The effect of a comprehensive intervention on anthropometric indices, dietary intake, and physical activity of adolescent boys with overweight by Fatemeh Sadat Hashemi Javaheri, Zahra Mousavi, Saeideh Mohammadi, Arezoo Amjadi, Khadijeh Abbasi Mobarakeh, Seyedeh Hayedeh Mousavi Shalmani, Mahdieh Torkaman, Masoomeh Alsadat Mirshafaei, Sara Khoshdooz, Zahra Saeedirad, Naser Kalantari, Parmis Mirzaei, Saeid Doaei, Nastaran Keshavarz Mohammadi, Maryam Gholamalizadeh

“…The intervention resulted in a significant increase in physical activity parameters including distance (3501 ± 287 vs. 614 ± 56 m/d), duration (203 ± 35 vs. 72 ± 10 min/d), and calorie expenditure (359.24 ± 62.4 vs. 46.74 ± 7.5 kcal/d) in the intervention group compared to the control group (P < 0.01). …”
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Investigation of Novel Aronia Bioactive Fraction-Alginic Acid Nanocomplex on the Enhanced Modulation of Neuroinflammation and Inhibition of Aβ Aggregation by Bong-Keun Jang, Soo Jung Shin, Hyun Ha Park, Vijay Kumar, Yong Ho Park, Jeom-Yong Kim, Hye-Yeon Kang, Sunyoung Park, Youngsun Kwon, Sang-Eun Shin, Minho Moon, Beom-Jin Lee

“…Conclusions: Our data indicate that AANCPs are more stable than ABFs and effective for cognitive disorders and neuroinflammation via modulation of M2 microglial polarization.…”
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Broad Diversity of Fungi in Hospital Water by Máira Gazzola Arroyo, Adriano Menis Ferreira, Oleci Pereira Frota, Natalia Seron Brizzotti-Mazuchi, Jacqueline Tanury Macruz Peresi, Marcelo Alessandro Rigotti, Carlos Eduardo Macedo, Alvaro Francisco Lopes de Sousa, Denise de Andrade, Margarete Teresa Gottardo de Almeida

“…Methods. Water samples (100 mL) were collected from taps (n = 74) and water purifiers (n = 14) in different locations in a university hospital. …”
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5-HT7R enhances neuroimmune resilience and alleviates meningitis by promoting CCR5 ubiquitination by Zhenfang Gao, Yang Gao, Yuxiang Li, Jie Zhou, Ge Li, Shun Xie, Ruiyan Jia, Lanying Wang, Ziying Jiang, Meng Liang, Chunxiao Du, Yaqiong Chen, Yinji Liu, Lin Du, Cong Wang, Shuaijie Dou, Zhonglin Lv, Lubin Wang, Renxi Wang, Beifen Shen, Zhiding Wang, Yunfeng Li, Gencheng Han

“…Mechanistically, the Fluoxetine-5-HT7R axis induces proteasome-dependent degradation of CCR5 via mTOR signaling, and then recruits STUB1, an E3 ubiquitin ligase, to initiate K48-linked polyubiquitination of CCR5 at K138 and K322, promotes its proteasomal degradation. …”
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Effect of differences in vascular anatomy on surgical outcomes of left pancreatectomy: a retrospective study by Masahiro Fukada, Noriki Mitsui, Takeshi Horaguchi, Yuji Hatanaka, Itaru Yasufuku, Yuta Sato, Jesse Yu Tajima, Shigeru Kiyama, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi

“…In open-LP cases, high body mass index (> 24 kg/m2; OR 7.24; 95% CI 1.89–36.34; p < 0.01), tumor location (pancreatic body; OR 6.89; 95% CI 1.79–33.79; p < 0.01), and the SpA type (type 2; OR 5.86; 95% CI 1.72–24.65; p < 0.01) showed significant association with prolonged operations. …”
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The effect of prednisolone ingestion and acute exercise on lipocalin-2 and its variants in young men: a pilot randomised crossover study by Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

“…In a randomised crossover design, nine young healthy men (aged 27.8 ± 4.9 years; BMI 24.4 ± 2.4 kg/m2) completed 30 min of high-intensity aerobic exercise (90–95% heart rate reserve) after glucocorticoid or placebo ingestion. …”
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Характеристика яловичини, отриманої від бугайців української чорно-рябої молочної породи за різного покриву туш жировою тканиною... by Крук О.П., Угнівенко А.М.

“…Згідно з класифікацією JMGA (2000), оцінювали колір м’язової та жирової тканин за використання шкали від 1 до 7 балів, а мармуровість m. longissimus dorsi – між 12-м та 13-м ребром – за шкалою від 1 до 12 балів. …”
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Antimycobacterial Activity, Synergism, and Mechanism of Action Evaluation of Novel Polycyclic Amines against Mycobacterium tuberculosis by Erika Kapp, Jacques Joubert, Samantha L. Sampson, Digby F. Warner, Ronnett Seldon, Audrey Jordaan, Margaretha de Vos, Rajan Sharma, Sarel F. Malan

“…The most potent antimycobacterial demonstrated a minimum inhibitory concentration (MIC99) of 9.6 μM against Mycobacterium tuberculosis H37Rv. Genotoxicity and inhibition of the cytochrome bc1 respiratory complex were excluded as mechanisms of action for all compounds. …”
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Combinatorial immunotherapy with anti-ROR1 CAR NK cells and an IL-21 secreting oncolytic virus against neuroblastoma by Yaya Chu, Meijuan Tian, Uksha Saini, Jessica Ayala-Cuesta, Kayleigh Klose, Alyssa S. Mendelowitz, Keira Foley, Mehmet F. Ozkaynak, Wen Luo, Timothy P. Cripe, Dean A. Lee, Kevin A. Cassady, Mitchell S. Cairo

“…In the current study, we successfully engineered ex-vivo-expanded NK cells to express a chimeric antigen receptor (CAR) against ROR1 using mRNA electroporation and investigated the efficacy of anti-ROR1-CAR-NK cells combined with C021 in targeting ROR1+ NB. …”
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Un ensemble funéraire de l’Antiquité tardive à dépôt atypique d’âne à Woippy (Moselle) by Gaël Brkojewitsch, Olivier Putelat

“…An archaeozoological study and a palaeogenetic analysis made it possible to identify the equine remains as belonging to an adult male donkey, between 5 and 6 years of age at the time of death and of fairly good stature (1.45 m on average). Perhaps slaughtered during a prior ceremony, this animal was also accompanied by material goods and was perfectly integrated into the row organisation of the burial space. …”
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Association of Serum Ferritin Levels With Obstructive Sleep Apnea in Overweight/Obese US Populations: A Population-Based Study From the NHANES by Zhang Y, Zhou P, Xu C, Su H, Li R, Sun L, Yang Y

“…A non-linear U-shaped association was observed between ferritin levels and OSA risk (P-non-linear = 0.029), with an inflection point at ln-transformed ferritin of 4.58 (corresponding to a serum ferritin concentration of 97.51 ng/mL). In female OSA patients, elevated ferritin levels were associated with increased all-cause mortality risk (Q4 vs Q2: HR: 5.46, 95% CI: 1.18– 25.16, P = 0.029, P for trend = 0.032).Conclusion: Ferritin levels in overweight/obese individuals show a U-shaped relationship with OSA risk, and elevated levels correlate with increased all-cause mortality in female overweight/obese OSA patients. …”
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Global insights into the genome dynamics of Clostridioides difficile associated with antimicrobial resistance, virulence, and genomic adaptations among clonal lineages by Mohammad Sholeh, Mohammad Sholeh, Masoumeh Beig, Masoumeh Beig, Ebrahim Kouhsari, Mahdi Rohani, Mohammad Katouli, Farzad Badmasti

“…Rare resistance genes like blaCTX-M-2, cfxA3, and blaZ appeared in only 0.005% of genomes. …”
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Protein Level and Infantile Diarrhea in a Postweaning Piglet Model by Jing Gao, Jie Yin, Kang Xu, Hui Han, ZeMin Liu, ChenYu Wang, TieJun Li, YuLong Yin

“…Also, the feed intake and body weights were reduced in the HP groups compared with the other group (P<0.05). The diarrhea-related mRNA abundances were analyzed by real-time PCR; the results showed that HP treatment markedly decreased the expression of aquaporin (AQP, P<0.05) and the tight junction protein (P<0.05), but increased inflammatory cytokines (P<0.01) than those in control group. …”
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Nutrient dynamics and discharge in a coastal sandy beach aquifer by Xuejing WANG, Yifan GUO, Shengchao YU, Qianqian WANG, Hailong LI, Chunmiao ZHENG

“…The estimated SGD rate was 1.49×106 m3/d, comparable to local river discharge. SGD-derived nutrients were estimated to be 983.0 kg/d for dissolved inorganic nitrogen (DIN), 37.00 kg/d for \begin{document}$ {\mathrm{P}\mathrm{O}}_{4}^{3-} $\end{document}, and 4023 kg/d for Si, making SGD a a significant source of nutrients to coastal waters. …”
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Insulin Resistance Associated with Plasma Xanthine Oxidoreductase Activity Independent of Visceral Adiposity and Adiponectin Level: MedCity21 Health Examination Registry by Masafumi Kurajoh, Shinya Fukumoto, Takayo Murase, Takashi Nakamura, Takuma Ishihara, Hirofumi Go, Kouji Yamamoto, Shinya Nakatani, Akihiro Tsuda, Tomoaki Morioka, Katsuhito Mori, Yasuo Imanishi, Masaaki Inaba, Masanori Emoto

“…The mean values for VFA, log HOMA-IR, and log plasma XOR activity were 76.8 ± 45.8 cm2, 0.14 ± 0.30, and 1.50 ± 0.44 pmol/h/mL, respectively. Multiple regression analysis showed that HOMA-IR was significantly (p=0.020) associated with plasma XOR activity independent of other factors, including VFA and adiponectin level, as well as age, sex, alcohol drinking habit, smoking habit, alanine transaminase, HbA1c, and eGFR. …”
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Active Moss Biomonitoring of Mercury in the Mine-Polluted Area of Abbadia San Salvatore (Mt. Amiata, Central Italy) by Federica Meloni, Sergio Calabrese, Orlando Vaselli, Francesco Capecchiacci, Francesco Ciani, Lorenzo Brusca, Sergio Bellomo, Walter D’Alessandro, Kyriaki Daskalopoulou, Stefania Venturi, Barbara Nisi, Daniele Rappuoli, Franco Tassi, Jacopo Cabassi

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Proof of concept for multirotor systems with vortex-generating modes for regenerative wind energy: a study based on numerical simulations and experimental data by F. Avila Correia Martins, A. van Zuijlen, A. van Zuijlen, C. Simão Ferreira

“…In configurations with two or four ABL-control wings, the total wind power in the wake recovers to 95 % of the free-stream value at positions as early as <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M1" display="inline" overflow="scroll" dspmath="mathml"><mrow><mi>x</mi><mo>/</mo><mi>D</mi><mo>≈</mo><mn mathvariant="normal">6</mn></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="42pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="f1f50c65a676d34319b7e018d39c81d7"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="wes-10-41-2025-ie00001.svg" width="42pt" height="14pt" src="wes-10-41-2025-ie00001.png"/></svg:svg></span></span> downstream of the multirotor system, representing a recovery rate that is approximately an order of magnitude faster than that observed in the baseline wake without ABL-control capabilities. …”
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Screening potential diagnostic biomarkers for PLA2R‑associated idiopathic membranous nephropathy by WGCNA analysis and LASSO algorithm by Jinxu Huang, Yaqing Huang, Xiaoling Zeng, Yuhong Zhang, Junneng Zhang, Qingchu Hong, Yongtiao Peng

“…The onset of phospholipase A2 receptor (PLA2R1)-associated IMN is critically linked to M-type PLA2R1 exposure, yet the mechanism underlying glomerular injury remains unclear. …”
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Perspectives of Women with Breast Cancer and Healthcare Providers Participating in an Adherence-Enhancing Program for Adjuvant Endocrine Therapy: A Qualitative Study by Véronique Turcotte, Laurence Guillaumie, Martine Lemay, Anne Dionne, Julie Lemieux, Angéline Labbé, Carolyn Gotay, Line Guénette, Sophie Lauzier

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The Genealogy of Šemetas' in 15th-16th century by Saulė Viskantaitė-Saviščevienė

“…Moreover, the monarch appreciated Merkelis as a person, and he was appointed to edit the Second Lithuanian Statute. In 1569, M. Šemeta, together with other famous representatives of the GDL elite—the Lithuanian liege lords—were participants in the Parliament (Sejm) of Lublin when the project of the union was discussed.   …”
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