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61301
Fungi with potential probiotic properties isolated from Fuzhuan brick tea
Published 2022-05-01“…Of the 18 strains, 10 tolerated simulated human digestive conditions for sufficient periods in vitro: pH 2-3, 0.3%-0.5% (m/V) bile salts, and artificial gastrointestinal juices. …”
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61302
Retrospective cross-sectional study on bronchiectasis in adult Aboriginal Australians: disease characteristics and comparison with ethnically diverse global bronchiectasis registry...
Published 2025-01-01“…In comparison with international and non-Aboriginal Australian national cohorts, Aboriginal Australians were younger (median 56 years (IQR (48, 65)); however, sex distribution (55% female) and body mass index (23 kg/m2 (IQR 19.4–27)) were comparable . Smoking rates were higher at 85% compared with other registry cohorts (22–46%) as was the prevalence of comorbidities (97%): cardiovascular diseases (73%), diabetes mellitus (50%) and chronic obstructive pulmonary disease (83%) compared with other registry cohorts (4–32%; 6–14%; and 14–37%, respectively). …”
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61303
A novel histone acetylation-associated gene signature with prognostic value in Ewing sarcoma
Published 2024-12-01“…After collecting EWS patients with mRNA sequencing data from the Gene Expression Omnibus (GEO) database and a list of HARGs from previous studies, Cox regression and Least Absolute Shrinkage and Selection Operator (LASSO) regression were performed to construct a prognostic gene signature based on HARGs. …”
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61304
Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery.
Published 2025-02-01“…Tumor growth was monitored using bioluminescence imaging and mRNA-based molecular classification was used to characterize xenografts into molecular subtypes. …”
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61305
Impact of Ag Coating Thickness on the Electrochemical Behavior of Super Duplex Stainless Steel SAF2507 for Enhanced Li-Ion Battery Cases
Published 2025-01-01“…Ag is applied at five different thicknesses: 0.5, 1.0, 1.5, 2.0, and 2.5 μm. The surface conditions and electrochemical properties are then examined for each coating thickness. …”
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61306
IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury
Published 2025-02-01“…OI promoted the transformation of macrophages into M2 macrophages, and this was inhibited when TIM4 was blocked. …”
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61307
Immune-metabolic shifts in acute liver failure caused by HEV infection during pregnancy and their association with obstetric outcomes
Published 2025-02-01“…Pregnant women with (i) acute viral hepatitis, IgM HEV positive (AVH-E, n = 31, Gr.I), (ii) acute liver failure (ALF-E, n = 15, Gr.II), (iii) acute hepatitis but negative for viral infections (non-HEV, n = 30, Gr.III), and healthy (HC, n = 21, Gr.IV) were evaluated at delivery for plasma untargeted metabolomics, cytokine, and immune profiling. …”
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61308
Identification of a postoperative survival scoring index for adult liver transplantation
Published 2025-12-01“…Area under the curve (AUC) and Kaplan–Meier’s (K–M) analysis demonstrated superiority of the new index. …”
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61309
Strengthening dual-phase Mg-Li alloy through precipitation control
Published 2025-01-01“…Through precise control of precipitates, the cast Mg-8Li-3Al-2Zn alloy obtained a high specific ultimate tensile strength of 213 kN·m·kg−1. Precipitates evolution during non-isothermal aging was investigated: strip-like Mg3(Al, Zn) in β-Li → globular Mg3(Al, Zn) in β-Li →Mg/Li(Al, Zn) core–shell and nanoscale rod-like Mg3(Al, Zn) in β-Li + Laves phase in α-Mg. …”
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61310
Wet and Dry Atmospheric Depositions of Inorganic Nitrogen during Plant Growing Season in the Coastal Zone of Yellow River Delta
Published 2014-01-01“…The total atmospheric nitrogen deposition was ~2264.24 mg m−2, in which dry atmospheric nitrogen deposition was about 32.02%. …”
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61311
TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch
Published 2016-01-01“…Application of immepip (8.3–50 μM) could also induce a dose-dependent increase in intracellular Ca2+ (Ca2+i) of DRG neurons. …”
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61312
Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl4-) Induced Liver Injury in Mice
Published 2014-01-01“…The reduction of hepatic injury in the DEC-treated group was confirmed by the COX-2 and iNOS mRNA expression levels. Based on the results of the present study, DEC can be used as a potential anti-inflammatory drug for chronic hepatic inflammation.…”
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61313
Group 2 Innate Lymphoid Cells Participate in Renal Fibrosis in Diabetic Kidney Disease Partly via TGF-β1 Signal Pathway
Published 2019-01-01“…Moreover, the IL-4Rα and IL-13Rα1 mRNA in HK2 cells were increased followed by high glucose alone or combined with IL-4 or IL-13, but the differences were not statistically significant (P>0.05). …”
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61314
Residual Characteristics and Dietary Risk Assessment of Dinotefuran and Tolfenpyrad in Tea Processing
Published 2025-01-01“…In the range of 0.005–0.500 µg/mL, a good linear relationship was obtained between the concentrations of dinotefuran and its metabolites as well as tolfenpyrad and their response peak areas (R2 > 0.99). …”
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61315
Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides
Published 2025-02-01“…Finally, coinjection of LBDB, Vibrio alginolyticus and Staphylococcus aureus in vivo improved the survival of M. japonicus, demonstrating the promising therapeutic role of LBDB for treating infectious disease. …”
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61316
Digital Health Solutions for Cardiovascular Disease Prevention: Systematic Review
Published 2025-01-01“…The literature search used the string with terms like “digital health,” “mHealth,” “mobile health,” “text message,” “short message service,” “SMS,” “prevention,” “prevent,” “cardiovascular disease,” “CVD,” etc. …”
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61317
Unveiling the Potency of Gardenia Extract Against <i>H. pylori</i>: Insights from In Vitro and In Vivo Studies
Published 2025-01-01“…Thirty-five male Sprague–Dawley rats were inoculated with <i>H. pylori</i> (10<sup>8</sup>–10<sup>10</sup> colony-forming unit/mL) and divided into five groups. Each group was treated with various doses of the extract (98–395 mg/kg). …”
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61318
Safety and Intranasal Retention of a Broad-Spectrum Anti-SARS-CoV-2 Monoclonal Antibody SA55 Nasal Spray in Healthy Volunteers: A Phase I Clinical Trial
Published 2024-12-01“…Background: A broad-spectrum anti-SARS-CoV-2 monoclonal antibody (mAb), SA55, is highly effective against SARS-CoV-2 variants. …”
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61319
Single-cell profiling transcriptomic reveals cellular heterogeneity and cellular crosstalk in breast cancer lymphatic node, bone, and brain metastases
Published 2025-01-01“…We identified five T cells (T memory, CD8 + T cells, regulatory T cells, natural killer cells, CD4 + T cells), three B cells (naïve B cells, memory B cells, plasma B cells), and five cancer-associated fibroblasts (CAFs) subpopulations (Smooth muscle cells (SMC), pericyte, antigen-presenting CAFs (apCAFs), proliferative CAFs (pCAFs), and matrix CAFs (mCAFs)). Notably. pCAFs dominated breast cancer with lymphatic node, bone, and brain metastasis. …”
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61320
Microstructures and mechanical properties of a 30CrNi2MoV steel/GH4098 joint produced by hot-compression bonding
Published 2025-03-01“…Owing to the mutual diffusion of GH4098 and 30CrNi2MoV, the bonding interface becomes an interface band where Al2O3/Ti(C, N) is distributed on the side near GH4098 and Ti(C, N)/M23C6 is distributed on the side near 30CrNi2MoV. …”
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