Antipsychotic Drugs Reverse MK801-Inhibited Cell Migration and F-actin Condensation by Modulating the Rho Signaling Pathway in B35 Cells by Yi-Chyan Chen, Fu-Ming Tsai, Mao-Liang Chen

“…MK801-induced psychotic symptoms and also the Ras homolog family member A (RhoA) expression and cell division control protein 42 (cdc42) mRNA modulation in the rat brain have been investigated. …”
Get full text

Altered Viral Replication and Cell Responses by Inserting MicroRNA Recognition Element into PB1 in Pandemic Influenza A Virus (H1N1) 2009 by Xiaoyue Shen, Wenkui Sun, Yi Shi, Zheng Xing, Xin Su

“…MicroRNAs (miRNAs) are endogenous noncoding RNAs that spatiotemporally modulate mRNAs in a posttranscriptional manner. Engineering mutant viruses by inserting cell-specific miRNA recognition element (MRE) into viral genome may alter viral infectivity and host responses in vital tissues and organs infected with pandemic influenza A virus (H1N1) 2009 (H1N1pdm). …”
Get full text

Early Sialadenitis After Radioactive Iodine Therapy for Differentiated Thyroid Cancer: Prevalence and Predictors by Ruba Riachy, Nisrine Ghazal, Mohamad B. Haidar, Ahmad Elamine, Mona P. Nasrallah

“…Pretreatment thyroid stimulating hormone (TSH) was greater than 75 mIU/ml in most patients (72.6%). The prevalence of sialadenitis was 20.1% (95% CI (15–27)). …”
Get full text

Recovery of sodium from alumina-extracted fly ash using concentrated sodium carbonate solution by Wang Z., Zheng S., Ma S., Ding J., Wang X.

“…The factors influencing the process were systematically investigated, and the optimal conditions were determined to be: reaction temperature = 180°C, Na2CO3 concentration = 170 g/L, liquid-to-solid ratio = 10 mL/g, and reaction time = 2 h. Under optimal conditions, a low Na2O content of 1.02 wt% of the products, with Na2O extraction rate of 93.79% was achieved. …”
Get full text

Mechanical properties of sedge fiber-reinforced epoxy composites incorporated with graphene oxide by Lucas de Mendonça Neuba, Thuane Teixeira Silva, Lucas Montenegro Reis, Sergio Neves Monteiro, Noan Tonini Simonassi, Luís Cláudio Candido, Artur Camposo Pereira

“…For instance, the group disclosing the best performance in the Izod and Charpy Impact tests revealed values of 108.5 ± 12.22 and 155.51 ± 17.05 J/m, respectively. SEM micrographs revealed that some agglomerations of the GO nano-reinforcement, and interface delamination were drastically reduced, indicating a stronger interface.…”
Get full text

Coupling cobalt single-atom catalyst with recyclable LiBr redox mediator enables stable LiOH-based Li-O2 batteries by Kang Huang, Zhixiu Lu, Shilong Dai, Chunyu Cui, Nam Dong Kim, Huilong Fei

“…Consequently, the fabricated LOB demonstrates fewer side reactions, stable energy efficiency (drop rate of 0.10 % per cycle) and long cycle life (300 cycles at 1000 mA/g) under the ambient atmosphere.‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬…”
Get full text

Design of Dielectric Elastomer Actuator and Its Application in Flexible Gripper by Xiaoyu Meng, Jiaqing Xie, Haoran Pang, Wenchao Wei, Jiping Niu, Mingqiang Zhu, Fang Gu, Xiaohuan Fan, Haiyan Fan

“…The elliptical DEA can produce a bending deformation of 40° and an output force of 37.2 mN at a voltage of 24 kV. The three-finger flexible gripper composed of an elliptical DEA can realize the grasping of a paper cup.…”
Get full text

Chemical Composition, Antioxidant Activity, and Antifungal Effects of Essential Oil from Laurus nobilis L. Flowers Growing in Morocco by Ibrahim Mssillou, Abdelkrim Agour, Asmae El Ghouizi, Noureddine Hamamouch, Badiaa Lyoussi, Elhoussine Derwich

“…The results indicated that essential oil from L. nobilis flowers exhibited significant antifungal activity against the tested fungal strains with minimum inhibitory concentrations (MICs) ranging from 0.05 to 0.46 mg/mL. The essential oil of L. nobilis also exhibited strong total antioxidant capacity (TAC) as indicated by its ability to scavenge free radical DPPH. …”
Get full text

Assessment of the Personal Dose Received by School Children due to PM10 Air Pollution in Lisbon by Eleftheria Chalvatzaki, Sofia Eirini Chatoutsidou, Vânia Martins, Tiago Faria, Evangelia Diapouli, Manousos Manousakas, Susana Marta Almeida, Konstantinos Eleftheriadis, Mihalis Lazaridis

“…Hence, this study applied a dosimetry model (ExDoM2) to predict the personal dose received by students in five primary schools in Lisbon, Portugal. …”
Get full text

CRISPR/Cas9-mediated genomic insertion of functional genes into Lactiplantibacillus plantarum WCFS1 by Kamilla Wiull, Lisa K. Haugen, Vincent G. H. Eijsink, Geir Mathiesen

“…We demonstrate that the system enables efficient insertion of expression cassettes for both inducible and constitutive production of a fluorescent reporter protein, mCherry, and for inducible production of the receptor-binding domain (RBD) of the SARS-CoV-2 virus. …”
Get full text

Smad4 deficiency in hepatocytes attenuates NAFLD progression via inhibition of lipogenesis and macrophage polarization by Wei Yang, Xuanxuan Yan, Rui Chen, Xin Xin, Shuang Ge, Yongxiang Zhao, Xinlong Yan, Jinhua Zhang

“…Furthermore, targeting CXCL1 using CXCR2 inhibitors diminished hepatocyte lipogenesis and inhibited the polarization of M1-type macrophages. Collectively, these results suggested that Smad4 plays a vital role in exacerbating NAFLD and may be a promising candidate for anti-NAFLD therapy.…”
Get full text

Influence of Treadmill Speed and Perturbation Intensity on Selection of Balancing Strategies during Slow Walking Perturbed in the Frontal Plane by Zlatko Matjačić, Matjaž Zadravec, Andrej Olenšek

“…Ten healthy individuals underwent an experimental protocol whereby a set of perturbations directed inward (medially to a stance leg) and outward (laterally to a stance leg) of three intensities (F1=5%, F2=10%, and F3=15% of body weight), applied at three instances of a stance phase, were delivered in random order to the pelvis using a balance assessment robot while walking on a treadmill at three walking speeds (S1=0.4, S2=0.6, and S3=0.8 m/s). We analyzed the peak center of mass displacements; step length, step width, and step times; and the lateral component of ground reaction force for perturbations that were delivered at the beginning of the gait cycle. …”
Get full text

Optimization of anthracene biodegradation by indigenous Trichoderma lixii and Talaromyces pinophilus using response surface methodology by Samson O. Egbewale, Ajit Kumar, Mduduzi P. Mokoena, Ademola O. Olaniran

“…Acute toxicity tests showed that the degradation media toxicity reduced as evidenced by increased in survival rate (log CFU/mL) of Vibrio parahaemolyticus after 6 h exposure. …”
Get full text

Genetic diversity of wild stone fruit species: specific aspects of <i>ex situ</i> conservation by G. V. Eremin, V. G. Eremin, I. S. Chepinoga, T. A. Gasanova

“…The recommended planting schemes (2.5–4.0 × 0.5–1.0 m) significantly reduce the area occupied by the same number of plants in conventional cultivation patterns and cut down power and labor inputs into technological practices.…”
Get full text

Expansion of Circulating T Follicular Helper Cells in Children with Acute Henoch-Schönlein Purpura by Jue Xie, Yan Liu, Lei Wang, Guoxiang Ruan, Huiming Yuan, Hong Fang, Jianyong Wu, Dawei Cui

“…A positive correlation was observed between the frequencies of circulating ICOS+CXCR5+CD4+TFH cells and the serum IL-21 or IgA levels of acute HSP children, respectively. Additionally, the mRNA expression levels of interleukin- (IL-) 21, IL-6, and transcriptional factors (B-cell lymphoma-6, Bcl-6) were also significantly increased in peripheral blood from acute HSP children compared to HCs. …”
Get full text

Risk Mitigation and Construction Control for Effective Underwater Recovery of an EPB Shield: A Case Study of the First Metro Tunnel in Tel Aviv by Weiqiang Qi, Zhiyong Yang, Yusheng Jiang, Zhiyong Liu, Yinxin Guo, Xing Yang

“…Furthermore, according to the actual situation on site, filling the shaft with water to 1 m above the water level in the strata can prevent the fine sand from percolating into the shaft. …”
Get full text

Current molecular understanding of central nervous system schwannomas by Takahiro Tsuchiya, Satoru Miyawaki, Yu Teranishi, Kenta Ohara, Yudai Hirano, Shotaro Ogawa, Seiei Torazawa, Yu Sakai, Hiroki Hongo, Hideaki Ono, Nobuhito Saito

“…Merlin, the protein encoded by NF2, is integral to several signaling pathways, including Ras/Raf/MEK/ERK, PI3K/Akt/mTORC1, Wnt/β-catenin, and the Hippo pathway. Main body Recent research has also uncovered novel genetic alterations, such as the SH3PXD2A::HTRA1 fusion gene, VGLL-fusions in intraparenchymal CNS schwannomas, and the SOX10 mutation particularly in non-vestibular cranial nerve schwannomas. …”
Get full text

Factors affecting DH plants <i>in vitro</i> production from microspores of European radish by E. V. Kozar, E. A. Domblides, A. V. Soldatenko

“…At regeneration and tiller stage it is advisable to add 1 mg/mL of benzylaminopurine and 0.1 mg/L of gibberellic acid to the medium, and rotting of micro-sprouts is performed with the use of hormone-free medium. …”
Get full text

Extended-Spectrum β-Lactamase (ESBL) Genotypes among Multidrug-Resistant Uropathogenic Escherichia coli Clinical Isolates from a Teaching Hospital of Nepal by Roshan Pandit, Balkrishna Awal, Sumesh Shreekhanda Shrestha, Govardhan Joshi, Basista Prasad Rijal, Narayan Prasad Parajuli

“…Among MDR E. coli isolates, 40.3% were producing extended-spectrum β-lactamases (ESBLs). bla-TEM (83.8%), bla-CTX-M (66.1%), and bla-SHV (4.8%) were common ESBL genotypes. …”
Get full text

Effects of Different Inspiratory Muscle Training Protocols on Exercise Capacity, Respiratory Muscle Strength, and Health-Related Quality of Life in Patients with Hypertension by İrem Hüzmeli, Nihan Katayıfçı, Fatih Yalçın, Esra Doğru Hüzmeli

“…Forty-five patients (58.37 ± 8.53 y, 7F/38M) with HT received IMT (7 days/8 weeks) by POWERbreathe® Classic LR device and were randomized to control group (CG, 10% maximal inspiratory pressure (MIP), n: 15), low-load group (LLG, 30% MIP), and high-load group (HLG, %50 MIP). …”
Get full text