Cytotoxic Constituents from the Rhizomes of Curcuma zedoaria by Omer Abdalla Ahmed Hamdi, Syarifah Nur Syed Abdul Rahman, Khalijah Awang, Norhanom Abdul Wahab, Chung Yeng Looi, Noel Francis Thomas, Sri Nurestri Abd Malek

“…Curcumenone (3) and curcumenol (5) displayed strong antiproliferative activity (IC50=8.3±1.0 and 9.3±0.3 μg/mL, resp.) and were found to induce apoptotic cell death on MCF-7 cells using phase contrast and Hoechst 33342/PI double-staining assay. …”
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Investigating the role of intratumoral Streptococcus mitis in gastric cancer progression: insights into tumor microenvironment by Ping Yang, Gaoli Liang, Yangyue Ni, Xiaojie Chu, Xiaoshan Zhang, Zhongyu Wang, Adeel Khan, Fangfang Jin, Han Shen, Miao Li, Zhipeng Xu

“…Based on the results of in vivo experiments and intratumoral microbiota analysis, we found that Streptococcus mitis can inhibit gastric cancer progression via suppressing M2 macrophage polarization and infiltration, as well as altering the intratumoral microbial community. …”
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Pathway Analysis of Metabolic Syndrome Using a Genome-Wide Association Study of Korea Associated Resource (KARE) Cohorts by Unjin Shim, Han-Na Kim, Yeon-Ah Sung, Hyung-Lae Kim

“…Cohort data from the Korea Associated Resource (KARE) was used for analysis, which include 8,842 individuals (age, 52.2 ± 8.9 years; body mass index, 24.6 ± 3.2 kg/m2). A total of 312,121 autosomal SNPs were obtained after quality control. …”
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Identification of hub genes, non-coding RNAs and pathways in Renal cell carcinoma (RCC): A comprehensive in silico study by Ahmad Golestanifar, Hengameh Khedri, Parisa Noorabadi, Mohammadreza Saberiyan

“…Using high-throughput sequencing datasets from the Gene Expression Omnibus (GEO), we identified differentially expressed mRNAs (DEMs), miRNAs (DEMIs), and circRNAs (DECs) in KIRC samples compared to normal kidney tissues. …”
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SP-YOLO: A Real-Time and Efficient Multi-Scale Model for Pest Detection in Sugar Beet Fields by Ke Tang, Yurong Qian, Hualong Dong, Yuning Huang, Yi Lu, Palidan Tuerxun, Qin Li

“…In comparison with the original YOLO11 model, SP-YOLO shows a 4.9% improvement in mean average precision (mAP@50), a 9.9% increase in precision, and a 1.3% rise in average recall. …”
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Meso Hybridized Silk Fibroin Watchband for Wearable Biopotential Sensing and AI Gesture Signaling by Xiao Wang, Changsheng Lu, Zerong Jiang, Guangwei Shao, Jingzhe Cao, Xiang Yang Liu

“…The use of Mo‐Au FMs in warp‐knitted patterns results in high SNR (43.22 dB), high sensitivity (44.43 mV/kg), and significant motion noise reduction due to the pattern's elastic deformability and skin‐gripping properties. …”
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A study on climate change impacts using lumped versus distributed hydrological models in a semi-arid basin by Farahnaz Baharvand, Ali Reza Massah Bavani, Mohammad Mahdavi, Massoud Goodarzi

“…By analyzing the models, finally, the three best models, including GFDL-CM3, CNRM-CM5 and NorESM1-M models, which reproduce the climatic behavior of monthly temperature and precipitation values, were selected. …”
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Worker’s Personal Exposure to PM0.1 and PM4 Titanium Dioxide Nanomaterials during Packaging by Ichiro Higashikubo, Rizki Andre Handika, Toshihiro Kawamoto, Hidesuke Shimizu, Thunyapat Thongyen, Suthida Piriyakarnsakul, Amin Muhammad, Mitsuhiko Hata, Masami Furuuchi

“…The maximum PM0.1 concentration (31.3 µg m–3) occurred in a powder filling booth without air ventilation. …”
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Perbedaan Kadar Aldosteron dan Tekanan Darah pada Akseptor KB Pil Kombinasi Berdasarkan Lama Pemakaian Kontrasepsi by Anjelina Puspita Sari, Eti Yerizel, Joserizal Serudji

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Peripheral nerve regeneration using a bioresorbable silk fibroin-based artificial nerve conduit fabricated via a novel freeze–thaw process by Tomoki Matsuo, Hiroo Kimura, Takayuki Nishijima, Yasuhiro Kiyota, Taku Suzuki, Narihito Nagoshi, Shinsuke Shibata, Tomoko Shindo, Nobuko Moritoki, Makoto Sasaki, Sarara Noguchi, Yasushi Tamada, Masaya Nakamura, Takuji Iwamoto

“…Histological analyses indicated that vascularization and M2 macrophage recruitment were pronounced inside the SFC. …”
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Establishment of predictive models for head loss and filtration efficiency of pontoon mesh rotary filter based on dimension analysis by Zhen Jin, Lingwei Chen, Qiao Li, Mahemujiang Aihemaiti, Youwei Jiang, Hongfei Tao

“…In addition, the head loss under this condition was 0.281 m, and the filtration efficiency was 84.01%. These results could serve as a reference for the further optimization and application of the pontoon mesh rotary filter, while also enriching the hydraulic performance and filtration performance of the pre-pump filter.…”
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Small RNA sequencing highlights potential functions of tsRNAs in regulating pyroptosis in trigeminal neuralgia by Mizhen Qiu, Fei Zeng, Yi Yan, Mu Xu, Xuexue Zhang, Zhijian Wang, Yutong Wang, Daying Zhang, Shibiao Chen

“…KEGG pathway enrichment showed that DEtsRNAs were mainly involved in pyroptosis-related pathways, such as MAPK, ErbB, and mTOR signaling pathways. RT-qPCR showed that pyroptosis-related DEtsRNAs of tsRNA003489, tsRNA001840, and tsRNA003424 were downregulated in TN. …”
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Bifunctional copper ion/melittin incorporated hydrogel with antimicrobial and antioxidant capabilities for infected skin wound healing by Jun Yao, Xiao Li, Minjie Lin, Zhuoqi Han, Xiaonan Wang, Jingjing Guo, Bing Wu, Jiajie Xia

“…Additionally, the SA@Cu-MEL hydrogel reduces inflammatory responses, promotes macrophage polarisation to the anti-inflammatory M2 type, and facilitates NIH cell proliferation and migration. …”
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Odontogenic differentiation of dental pulp stem cells by glycogen synthase kinase-3β inhibitory peptides by Vidhyashree Rajasekar, Mohamed Mahmoud Abdalla, Mohammed S. Basbrain, Prasanna Neelakantan, Cynthia KY Yiu

“…The differentiation of hDPSCs following peptide treatment was determined using the alkaline phosphatase assay (ALP), calcium mineralization (alizarin red staining), and quantification of mRNA expression of differentiation markers via quantitative real-time polymerase chain reaction. …”
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PSMA antibody, humanized PSMA.CAR10.3, or Cetuximab increases prostate cancer localization of NF-κB p50-deficient immature myeloid cells (p50-IMC) and phagocytosis by their macroph... by Mohammad A. Alzubi, Theresa Barberi, Alan D. Friedman

“…Additionally, we find that PSMA Ab, EGFR Ab, or PSMA.CAR10.3 increase in vitro phagocytosis of Myc-CaP cells expressing PSMA or EGFR by p50-IMC-derived macrophages, including in M2-promoting IL-4, which is a component of the immune-suppressive tumor microenvironment. …”
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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression by Michala Prause, Christopher Michael Mayer, Caroline Brorsson, Klaus Stensgaard Frederiksen, Nils Billestrup, Joachim Størling, Thomas Mandrup-Poulsen

“…INS-1 cells express JNK1α1, JNK1α2, JNK1β1, JNK1β2, JNK2α1, JNK2α2, JNK3α1, and JNK3α2 mRNA isoform transcripts translating into 46 and 54 kDa isoform JNK proteins. …”
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Biological properties of Moringa oleifera: A systematic review of the last decade [version 2; peer review: 2 approved, 1 approved with reservations] by Andrea Catalina Gómez, Javier Andrés Soto, C. A. Zuniga-Gonzalez, Karen Shirley Molina, Andrea Natalia Barreto, Maryeli Vásquez

“…On the other hand, the antimicrobial potential of M. oleifera was also evidenced, especially against multidrug-resistant strains. …”
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Assessing Macrophyte and Ecosystem Service Changes in Shallow Eutrophic Coastal Waters Using Remote Sensing Methods by Johanna Schumacher, David Horn, Gabriela Escobar-Sánchez, Greta Markfort, Gerald Schernewski, Mario von Weber

“…Our aerial drone detected macrophytes up to a depth of 3 m that could be integrated into the existing macrophyte monitoring scheme of the Water Framework Directive. …”
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Immunoglobulin G4-related disease with pleural involvement in an 80-year-old female patient: A case report and literature review by Liying Zhang, Li Mo

“…Methods: We report a case of IgG4-RD involving the pleura in an 80-year-old woman with a weight of 62 kg and a body mass index (BMI) of 23.2 kg/m2. Additionally, we reviewed pleural biopsy-confirmed IgG4-RD cases in the PubMed, Scopus, Web of Science, Embase, and Science Direct databases. …”
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Assessing the Clinical and Functional Status of COPD Patients Using Speech Analysis During and After Exacerbation by Mayr W, Triantafyllopoulos A, Batliner A, Schuller BW, Berghaus TM

“…Wolfgang Mayr,1,* Andreas Triantafyllopoulos,2,3,* Anton Batliner,2,3 Björn W Schuller,2– 5 Thomas M Berghaus1,6 1Department of Cardiology, Respiratory Medicine and Intensive Care, University Hospital Augsburg, Augsburg, Germany; 2Chair of Health Informatics (CHI), Department of Clinical Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; 3Munich Center for Machine Learning (MCML), Munich, Germany; 4Group on Language Audio, & Music (GLAM), Imperial College, London, UK; 5Munich Data Science Institute (MDSI), Munich, Germany; 6Medical Faculty, Ludwig Maximilians University of Munich, Munich, Germany*These authors contributed equally to this workCorrespondence: Wolfgang Mayr, Department of Cardiology, Respiratory Medicine and Intensive Care, University Hospital Augsburg, Stenglinstrasse 2, Augsburg, D-86156, Germany, Email wolfgang.mayr@uk-augsburg.de Andreas Triantafyllopoulos, Chair of Health Informatics, Department of Clinical Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Straße 22, Munich, 81675, Germany, Email andreas.triantafyllopoulos@tum.deBackground: Chronic obstructive pulmonary disease (COPD) affects breathing, speech production, and coughing. …”
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