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Computational analysis of SARS-CoV-2, SARS-CoV, and MERS-CoV genome using MEGA
Published 2020-09-01“…Overall the genomic data analysis of SARS-CoV-2, SARS-CoV, and MERS-CoV highlights the close genetic relationship.…”
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Low-Level Zoonotic Transmission of Clade C MERS-CoV in Africa: Insights from Scoping Review and Cohort Studies in Hospital and Community Settings
Published 2025-01-01Subjects: “…MERS-CoV…”
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Middle East respiratory syndrome coronavirus (MERS-CoV) internalization does not rely on DPP4 cytoplasmic tail signaling
Published 2024-12-01“…Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) infects respiratory epithelial cells in humans and camels by binding to dipeptidyl peptidase 4 (DPP4) as its entry receptor. …”
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Lessons from SARS-CoV, MERS-CoV, and SARS-CoV-2 Infections: What We Know So Far
Published 2022-01-01“…Since November 2002, three highly pathogenic and major deadly human coronaviruses of the βετα-genera (β-hCoVs), namely, severe acute respiratory distress syndrome-coronavirus (SARS-CoV), middle east respiratory syndrome-coronavirus (MERS-CoV), and SARS-CoV-2, have been globally emerged and culminated in the occurrence of SARS epidemic, MERS outbreak, and coronavirus disease 19 (COVID-19) pandemic, respectively. …”
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MERS-CoV spike vaccine-induced N-terminal domain-specific antibodies are more protective than receptor binding domain-specific antibodies
Published 2025-02-01“…To study which epitopes and subdomains contribute to in vivo protection, we utilized the prefusion-stabilized spike protein of MERS-CoV, MERS S-2P, as a vaccine immunogen. Vaccination with MERS S-2P elicited both receptor-binding domain (RBD)- and non-RBD-specific antibodies, including N-terminal domain (NTD)-specific G2-and CDC2-A2-like antibodies. …”
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Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis
Published 2020-12-01Subjects: “…SARS-CoV2, SARS-CoV, MERS-CoV, COVID-19 and 2019-nCoV…”
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Design, synthesis and molecular docking of novel triazole derivatives as potential CoV helicase inhibitors
Published 2020-06-01“…Middle East respiratory syndrome coronavirus (MERS-CoV) had emerged and spread because of the worldwide travel and inefficient healthcare provided for the infected patients in several countries. …”
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Betacoronaviruses Differentially Activate the Integrated Stress Response to Optimize Viral Replication in Lung-Derived Cell Lines
Published 2025-01-01“…Using a small molecule inhibitor of eIF2α dephosphorylation, we provide evidence that MERS-CoV and HCoV-OC43 maximize viral replication through p-eIF2α dephosphorylation. …”
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Neurological Complications of Middle East Respiratory Syndrome Coronavirus: A Report of Two Cases and Review of the Literature
Published 2016-01-01“…Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was first discovered in September 2012 in Saudi Arabia. …”
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Replication-transcription complex of coronaviruses: functions of individual viral non-structural subunits, properties and architecture of their complexes
Published 2022-04-01“…Severe acute respiratory syndrome CoV (SARS-CoV), Middle East respiratory syndrome CoV (MERS-CoV), and the novel coronavirus (2019-nCoV, SARS-CoV-2) have been identif ied as causing global pandemics. …”
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Creation of transgenic mice susceptible to coronaviruses: a platform for studying viral pathogenesis and testing vaccines
Published 2022-07-01“…Over the past 20 years, coronaviruses have caused three epidemics: SARS-CoV, MERS-CoV, and SARS-CoV2, with the first two having a very high lethality of about 10 and 26 %, respectively. …”
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Conserved role of spike S2 domain N-glycosylation across betacoronaviruses
Published 2025-01-01“…In addition to SARS-CoV-2, deleting stem N-glycans in SARS-CoV and MERS-CoV spike also prevented viral entry into target cells. …”
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COVID-19: Changing Trends and Its Impact on Future of Dentistry
Published 2020-01-01“…It is a novel virus which is distinct from SARS-CoV and MERS-CoV, with Chinese horseshoe bats being the most probable origin. …”
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The WHO Disease Outbreak News during the Covid-19 pandemic.
Published 2025-01-01“…We find that multinational epidemics of diseases like Ebola virus and MERS-CoV continue to dominate the DON. However, recent years have also seen more reports of climate-sensitive infectious diseases, as well as a state shift in influenza outbreak reporting in both China and the rest of the world. …”
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COVID-19: Gastrointestinal Manifestations and Complications
Published 2021-11-01“…This genus also includes the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV). The common symptoms of COVID-19 infection are fever and respiratory symptoms, but it can also involve the gastrointestinal tract (GIT), resulting in manifestations such as diarrhea, nausea and/or vomiting and abdominal pain. …”
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Stability, Bifurcation, and a Pair of Conserved Quantities in a Simple Epidemic System with Reinfection for the Spread of Diseases Caused by Coronaviruses
Published 2021-01-01“…This model can be applied to study epidemics caused by SARS-CoV, MERS-CoV, and SARS-CoV-2 coronaviruses, since there is the possibility that, in diseases caused by these pathogens, individuals recovered from the infection have a decrease in their immunity and can be reinfected. …”
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Patterns of Isoform Variation for N Gene Subgenomic mRNAs in Betacoronavirus Transcriptomes
Published 2024-12-01“…Positions of junction breakpoints relative to stem loop 3 in the 5′-UTR suggest similar mechanisms in SARS-CoV, SARS-CoV-2, and OC43, but not in MERS-CoV. These observations may be pertinent for antisense-based antiviral strategies.…”
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SARS and MERS as learning tools for addressing the 2019-nCoV epidemic: A mini-review
Published 2020-07-01“…Issues such as sub-par personal hygiene, overcrowding, and mass panic exacerbated the spread of the Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and Middle East Respi- ratory Syndrome coronavirus (MERS-CoV ), serving as crucial lessons for understanding the 2019-nCoV. …”
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Network Analysis of MERS Coronavirus within Households, Communities, and Hospitals to Identify Most Centralized and Super-Spreading in the Arabian Peninsula, 2012 to 2016
Published 2018-01-01“…The transmission connectivity networks of people infected with highly contagious Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia were assessed to identify super-spreading events among the infected patients between 2012 and 2016. …”
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