Physicians’ moral distinctions between medical assistance in dying (MAiD) and withdrawing life-sustaining treatment in Canada: a qualitative descriptive study by Midori Matthew, Kieran Bonner, Andrew Stumpf

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Genomic signatures of selection in Brangus cattle revealing the genetic foundations of adaptability and production traits using a breed of origin approach by Gabriel A. Zayas, Raluca G. Mateescu

“…Key genomic regions were identified on chromosomes 6, 8, 10, 12, 14, 17, 18, 19, 27, and 28, and were linked to traits such as fertility, growth, heat tolerance, carcass characteristics, and meat quality.DiscussionExpected genes showing signatures of selection included MC1R, responsible for black coat color, and PLAG1, integral to growth, fertility, and carcass traits, underscoring the effectiveness of this methodology. …”
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N6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell Fate by Pengfei Ji, Xia Wang, Nina Xie, Yujing Li

“…Among the base modification markers extensively studied, 5-methylcytosine (5-mC) and its oxidative derivatives (5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC), and 5-carboxylcytosine (5-caC)) dynamically occur in DNA and RNA and have been acknowledged as important epigenetic markers involved in regulation of cellular biological processes. …”
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Comparative evaluation of marginal fit accuracy of two different designs of endocrown manufactured through CAD-CAM system: An in vitro study by Khushbu Rakesh Gupta, Deepesh Kumar Gupta, Anumeha Jha, Shivam B. Shukla, Aayush Mukund Dubey

“…The STL file format is translated into millable data file format (CNC- Computer numerical control) in the inLAB MC X5 Milling machine. The marginal fit of endocrowns was then assessed in the stereomicroscope. …”
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The optic radiations and reading development: A longitudinal study of children born term and preterm by Lisa Bruckert, Garikoitz Lerma-Usabiaga, Lauren R. Borchers, Virginia A. Marchman, Katherine E. Travis, Heidi M. Feldman

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Neutrinoless double beta decay from scalar leptoquarks: interplay with neutrino mass and flavor physics by P. S. Bhupal Dev, Srubabati Goswami, Chayan Majumdar, Debashis Pachhar

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Design of a new class of broad-spectrum therapeutics targeted to drug-resistant bacteria by Amrutha Surendran, Agnes Turnbull, Allen Flockhart, Fern Findlay-Greene, Martyna Nowosielska, Donald Morrison, David J. Mincher, Samantha Donnellan

“…Herein we present the synthesis of two novel spacer-linked, anthraquinone-triphenylphosphonium (AQ-TPP) conjugates (4) and (5) as early lead compounds in a new class of agent designed to penetrate the lipophilic barriers of the membranes of a diverse family of species; and establish bacterial growth inhibitory properties against methicillin-resistant Staphylococcus aureus (NCTC 13616) and Mycobacterium smegmatis [mc2155] (as a surrogate for Mycobacterium tuberculosis). …”
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Effects of proton pump inhibitors and histamine-2 receptor antagonists on response to fidaxomicin or vancomycin in patients with Clostridium difficile-associated diarrhoea by Thomas Louie, Karl Weiss, Mark A Miller, Kathleen Mullane, Derrick W Crook, Sherwood L Gorbach

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Evidence-based Algorithms for Free Deep Inferior Epigastric Perforator Flap Salvage in Autologous Breast Reconstruction by Anna R. Todd, MD, PhD, FRCSC, Mawaddah Alrajraji, MD, Kathryn Sawa, MD, Joan E. Lipa, MD, MSc, Laura Snell, MD, MSc

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Allergen degradation of bee pollen by lactic acid bacteria fermentation and its alleviatory effects on allergic reactions in BALB/c mice by Shuting Yin, Qiangqiang Li, Yuxiao Tao, Enning Zhou, Kun Wang, Wanwen Chen, Xiangxin Li, Liming Wu

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Genetic Variation and Population Structure in Jamunapari Goats Using Microsatellites, Mitochondrial DNA, and Milk Protein Genes by P. K. Rout, K. Thangraj, A. Mandal, R. Roy

“…The observed mean M ratio in the population was above the critical significance value (Mc) and close to one indicating that it has maintained a slowly changing population size. …”
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Revisiting Weimar Film Reviewers’ Sentiments: Integrating Lexicon-Based Sentiment Analysis with Large Language Models by Isadora Campregher Paiva, Josephine Diecke

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Optimization Configuration Method of Energy Storage Considering Photovoltaic Power Consumption and Source-Load Uncertainty by Junjie Qiao, Xiaofang Meng, Weigang Zheng, Pengxue Huang, Tiefeng Xu, Yupeng Xu

“…Firstly, a PV and load uncertainty model is established based on Beta and Normal distributions, and the Monte Carlo Method (MC) is used to simulate the annual output. The representative scenarios are obtained after the combination is cut down by the K-means clustering algorithm. …”
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Refining the interpretation of variants of uncertain significance in hereditary cancer screening through integrated RNA sequencing by Youbao Sha, J. Bryce Ortiz, Sara L. Bristow, Kate Loranger, Linyan Meng, Xiaonan Zhao, Fan Xia, Sheetal Parmar, Adam C. ElNaggar, Wenbo Xu

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Helikopter Anababalık ve Özerklik Destekleyici Davranışlar Ölçeği’nin Türkçeye Uyarlanması: Geçerlik ve Güvenirlik Çalışması by Figen Çok, Cansu Hazal Güçlü, Semih Topuz, H. Kübra Özdoğan

“…Bu çalışmanın amacı Schiffrin, Liss, Miles-McLean, Geary, Erchull ve Tashner tarafından geliştirilen Helikopter Anababalık ve Özerklik Destekleyici Davranışlar Ölçeği’nin (HAÖDD) Türkçeye kazandırılması, geçerlik ve güvenirliğinin incelenmesidir. …”
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GDF-15 Is Associated with Poor Physical Function in Prefrail Older Adults with Diabetes by Reshma Aziz Merchant, Yiong Huak Chan, Gustavo Duque

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A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity by Da-yan Zhang, Zhi-hua Zhang, Wen-ting Liu, Wei-ming Zhou, Peng-fei Zhou, Juan-juan Wei, Xue-jing Dai, Xiao-li Zeng, Yu-qiong Zhou, Han-wang Li, Heng Zhang, Ao-lin Shen, Lian-sheng Cheng, Guo-dong Shen, Yi-fu He

“…In vivo antitumour activity was assessed by establishing humanized mice bearing human MSLN-expressing MC38 (MC38/hMSLN) or CT26 (CT26/hMSLN) cells, and safety was further evaluated in cynomolgus monkeys. …”
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Effectiveness of a universal film intervention in reducing violence against children and increasing positive parenting among migrant and displaced caregivers from Myanmar: a commun... by Amanda Sim, Khaing Zar Lwin, Stephanie Eagling-Peche, G.J. Melendez-Torres, Seema Vyas, Francisco Calderon, Tawanchai Jirapramukpitak, Jamie Lachman, Sureeporn Punpuing, Andrea Gonzalez, Mary Soan, Nway Nway Oo, Ivet Castello Mitjans, Greg Tyrosvoutis, Eve Puffer

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Editorial by Jörg Tremmel, Maria Lenk, Antony Mason, Markus Rutsche

“…Unlike other index-builders, McQuilkin takes great pains to lay out all the premises, definitions and data sources of his account in as clear a manner as possible, which makes his article an accessible and instructive read. …”
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Robotic Versus Laparoscopic Liver Resection: A Nationwide Propensity Score Matched Analysis by Gabriela Pilz da Cunha, MD, Jasper P. Sijberden, MD, PhD, Susan van Dieren, PhD, Paul Gobardhan, MD, PhD, Daan J. Lips, MD, PhD, Türkan Terkivatan, MD, PhD, Hendrik A. Marsman, MD, PhD, Gijs A. Patijn, MD, PhD, Wouter K. G. Leclercq, MD, PhD, Koop Bosscha, MD, PhD, J. Sven D. Mieog, MD, PhD, Peter B. van den Boezem, MD, PhD, Maarten Vermaas, MD, PhD, Niels F. M. Kok, MD, PhD, Eric J. T. Belt, MD, PhD, Marieke T. de Boer, MD, PhD, Wouter J. M. Derksen, MD, PhD, Hans Torrenga, MD, PhD, Paul M. Verheijen, MD, PhD, Steven J. Oosterling, MD, PhD, Arjen M. Rijken, MD, PhD, Marielle M. E. Coolsen, MD, PhD, Mike S. L. Liem, MD, PhD, T.C. Khé Tran, MD, PhD, Michael F. Gerhards, MD, PhD, Vincent Nieuwenhuijs, MD, PhD, Mohammad Abu Hilal, MD, PhD, Marc G. Besselink, MD, PhD, Ronald M. van Dam, MD, PhD, Jeroen Hagendoorn, MD, PhD, Rutger-Jan Swijnenburg, MD, PhD, for the Dutch Hepatobiliary Audit Group

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