Molecular characterization, chemical profile and biological properties of essential oils from Chamaemelum nobile (L.) flowers of Morocco: in vitro and in silico studies by El-Mehdi El-Assri, El-Mehdi El-Assri, Youssef El-Assri, Rajae El Brahimi, Mohamed El fadili, Asmae Baghouz, Hatem A. Abuelizz, Sara Er-Rahmani, Amal Lahkimi, Abdelhak Bouia

“…CN-EO exhibited strong antioxidant activity (IC50 = 135.8 ± 1.03 μg/mL). Antimicrobial assays revealed inhibition zones of up to 20.67 ± 0.58 mm (Staphylococcus aureus) and antifungal inhibition of 40.42% ± 2.82% against Aspergillus flavus. …”
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Optimisation of controlled reproduction protocol in broadhead catfish (Clarias macrocephalus Günther, 1864) using Ovopel™: Effect of different hormonal treatment methods on reprodu... by Nguyễn Ngọc Quyến, Nguyễn Thanh Tâm, Thạch Anh Pha, Lý Anh Thuật, Nguyễn Ngọc Lợi, Nguyễn Thị Trúc Quyên, László Horváth, Tamás Müller

“…This study aims to establish novel protocols for hormonal delivery methods and dosages of Ovopel™ (D-Ala6, Pro9 NEt-mGnRH plus metoclopramide) for spawning induction of female broadhead catfish (Clarias macrocephalus) in control conditions. …”
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Clinical Performance of MAGLUMI Diagnostic Tests for the Automated Detection of Dengue Virus by Bo Peng, Zhonggang Fang, Cong Li, Kun Liu, Ting Wang, Ke Huang, Fan Yang, Yalan Huang, Chunli Wu, Yue Li, Dana Huang, Qian Zhang, Yijun Tang, Xiaolian Liu, Wei Rao, Xiaolu Shi

“…Additionally, the consistency of NS1, IgM, and IgG tests on the MAGLUMI platform compared to commercial comparator reagents reaches 85.71%, 99.25%, and 98.97%, respectively. …”
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Alleviating heat stress on broiler breeder hens: Effect of dietary antioxidant supplementation on reproductive performance, egg quality, offspring growth, and antioxidant capacity by Phocharapon Pasri, Chayanan Pukkung, Pascal Mermillod, Nadine Gérard, Orapin Jantasaeng, Merisa Sirisopapong, Supattra Okrathok, Thanatat Thiabching, Sitthipong Rakngam, Kanokwan Kamkajon, Yongcai Zhu, Sutisa Khempaka

“…Either antioxidant source can improve free radical scavenging, reduce lipid peroxidation, upregulate the relative expression of SOD, CAT, and GSH-Px mRNA, and downregulate HSP90 in offspring liver (P < 0.05). …”
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Real-world clinical evidence of oral semaglutide on metabolic abnormalities in subjects with type 2 diabetes: a multicenter retrospective observational study (the Sapporo-Oral SEMA... by Sho Furusawa, Hiroshi Nomoto, Chiho Oba-Yamamoto, Jun Takeuchi, Miki Ito, Hiroyoshi Kurihara, Shin Aoki, Aika Miya, Hiraku Kameda, Akinobu Nakamura, Tatsuya Atsumi

“…Of 543 subjects who met the inclusion criteria, data for 434 subjects (age 55.5 ± 12.6 years; body mass index 29.6 ± 6.0 kg/m2) were analyzed. After a 6 months of observation period, semaglutide 3 mg, 7 mg, or 14 mg was used by 55 (12.7%), 241 (55.5%), and 138 (31.8%) of subjects, respectively. …”
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¹³¹I标记的肝癌核酸纳米火车的制备及生物分布研究 by 林雪, 许杰华, 段亚妮, 朱雁秋, 储圆圆, 刘明明, 覃杰

“…尾静脉注射¹³¹Ⅰ-NT后，荷瘤小鼠体内 30 min、1 h、2 h肿瘤部位每克组织放射性摄取值分别为（4.90±0.55）%ID/g、（10.12±0.32）%ID/g、（4.25±0.31）%ID/g，T/M比值相应为7.33±2.04、36.54±12.72、44.93±7.90。结论成功构建了¹³¹I标记的长链核酸纳米火车，具有较好体外稳定性，对HepG2细胞及HepG2细胞荷瘤小鼠模型具有较高的靶向性，显示¹³¹Ⅰ-NT可能是一种具有潜力的靶向人肝癌的核素载体，为肝癌靶向核素诊疗提供新思路。…”
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RETRACTED: Long non‐coding RNA Sox2OT promotes coronary microembolization‐induced myocardial injury by mediating pyroptosis by Liying Xuan, Danni Fu, Dong Zhen, Dongsong Bai, Lijun Yu, Guohua Gong

“…Silencing of Sox2OT favoured miR‐23b binding to 3′UTR of TLR4 mRNA leading to suppressed TLR4‐mediated NFKB signalling and pyroptosis in myocardial tissues harvested from CME rat models. …”
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Optimizing Automated Hematoma Expansion Classification from Baseline and Follow-Up Head Computed Tomography by Anh T. Tran, Dmitriy Desser, Tal Zeevi, Gaby Abou Karam, Julia Zietz, Andrea Dell’Orco, Min-Chiun Chen, Ajay Malhotra, Adnan I. Qureshi, Santosh B. Murthy, Shahram Majidi, Guido J. Falcone, Kevin N. Sheth, Jawed Nawabi, Seyedmehdi Payabvash

“…We utilized three separate multicentric cohorts for cross-validation/training, internal testing, and external validation (<i>n</i> = 2261) to develop and test a pipeline for automated hematoma segmentation and to generate ground truth binary HE annotations (≥3, ≥6, ≥9, and ≥12.5 mL). Applying a 95% sensitivity threshold for HE classification showed a practical and efficient strategy for HE annotation in large ICH datasets. …”
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How do leaf functional traits influence above-ground tree carbon in tropical hill forests of Bangladesh? by Ariful Khan, Md Rezaul Karim, Mohammed A.S. Arfin-Khan, Md. Shamim Reza Saimun, Fahmida Sultana, Sharif A. Mukul

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Positive end-expiratory pressure and risk of postoperative pulmonary complications in patients living at high altitudes and undergoing surgery at low altitudes: a single-centre, re... by Zhuoning Li, Kaixi Shang, Zongjing Xia, Xiaoli Ye, Chongcong Gong

“…Objectives To examine whether a high positive end-expiratory pressure (PEEP ≥5 cmH2O) has a protective effect on the risk of postoperative pulmonary complications (PPCs) in a cohort of patients living at high altitudes and undergoing general anaesthesia.Design Retrospective, observational study.Setting A tertiary hospital in China.Participants Adult Tibetan patients living at high altitudes (≥3000 m) and who went to the low-altitude plain to undergo non-cardiothoracic surgery under general anaesthesia, from January 2018 to April 2020.Measurements This study included 1905 patients who were divided according to the application of an intraoperative PEEP: low PEEP (&lt;5 cmH2O, including 0 cmH2O) or high PEEP (≥5 cmH2O). …”
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Hepatokine leukocyte cell‐derived chemotaxin 2 as a biomarker of insulin resistance, liver enzymes, and metabolic dysfunction‐associated steatotic liver disease in the general popu... by Keita Suzuki, Hiromasa Tsujiguchi, Akinori Hara, Yumie Takeshita, Hisanori Goto, Yujiro Nakano, Reina Yamamoto, Hiroaki Takayama, Atsushi Tajima, Tatsuya Yamashita, Masao Honda, Hiroyuki Nakamura, Toshinari Takamura

“…Results The mean age and body mass index (BMI) of participants were 63.5 ± 10.2 years and 23.0 ± 3.1 kg/m2, respectively. Higher LECT2 levels positively correlated with homeostatic model assessment for insulin resistance (HOMA‐IR) values and negatively correlated with the quantitative insulin sensitivity check index (QUICKI) among all participants (HOMA‐IR; non‐standardized β (B) = 6.38, P < 0.01: QUICKI; B = −161, P < 0.01). …”
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N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1 by Toru Miwa, Toru Miwa, Akihito Tarui, Akihito Tarui, Teppei Kouga, Yasunori Asai, Yasunori Asai, Hideaki Ogita, Hideaki Ogita, Taro Fujikawa, Nobuhiro Hakuba, Nobuhiro Hakuba

“…MNAM increased SIRT1 protein levels in the cochlea without altering Sirt1 mRNA, suggesting post-transcriptional regulation. …”
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Cardio-renal effect of dapagliflozin and dapagliflozin- saxagliptin combination on CD34 + ve hematopoietic stem cells (HSCs) and podocyte specific markers in type 2 diabetes (T2DM)... by Seshagiri Rao Nandula, Arad Jain, Sabyasachi Sen

“…CD34 + HSC number, migration, mRNA expression along with biochemistry and urine exosomes were measured. …”
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Distinct Impacts of Clinicopathological and Mutational Profiles on Long-Term Survival and Recurrence in Medullary Thyroid Carcinoma by Moon Young Oh, Kyong Yeun Jung, Hoonsung Choi, Young Jun Chai, Sun Wook Cho, Su-jin Kim, Kyu Eun Lee, Eun-Jae Chung, Do Joon Park, Young Joo Park, Han-Kwang Yang

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The potential benefits of radiotherapy in elderly patients with early-stage triple-negative breast cancer by Zheng Xu, Zheng Xu, Chengdong Qin, Binxiao Cao, Binxiao Cao, Pengcheng Ruan, Pengcheng Ruan, Mianhao Zhang, Mianhao Zhang, Guidong Chen, Guidong Chen

“…This study will analyze the role of radiotherapy (RT) in early-stage triple-negative breast cancer (TNBC) among elderly patients using the SEER database to assess its impact on survival outcomes.MethodsThe patients aged 70+ with T1-2N0-1M0 TNBC were selected from the SEER database (2010–2015) according to specific inclusion and exclusion criteria. …”
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Non Linear Thermal Radiation Analysis of Electromagnetic Chemically Reacting Ternary Nanofluid Flow over a Bilinear Stretching Surface by Shobha V, Hasan Mulki, Baskar P, S. Suresh Kumar Raju, Saleh Mahmoud, Mostafa Abdrabboh, S.V.K. Varma

“…Aim and Objective: The research seeks to analyze heat,velocity and concentration transfer rates in a three-dimensional flow system with two thermo physical models.The study focuses on the effects of magnetic field strength (M), stretching ratio (λ), Radiation parameter (R) and rotational parameter (γ) on heat transfer and fluid flow. …”
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Assessment of Water Surface Reflectance and Optical Water Types Over Two Decades in Europe&#x0027;s Largest Artificial Lake: An Intercomparison of ESA and NASA Satellite Data by Goncalo Rodrigues, Miguel Potes, Maria Joao Costa

“…However, when using MODIS, which covers only the central area of the reservoir, only three clusters were identified as the ideal number. Using 300 or 1000 m of spatial resolution, the Alqueva reservoir mostly exhibits high water transparency, associated with low surface reflectances for the majority of the time. …”
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Association and multimodal model of retinal and blood-based biomarkers for detection of preclinical Alzheimer’s disease by Swetha Ravichandran, Peter J. Snyder, Jessica Alber, Charles F. Murchison, Lauren E. Chaby, Andreas Jeromin, Edmund Arthur

“…The Spectralis II system (Heidelberg Engineering) was used to acquire macular centered Spectral Domain Optical Coherence Tomography (SD-OCT) images for evaluation of putative retinal gliosis surface area and macular retinal nerve fiber layer (mRNFL) thickness. For all participants, correlations (adjusted for age and correlation between eyes) were assessed between retinal and blood-based biomarkers. …”
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Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation by Yong Yi, Guoqiang Wang, Wenhua Zhang, Shuhan Yu, Junjie Fei, Tingting An, Jianqiao Yi, Fengtian Li, Ting Huang, Jian Yang, Mengmeng Niu, Yang Wang, Chuan Xu, Zhi-Xiong Jim Xiao

“…Mechanistically, glucose deprivation activates Ras signaling to enhance MT-CO2 transcription and inhibits IGF2BP3, an RNA-binding protein, to stabilize MT-CO2 mRNA. Elevated MT-CO2 increases flavin adenosine dinucleotide (FAD) levels in activating lysine-specific demethylase 1 (LSD1) to epigenetically upregulate JUN transcription, consequently promoting glutaminase-1 (GLS1) and glutaminolysis for tumor cell survival. …”
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Energy Transfer of Electronic Excitations by Activators in Phosphates and Sulfates via the Creation of Combined Electron Emission States by Aibek S. Nurpeissov, Temirulan T. Alibay, Turlybek Nurakhmetov, Aivaras Kareiva, Aleksej Zarkov, Sapargali Pazylbek

“…Radiative states are excited by photon energies of ~4.5 eV and ~4.0 eV, resulting in recombination emissions at 3.06–3.1 eV and 2.92–2.95 eV, as well as activator emissions at 2.06 eV for <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mrow><mi>M</mi><mi>n</mi></mrow><mrow><mn>2</mn><mo>+</mo></mrow></msup></mrow></semantics></math></inline-formula>, 2.5 eV for <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mrow><mi>T</mi><mi>b</mi></mrow><mrow><mn>3</mn><mo>+</mo></mrow></msup></mrow></semantics></math></inline-formula>, and 2.56 eV and 2.16 eV for <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mrow><mi>D</mi><mi>y</mi></mrow><mrow><mn>3</mn><mo>+</mo></mrow></msup></mrow></semantics></math></inline-formula>. …”
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