Editorial: Current insights in Epigenetics and Epigenomics by Steven Henikoff, Steven Henikoff, Sharon Y. R. Dent, Sharon Y. R. Dent, Raul Mostoslavsky, Raul Mostoslavsky, Ting Wang, Luca Comai

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High Frequency Microsatellite Instability Has a Prognostic Value in Endometrial Endometrioid Adenocarcinoma, But Only in FIGO Stage 1 Cases by Anita Steinbakk, Anais Malpica, Aida Slewa, Einar Gudlaugsson, Emiel A. M. Janssen, Mark Arends, Arnold Jan Kruse, Yu Yinhua, Weiwei Feng, Jan P. Baak

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Current Challenges and Potential Solutions for Targeted Drug Delivery (TDD) in Cancer Pain Management by Chung M, Kalia H, Schatman ME, Robinson CL

“…Matthew Chung,1 Hemant Kalia,2 Michael E Schatman,3,4 Christopher L Robinson5 1Department of Pain Medicine, Division of Anesthesia, Critical Care and Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 2Center for Research and Innovation in Spine and Pain (C.R.I.S.P.), Rochester, NY, USA; 3Department of Anesthesiology, Perioperative Care, and Pain Medicine, NYU Grossman School of Medicine, New York, NY, USA; 4Department of Population Health-Division of Medical Ethics, NYU Grossman School of Medicine, New York, NY, USA; 5Department of Anesthesiology, Perioperative, and Pain Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USACorrespondence: Matthew Chung, The University of Texas MD Anderson Cancer Center, 1400 holcombe Boulevard, Unit 409, Houston, TX, 77030, USA, Email mchung1@mdanderson.org…”
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Venetoclax plus low-intensity chemotherapy for adults with acute lymphoblastic leukemia by Marlise R. Luskin, Shai Shimony, Julia Keating, Eric S. Winer, Jacqueline S. Garcia, Richard M. Stone, Elias Jabbour, Yael Flamand, Kristen Stevenson, Jeremy Ryan, Zhihong Zeng, Anthony Letai, Marina Konopleva, Nitin Jain, Daniel J. DeAngelo

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Survey and perspective on verification, validation, and uncertainty quantification of digital twins for precision medicine by Kaan Sel, Andrea Hawkins-Daarud, Anirban Chaudhuri, Deen Osman, Ahmad Bahai, David Paydarfar, Karen Willcox, Caroline Chung, Roozbeh Jafari

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Resveratrol Induces Differentiation of Human Umbilical Cord Mesenchymal Stem Cells into Neuron-Like Cells by Li Guo, Liang Wang, Li Wang, Shi Yun-peng, Jing-jing Zhou, Zongmao Zhao, De-Pei Li

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First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors by Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna

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GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth by Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Michael G Rosenblum, Brian Aguirre, Cheng-Hsiang Lu, Anubhav Chandla, Nidhi Kejriwal, Lucia Liu, Ann M Chan, SuYin Kok, Sergio Duarte, David Casero, Madhuri Wadehra

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A morphometric signature to identify ductal carcinoma in situ with a low risk of progression by Marcelo Sobral-Leite, Simon P. Castillo, Shiva Vonk, Hendrik A. Messal, Xenia Melillo, Noomie Lam, Brandi de Bruijn, Yeman B. Hagos, Myrna van den Bos, Joyce Sanders, Mathilde Almekinders, Lindy L. Visser, Emma J. Groen, Petra Kristel, Caner Ercan, Leyla Azarang, Jacco van Rheenen, E. Shelley Hwang, Yinyin Yuan, Grand Challenge PRECISION Consortium, Renee Menezes, Esther H. Lips, Jelle Wesseling

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Neural Mechanisms of Autonomic Dysfunction in Neurological Diseases by De-Pei Li, Yu-Long Li, Jianhua Li, Sheng Wang

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Gray matter volume and asymmetry in Broca's and Wernicke's area homologs in chimpanzees (Pan troglodytes) using a probabilistic region of interest approach by William D Hopkins, Muhammad A Spocter, Michele M Mulholland, Chet C Sherwood

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Adaptive and Sequential Methods for Clinical Trials by Yichuan Zhao, Zhengjia Chen, Xuelin Huang, Mourad Tighiouart

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A paper-based HPV E7 oncoprotein assay for cervical precancer detection at the point of care by Chelsey A. Smith, Sai Paul, Karen E. Haney, Sonia G. Parra, Meaghan Bond, Leticia López, Mauricio Maza, Juan Felix, Preetha Ramalingam, Pablo Escobar, Philip E. Castle, Kathleen M. Schmeler, Rebecca R. Richards-Kortum

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The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity by Mustafa Sibai, Sergi Cervilla, Daniela Grases, Eva Musulen, Rossana Lazcano, Chia-Kuei Mo, Veronica Davalos, Arola Fortian, Adrià Bernat, Margarita Romeo, Collin Tokheim, Jordi Barretina, Alexander J. Lazar, Li Ding, Enrique Grande, Francisco X. Real, Manel Esteller, Matthew H. Bailey, Eduard Porta-Pardo, Enrique Grande, Teresa Alonso-Gordoa, Mario Álvarez-Maestro, Elena Andrada, Ainara Azueta, Raquel Benítez Javier Burgos, Daniel Castellano, M. Angel Climent, Mario Domínguez, Ignacio Durán Albert Font, Isabel Galante, Patricia Galván, Juan F. García, Xavier García del Muro, Félix Guerrero-Ramos, Núria Malats, Miriam Marqués, Pablo Maroto, Jaime Martínez de Villarreal, Ane Moreno-Oya, Jesús M. Paramio, Alvaro Pinto, Aleix Prat, Javier Puente, Oscar Reig, Francisco X. Real

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Editorial: Exploring genomic instability of cancers: applications in diagnosis and treatment by Dong Zhang, Dong Zhang, Shiaw-Yih Lin, Marietta Lee

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Editorial: Deciphering the regulatory role of transcription factors in cancer immune infiltration by Qian Yang, Qian Yang, Jinfen Xiao, Yujia Lan

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Editorial: Pediatric CNS tumors in low- and middle-income countries: expanding our understanding by Diana S. Osorio, Ibrahim Qaddoumi, Ibrahim Qaddoumi, Daniel C. Moreira, Daniel C. Moreira

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Nursing knowledge in cardio-oncology: results of an international learning needs-assessment survey by Anecita Fadol, Geraldine Lee, Valerie Shelton, Kelly C. Schadler, Asma Mohammed Younus, Mary Stuart, Lisa Nodzon, Edith Pituskin

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Entamoeba gingivalis in Acute Osteomyelitis of the Mandible by Feriyl Bhaijee, Diana Bell

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Genomic Profiling of Liver Cancer by Ju-Seog Lee

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