A Direct and Sensitive Method for Determination of 5-Fluorouracil in Colorectal Cancer Cells: Evaluating the Effect of Stromal Cell on Drug Resistance of Cancer Cells by Fengjing Xu, Zhipeng Wang, Xinhua Song, Mengwei Zhang, Lili Cui, Yanping Liu, Hongxia Yan, Shouhong Gao, Yan Liu, Wansheng Chen

“…The preliminary results present that NIH3T3 could enhance the drug resistance of MC38 to 5-FU with a decreased intracellular concentration of 5-FU in MC38, which showed a positive relationship with NIH3T3 number.…”
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A Dutch Fanconi Anemia FANCC Founder Mutation in Canadian Manitoba Mennonites by Yne de Vries, Nikki Lwiwski, Marieke Levitus, Bertus Kuyt, Sara J. Israels, Fré Arwert, Michel Zwaan, Cheryl R. Greenberg, Blanche P. Alter, Hans Joenje, Hanne Meijers-Heijboer

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Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish by Sunil Sharma, Alfredo Rojas, Abhishek Gour, Rosemaria Serradimigni, Connor Leong, Abhisheak Sharma, Subham Dasgupta

“…We dissected eyes and brains from IPP-exposed larvae and conducted 5-mC assessments and mRNA-sequencing. Interestingly, neither of the organs showed differences in 5-mC levels and the brains also did not show substantial transcriptomic effects. …”
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Descriptive retrospective cross-sectional study of rehabilitation care for poststroke users in Québec during the COVID-19 pandemic by Palak Vakil, Perrine Ferré, Johanne Higgins, Louis-David Beaulieu, Marie-Helene Milot, Marie-Hélène Boudrias

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The Relationship between Training and Mental Health among Caregivers of Individuals with Polytrauma by Lillian Flores Stevens, Treven C. Pickett, Kathryn P. Wilder Schaaf, Brent C. Taylor, Amy Gravely, Courtney Harold Van Houtven, Greta Friedemann-Sánchez, Joan M. Griffin

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Mesenchymal Stem Cell-Derived Neuron-Like Cell Transplantation Combined with Electroacupuncture Improves Synaptic Plasticity in Rats with Intracerebral Hemorrhage via mTOR/p70S6K S... by Guoqiang Yang, Jiayi Zhu, Guwen Zhan, Guangbi Fan, Li Deng, Huajun Tang, Xiaoqian Jiang, Bo Chen, Chaoxian Yang

“…Therefore, rat ICH models were established by injecting collagenase and heparin, and the animals were randomly divided into model control (MC), EA stimulation (EA), MSC-derived neuron-like cell transplantation (MSC-dNLCs), and MSC-dNLC transplantation combined with EA stimulation (MSC-dNLCs+EA) groups. …”
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Bilateral prophylactic mastectomy: should we preserve the pectoral fascia? Protocol of a Dutch double blinded, prospective, randomised controlled pilot study with a within-subject... by Cornelis Verhoef, Linetta B Koppert, Marloes E Clarijs, Laurentine S E van Egdom, Dalibor Vasilic, T. van Dalen, C. de Betue, J. Rothbarth, E.V.E. Madsen, L.M. Beelen, M.A.M. Mureau, E.M.L. Corten, A.J.M. Luijsterburg, M.J. Hop, H.M. Zuijdendorp, N.A.S. Posch, C.M.C.A. van Laarhoven, M. de Kraker

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Additive manufacturing of Fe-6.5Si cores with metal-insulator-metal structure via dual-nozzle material extrusion (MEX) technology by Taehyeob Im, Suyeon Kim, Juyong Kim, Minjong Kim, Jonghyeok Ahn, Kwiyoung Lee, Dongju Lee, Jai-Sung Lee, Jongryoul Kim, Caroline Sunyong Lee

“…Despite MC0.2 being approximately three times thicker than the single Fe-6.5Si layer (magnetic core single layer, MCS), a SiO2 insulator used in the cores of MC0.2 and MCS, resulted in comparable eddy current losses at 1 kHz. …”
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Physical development and sociocultural context influences on children’s physical activity by Alessandro Hervaldo Nicolai Ré, Maria Teresa Cattuzzo, David Stodden, Guilherme dos Santos, Albert Lucas Olinto Tertuliano, Carlos Bandeira de Mello Monteiro, Diogo Henrique Constantino Coledam, Anthony David Okely

“…Conclusions: Regardless of CRF or MC, family and sociocultural circumstances influenced PA according to gender. …”
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Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the <em>lethal yellow</em> (A^y) mutation by E. N. Makarova, T. V. Yakovleva, N. Yu. Balyibina, K. O. Baranov, E. I. Denisova, A. D. Dubinina, N. A. Feofanova, N. M. Bazhan

“…Hypothalamic melanocortin 4 receptors (MC4R) regulate energy balance. Mutations in the MC4R gene are the most common cause of monogenic obesity in humans. …”
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mTOR downregulation promotes anti-inflammatory responses via the CCL3-CCR5 axis in hypoxic retinopathy by Tae Kwon Moon, Im Kyeung Kang, Kyoung Jin Lee, Ji Hyun Kim, Hee Jong Kim, A. Reum Han, Ha-Na Woo, Joo Yong Lee, Jun-Sub Choi, Keerang Park, Heuiran Lee

“…It diminished the secretion of CCL3 from rMC1 cells, consequently reducing microglial migration in response to conditioned media from AAV2-shmTOR-treated rMC1 cells. …”
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Evaluation of parent and youth experiences in advisory groups as part of a mental healthcare clinical trial: protocol for a mixed-method study by Maria-Jose Santana, Gina Dimitropoulos, Suneeta Monga, Isabelle J Gagnon, Bruce Wright, Jananee Rasiah, Katrina Hurley, Antonia Stang, Amanda Newton, Stephen Freedman, Jennifer Thull-Freedman, Kassi Prisnie, Yazid N Al Hamarneh, Ellen Louise Lipman, Yaron Finkelstein, Robert Porter, Mohamed Eltorki, Lee Macdonald, Gareth Hopkin, Matthew Prebeg, Margaret Steele, Ahmed Mater, Laurence Katz, Brian Greenfield, Laurie Plotnick

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