Insights into a Renowned Fishery: Distinct Spatial Patterns, Environmental Predictors and Species Associations of Trophy-Class Spotted Seatrout (<i>Cynoscion nebulosus</i> [Cuvier... by Catherine Eckert, Elliot Briell, Ethan Getz

“…Depth, turbidity, and season were good predictors of the abundance of adult-class trout, which were most abundant at increased depths (>2 m), low-to-moderate turbidity (~125 NTU), and in the spring season (April–June). …”
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CDC20‐Mediated Selective Autophagy Degradation of PBRM1 Affects Immunotherapy for Renal Cell Carcinoma by Yizeng Fan, Weichao Dan, Taotao Que, Yi Wei, Bo Liu, Zixi Wang, Yulin Zhang, Yuzhao Wang, Tianjie Liu, Yanxin Zhuang, Mengxing Li, Chendong Guo, Jin Zeng, Bohan Ma, Lei Li

“…Here, it is demonstrated that PBRM1 knockdown induced M1 macrophage polarization and infiltration, which enhanced the efficacy of anti‐PD‐1 immunotherapy in RCC. …”
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Impact of Postshock Transcutaneous Pacing on Chest Compression Quality during Resuscitation: A Simulation-Based Pilot Study by Wojciech Telec, Tomasz Kłosiewicz, Radosław Zalewski, Julia Żukowska-Karolak, Artur Baszko, Mateusz Puślecki

“…In the second, simultaneous with compressions, one of the rescuers started transcutaneous pacing (TCP) with a current output of 200 mA and a pacer rate of 80 ppm. TCP was finished after 30 seconds (experimental group). …”
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Cuproptosis-Related Signature Predicts the Prognosis, Tumor Microenvironment, and Drug Sensitivity of Hepatocellular Carcinoma by Xiangjun Qi, Jiayun Guo, Guoming Chen, Caishan Fang, Leihao Hu, Jing Li, Chi Zhang

“…However, the role of CRGs in Hepatocellular Carcinoma (HCC) remains unknown. Method. The mRNA transcriptome profiling data, somatic mutation data, and copy number gene level data of The Cancer Genome Atlas-Liver Hepatocellular Carcinoma project (TCGA-LIHC) were downloaded for subsequent analysis. …”
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Evaluation of longan (Dimocarpus longan) peel powder as fruit by-product additive in Nile tilapia (Oreochromis niloticus) feed: Effects on growth, immunity, and immune-antioxidant... by Supreya Wannavijit, Piyatida Outama, Chinh Le Xuan, Camilla Maria Fontana, Marina Paolucci, Md Afsar Ahmed Sumon, Ehab El-Haroun, Hien Van Doan

“…Similarly, analysis of mRNA transcripts of immune (IL-1, IL-8, and LBP) and antioxidant (GSTa, GPX, and GSR) gene expressions showed a significant upregulation (P < 0.05) in LP-fed diet groups compared to the control group. …”
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Jiawei Suanzaoren decoction for the treatment of perimenopausal insomnia: clinical observation and experimental study by Li-Qiong Chen, Yong-Can Zhou, Fang Ning, Ming-Jin Zhu

“…The mechanism behind this improvement may be related to the regulation of Estradiol (E2), Follicle-Stimulating Hormone (FSH), and luteinizing hormone (LH) levels, as well as the mRNA expression levels of 5-HT1a, 5-HT2a, GABAARα1, and GABAARγ2 receptors in the hypothalamus.…”
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Acute Exposure to Microcystin-Producing Cyanobacterium Microcystis aeruginosa Alters Adult Zebrafish (Danio rerio) Swimming Performance Parameters by Luiza Wilges Kist, Angelo Luis Piato, João Gabriel Santos da Rosa, Gessi Koakoski, Leonardo José Gil Barcellos, João Sarkis Yunes, Carla Denise Bonan, Maurício Reis Bogo

“…In this study, we assessed behavioral patterns and whole-body cortisol levels of adult zebrafish (Danio rerio) exposed to cell culture of the microcystin-producing cyanobacterium M. aeruginosa (MC-LR, strain RST9501). MC-LR exposure (100 μg/L) decreased by 63% the distance traveled and increased threefold the immobility time when compared to the control group. …”
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Antifungal Activity of Genistein Against Phytopathogenic Fungi <i>Valsa mali</i> Through ROS-Mediated Lipid Peroxidation by Fangjie Li, Chen Yang, Maoye Li, Su Liu, Kuo Xu, Xianjun Fu

“…Our serendipitous findings revealed that genistein significantly inhibits the mycelial growth of <i>V. mali</i>, with an inhibition rate reaching 42.36 ± 3.22% at a concentration of 10 µg/mL. Scanning electron microscopy analysis revealed that genistein caused significant changes in the structure of <i>V. mali</i>, including mycelial contraction, distortion, deformity, collapse, and irregular protrusions. …”
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Seroprevalence of Foot and Mouth Disease Virus Infection in Some Wildlife and Cattle in Bauchi State, Nigeria by Y. J. Atuman, C. A. Kudi, P. A. Abdu, O. O. Okubanjo, A. Abubakar, Y. Wungak, H. G. Ularamu

“…Wild animals were immobilized using a combination of etorphine hydrochloride (M99® Krüger-Med South Africa) at 0.5–2 mg/kg and azaperone (Stresnil®, Janssen Pharmaceuticals (Pty.) …”
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Advanced tissue technologies of blood-brain barrier organoids as high throughput toxicity readouts in drug development by Luisa Bell, Claire Simonneau, Chiara Zanini, Elena Kassianidou, Christelle Zundel, Rachel Neff, Bernd Steinhuber, Marco Tecilla, Alex Odermatt, Roberto Villaseñor, Nadine Stokar-Regenscheit

“…Here, we developed an adapted set of orthogonal image-based tissue methods including hematoxylin and eosin staining (HE), immunohistochemistry (IHC), multiplex immunofluorescence (mIF), and Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI-MSI) to validate CIVMs for drug toxicity assessments. …”
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Association between Air Pollution and Risk of Hospital Admission for Pediatric Pneumonia in a Tropical City, Kaohsiung, Taiwan by Peng-Huei Liu, Kuo-Chen Huang, Yu-Lun Tseng, I-Min Chiu, Hsiu-Yung Pan, Fu-Jen Cheng

“…Furthermore, higher PM2.5 concentration (> 45 µg m–3) was associated with prolonged hospital LOS (OR: 0.217, 95% CI: 0.03–0.404, P = 0.023), especially for younger children (≤ 5 years). …”
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Additively manufactured ultrafine grained Aermet100 with superior mechanical property by Yanwen Liang, Jie Liu, Xiaotian Zhang, Yonghao Weng, Sheng Zhong, Tiannan Li, Peng Zhang, Chunpan Yang, Ying Xing, Jiazhe Fu, Kehong Wang

“…The results indicate that the specimens were well-formed, achieving a relative density of 99.99% through an optimal combination of process parameters: a laser power of 220 W, scanning speed of 1000 mm/s, scanning rotation of 67°, and hatch spacing of 0.07 mm.The additively manufactured Aermet100 specimens exhibited ultrafine grains with an average size of 0.4 μm. Tempering of the as-built specimens at 482 °C for 2 h resulted in the highest strength and hardness. …”
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The association between serum ferritin levels and the risk of gestational diabetes mellitus: a prospective cohort study by Shaofei Su, Shen Gao, Enjie Zhang, Jianhui Liu, Shuanghua Xie, Yue Zhang, Ruixia Liu, Wentao Yue, Chenghong Yin

“…Results The median serum ferritin level in the first trimester was 57.7 ng/mL, and 13.5% of participants developed GDM. After multivariate adjustment, the RRs and 95% CIs for incident GDM across baseline serum-ferritin quintiles were 1.099 (0.940–1.285), 1.228 (1.055–1.430), 1.186 (1.018–1.383) and 1.179 (1.017–1.367), respectively. …”
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Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis by Tim Salinger, Kai Hu, Dan Liu, Scharoch Taleh, Sebastian Herrmann, Daniel Oder, Daniel Gensler, Jonas Müntze, Georg Ertl, Kristina Lorenz, Stefan Frantz, Frank Weidemann, Peter Nordbeck

“…Laboratory parameters, medication, and prevalence of eight known cardiac comorbidities and risk factors (hypertension, diabetes, coronary heart disease, peripheral artery occlusive disease, cerebrovascular disease, renal dysfunction, body mass index ≥30 Kg/m2, and history of smoking) were analyzed. Patients were divided into slow (Pmean < 5 mmHg/year) or fast (Pmean ≥ 5 mmHg/year) progression groups. …”
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Klotho enhances stability of chronic kidney disease atherosclerotic plaques by inhibiting GRK2/PLC-β-mediated endoplasmic reticulum stress in macrophages via modulation of the ROS/... by Zhe Li, Jing Li, Lin Li, Qian Wang, Qian Zhang, Ling Tian, Chenchen Li

“…This study investigates the mechanism by which Klotho enhances the stability of atherosclerotic plaques in chronic kidney disease. apoE-/- knockout mice and C57BL/6 mice underwent 5/6 nephrectomy and then klotho-NC and klotho-mimic groups were set up to be fed a high-fat chow diet and a dummy group was created to be fed a normal chow diet. qPCR detected relative mRNA expression of klotho. Oil Red O and HE staining assessed lipid proportion in the aorta. …”
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Association of serum and local GRP78 and CHOP expressions with disease progression in patients with non-traumatic osteonecrosis of femoral head by Peng Zhang, Qing-He Ye, Wen-Xiu Zhu, Yong-Heng Zhao, Hong-Xun Zhu, Biao-Fang Wei

“…A total of 42 ONFH patients at FICAT stage 3, 40 patients at FICAT stage 4, and 49 FNF patients received total hip replacement (THR). The mRNA and protein levels of CHOP and GRP78 were elevated in necrotic area compared to the non-necrotic area of ONFH patients and the FH tissues of FNF patients with statistical significance. …”
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Puerariae Radix protects against ulcerative colitis in mice by inhibiting NLRP3 inflammasome activation by Yu Ga, Yuanyuan Wei, Qingyu Zhao, Yimeng Fan, Yannan Zhang, Zhifang Zhang, Sijia Hao, Lixia Wang, Zhifen Wang, Jinlong Han, Shuang Wu, Zhihui Hao

“…PR treatment suppressed upregulation of NOD-like receptor protein 3 (NLRP3), cysteinyl aspartate-specific proteases-1 (caspase-1), apoptosis-associated speck-like (ASC) and gasdermin D (GSDMD) at both the protein and mRNA expression levels. The addition of a small molecule dual-specifi city phosphatase inhibitor NSC 95397 inhibited the positive effects of PR. …”
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Lifestyle risk factors for overweight and obesity among rural Indian adults: a community-based prospective cohort study by Rajesh Kumar Rai, Sabri Bromage, Jan-Walter De Neve, Anamitra Barik

“…India’s nutrition transition has led to an increased burden of overweight/obesity (body mass index of ≥23 kg/m2), driven by lifestyle factors like poor diet, inactivity, and substance use, prompting public health interventions. …”
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Acute Bronchiolitis To Pediatric Inpatient Clinic In Patients Under 2 Years Old, Installed with Diagnosis Investigation of the Relationship of Bronchiolitis and Asthma by Selin Kuzucu, İpek Türktaş, Tuğba Bedir Demirdağ, Meltem Polat, Hasan Tezer, Anıl Tapısız, Nazmi Mutlu Karakaş, Ayşe Tana Aslan, Hakan Tüzün

“…The asthma risk was evaluated using the modified Asthma Predictive Index (mAPI) designed for predicting future asthma in bronchiolitis cases. …”
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Enhanced compressive strength and in vitro degradation of porous pectin/ calcium phosphate cement scaffolds by freeze casting without sintered by Hao Zhang, Yufei Tang, Xuan Zhou, Qian Liang, Yani Sun, Bo Zhang, Kang Zhao, Zixiang Wu

“…At a pectin content of 70 mg/mL, the scaffolds demonstrated a degradation rate of 13.79% within a span of 30 days. …”
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