were employed for the data analyses. …”
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130
Genetic Manipulation of Calcium Release-Activated Calcium Channel 1 Modulates the Multipotency of Human Cartilage-Derived Mesenchymal Stem Cells
Published 2019-01-01“…Calcium is a ubiquitous intracellular messenger that has a crucial role in determining the proliferation, differentiation, and functions of multipotent mesenchymal stem cells (MSCs). …”
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131
Construction of AMPK-related circRNA network in mouse myocardial ischemia–reperfusion injury model
Published 2024-12-01“…A circRNA-miRNA-mRNA network consisting of 2 circRNA, 28 microRNA(miRNA) and 229 messengerRNA (mRNA) was constructed. Conclusions This study reveals the differential expression of several AMPK-related circRNAs in MIRI in mice, and the AMPK-related circRNA regulatory network is constructed, suggesting that AMPK-related circRNA may have potential clinical application prospects as a potential molecular marker and therapeutic target for MIRI.…”
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132
DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts
Published 2025-01-01“…Abstract Precursor messenger RNA (pre-mRNA) is processed into its functional form during RNA polymerase II (Pol II) transcription. …”
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133
Shenfu Injection Protects Brain Injury in Rats with Cardiac Arrest through Nogo/NgR Pathway
Published 2022-01-01“…The results of PCR and western blotting showed lower messenger ribonucleic acid and protein expression of NgR in Shenfu group than the model group and CWM group. …”
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134
Identification of the circRNA-miRNA-mRNA Regulatory Network in Bladder Cancer by Bioinformatics Analysis
Published 2021-01-01“…We obtained four datasets of circRNA, microRNA (miRNA), and messenger (mRNA) expression profiles from the Gene Expression Omnibus and The Cancer Genome Atlas microarray databases and identified 434, 367, and 4799/4841 differentially expressed circRNAs, miRNAs, and mRNAs, respectively. …”
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135
Effects of a multimedia campaign to increase human papillomavirus vaccine acceptance in Dhaka, Bangladesh
Published 2025-12-01“…Caregivers were recruited via Facebook and Instagram ads and interviewed through the Facebook Messenger App. About one-third of caregivers reported that their child had been vaccinated. …”
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136
The role of SAGA in the transcription and export of mRNA
Published 2019-03-01“…Sgf11 was found to be associated with the cap-binding complex (CBC) and recruited onto growing messenger ribonucleic acid (mRNA). Also, we have shown that Sgf11 interacted with the TREX-2/AMEX mRNA export complex and was essential for mRNA export from the nucleus. …”
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137
Deciphering the Impact of miR-92a-3p on Controlling BCL11A Gene Expression and Its Implication in Easing Thalassemia Symptoms
Published 2024-10-01“…The process involved the addition of the polyadenosine monophosphate enzyme Poly-A to facilitate the production of mature messenger RNA (mRNA) from DNA. Results: The study revealed significantly elevated miR-92a expression in blood cells. …”
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138
Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals
Published 2023-06-01“…The objective of this study was to evaluate the vaccinations adverse effects as well as determine the immunogenicity of the messenger ribonucleic acid (mRNA) BNT162b2 vaccines through the production of IgG and neutralizing antibodies against the protein s subunit. …”
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139
Assessment of the Preservation and Conservation of Teachers’ Records at Rubanda District Local Government
Published 2023“…Descriptive research design was used and a sample size of 17 respondents was used and these included 4 records staff (one records manager, two records assistants and one office messenger) and 10 teachers and 3 administrators. Data collection methods used included questionnaire method and interviewing method. …”
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140
Stem Cell-Derived Nanovesicles: A Novel Cell-Free Therapy for Wound Healing
Published 2021-01-01“…CDNs can shuttle various proteins, messenger RNAs, and microRNAs to regulate the activity of receptor cells, and they play important roles in skin wound healing. …”
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