Alginate-Based Hydrogels with Amniotic Membrane Stem Cells for Wound Dressing Application by Fitriani N, Wilar G, Narsa AC, Elamin KM, Wathoni N

“…Nurul Fitriani,1,2 Gofarana Wilar,3 Angga Cipta Narsa,2 Khaled M Elamin,4 Nasrul Wathoni1 1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia; 2Pharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda, 75119, Indonesia; 3Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, 45363, Indonesia; 4Graduate School of Pharmaceutical Sciences, Kumamoto University, Chuo-ku, Kumamoto, 862-0973, JapanCorrespondence: Nasrul Wathoni, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia, Tel/Fax +6222 842 888888, Email nasrul@unpad.ac.idObjective: Chronic wounds are a common clinical problem that necessitate the exploration of novel regenerative therapies. …”
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Exploring individual differences in online and face-to-face help-seeking intentions in case of impending mental health problems: The role of adult attachment, perceived social supp... by Jennifer Apolinário-Hagen, Annina Trachsel Dugo, Lisa Anhorn, Britta Holsten, Verena Werner, Simone Krebs

“…Methods: Data was collected from 301 adults from the German-speaking general population (age: M = 34.42, SD = 11.23; range: 18 - 65 years; 72.1% female) through an anonymous online survey. …”
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The Small Mobile Ozone Lidar (SMOL): instrument description and first results by F. Chouza, T. Leblanc, P. Wang, S. S. Brown, K. Zuraski, K. Zuraski, W. Chace, W. Chace, W. Chace, C. C. Womack, C. C. Womack, J. Peischl, J. Peischl, J. Hair, T. Shingler, J. Sullivan

“…An additional comparison with nearby surface ozone measuring instruments indicates unbiased measurements by the SMOL lidars down to 200 m a.g.l. Further comparison with the Goddard Earth Observing System Composition Forecast (GEOS-CF) model suggests that such lidars are a critical tool to perform model validation and can potentially be used for assimilation to air quality forecasts.…”
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Assessment of Thyroid Auto-antibodies in Euthyroid Infertile Women with Polycystic Ovarian Syndrome - A Cross-sectional Analytical Study by K. H. Anusha, Chitra Thyagaraju, H Nandeesha

“…Anti-TG antibodies of >100 U/mL were seen in 23 patients (34.3%) in PCOS group in comparison to two patients (3%) in non-PCOS group (P = 0.001). …”
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Effects of diesel exhaust inhalation on cognitive performance in human volunteers: A randomized controlled crossover study by Jason Curran, A.J. Hirsch Allen, Christopher F. Rider, Robin Shutt, Chris Carlsten

“…Volunteers were exposed to two conditions for 120 min each, on separate order-randomized occasions: filtered air (FA) and DE (300 µg/m3 PM2.5) at the Air Pollution Exposure Laboratory (APEL) at Vancouver General Hospital (VGH). …”
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Development of High-performance Proton Transfer Reaction Time-of-Flight Mass Spectrometer by Chun-guang XIE, Ji-yang ZHANG, Tong YANG, Yu-liang HUANG, Shu-guang XIE, Hui ZHU, Jing-xuan SUN, Ping CHENG

“…Experimental tests showed that the system’s resolution (full width half maximum, FWHM) is better than 2 069 (for toluene), with the detection limit of 0.36 μg/m3, a linear range of 4 orders of magnitude, and a linear correlation coefficient (R2) of 0.991. …”
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Isolation, identification and characteristics of Aeromonas sobria from diseased rainbow trout (Oncorhynchus mykiss) by Li-Ping Liu, Li-Ping Liu, Ying-Dong Fang, Peng-Tian Kang, Xiang-Yun Gao, Guo-Wei Zhang, Jing Pan, Jia Lu, Ji-Xing Liu, Wang-Dong Zhang

“…The clinical signs of the diseased rainbow trout in the experimental infection were consistent with those in the farm, and the LD50 was 1.0 × 106.6 CFU/mL. The histopathological lesions in the gills, heart, liver, spleen and intestines were mainly extensive hemorrhage. …”
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Analisis Buku “Mari Belajar Matematika” Karya Dewi Nuharini dan Sulis Priyanto Tahun 2017 by Arum Weni, Ryky Mandar Sary, Veryliana Purnamasari

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EVALUATION OF THE ADAPTIVE PROPERTIES OF SPRING BARLEY VARIETIES ACCORDING TO THEIR YIELD CAPACITY IN THE ENVIRONMENTS OF THE NEAR-IRTYSH AREA IN OMSK PROVINCE by P. N. Nikolaev, P. V. Popolzukhin, N. I. Anisimov, O. A. Yusova, I. V. Safonova

“…The experimental part of the work was  carried out during 2011-2017, on the experimental fields of the  Siberian Research Institute of Agriculture, RAAS, located in the  southern forest-steppe in the vicinity of Omsk. The plot area was 10  m2, with 4 repetitions. The sowing rate was 4 million live grains per  1 hectare. …”
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Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice by Lijun Zou, Fen Lin, Jinying Wen, Jinyu Huang, Yue Tan, Hui Huang, Gonghua Hu

“…In contrast, the highest dose (50.0 mg/kg) resulted in elevated liver enzyme levels, indicative of liver damage, while lipid levels decreased. Notably, the mRNA or protein levels of SCD1 were upregulated in response to the lower doses of HQ (12.5 and 25.0 mg/kg), whereas AMPK activation and enhanced autophagy were observed in the 50.0 mg/kg HQ-treated group, reflecting an energy stress response. …”
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Pengembangan Media Pembelajaran Matematika Electronic Snake and Ladder Pada Game-Based Learning by Arif Achmad Syaikhu, Yuniar Ika Putri Pranyata, Trija Fayeldi

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Analisis Impedansi Bioelektrik (BIA) pada Atlet Para-Panahan Pria dan Wanita: Sebuah Studi Komparatif by Idya Putra Harjianto, Nur Subekti, Pungki Indarto

“…Penelitian ini menggunakan studi komparatif dengan sampel 5 atlet para-panahan (putra, n=3; putri, n=2) berusia 31,40±10,11 tahun, tinggi badan 161,40±9,84 cm, berat badan 69,20±5,93 kg, BMI 26,60±1,66 kg/m2, dan pengalaman bermain 7,20±1,79 tahun. Peserta menjalani tes dan pengukuran komposisi tubuh menggunakan perangkat InBodyS10 yang terdiri dari komposisi air tubuh, air tubuh segmental, analisis lemak otot dan obesitas, serta laju metabolisme basal. …”
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Dynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors by Saima Rashid, Abdul Bariq, Ilyas Ali, Sobia Sultana, Ayesha Siddiqa, Sayed K. Elagan

“…By taking into account the modified Atangana–Baleanu–Caputo (mABC) fractional difference operator, we develop an analytical framework for an outbreak caused by MPXV and broaden it to accommodate the fractional scenario. …”
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A systematic literature review to evaluate the cardiac and cerebrovascular outcomes of patients with Fabry disease treated with agalsidase Beta by Gavin Y. Oudit, Gavin Y. Oudit, Pronabesh DasMahapatra, Nicole Lyn, Florence R. Wilson, Adekemi Adeyemi, Chae Sung Lee, Ana Crespo, Mehdi Namdar

“…Significant reductions in cardiac mass were demonstrated after 1 year of treatment in a single-arm study using cardiac MRI [left ventricular mass (LVM) 193–178 g; LVM index 102–94 g/m2; both p < 0.05]. Rates of composite cardiac events (3.8%–24.0%; four studies, follow-up 2–10 years) and cerebrovascular events (0.0%–18.9%; 12 studies, follow-up 1–10 years) were numerically lower than rates for placebo (follow-up 3 years).ConclusionLiterature over the last 20 years indicates that agalsidase beta treatment may lead to stabilization or regression of cardiac structural thickness and mass, and reduction in cardiac and cerebrovascular events relative to placebo.…”
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Chemical Composition Characteristics and Source Apportionment of PM2.5 in Ceramic Industrial Base during Winter by Xiang Tu, Xiaozhen Fang, Hansun Fang, Changlin Ye, Zugen Liu, Xuehui Jia, Dan He, Jinliang Wang, Hong Huang, Changwei Zou, Chenglong Yu

“…The results showed that the average PM2.5 concentration during sampling period was 134 ± 74.7 µg m−3, which exceeding World Health Organization (WHO) Air Quality Guidelines levels. …”
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A Study on the Safety and Efficacy of an Innovative Hydrophilic Dialysis Membrane by Francisco Maduell, Victor Joaquín Escudero-Saiz, Elena Cuadrado-Payán, Maria Rodriguez-Garcia, Miquel Gómez, Lida María Rodas, Néstor Fontseré, Maria del Carmen Salgado, Gregori Casals, Nayra Rico, José Jesús Broseta

“…The Toraylight NV dialyzer has great potential for efficacy but should be used at the optimal convective volume (Qi not exceeding 75 mL/min or FF not exceeding 25%) to avoid excessive albumin loss.…”
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Comprehensive Analysis of VOCs in an Industrial Harbor City: Spatiotemporal Distribution, Health Risk, and Potential Sources by Thi-Hieu Le, Chung-Shin Yuan, Chitsan Lin, Zhi-Ping Hsu, I-Hsin Hsu, Lin-Chi Wang

“…OFP results indicated that toluene was primary OFP contributor, accounting for an average of 30.4%, followed by C2-VOCs at 16.2% and m/p-xylenes at 12.5%, collectively contributing nearly 60% to OFP. …”
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人源饲养层对人胚胎干细胞生长的影响

“…【目的】 选择最佳人源饲养层,并检测不同组织来源的人源饲养层细胞碱性成纤维细胞生长因子(bFGF)的分泌情况,探讨其水平与人胚胎干细胞(hESCs)生长是否相关65377; 【方法】 原代培养包皮真皮65380;子宫内膜基质65380;绒毛65380;输卵管65380;胎儿真皮65380;胎儿肌肉及胎鼠成纤维细胞(MEFs);按组织来源分为7组(MEFs为对照),同期接种同一株hESCs,从饲养层细胞密度65380;丝裂霉素作用时间等,寻找不同饲养层适合hESCs生长的最佳条件;按人体组织分6组,ELISA方法检测各种人源饲养层细胞分泌的bFGF65377; 【结果】 根据饲养层细胞生长特性,饲养层从优到劣依次为:包皮65380;子宫内膜65380;绒毛65380;输卵管65380;胎皮65380;胎肌;根据hESCs生长状况,饲养层排序为:包皮65380;输卵管65380;子宫内膜65380;绒毛65380;胎肌65380;胎皮65377;输卵管65380;包皮65380;绒毛65380;胎肌65380;子宫内膜65380;胎皮分泌的bFGF(pg8226;10-58226;mL-1)分别为13.23 ± 3.39,1.99 ± 0.17,1.40 ± 0.17,2.02 ± 1.59,0.38 ± 0.28,0.29 ± 0.2965377;输卵管与其它组织细胞分泌的bFGF差异均有统计学意义(P < 0.01);包皮65380;绒毛65380;胎肌之间差异无统计学意义(P > 0.05),与子宫内膜65380;胎皮差异有统计学意义(P < 0.05);子宫内膜与胎皮之间差异无统计学意义(P > 0.05)65377; 【结论】 包皮来源的饲养层最佳,输卵管细胞分泌的bFGF量最高,饲养层细胞自身分泌的bFGF和hESCs生长无必然相关性65377;…”
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清开灵注射液对小鼠T细胞行为和DTH的影响 by 赵令斋, 曾耀英, 黄秀艳, 曾祥凤, 侯会娜, 尹乐乐

“…【目的】 研究清开灵注射液(QKL)对小鼠T细胞体外活化65380;增殖65380;细胞周期和迟发型超敏反应(DTH)的影响,探讨其免疫调节作用及机制65377;【方法】 不同浓度的QKL作用于小鼠淋巴细胞4 h后,加入刀豆蛋白A (ConA)刺激,于不同时间点收获细胞,利用流式细胞仪检测T细胞的活化65380;增殖和细胞周期分布情况;将小鼠分为正常对照组65380;二硝基氟苯(DNFB)诱导的DTH模型组和QKL治疗组,通过分析小鼠脾脏指数和耳朵肿胀率评价QKL对DTH的影响65377;【结果】 ConA刺激12 h后,T细胞表面CD69表达率为63.1% ± 1.3%,QKL下调CD69的表达,加入浓度为1/128065380;1/320和1/80的QKL后,CD69表达率依次降为56.2% ± 2.4%65380;51.9% ± 2.8%和39.1% ± 1.4%,与ConA对照相比,差异有统计学意义(P < 0.05);各浓度QKL明显降低ConA刺激的细胞增殖指数,且呈一定的浓度依赖性65377;对细胞周期分布的影响表现为:QKL增加ConA激活的细胞中处于S期和G2/M期的细胞数目,降低处于G0/G1期的细胞数目;体内应用QKL治疗小鼠DTH的结果为:QKL治疗组小鼠脾脏指数为4.96 ± 0.90,与模型组(脾脏指数为5.78 ± 0.85)相比, P < 0.05; 发病耳的肿胀率为28.4% ± 4.2%,与模型组(肿胀率为42.4% ± 4.6%)相比,P < 0.0165377;【结论】 QKL是一种有效的负向免疫调节剂,能抑制体内外的免疫反应,抑制T细胞的活化和增殖可能是其作用机制之一65377;…”
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Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights by Lingxia Wu, Chenxiaoxiao Liu, Weicai Hu

“…Databases like GEPIA2, HPA, MEXPRESS, and miRNet were employed for expression, survival, methylation, and miRNA-mRNA network analyses. We investigated the expression and promoter methylation landscape of MMPs in SKCM cell lines, revealing significant (p-value < 0.05) up-regulation of MMP1, MMP7, MMP9, MMP10, MMP11, MMP12, MMP13, MMP14, and MMP25, alongside down-regulation of MMP2, MMP3, and MMP21. …”
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