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Doxycycline-integrated silk fibroin hydrogel: preparation, characterizations, and antimicrobial assessment for biomedical applications
Published 2025-02-01“…The zone of inhibition was smaller with SF-DH hydrogels compared with DH for both Staphylococcus aureus and Streptococcus mutans. Furthermore, MC3T3-E1 cells showed 90% viability with SF-DH hydrogel. …”
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The guanine nucleotide exchange factor DOCK5 negatively regulates osteoblast differentiation and BMP2-induced bone regeneration via the MKK3/6 and p38 signaling pathways
Published 2025-01-01“…C21 significantly enhanced osteoblast differentiation and mineral deposition in mouse MC3T3-E1 cells and in human and mouse BMSCs. Dock5 knockout (KO) mice exhibited increased bone mass and mineral apposition rate, with their BMSCs showing enhanced osteoblast differentiation. …”
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5544
Evaluation of Safety and Efficacy of a Single Lorecivivint Injection in Patients with Knee Osteoarthritis: A Multicenter, Observational Extension Trial
Published 2025-01-01“…A post hoc baseline-adjusted analysis of covariance (ANCOVA) compared changes from baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain and Function subscores and medial joint space width (JSW) between LOR 0.07 mg and PBO groups in a subpopulation of participants with unilateral knee pain and widespread pain low enough to allow participants to differentiate their target knee pain. …”
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5545
A high offset stem design does not increase stem migration under full weight bearing in cementless total hip arthroplasty: a model-based RSA study
Published 2025-02-01“…Clinical outcomes were assessed using the modified Harris Hip Score (HHS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). …”
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5546
Gender beliefs and norms underlying intimate partner violence stigma among women living in Botswana: Results of an exploratory factor analysis.
Published 2025-01-01“…For each EFA identified scale, we estimated reliability (McDonald's omega (ω)) and correlation with psychosocial outcomes related to IPV stigma. …”
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5547
Appendicular Skeletal Muscle Index Is Positively Related to Mediterranean Diet Adherence in University Students
Published 2024-12-01“…Anthropometry and bioimpedance analysis (TANITA-MC780) were performed. The aSMI was calculated as the sum of the upper and lower extremity muscle masses divided by height squared. …”
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5549
Polymeric Multivalent Fc Binding Peptides‐Fabricated Clinical Compounding Bispecific Antibody Potentiates Dual Immunotherapy Targeting PD1 and CTLA‐4
Published 2025-01-01“…PD1/CTLA‐4 BsAb significantly inhibits tumors in MC38 colon cancer‐bearing mice more effectively than the combination of aPD1 and aCTLA‐4, with tumor suppression rates of 96.8% and 77.3%, respectively. …”
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A randomized controlled study on the effectiveness of a diabetes self-management app in Bangladesh
Published 2024-12-01“…Knowledge and adherence were measured and compared in the different groups before and after the intervention using t-test, McNemar’s test, and logistic regression technique. …”
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5553
Biochar Derived from Domestic Sewage Sludge: Influence of Temperature Pyrolysis on Biochars’ Chemical Properties and Phytotoxicity
Published 2021-01-01“…The raw sewage sludge and the produced biochars have been analyzed to determine their volatile organic matter (VOM), mineral content (MC), nutrients’ level (total nitrogen TN, available phosphorus P, and potassium K), alkalinity (pH), and salinity (electrical conductivity EC and Na). …”
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5554
The mechanisms of melanogenesis inhibition by glabridin: molecular docking, PKA/MITF and MAPK/MITF pathways
Published 2023-01-01“…The treatment by glabridin significantly downregulated both transcriptional and/or protein expression of melanogenesis-related factors including melanocyte stimulating hormone receptor (MC1R), microphthalmia-associated transcription factor (MITF), tyrosinase (TYR), TYR-related protein-1 (TRP-1) and TRP-2 in B16 cells. …”
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5555
A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management
Published 2021-07-01Get full text
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5556
Nurturing care during COVID-19: a rapid review of early evidence
Published 2022-06-01Get full text
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5557
Tracing the Origin of Oxide Inclusions in Vacuum Arc Remelted Steel Ingots Using Trace Element Profiles and Strontium Isotope Ratios
Published 2025-01-01“…In this study, the potential of elemental and isotopic fingerprinting to trace the sources of macroscopic oxide NMIs found in VAR-treated steel ingots using SEM-EDX, inductively coupled plasma mass spectrometry (ICP-MS), laser ablation ICP-MS (LA-ICP-MS), and laser ablation multicollector ICP-MS (LA-MC-ICP-MS) were exploited. Following this approach, main and trace element content and <sup>87</sup>Sr/<sup>86</sup>Sr isotope ratios were determined in two specimens of macroscopic NMIs, as well as in samples of potential source materials. …”
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Nursing knowledge in cardio-oncology: results of an international learning needs-assessment survey
Published 2025-01-01Get full text
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