The infiltration risk prediction models by logistic regression for ground-glass pulmonary nodules: a systematic review and meta-analysis by Mengqian Li, Mengqian Li, Xiaomei Zhang, Yuxin Lai, Yunlong Sun, Tianshu Yang, Xinlei Tan

“…The meta-analysis showed the following: average CT value (MD = 75.57 HU, 95%CI: 44.40–106.75), maximum diameter (MD = 4.99 mm, 95%CI: 4.22–5.77), vascular convergence sign (OR = 11.16, 95%CI: 6.71–18.56), lobulation sign (OR = 3.80, 95%CI: 1.59–9.09), average diameter (MD = 4.46 mm, 95%CI: 3.44–5.48), maximum CT value (MD = 112.52 HU, 95%CI: 8.08–216.96), spiculation sign (OR = 4.46, 95%CI: 2.03–9.81), volume (MD = 1,069.37 mm3, 95%CI: 1,025.75–1,112.99), vacuole sign (OR = 6.15, 95%CI: 2.70–14.01), CTR ≥0.5 (OR = 7.24, 95%CI: 3.35–15.65), vascular type [types III and IV] (OR = 13.62, 95%CI: 8.85–20.94), pleural indentation (OR = 6.92, 95%CI: 2.69–17.82), age (MD = 4.18years, 95%CI: 1.70–6.65), and mGGN (OR = 3.62, 95%CI: 2.36–5.56) were risk factors for infiltration of ground-glass nodules. …”
Get full text

Clinical practice of one-lung ventilation in mainland China: a nationwide questionnaire survey by Hong-jin Liu, Yong Lin, Wang Li, Hai Yang, Wen-yue Kang, Pei-lei Guo, Xiao-hui Guo, Ning-ning Cheng, Jie-chao Tan, Yi-na He, Si-si Chen, Yan Mu, Xian-wen Liu, Hui Zhang, Mei-fang Chen

“…Volume control ventilation mode, 4 to 6 mL per kilogram of predictive body weight, pure oxygen inspiration, and a low-level positive end-expiratory pressure ≤ 5 cm H2O were the most popular ventilation parameters. …”
Get full text

Intranasal Delivery of miR-146a Mimics Delayed Seizure Onset in the Lithium-Pilocarpine Mouse Model by Hua Tao, Jianghao Zhao, Tingting Liu, Yujie Cai, Xu Zhou, Huaijie Xing, Yan Wang, Mingkang Yin, Wangtao Zhong, Zhou Liu, Keshen Li, Bin Zhao, Haihong Zhou, Lili Cui

“…While the relative miR-146a levels significantly increased, the expression of its target mRNAs (IRAK-1 and TRAF-6) and typical inflammatory modulators (NF-κB, TNF-α, IL-1β, and IL-6) decreased, supporting an anti-inflammatory role of miR-146a via the TLR pathway. …”
Get full text

Depression and Temporal Lobe Epilepsy: Expression Pattern of Calbindin Immunoreactivity in Hippocampal Dentate Gyrus of Patients Who Underwent Epilepsy Surgery with and without Com... by Luciana D’Alessio, Hector Konopka, Patricia Solís, Laura Scévola, Mónica Fernandez Lima, Claudio Nuñez, Eduardo Seoane, Silvia Oddo, Silvia Kochen

“…Depression was associated with a higher % of cells with the CB dendritic expression (CB-sprouted cells) (F1,20=11.81, p=0.003, hp2=0.37), a higher CB+ area (μm2) (F1,20=5.33, p=0.032, hp2=0.21), and a higher optical density (F1,20=15.09, p=0.001, hp2=0.43) (two-way ANOVA). …”
Get full text

Behavior Changes in Quinpirole Obsessive-Compulsive Disorder Rats Treated with 6-Hydroxydopamine and the Corresponding Dopaminergic Compulsive Loop Mechanism by Haowen Zheng, Rui He, Yang Ming, Haiping He, Wei Wang, Ligang Chen, Feilong Gong

“…Methods: A total of 52 male Sprague Dawley (SD) rats were exposed to either saline (1 mL/kg, NS group, n = 6) or quinpirole (QNP, dopamine D2-agonist, 0.5 mg/kg, n = 46) twice weekly for 5 weeks. …”
Get full text

Molecular hydrogen reduces dermatitis-induced itch, diabetic itch and cholestatic itch by inhibiting spinal oxidative stress and synaptic plasticity via SIRT1-β-catenin pathway in... by Linlin Zhang, Fangshi Zhao, Yize Li, Zhenhua Song, Lingyue Hu, Yuanjie Li, Rui Zhang, Yonghao Yu, Guolin Wang, Chunyan Wang

“…Herein, we strikingly report that both hydrogen gas (2 %) inhalation and hydrogen-rich saline (5 mL/kg, intraperitoneal) injection prevent and alleviate persistent dermatitis-induced itch, diabetic itch and cholestatic itch. …”
Get full text

Reproducibility of indirect persistent inward current indicators with neuromuscular electrical stimulation by Timothée Popesco, Davide D'Amato Brunetta, Stefano Pata, Nicolas Place

“…Scientific Reports, 11(1), 6399. https://doi.org/10.1038/s41598-021-85645-0 Heckman, C. J., & Enoka, R. M. (2012). Motor unit. Comprehensive Physiology, 2(4), 2629–2682. https://doi.org/10.1002/cphy.c100087 Mesquita, R. …”
Get full text

Bio-carbon composite for supercapacitor electrodes: Harnessing hydrochar frameworks and bio-tar polymerization by Jixiu Jia, Yuxuan Sun, Lili Huo, Lixin Zhao, Ziyun Liu, Zhidan Liu, Kang Kang, Shuaishuai Zhang, Teng Xie, Yanan Zhao, Zonglu Yao

“…And it also showed a maximum specific surface area of 2714.27 m2/g, with a mesopore ratio of 68.79 % at an activation temperature of 800 °C. …”
Get full text

High-Resolution Satellite Reveals the Methane Emissions from China’s Coal Mines by Xingyu Li, Tianhai Cheng, Hao Zhu, Xiaotong Ye, Donghao Fan, Tao Tang, Haoran Tong, Shizhe Yin, Jingyu Xiong

“…With a spatial resolution of 60 m and spectral channels from 381 to 2493 nm, the EMIT satellite can finely characterize facility-level methane plumes. …”
Get full text

Serum hsa-miR-22-3p, hsa-miR-885-5p, Lipase-to-Amylase Ratio, C-Reactive Protein, CA19-9, and Neutrophil-to-Lymphocyte Ratio as Prognostic Factors in Advanced Pancreatic Ductal Ade... by Jakub Wnuk, Dorota Hudy, Joanna Katarzyna Strzelczyk, Łukasz Michalecki, Kamil Dybek, Iwona Gisterek-Grocholska

“…For NLR, CRP and CA19-9 thresholds were determined using ROC analysis (6.63, 24.7 mg/L and 4691 U/mL, respectively). Cox’s F test for overall survival showed statistically significant differences between groups (<i>p</i> = 0.002 for NLR, <i>p</i> = 0.007 for CRP and <i>p</i> = 0.007 for CA19-9). …”
Get full text

INdependenT prEscribinG in community phaRmAcy; whaT works for whom, why and in what circumstancEs (INTEGRATE): Realist review study protocol [version 1; peer review: 2 approved] by Andrew Sturrock, Tony Kelly, Vivienne Hibberd, Ian Maidment, Ola Amr Abdelfatah, Nia Roberts, Ellen Schafheutle, Andrea Hilton, Keith Holden, Geof Wong, Nick Haddington, Lesley Scott

Get full text

2′-Hydroxycinnamaldehyde induces ROS-mediated apoptosis in cancer cells by targeting PRX1 and PRX2 by Yae Jin Yoon, Yu-Jin Lee, Jiyeon Choi, Seung-Wook Chi, Sangku Lee, Kyung Chan Park, Byoung-Mog Kwon, Dong Cho Han

“…Treatment of SW620 cancer cells transfected by control vector with 20 μM HCA increased ROS levels by 5.2-fold compared to DMSO-treated cells. …”
Get full text

Influence of preoperative variables on the 3-month functional outcomes of the Vivity extended depth-of-focus intraocular lens: a prospective case series by Giacomo Savini, Alice Galzignato, Catarina P. Coutinho, Jinhai Huang, Yue Wu, Piero Barboni, João Mendanha Dias, Filomena J. Ribeiro, Domenico Schiano-Lomoriello

“…Three months postoperatively, manifest refraction, monocular and binocular uncorrected and corrected visual acuity at 4 m, 66 cm and 40 cm, binocular defocus curve, binocular contrast sensitivity, halometry and Strehl ratio were measured. …”
Get full text

A Test-Retest Study of Single- and Multi-Delay pCASL for Choroid Plexus Perfusion Imaging in Healthy Subjects Aged 19 to 87 Years by Zixuan Liu, Qinyang Shou, Kay Jann, Chenyang Zhao, Danny JJ Wang, Xingfeng Shao

“…Additionally, ChP volume (mean ± std = 1.72± 0.85 ml) increased (p < 0.01) and ChP perfusion (43.07±14.18 mL/100 g/min) decreased (p = 0.04) with age. These findings underscore the robustness of multi-delay ASL with model-fitting quantification in assessing ChP perfusion, making it the preferred method for accurate CBF and ATT estimation, particularly in regions with prolonged transit time such as ChP.…”
Get full text

Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development by Zhijie Hu, Yuqi Zhang, Renfei Cai, Qiuju Chen, Haiyan Guo, Danjun Li, Weidong Lin, Hongxi He, Haibo Wu, Yali Liu, Bin Li, Qianwen Xi, Hongyuan Gao, Jian Zhang, Qifeng Lyu, Yanping Kuang, Xuefeng Lu

“…Additionally, our research revealed that OAD influences the expression of multitude of genes at the 2‐pronuclear (2PN) stage, with the Mos gene playing a pivotal role in early embryonic arrest. The injection of Mos mRNA can mitigate this arrest. To our knowledge, this is the first study to show that sperm‐related OAD affects gene expression at the 2PN stage and elucidate how AOA overcomes male factor‐derived embryonic arrest, enabling successful pregnancies and live births.…”
Get full text

Characterization of dynamic stall of a wind turbine airfoil with a high Reynolds number by H. R. Kim, J. A. Printezis, J. D. Ahrens, J. R. Seume, L. Wein

“…<p>This study shows an extensive analysis of dynamic stall on wind turbine airfoils, preparing for the development of a reduced-order model applicable to thick airfoils (<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M1" display="inline" overflow="scroll" dspmath="mathml"><mrow><mi>t</mi><mo>/</mo><mi>c</mi><mo>&gt;</mo><mn mathvariant="normal">0.21</mn></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="53pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="aa10b0f7589f34c39cbb1ba9f034335d"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="wes-10-161-2025-ie00001.svg" width="53pt" height="14pt" src="wes-10-161-2025-ie00001.png"/></svg:svg></span></span>) in the future. …”
Get full text

Extensive Atrophic Gastritis Increases Intraduodenal Hydrogen Gas by Yoshihisa Urita, Toshiyasu Watanabe, Tadashi Maeda, Tomohiro Arita, Yosuke Sasaki, Takamasa Ishii, Tatsuhiro Yamamoto, Akiro Kugahara, Asuka Nakayama, Makie Nanami, Kaoru Domon, Susumu Ishihara, Hirohito Kato, Kazuo Hike, Norikok Hara, Shuji Watanabe, Kazushige Nakanishi, Motonobu Sugimoto, Kazumasa Miki

“…At the time of endoscopic examination, we intubated the stomach and the descending part of the duodenum without inflation by air, and 20 mL of intraluminal gas samples of both sites was collected through the biopsy channel. …”
Get full text

Kefir Prevents Adipose Tissue Growth Through the Induction of Apoptotic Elements in High-Fructose Corn Syrup-Fed Rats by Esra Aslan, Gokhan Sadi, Hilal Guzel, Cigdem Karaca, Omer Adil Korkmaz, Mine Kanat Pektas, Mehmet Celegen, Tugce Aladag, Seyma Oncu, Mehmet Bilgehan Pektas

“…HFCS (20%, w/v ) was given in drinking water and kefir (1 mL/100 g body weight) by gastric gavage daily for 8 weeks. …”
Get full text

Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model by Caroline Schoenherr, Caroline Schoenherr, Stefan Pietzsch, Stefan Pietzsch, Cristina Barca, Franziska E. Müller, Frauke S. Bahr, Martina Kasten, Andre Zeug, Sergej Erschow, Christine S. Falk, Evgeni Ponimaskin, James T. Thackeray, Denise Hilfiker-Kleiner, Denise Hilfiker-Kleiner, Melanie Ricke-Hoch

“…Although anti-PD-L1 treatment was associated with increased troponin I type 3 cardiac (TNNI3) blood levels, cardiac mRNA expression of macrophage markers and elevated cardiac levels of secreted inflammatory factors compared to Ctrl treatment, both groups showed a comparable density of inflammatory cells in the heart (using CXCR4-ligand 68Ga-Pentixafor in PET-CT and immunohistochemistry). …”
Get full text

Associations between exposure to volatile organic compounds with obesity in adults by Runmiao Wu, Lei Jia, Xu Zhu, Gongchang Guan, Junkui Wang, Rutai Hui, Meijuan Ma, Zhao Zhao, Hui Pang, Ling Zhu

“…The median BMI was 27.7 (24.2, 32.4) kg/m2, and the median waist circumference was 98.0 (87.3, 109.0) cm. …”
Get full text