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61901
The Influence of Overnight Orthokeratology on Ocular Surface and Meibomian Gland Dysfunction in Teenagers with Myopia
Published 2019-01-01“…The following tests were performed before and after 1, 3, 6, 12, and 24 months of OOK lens wear, including ocular surface disease index (OSDI) questionnaire, slit-lamp examination, and Keratograph 5M. Results. No infectious keratitis occurred during the study. …”
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61902
High tumor mutational burden predicts favorable response to anti-PD-(L)1 therapy in patients with solid tumor: a real-world pan-tumor analysis
Published 2023-04-01“…In contrast, exhausted T-cell and M2 macrophage counts were increased in the non-responder group.Conclusions The overall incidence of TMB status was analyzed by the TSO500 assay, and TMB-H was observed in 14.7% of the pan-cancer population. …”
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61903
Effect of glucagon-like peptide-1 receptor agonists on vascular risk factors among adults with type 2 diabetes and established atherosclerotic cardiovascular disease
Published 2025-03-01“…Results: In the final cohorts ([1] OW GLP-1 RA including semaglutide: n = 20,084; [2] OW GLP-1 RA excluding semaglutide: n = 16,894; [3] semaglutide: n = 3,435), significant mean reductions (P < 0.001) were observed from baseline to post-index in hemoglobin A1c (%, [1] -1.1; [2] -1.1; [3] -1.2), low-density lipoprotein cholesterol (mg/dL, [1] -6.4; [2] -6.4; [3] -6.9), total cholesterol (mg/dL, [1] -11.0; [2] -11.1; [3] -10.7), triglycerides (mg/dL, [1] -31.8; [2] -31.4; [3] -33.1), systolic blood pressure (mmHg, [1] -1.5; [2] -1.2; [3] -3.1), body weight (kg, [1] -2.7; [2] -2.4; [3] -4.3) and body mass index (kg/m2; [1] -0.9; [2] -0.8; [3] -1.4). Largest reductions were observed in the top tercile. …”
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61904
Subcytotoxic transepidermal delivery using low intensity cold atmospheric plasma
Published 2025-01-01“…Within the determined safety range, mechanistic analyses were conducted to examine LICAP-enhanced delivery pathways. mRNA expression and protein levels of tight and adherens junction genes were quantified, and changes in ultramicroscopic morphology of HaCaT monolayers were investigated. …”
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61905
Endogenous sex hormone levels are associated with the revised Framingham Stroke Risk Profile in postmenopausal women: a longitudinal study in a Swedish cohort
Published 2025-01-01“…Women who were ≥55 years old, with estradiol levels below 20 pg/mL, not using hormonal therapy, and with no self-reported history of stroke, were included (N = 133). …”
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61906
Enhanced expression of ten‐eleven translocation 1 reverses gemcitabine resistance in cholangiocarcinoma accompanied by a reduction in P‐glycoprotein expression
Published 2019-03-01“…The expression of TET1 and P‐gp was evaluated in gemcitabine‐resistant CCA cells and their parental cells at mRNA and protein level by quantitative RT‐PCR and western blot analysis. …”
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61907
Reduction of the oxidative damage to H2O2-induced HepG2 cells via the Nrf2 signalling pathway by plant flavonoids Quercetin and Hyperoside
Published 2024-07-01“…In addition, quercetin was more efficient than hyperoside in enhancing the expression of Nrf2-associated mRNAs, increasing the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT), and reducing the cellular malondialdehyde (MDA) content. …”
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61908
Comparative Evaluation of Intra-articular Ozone and Steroid Treatments in Patients with Coxarthrosis under Ultrasound Guidance: A Retrospective Study
Published 2025-02-01“…Patients unresponsive to conventional treatments were divided into two groups: Group A (n=30) received intra-articular steroid (triamcinolone acetonide), and Group B (n=23) received three weekly ozone sessions (200 μg/20 mL), both under USG. Clinical outcomes were assessed using the Visual Analog Scale (VAS) for pain and the Harris Hip Score (HHS) for functional status, both pre- and post-treatment. …”
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61909
椎旁注射臭氧对SD大鼠盘源性疼痛模型的镇痛作用
Published 2019-01-01“…模型组和臭氧组大鼠经皮穿刺L5-6椎间盘全层纤维环制作SD大鼠盘源性疼痛模型,臭氧组在造模后第22天椎旁注射25mg/L臭氧1mL,对照组大鼠不作处理。手术前后各时间点使用定量痛觉敏感评估技术和磁共振检查实验动物的50%机械撤足阈值(50%MWT)和椎间盘Pfirrmann分级,并使用western blot检测左侧坐骨神经和背根神经节中肿瘤坏死因子α(TNF-α)和降钙素基因相关肽(CGRP)的表达。…”
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61910
Forest land-use change affects soil organic carbon in tropical dry forests of the Peruvian Amazon
Published 2025-01-01“…Material and methods: A total of 24 plots of 100 m2 were selected in primary (~200 years), intervened (~50 years since intervention), and deforested forests (10 years ago), with 120 soil samples collected across five depths. …”
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61911
Analysis of influencing factors of washed microbiota transplantation in treating patients with metabolic syndrome
Published 2025-02-01“…Not only the changes in body mass index [BMI = weight (kg)/height (m)2], blood glucose, blood lipids, and blood pressure were analyzed, but also the influencing factors of WMT in treating MS patients were carried out based on Logistic Regression. …”
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61912
Notation publications in the context of musical life in Lithuania in the XVI-XVII centuries
Published 2024-08-01“…The greater part of books published in Vilnius in 1598 (M. Petkevičius' Katekizmas) and in Kėdainiai (Knygos nobažnystės krikščioniškos in 1653) were hymnals whose hymns were based on melodies from the above-mentioned Vilnius publications. …”
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61913
Odor-active aroma compounds in traditional fermented dairy products: The case of mabisi in supporting food and nutrition security in Zambia
Published 2025-01-01“…The PTR-QiTOF-MS run identified and quantified a total of 390 m/z peaks, 55 of which were tentatively identified. 16S rRNA amplicon sequencing revealed a diverse microbial community, with Lactococcus species dominating. …”
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61914
High-resolution mapping of global winter-triticeae crops using a sample-free identification method
Published 2025-01-01“…We considered state (or province) or country to be an identification unit and employed the WTCI to produce the first global 30 m resolution distribution maps of winter-triticeae crops from 2017 to 2022 using Landsat and Sentinel images. …”
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61915
Neutrophil Gelatinase-Associated Lipocalin in Kidney Transplantation Is an Early Marker of Graft Dysfunction and Is Associated with One-Year Renal Function
Published 2013-01-01“…Shortly after KTx (3–6 h), uNGAL values were higher in DGF recipients (on average +242 ng/mL, considering mean dialysis time of 4.1 years) and rose further in following days, contrasting with prompt function recipients. …”
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61916
Predicting survival rates: the power of prognostic nomograms in distal cholangiocarcinoma
Published 2025-01-01“…Decision curve analysis was used to evaluate the model and its clinical applicability.ResultsThe findings demonstrated that Grade, M stages, Surgery, and Chemotherapy emerged as autonomous prognostic factors for the survival of individuals with dCCA. …”
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61917
Magnesium ions regulate the Warburg effect to promote the differentiation of enteric neural crest cells into neurons
Published 2025-01-01“…The binding affinity of magnesium ions with the glycolytic key enzyme 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 was found to be 1.08 μM. Inhibiting glycolysis suppressed ENCCs differentiation into neurons, emphasizing its crucial role. …”
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61918
Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties
Published 2025-01-01“…These substances were then subjected to molecular docking studies via Auto dock Vina software to determine their affinity for binding to proteins from different bacterial strains including (Staphylococcus epidermidis (S. epidermidis), Staphylococcus aureus (S. aureus), Mycobacterium luteus (M. luteus), Salmonella typhi (S.typhi), Bacillus subtilis (B. subtilis), and Escherichia coli (E. coli) and fungal (Candida glabrata (C. glabrata), Candida albicans (C. albicans), and Saccharomyces cerevisiae (S. cerevisiae) strains. …”
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61919
Successful Endoscopic Injection Sclerotherapy of High-Risk Gastroesophageal Varices in a Cirrhotic Patient with Hemophilia A
Published 2010-01-01“…Esophageal endoscopic injection sclerotherapy (EIS) was performed with a total 15 mL of 5% ethanolamine oleate with iopamidol (EOI). …”
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61920
Muscle power is associated with higher levels of walking capacity and self-reported gait performance and physical activity in individuals with cerebral palsy
Published 2025-01-01“…Walking capacity was measured using the 10-m walk test fast (FS) and self-selected (SS) speeds and the 1-min walk test (1MWT). …”
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