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61461
Regenerative fibroblasts derived from autologous skin tissue for the treatment of Sjögren’s syndrome: a case report
Published 2025-01-01“…ESR, B lymphocytes, rheumatoid factor IgM, and IgA declined, while the proportion of NK cells increased, and most of the cytokines returned to normal levels. …”
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61462
3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications
Published 2025-01-01“…Moreover, the mechanical study showed excellent compressive strength (188 MPa), a high Young’s modulus (2.84 GPa), and elevated fracture toughness (9.11 MPa.m1/2). An in vitro study by MTT assay on osteoblast (MG-63) cells demonstrated no or minimal cytotoxicity at the higher concentration, 100 µg/ml after 24 h and it was found a more pronounced result at 20 µg/ml on increasing the concentration of Cu nanoparticles after incubating 72 h. …”
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61463
Bioconversion of kitchen waste by Pichia kudriavzeii SGP1 (Sudhida Gautam Parihar1)
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61464
Class III β-Tubulin Overexpression Induces Chemoresistance to Eribulin in a Leiomyosarcoma Cell Line
Published 2018-01-01“…The IC50 of eribulin was 125 times higher in the resistant cell line than in the parental cell line, and eribulin did not induce G2/M arrest in resistant cells. The resistant cell line showed increased expression of MDR1 transcript, but protein levels and functional analysis results were similar to the parental cell line. …”
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61465
Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM
Published 2025-01-01“…Analysis of the TCGA, GTEx, and UALCAN databases revealed significant differences in NTN1 expression at both the mRNA and protein levels. Prognostic value was evaluated through univariate Cox regression and Kaplan–Meier methods. …”
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61466
Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs
Published 2025-01-01“…Hydrogen-saturated saline was administered intravenously (125 mL/h) through the left internal jugular vein of pigs, and the blood hydrogen concentration was measured over time. …”
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61467
Siyonizm, Arz-ı Mev‘ûd ve Kur’ân
Published 2024-11-01“…Nuh’a isnad edilen bir mitolojik anlatımı benimseyerek, dillendirdikleri görülmektedir Kitab-ı Mukaddes eksenli metin tenkidi çalışmaları yapan uzmanlar, Yehuda merkezli seçkincilik anlayışını yansıtan Tesniye kitabının M.Ö. VII. yüzyılda Yehuda bölgesinde oluşturulduğu kanaatindedirler. …”
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61468
The role of Akkermansia muciniphila in maintaining health: a bibliometric study
Published 2025-02-01“…Among the 820 institutions involved in the research, the University of California (from the United States) and the Chinese Academy of Sciences (from China) occupied central positions. Willem M. De Vos ranked at the top, with 12 publications and 1,108 citations. …”
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61469
The association between age at menarche (AAM) and cardiovascular disease (CVD) risk factors in the MASHAD cohort study
Published 2025-01-01“…In girls who menstruated at age ≤ 11 years old, the odds of having a BMI > 28.7 kg/m2, WC > 96 cm, HC > 105 cm and WTR > 61.96 were higher than girls who menstruated at 13 years old. …”
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61470
Evaluation of the efficacy of bromfenac sodium in the treatment of dry eye disease
Published 2024-03-01“…Makukha, N.E. Kostina </p> <p> M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation </p> <p> <b>Background: </b>to date, the efficacy of anti-inflammatory treatment in dry eye disease (DED) is still relevant. …”
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61471
Engineering of SauriCas9 with enhanced specificity
Published 2025-03-01“…To validate its efficacy, we employed SauriCas9-R253A to disrupt three genes (B2M, TRAC, and PDCD1), a strategy integral to the development of allogeneic chimeric antigen receptor T cell (CAR-T) therapies. …”
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61472
Nomogram based on the log odds of negative lymph node/T stage can predict the prognosis of patients with colorectal cancer: a retrospective study based on SEER database and externa...
Published 2024-12-01“…LONT, age, sex, race, subsite, differentiation, histology, tumour size, T stage, N stage, M stage and chemotherapy were included in the nomogram. …”
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61473
Clinical comparison and genetic analysis in pheochromocytoma with primary aldosteronism
Published 2025-02-01“…Compared to 15 other patients without primary aldosteronism complications, these three patients had a greater suppression of plasma renin activity (0.2 vs. 2.3 ng/mL/h, p < 0.01) and a higher aldosterone-to-renin ratio (p < 0.01). …”
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61474
MTMR6 downregulation contributes to cisplatin resistance in oral squamous cell carcinoma
Published 2025-01-01“…Mouse xenografts derived from MTMR6-knockdown UMSCC1 cells exhibited increased resistance to cisplatin compared to controls. Conclusion Assessing mRNA levels of MTMR6 and has-miR-544a in biopsy samples could help predict cisplatin responsiveness in OSCC.…”
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61475
整合素β4调控脑血管发育
Published 2022-09-01“…方法通过逆转录PCR(RT-PCR)检测靶向<italic>itgb4</italic> mRNA序列的吗啉环(MO)在斑马鱼胚胎中的敲低效果。利用体视显微镜和激光共聚焦显微镜(laser scanning confocal microscope, LSCM)观察抑制<italic>itgb4</italic>表达后,斑马鱼胚胎脑部血管的发育变化。…”
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61476
Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study)
Published 2022-07-01“…Symptom severity will be assessed for fatigue (Checklist Individual Strength (CIS subscale fatigue severity)), pain (Rand-36/SF-36 subscale bodily pain), dyspnoea (Medical Research Council (mMRC)) and cognitive impairment (Cognitive Failure Questionnaire (CFQ)). …”
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61477
Multi-Modal Fusion of Routine Care Electronic Health Records (EHR): A Scoping Review
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61478
Wacana Gender Dalam Perjanjian Pernikahan Rifā'ah Rāfi’ Al-Ṭahṭāwī
Published 2024-08-01“…Perjanjian pernikahan yang bertujuan untuk menghormati seorang istri dibuat oleh Rifā'ah Al-Ṭahṭāwī yang ditujukan kepada istrinya Karima binti Muhammad al-Fargali pada tahun 1839 M. Penelitian ini bertujuan untuk menganalisis bagaimana perempuan ditampilkan dalam perjanjian pernikahan Rifā'ah al-Ṭahṭāwī tersebut. …”
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61479
Lignans from Patrinia scabiosaefolia improve insulin resistance by activating PI-3K/AKT pathway and promoting GLUT4 expression
Published 2023-11-01“…Western blotting experiments showed that compounds 2 and 4 up-regulated the protein expressions of p-IRS, PI-3K, p-AKT and glucose transporter 4 (GLUT4), and promoted the transcription of GLUT4 mRNA. Therefore, the mechanisms of compounds 2 and 4 were presumed to improve IR by activating PI-3K/AKT signaling pathway.…”
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61480
Involvement of the posterior limb of the internal capsule independently predicts the prognosis of patients with basal ganglia and thalamic hemorrhage
Published 2025-01-01“…An unfavorable outcome was defined as a 90-day modified Rankin Scale (mRS) of > 2. Multivariate logistic regression analysis was used to identify independent risk factors associated with unfavorable prognosis. …”
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