Anti-inflammatory and antioxidant properties of Camellia sinensis L. extract as a potential therapeutic for atopic dermatitis through NF-κB pathway inhibition by Min Jung Kim, Ye Jin Yang, Ga-Yul Min, Ji Woong Heo, Jae Dong Son, Young Zoo You, Hun Hwan Kim, Gon Sup Kim, Hu-Jang Lee, Ju-Hye Yang, Kwang Il Park

“…Exposure of TNF-α/IFN-γ- stimulated human keratinocytes (HaCaT) cells to CSE resulted in a 200 µg/mL dependent inhibition of p65 and signal transducer and activator of transcription 1 (STAT-1) translocation from the cytosol to the nucleus, as confirmed through immunofluorescence (IF) staining. …”
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Multi-targeted nanogel drug delivery system alleviates neuroinflammation and promotes spinal cord injury repair by Penghui Wang, Zaifeng Chen, Ping Li, Abdullah Al Mamun, Shaoxia Ning, Jinjing Zhang, Chonghui Tang, Tianmiao Sun, Jian Xiao, Xiaojie Wei, Fenzan Wu

“…Crucially, our findings reveal that QLipTC@HDM induces M2 phenotype transformation in glial cells and in mice with SCI, thereby mitigating inflammation. …”
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Case report: Successful treatment of hyperbaric oxygen for radiation-induced hemorrhagic cystitis in a 95-year-old patient with bladder cancer by Li Lin, Li Lin, Man He, Yanyan Zeng, Xiaoxiao Ni, Yequn Guo, Xiaojuan Xie, Lingling Sun, Huai Huang

“…However, there is a lack of reported data addressing the applicability of HBOT in very elderly patients (over 90 years old) with severe bleeding necessitating multiple blood transfusions.Case presentationThe patient is a 95-year-old male who suffered from severe hematuria due to RHC after 33 sessions of radiotherapy for muscle-invasive bladder cancer (T2N0M0, stage: II). After a series of subsequent therapies that failed to control the hematuria, the patient received 196 HBOTs between 11 October 2022 and 23 October 2023. …”
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Smaller-incision new-generation implantable miniature telescope in late-stage age-related macular degeneration: 6 month outcomes by Mario Damiano Toro, Alfonso Savastano, Faustino Vidal Aroca, Paola Sasso, Giuseppe Francione, Gaetano Fioretto, Marina Montemagni, Claudio Xompero, Nicola Claudio D'Onofrio, Ciro Costagliola, Stanislao Rizzo

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Improving H2RG Performance in SPHEREx Brassboard Model by Chi H. Nguyen, Phillip Korngut, C. Darren Dowell, James Bock, Jill Burnham, Samuel Condon, Walter Cook, Grigory Heaton, Howard Hui, Branislav Kecman, Hiromasa Miyasaka, Kenneth Manatt, Hien T. Nguyen, Stephen Padin, Marco Viero

“…Spectro-Photometer for the History of the Universe, Epoch of Reionization, and Ices Explorer is an upcoming NASA satellite mission to study the physics of inflation, the history of galaxy formation, and the abundance of biogenic ices in the Milky Way, obtaining the first all-sky spectroscopic survey at infrared wavelengths 0.75–5.0 μ m. The instrument implements HAWAII-2RG (H2RG) detectors and custom-built Video8 electronics with multiple sampling features to optimize the H2RG noise performance, including nonsequential row reads, voltage monitoring, multiple visits to optically dark reference pixels, as well as onboard slope fitting and cosmic-ray removal. …”
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Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers by Leandro da Silva Borges, José Ricardo Bortolon, Vinicius Coneglian Santos, Nivaldo Ribeiro de Moura, Alexandre Dermargos, Maria Fernanda Cury-Boaventura, Renata Gorjão, Tania Cristina Pithon-Curi, Elaine Hatanaka

“…Herein, we investigated the effects of a ballet class on the kinetic profiles of creatine kinase (CK) and lactate dehydrogenase (LDH) activities, cytokines, complement component 3 (C3), and the concentrations of immunoglobulin (Ig), IgA and IgM, in ballerinas. We also verified neutrophil death and ROS release. …”
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Free fatty acids may regulate the expression of 11β-hydroxysteroid dehydrogenase type 1 in the liver of high-fat diet golden hamsters through the ERS-CHOP-C/EBPα signaling pathway... by Dandan Liu, Peipei Tian, Yilin Hou, Tingxue Zhang, Xiaoyu Hou, Lifang Liu, Xiaolong Li, Kunjie Zheng, Chao Wang, Guangyao Song

“…Western blot and RT-PCR results indicated higher GRP78, CHOP, C/EBPα, and 11β-HSD1 protein and mRNA expression in the HF group compared to the Con group (Ps < 0.05). …”
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EFECTO DEL TIPO DE PROPULSION EN LA FRECUENCIA CARDIACA MAXIMA Y EN LA PERCEPCION DEL ESFUERZO EN CARRERA by Pietro Scaglioni Solano, Luis Fernando Aragón Vargas

“…Este estudio examina el efecto del tipo de propulsión sobre la Frecuencia Cardíaca (FC) y el Esfuerzo Percibido (EP, Escala de Borg) en el ejercicio de carrera, obtenidas durante dos protocolos equivalentes, en terreno plano (pendiente 0%), uno con propulsión externa (motor, en la banda sinfín) y otro con autopropulsión (carrera en pista de atletismo). 14 corredores (34.3 +/- 9.77 años, 1.74 +/- 0.06m, 75.3 +/- 10.3 Kg) realizaron un protocolo que consistía en un calentamiento de 30 min. a una intensidad entre 60 y 70% de FCmáx. seguido de un incremento gradual de la intensidad del ejercicio, aumentando la velocidad de calentamiento 1.6 Km/h cada 30 seg., llevando al sujeto a un esfuerzo máximo en un lapso de 3 a 4 minutos, se recupera hasta la condición de calentamiento, se repite dos veces el proceso de incremento gradual y recuperación, escogiendo el valor máximo de FC y EP de los tres obtenidos. …”
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Overcoming barriers to the development of clean and digital energy start-ups: access to credit and protection of minority investors' rights by Artyukhov Artem, Oleksii Havrylenko, Olena Churikanova, Kseniia Mohylna

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United by Sports? Key Factors affecting Sports Participation in a Sports-based Initiative to Promote Social Integration in Segregated Communities by Anna Boemmel, Matthias Buser, Thomas Persson

“…Routledge. https://doi.org/10.4324/9781315266084 Dahlstedt, M., & Ekholm, D. (2018). Social exclusion and multiethnic suburbs in Sweden. …”
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The hydraulic performance and clogging characteristics of a subsurface drip irrigation system operating for five years in the North China plain by Li Zaiyu, Mo Yan, Gao Hao, Gong Shihong, Zhang Yanqun, Li Guangyong, Wu Feng

“…The proportions of clogging substances in the emitter flow channels (mc), outlet (mo), and intrusion root (mr) dry weight were 28.9 %, 69.3 %, and 1.8 % of the total clogging substance dry weight (M), respectively. The particle size distributions of the clogging substances at the outlets were similar to those of the surrounding soil, which was caused mainly by negative pressure suction. …”
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Survival in patients with CKD 3–5 after 12 months of exercise training – a post-hoc analysis of the RENEXC trial by Sara Denguir, Matthias Hellberg, Martin Almquist, Naomi Clyne

“…Results 151 patients participated, mean age 66 ± 14 years, 65% men, eGFR 22.5 ± 8.2 ml/min/1.73m2, average follow-up 60 months. Multivariate analyses The baseline 6-minute walk test (6MWT) (HR 0.996; 95% CI [0.993–0.998]) and 30-second sit-to-stand (30s-STS) (HR 0.94 CI [0.89–1.0]) were positively associated with survival. …”
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Identification of Potential Diagnostic Biomarkers of Carotid Atherosclerosis in Obese Populations by Wu X, Pan J, Pan X, Kang J, Ren J, Huang Y, Gong L, Li Y

“…In vivo experiments showed that MMP9, PLA2G7, CD52, SPP1, FYB, and PLCB2 mRNA levels were up-regulated in adipose, aortic tissues and serum of OB and AS model mice, CLEC5A was up-regulated in aorta and serum, and PRKCB was up-regulated in adipose and serum.Conclusion: MMP9, PLA2G7, CD52, CLEC5A, SPP1, and FYB may serve as potential diagnostic biomarkers for CAS in obese populations. …”
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A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma by Yonglin Luo, Wenyang Wei, Yaxuan Huang, Jun Li, Weiling Qin, Quanxiang Hao, Jiemei Ye, Zhe Zhang, Yushan Liang, Xue Xiao, Yonglin Cai

“…Moreover, the expression of RBL2, E2F1, and CDC25C were significantly correlated with the expression of caspase family genes. Finally, the lower mRNA and protein expression of RBL2 were validated in NPC cell lines and tissues. …”
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Status of seawater intrusion in Mexico: A review by Xiaoxiao Zha, Jesús Horacio Hernández Anguiano, Francisco Padilla Benítez, Arturo Cruz-Falcón, Raul Miranda-Avilés, Manuel E. Mendoza Cantú, Jorge Adrian Perera-Burgos, Xu Liao, Juan Manuel Navarro-Céspedes, Miguel Angel Acosta-Reyes, Yanmei Li

“…Groundwater analysis reveals diverse intrusion patterns, with below-sea-level water tables extending up to 60 km inland and depths reaching −100 m in Sonora, while the Yucatán Peninsula maintains water tables above sea level. …”
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Simulation of the heat mitigation potential of unsealing measures in cities by parameterizing grass grid pavers for urban microclimate modelling with ENVI-met (V5) by N. Eingrüber, A. Domm, W. Korres, K. Schneider

“…We found a maximum cooling potential of up to <span class="inline-formula">−20.1</span> K for ground surface temperature and up to <span class="inline-formula">−7.1</span> K for air temperature at 1 m above ground level for the hottest hour of a simulated 3 d heat wave in summer 2022, which represents a 20-year heat event in Cologne. …”
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A 1-Year Sediment Trap Study on the Downward Flux of Polycyclic Aromatic Hydrocarbons by Settling Particulate Matter in Deep Basins of the Aegean and Ionian Seas, Northeastern Medi... by Ester Skylaki, Constantine Parinos, Maria Tsagkaraki, Ioannis Hatzianestis, Anastasia Christidi, Elisavet Skampa, Ioanna Nikolopoulou, Georgia Kambouri, Ioanna Stavrakaki, Dimitris Velaoras, Giorgos Kouvarakis, Maria V. Triantaphyllou, Maria Kanakidou, Nikolaos Mihalopoulos, Alexandra Gogou

“…Atmospheric deposition seems to be the main transport pathway of pyrolytic PAHs in this site, while its high-water column depth (4300 m) compared to the other sites presumably enables extended degradation of organic constituents during particle settling. …”
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Lactiplantibacillus plantarum (CECT7484 and CECT7485) and Pedioccoccus acidilactici (CECT7483) enhance actin cytoskeleton and CYP1A1 expression restoring epithelial permeability al... by Maria Raffaella Barbaro, Francesca Bianco, Cesare Cremon, Giovanni Marasco, Francesca Bonomini, Marta Palombo, Cecilia Delprete, Marta Perez, Jordi Espadaler-Mazo, Vincenzo Stanghellini, Simone Guglielmetti, Giovanni Barbara

“…Twenty-one IBS patients diagnosed according to ROME IV criteria (11 IBS-D and 10 IBS-M) and 7 healthy controls were enrolled. Mucosal mediators spontaneously released by IBS and HC biopsies were collected and incubated with/without the PB (104 and 106 CFU/ml). …”
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Alpha and Theta Oscillations Associated With Behavioral Phenotypes of Pain–Attention Interaction by Nikou Kelardashti, Benjamin T. Dunkley, Rima El‐Sayed, Vaidhehi Veena Sanmugananthan, Junseok Andrew Kim, Natalie Rae Osborne, Joshua C. Cheng, Anton Rogachov, Rachael L. Bosma, Ariana E. Besik, Karen Deborah Davis

“…Method Fifty participants (27 F, 23 M) underwent resting‐state magnetoencephalography (MEG). …”
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Early Weaning Impairs the Growth Performance of Hu Lambs Through Damaging Intestinal Morphology and Disrupting Serum Metabolite Homeostasis by Haoyun Jiang, Haibo Wang, Haobin Jia, Yuhang Liu, Yue Pan, Xiaojun Zhong, Junhong Huo, Jinshun Zhan

“…As for the serum parameters, the concentrations of glucose on D33, D36, and D45 (<i>p</i> < 0.001), and the IL-6 content on D45 (<i>p</i> = 0.018) were observed to be lower, while the levels of immunoglobulin A (IgA) (<i>p</i> = 0.027), IgG (<i>p</i> = 0.035), and IgM (<i>p</i> = 0.002) on the four ages were all higher in the EW group than those in CON group. …”
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