Costimulation of Murine Osteoblasts with Interferon-γ and Tumor Necrosis Factor-α Induces Apoptosis through Downregulation of Bcl-2 and Release of Cytochrome c from Mitochondria by Mayumi Iguchi, Miki Hiroi, Haruhide Kanegae, Yoshihiro Ohmori

“…To elucidate the underlying molecular mechanisms, we investigated the effect of IFNγ and TNFα on the proliferation and survival of clonal MC3T3-E1 mouse osteoblasts. We found that although IFNγ or TNFα alone affected cell growth and survival only marginally, costimulation with both synergistically inhibited cell growth and reduced cell viability. …”
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Energy-related contaminants in subterranean waterbodies: The role of geocolloids on facilitated and hindered transport by Mustafa E.S. Akbulut, Younjin Min

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Effect of Task Specific Exercises, Gait Training, and Visual Biofeedback on Equinovarus Gait among Individuals with Stroke: Randomized Controlled Study by Mohamed Elsayed Khallaf, Ahmed Maher Gabr, Eman Elsayed Fayed

“…All the patients were at stage 4 of motor recovery of foot according to Chedoke-McMaster Stroke Assessment without any cognitive dysfunction. …”
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In Vitro Osteogenic Properties of Two Dental Implant Surfaces by Marta Monjo, Christiane Petzold, Joana Maria Ramis, Staale Petter Lyngstadaas, Jan Eirik Ellingsen

“…The aim of the study was to perform a full characterization of the effect of two commercial titanium (Ti) surfaces, OsseoSpeed and TiOblast, on the behaviour of mouse preosteoblast MC3T3-E1 cells. The effect of these Ti surfaces was compared with tissue culture plastic (TCP). …”
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Neural markers of error processing relate to task performance, but not to substance-related risks and problems and externalizing problems in adolescence and emerging adulthood by Olga D. Boer, Thea Wiker, Shervin H. Bukhari, Rikka Kjelkenes, Clara M.F. Timpe, Irene Voldsbekk, Knut Skaug, Rune Boen, Valerie Karl, Torgeir Moberget, Lars T. Westlye, Ingmar H.A. Franken, Hanan El Marroun, Rene J. Huster, Christian K. Tamnes

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Information System Success Model untuk Evaluasi Sistem Informasi Penataan Ruang Kota berbasis Geographic Information System (GIS) by Heni Vidia Sari, Ismiarta Aknuranda, Fatwa Ramdani

“…Untuk melakukan evaluasi kesuksesan SI terdapat model kesuksesan yang dapat digunakan salah satunya adalah model kesuksesan DeLone & McLean (D&M). Namun, menarik untuk diketahui apakah model D&M sudah cukup komprehensif untuk mengevaluasi GIS pada sektor publik seperti Sipetarung. …”
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A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment by Sandra Viz-Lasheras, Alberto Gómez-Carballa, Xabier Bello, Irene Rivero-Calle, Ana Isabel Dacosta, Myrsini Kaforou, Dominic Habgood-Coote, Aubrey J. Cunnington, Marieke Emonts, Jethro A. Herberg, Victoria J. Wright, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Daniela S. Kohlfürst, Nina Schweintzger, Michiel Van der Flier, Ronald de Groot, Luregn J. Schlapbach, Philipp Agyeman, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Ulrich Von Both, Marko Pokorn, Dace Zavadska, María Tsolia, Henriëtte A. Moll, Clementien Vermont, Michael Levin, Federico Martinón-Torres, Antonio Salas, On behalf of EUCLIDS, PERFORM, and DIAMONDS consortia

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Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy by James Dooley, Bart Neyns, Elizabeth Allen, Frank Tacke, Louis Boon, Damya Laoui, Julia Katharina Schwarze, Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, Kiavash Movahedi, Niels Vandamme, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Jo Agnes Van Ginderachter

“…These findings were validated by flow cytometric analysis of both mouse (LLC-OVA, MC38 and B16-OVA) and human (NSCLC and melanoma) tumor samples. …”
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Ebola Virus and SARS-CoV-2: Similarities and Differences by Robert C. SIZEMORE, Md S. ZAMAN

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Integrative genetics and multiomics analysis reveal mechanisms and therapeutic targets in vitiligo highlighting JAK STAT pathway regulation of CTSS by Zi-yue Dong, Ming-jie He, Yong-kai Yu, Fang Wang, Peng-yuan Zhao, De-long Ran, De-shuang Fu, Qing He, Run-ping Yang, Jiang-an Zhang

“…Our GWAS-meta analysis pinpointed five druggable genes: ERBB3, RHOH, CDK10, MC1R, and NDUFAF3, and underwent drug target exploration and molecular docking. …”
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Risky Behaviors among HIV-Positive Female Sex Workers in Northern Karnataka, India by Apoorva Jadhav, Parinita Bhattacharjee, T. Raghavendra, James Blanchard, Stephen Moses, Shajy Isac, Shiva S. Halli

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Phenolic compounds of Iris adriatica and their antimycobacterial effects by Ochensberger Sandra, Alperth Fabian, Mitić Božena, Kunert Olaf, Mayer Stefanie, Mourão Maria Ferreira, Turek Ivana, Luca Simon Vlad, Skalicka-Woźniak Krystyna, Maleš Željan, Hruševar Dario, Duka Ivan, Bucar Franz

“…We therefore performed a bioassay-guided fractionation including high-performance counter current chromatography (HPCCC) and antibacterial tests using Mycobacterium smegmatis mc2 155. One obtained fraction was found to be antimycobacterially active with a MIC of 64 mg L−1. …”
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Association of Alzheimer’s and Lewy body disease pathology with basal forebrain volume and cognitive impairment by Julia Schumacher, Stefan Teipel, Alexander Storch

“…Associations of regional volumes with pathological markers (Braak stage, CERAD score, and McKeith criteria for LB pathology) and cognitive performance were assessed using Bayesian statistical methods. …”
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Quantitative 3-D investigation of faulting in deep mining using Mohr–Coulomb criterion and slip weakening law by Yatao Li, Xuehong Gao, Jianwei Yang, Erhu Bai

“…In this study, we propose an integrated 3-D numerical modeling framework combining the virtual fault (VF), 3-D Mohr–Coulomb criterion model (MC), and slip weakening model (SW) to investigate the dynamics of fault failure and coseismic slip induced by mining activities near faults. …”
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Nanomodified Peek Dental Implants: Bioactive Composites and Surface Modification—A Review by Shariq Najeeb, Zohaib Khurshid, Jukka Pekka Matinlinna, Fahad Siddiqui, Mohammad Zakaria Nassani, Kusai Baroudi

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HUMAN GENES CONTROLLING FEEDING BEHAVIOR OR BODY MASS AND THEIR FUNCTIONAL AND GENOMIC CHARACTERISTICS: A REVIEW by E. V. Ignatieva, D. A. Afonnikov, E. I. Rogaev, N. A. Kolchanov

“…Information on 424 human genes was obtained from scientific publications, OMIM and meta-analysis of GWAS data. Four genes (BDNF, MC4R, PCSK1, and POMC) were confirmed by all three data sources; thus, these genes have the highest priority (No. 1). …”
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Multiple Assessments on the Gamma-Ray Protection Properties of Niobium-Doped Borotellurite Glasses: A Wide Range Investigation Using Monte Carlo Simulations by H. O. Tekin, Fatema T. Ali, Ghada Almisned, Gulfem Susoy, Shams A. M. Issa, Antoaneta Ene, Wiam Elshami, Hesham M. H. Zakaly

“…They have been defined as an attenuator sample between the point isotropic gamma-ray source and the detector in terms of determining their attenuation coefficients. To verify the MC results, attenuation coefficients were then compared with the Phy-X/PSD program data. …”
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EDUCATIONAL INTERVENTION FOR THE CARDIOVASCULAR PREVENTION IN ADOLESCENTS OF SECONDARY BASIC. by Yuri Arnold Domínguez

“…Se utilizaron la Pruebas no paramétricas de Chi cuadrado de Mc Nemar y Mantel- Haenszel. <br /><strong>Resultados</strong>: Se obtuvieron asociaciones estadísticas significativas con un límite de confianza de un 95 %, entre el estado inicial y final de los conocimientos en relación a los factores de riesgos cardiovasculares en el grupo intervenido (p=0,0001), en el grupo de control (p=0,035) y entre el grupo estudio con respecto al grupo control post-intervención (p=0,0001). …”
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Homenaje a Julieta Quilodrán by Viridiana Sosa

“…En la ceremonia participaron Teresa Castro, Robert McCaa, Beatriz Figueroa, Viridiana Sosa, Manuel Ordorica y Silvia Giorguli. …”
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Epidemiological, clinical and imaging profile of Multiple Sclerosis by Làzaro Aurelio Vàzquez Gòmez, Carlos Hidalgo Mesa, Benita Mabel Beltrán González, Yunier Broche Pérez, Ana María Mederos Herrera

“…The epidemiological variables analyzed: sex, age of disease onset, skin color, place of origin; clinical variables: symptoms at the beginning and at present; number of shoots; years of evolution, clinical forms; Imaging variables: number of lesions, location, atrophy or change in signal intensity of the corpus callosum and McDonald's criterion fulfilled.<br /><strong>Results:</strong> there was a higher incidence of females with 80 patients. …”
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