Antarctic krill antioxidant peptides show inferior IgE-binding ability and RBL-2H3 cell degranulation by Jie Ding, Chunyan Zhu, Pengfei Jiang, Libo Qi, Na Sun, Songyi Lin

“…And N2-2 had a higher EC50 value of (5.29 ± 0.95) ng/mL (P < 0.05) in cell degranulation assay, which was about 13.80 times that of Antarctic krill. …”
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Abono líquido orgánico acelerado elaborado a partir de efluentes de la industria de la palma aceitera by Juan Carlos Jaulis Cancho, Juan Juscamaita, Ana Martínez Varillas, Marilyn Aurora Buendía Molina, Enrique Raúl Adama Rojas, Eduardo Leuman Fuentes Navarro

“…El T4 obtuvo el mejor resultado con 4,3 de pH; 28,54 dS*m-1 en Conductividad Eléctrica (CE) y el mayor contenido de nitrógeno (9560,46 mg*L-1), fósforo (1620,79 mg*L-1), potasio (6787,50 mg*L-1), materia orgánica 262,01 g*L-1 y sólidos totales 302,80 g*L-1. …”
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Optimization of fermentation conditions to increase the production of antifungal metabolites from Streptomyces sp. KN37 by Xiaoyue Yang, Lijing Yuan, Muhammad Zeeshan, Chuntian Yang, Wen Gao, Guoqiang Zhang, Chunjuan Wang

“…Subsequently, optimization by the response surface methodology yielded the final fermentation conditions as: millet 20 g/L, yeast extract 1 g/L, K2HPO4 0.5 g/L, rotation speed 150 r/min, temperature 25 °C, initial pH 8, fermentation time 9 d, inoculation amount 4%, liquid volume 100 mL. The antifungal effect of the optimized strain fermentation dilution was significantly enhanced, and the antifungal rate of R. solani increased from 27.33 to 59.53%, closely aligning with the predicted value of 53.03%. …”
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Anticarcinogenic cationic peptides derived from tryptic hydrolysis of β-lactoglobulin by Eman Ibrahem, Ali Osman, Hefnawy Taha, Mohamed F. Abo El-Maati, Basel Sitohy, Basel Sitohy, Mahmoud Sitohy

“…The in vitro anticancer activity against Mcf-7, Caco-2, and A-549 human cancer cell lines proliferation by MTT assay recorded IC50% at 42.8, 76.92, and 45.93 μg/mL, respectively. Treating each cell line with IC50% of the hydrolysate for 24 h increased the apoptosis by enhancing the expression of caspase-9 by 5.66, 7.97, and 3.28 folds over the untreated control and inhibited angiogenesis by reducing VEGFR-2 expression by about 56, 76, and 70%, respectively, indicating strong anticancer and antiangiogenic actions on human cancer cells. …”
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Cardiac Resynchronization Therapy Reduces Metaboreflex Contribution to the Ventilatory Response in Heart Failure Population by Jérémie Jaussaud, Laurie Aimable, Pierre Bordachar, Pierre Dos Santos, Laurent Barandon, Philippe Ritter, Raymond Roudaut, Hervé Douard

“…Patients had enhanced VE/VCO2 slope (40±9) and an evident metaboreflex contribution to the high ventilatory response (ΔVE: 3±4 L/min; 𝑃=0.05, ΔRR: 4.5±4/min; 𝑃=0.003 and ΔVE/VCO2: 5.5±4; 𝑃=0.007). 6 months after CRT implantation, NYHA class, LVEF, peak VO2 and VE/VCO2 were significantly improved (1.4±0.5; 𝑃<0.001, 42±7%; 𝑃<0.001, 16.5±3 mL/kg/min; 𝑃=0.003; 33±10; 𝑃=0.01). Metaboreflex contribution to VE, RR, and VE/VCO2 was reduced compared with baseline (𝑃=0.08, 𝑃=0.01 and 𝑃=0.4 resp.). …”
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MỘT SỐ PHƯƠNG PHÁP PHÂN TỬ TRONG CHẨN ĐOÁN PASTEURELLA MULTOCIDA VÀ MANNHEIMIA HAEMOLYTICA Ở ĐỘNG VẬT by Cong Tuan Le, Thi Xuan Tuy Ho, Thi Dieu The Nguyen, Thi Thu Thao Nguyen, Thi Ngoc Han Hoang, Thi Diem Nguyen, Van Phu Nguyen, Huu Tho Nguyen, Thi Oanh Nguyen, Thi Kim Cuc Nguyen, Xuan Huy Nguyen

“… P. multocida và M. haemolytica là những tác nhân chính gây ra tụ huyết trùng trên nhiều loại gia súc, gia cầm dẫn tới những thiệt hại kinh tế lớn cho ngành chăn nuôi. …”
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Effect of Transcranial Direct-Current Stimulation and Task-Oriented Training on Electroencephalography-Based Motor Recovery Chronic Stroke: A Randomized Clinical Trial by Maryam Zolghadr, Shohreh Noorizadeh Dehkordi, Javad Sarrafzadeh, Saeed Talebian, Hassan Haddadzade Niri, Marzieh Yassin

“…Materials and Methods: Thirty chronic hemiparetic stroke survivors were randomly assigned to receive real or sham stimulation targeting the primary motor cortex (C3/C4) at 2 mA for 20 minutes and TOT daily over 15 sessions. …”
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Festivales de música y marketing experiencial: efectos para marca, organizador y espectador by Mónica Valderrama Santomé, Verónica Crespo-Pereira

“…Se aporta una clasificación propia sobre los efectos del patrocinio en este tipo de eventos sobre las marcas, asistentes y festivales. Clasificación JEL: M31…”
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Effect of Zirconium Oxide and Zinc Oxide Nanoparticles on Physicochemical Properties and Antibiofilm Activity of a Calcium Silicate-Based Material by Juliane Maria Guerreiro-Tanomaru, Adinael Trindade-Junior, Bernardo Cesar Costa, Guilherme Ferreira da Silva, Leonardo Drullis Cifali, Maria Inês Basso Bernardi, Mario Tanomaru-Filho

“…The analysis was conducted by using the number of colony-forming units (CFU/mL). The compressive strength was performed in a mechanical testing machine. …”
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Demography and homing behavior in the poorly-known Philippine flat-headed frog Barbourula busuangensis (Anura: Bombinatoridae) by Marta Miñarro, Patricia Burrowes, Claudia Lansac, Gregorio Sánchez-Montes, Leticia E. Afuang, Ignacio De la Riva

“…CMR data confirmed site fidelity, and translocation experiments revealed that frogs have the ability to home when displaced 10–50 m upstream and downstream from their original capture site. …”
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Dietary secoisolariciresinol diglucoside ameliorates high-fat diet-induced atherosclerosis via regulating immunological inflammation and reshaping gut microbiota in ApoE-/- mice by Yiwei Li, Jing Wang, Jian Liu, Ting Wang, Yuanyuan Liu, Yajuan Liu, Li Guo, Zhixia Bai, Wenke Shen, Ru Yan, Huiyan Ma, Juan Liu, Hao Wang, Xiaoxia Zhang

“…It also reduced chronic systemic/vascular inflammatory cytokines and in situ macrophages (Mψs). Due to the critical role of gut-vascular axis in AS, multi-omics analysis revealed that the modulation of gut microbiota and metabolism, including reductions in Firmicutes, Intestinimonas, Bilophila, Oscillibacter and Negativibacillus and increases in linoleic acid and 12,13-DHOME, may contribute to the attenuation of SDG on gut dysbiosis. …”
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Reconstruction of Polyhalite Ore-Formed Temperature from Late Middle Pleistocene Brine Temperature Research in Kunteyi Playa, Western China by Jun Li, Wenxia Li, Weiliang Miao, Qiliang Tang, Yongshou Li, Xiaolong Yuan, Qingyu Hai, Yongsheng Du, Xiying Zhang

“…However, under the overall low-temperature background, polyhalite seems to be easily enriched at relatively high temperature; for example, the content of polyhalite is generally high in the first relatively dry and hot salt-forming period, and the brine temperature at the peak stage of polyhalite at 45 m is relatively high, which indicates that the high temperature conditions promote the formation of polyhalite in KSL. …”
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Methionine-driven methylation modification overcomes plasmid-mediated high-level tigecycline resistance by Dan Fang, Tianqi Xu, Fulei Li, Yue Sun, Jingyi Sun, Yanqing Yin, Haijie Zhang, Zhiqiang Wang, Yuan Liu

“…Moreover, Met accelerates the conversion to S-adenosyl-L-methionine, an essential methyl donor, thereby enhancing 5mC methylation modification in the promoter region of tet(X4) gene and reducing its expression. …”
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Oxidative Stress and Risk of Dementia in Older Patients with Depression: A Longitudinal Cohort Study Using Plasma Biomarkers by Yoo-Jin Jang, Min-Ji Kim, Su-Jin Lee, Shinn-Won Lim, Doh-Kwan Kim

“…For clinical applicability, patients with plasma nitrotyrosine levels ≥170 nM as the cut-off value had a 5.14-fold increased risk of AD (adjusted HR, 5.14; 95% CI, 2.02–13.07; <i>p</i> = 0.0006). …”
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Lipid mediators in post-mortem brain samples from patients with Alzheimer's disease: A systematic review by Aidan D. Tyrrell, Giulia Cisbani, Mackenzie E. Smith, Chuck T. Chen, Yue-Tong Chen, Raphael Chouinard-Watkins, Kathryn E. Hopperton, Ameer Y. Taha, Richard P. Bazinet

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Valproic acid targets IDH1 mutants through alteration of lipid metabolism by Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum

“…VPA inhibited the transcription of lipogenic genes and these lipogenic genes showed significant decreases in promoter chromatin accessibility only in the IDH1 MT glioma cell lines tested. VPA inhibited the mTOR pathway and a key lipogenic gene, fatty acid synthase (FASN). …”
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Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS by Jia-Li Liang, Jia-Zhen Wu, Yu-Hong Liu, Zhen-Biao Zhang, Qi-Duan Wu, Han-Bin Chen, Yan-Feng Huang, Yao-Xing Dou, Jiang-Tao Zhou, Zi-Ren Su, Janis Ya-Xian Zhan

“…PAO was also shown to significantly downregulate the protein and mRNA expressions of cyclooxygenase-2 (COX-2) and inducible nitric-oxide synthase (iNOS). …”
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大麻素1型受体在实验性自身免疫性脑脊髓炎小鼠中的 动态表达及其作用

“…EAE 和特异性CB1R抑制剂(SR141716A,SR1)干预组小鼠的神经功能缺损症状和体质量变化;用real time PCR检测CB1R mRNA表达;Western blot和荧光免疫组织化学法检测CB1R蛋白表达;用ELISA法检测细胞因子IL-1β?…”
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双波长等吸收紫外分光法测定玻璃体内苏拉明浓度

“…(97.43±0.01) %;设计标准曲线的最低质量浓度45 μg/mL;其日内?日间相对标准差分别为14.14%?15.94%,检验回收率为(94.92±0.01) %;常温组样品,8 h及以内稳定性尚好,之后不稳定?…”
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Preparation and Electrochemical Characterization of Y-Doped Li_1.3Al_0.3Ti_1.7(PO₄)₃ Solid Electrolytes for Lithium-Metal Batter... by Zhongran Yao, Fen Qi, Qiang Sun, Lin Ye, Xiaowei Yang, Guojie Chao, Pei Tang, Kongjun Zhu

“…When paired with the NCM811 cathode, the Li/LAYTP-0.03/NCM811 cell exhibited outstanding electrochemical performance: a high capacity of 155 mAh/g was achieved at 0.2C after 50 cycles with a Coulombic efficiency of approximately 100%, indicating highly reversible lithium plating/stripping facilitated by the LAYTP-0.03 electrolyte. …”
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