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60801
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60802
Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k-AKT...
Published 2025-01-01“…In addition, the CHSe NPs modulated the immune microenvironment of ALI by reversing M1 macrophage polarization, downregulating the expression levels of pro-inflammatory cytokines (IL-1β, IL-6, TNF-a), nitric oxide synthase (iNOS), and myeloperoxidase (MPO), and upregulating anti-inflammatory cytokine (IL-10) levels, thereby alleviating excessive inflammation and decreasing neutrophil infiltration. …”
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60803
纳米孔长读测序鉴定肝癌细胞中低氧特异性转录本
Published 2024-01-01“…结论纳米孔长读长测序技术的应用,不仅成功捕捉到了低氧条件下mRNA的特征性表达模式及特异性转录本,同时为深入探索低氧微环境下的转录组复杂性提供了强有力的技术支撑。…”
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60804
IL-10 and socs3 Are Predictive Biomarkers of Dengue Hemorrhagic Fever
Published 2017-01-01“…Amounts of interleukins IL-2, IL-4, IL-6, and IL-10, interferon- (IFN-) γ, and tumor necrosis factor- (TNF-) α were quantified by flow cytometry, and the relative expression of socs1 and socs3 mRNA was quantified by real-time RT-PCR. Results. …”
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60805
Construction of a Novel Necroptosis-Related Signature in Rat DRG for Neuropathic Pain
Published 2025-01-01“…This study aims to identify a gene signature related to necroptosis in DRG that can predict neuropathic pain.Methods: The mRNA expression profiles associated with neuropathic pain (GSE24982 and GSE30691) were acquired from the Gene Expression Omnibus (GEO) database. …”
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60806
Identification and the molecular mechanism of novel duck liver-derived anti-inflammatory peptides in lipopolysaccharide-induced RAW264.7 cell model
Published 2024-11-01“…In the lipopolysaccharide-induced RAW264.7 cell model, the release of NO, TNF-α, and IL-6 and the mRNA expression of inflammatory factors (TNF-α, IL-6, COX-2, and NF-κB) were significantly inhibited by these peptides. …”
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60807
Effect of the Hydroethanolic Extract of Bixa orellana Linn (Bixaceae) Leaves on Castor Oil-Induced Diarrhea in Swiss Albino Mice
Published 2019-01-01“…To induce diarrhea, animals orally received castor oil (1 mL/100 g bw). To determine the effective doses, each mouse received, 30 minutes after the administration of castor oil, one of the single oral doses of hydroethanolic extract of Bixa orellana leaves: 0, 25, 50, 100, and 200 mg/kg bw. …”
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60808
Mine Flooding History of a Regional Below-Drainage Coalfield Dominated by Barrier Leakage (1970–2014)
Published 2019-01-01“…As protective pumping ceased, the Fairmont Pool rose to a water level 3 m higher than surface drainage elevation and in 1997 discharged from an undermined section of Buffalo Creek near the Monongahela River. …”
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60809
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60810
Annealing temperature modify of crystalline structure, magnetic properties and antibacterial performance in nickel substituted cobalt ferrite nanoparticles utilizing natural-fine-s...
Published 2024-12-01“…The XRD results showed that the whole Ni-CFO nanoparticles established an inverse spinel face center cubic (fcc) order according to space group Fd-3m for both NiCFO-fs and NiCFO-pa. There was no additional peak, indicating that Ni2+ cations successfully substituted in cobalt ferrite nanoparticles. …”
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60811
Scalable production of bio-calcium oxide via thermal decomposition of solid - hatchery waste in a laboratory-scale rotary kiln
Published 2025-01-01“…The results also indicated that the production yield of bio-CaO decreased to 17.7% with a decrease in the raw material particle size from 3.3 mm to 250 μm. Moreover, the production of bio-CaO with eggshells containing eggshell membrane decreases the purity of calcium oxide by about 0.7–1.0%. …”
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60812
子宫动脉栓塞术对子宫内膜整合素β3含量影响的实验研究
Published 2011-01-01“…UAE组动物应用三丙烯微球(Embosphere,40~120µm及100~300µm)行双侧子宫动脉栓塞术。A1、A2、A3组动物分别于UAE后16~30d、31~45d及46~60d内获取子宫标本。…”
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60813
LoSI: Large Scale Location Inference Through FM Signal Integration and Estimation
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60814
Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses
Published 2025-01-01“…Notably enriched pathways included neuroactive ligand‐receptor interaction, mechanistic target of rapamycin (mTOR) signaling pathway, nicotine addiction, and dopaminergic synapse. …”
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60815
Review and External Evaluation of Population Pharmacokinetic Models for Vedolizumab in Patients with Inflammatory Bowel Disease: Assessing Predictive Performance and Clinical Appli...
Published 2024-12-01“…Simulation analysis further demonstrated that the median VDZ concentration remains above 12 μg/mL at week 22 during maintenance treatment for approximately 45–60% of patients with the best-case covariate combinations and an 8-week dosing frequency. …”
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60816
Predicting the Most Deleterious Missense Nonsynonymous Single-Nucleotide Polymorphisms of Hennekam Syndrome-Causing CCBE1 Gene, In Silico Analysis
Published 2021-01-01“…Structural homology-based methods and sequence homology-based tools revealed that 8.8% of the nsSNPs are pathogenic. SIFT, PolyPhen2, M-CAP, CADD, FATHMM-MKL, DANN, PANTHER, Mutation Taster, LRT, and SNAP2 had a significant score for identifying deleterious nsSNPs. …”
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60817
双侧多焦点与单眼视设计单焦点人工晶状体眼的立体视功能
Published 2012-01-01“…多焦组双眼植入Array多焦点人工晶状体,共27例;单焦组双眼植入单焦点人工晶状体,共26例;单眼视组,一眼按术后裸眼正视,另一眼按术后裸眼为-1.75 m-1近视植入相应度数单焦点人工晶状体,共31例?记录远?近视力及远?近立体视锐度? 【结果】 术后多焦组和单焦组最佳矫正远视力(LogMAR,以下同)分别为-0.03 ± 0.08和-0.03 ± 0.07,单眼视组拟正视眼裸眼远视力是-0.04 ± 0.08,三组比较P > 0.05;术后单焦组和多焦组近视力及单眼视组拟视近眼裸眼近视力分别为0.52 ± 0.14?…”
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60818
Comparison of In Vitro Biotransformation of Olive Polyphenols Between Healthy Young and Elderly
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60819
Inhibition of Ultraviolet B-induced Apoptosis in Fibroblasts by Human Umbilical Cord Blood Mesenchymal Stem Cell Conditioned Media via the Phosphatidylinositol-3-Kinase/Akt Pathway
Published 2025-01-01“…NIH3T3 cells were pretreated with/without 50 μM LY294002, treated with/without 10% CM-hUCB-MSC, and then irradiated with/without UVB. …”
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60820