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60721
绿海龟细菌性疾病流行病学调查
Published 2022-01-01“…对溶藻弧菌进行攻毒与病龟组织切片分析,结果显示,溶藻弧菌对中华草龟(<i>Chinemys reevesii</i>)具有较高的致病力,其LD<sub>50</sub>为2.99×10<sup>6</sup>~2.59×10<sup>8</sup> cfu/mL; 分离的溶藻弧菌可以引起中华草龟肠道、肝脏和脾脏组织病理损伤。进一步分析45株病原菌对水产养殖允许使用的6种抗生素的耐药性,结果显示分离菌株对盐酸多西环素、复方新诺明具有较高的耐药性,硫酸新霉素、氟苯尼考、恩诺沙星和环丙沙星可以作为绿海龟感染的应急用药。…”
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60722
hCeO2@CA-074Me Nanoparticles Alleviate Inflammation and Improve Osteogenic Microenvironment by Regulating the CTSB-NLRP3 Signaling Pathway
Published 2025-01-01“…The osteogenic ability was evaluated using ALP staining, ALP quantitative analysis, alizarin red staining, and RT-PCR analysis.Results: Findings clearly demonstrated that hCeO2@CA-074Me NPs could effectively reduce the production of ROS and inhibited CTSB-NLRP3 signal pathway, thereby significantly attenuating the damage caused by the cellular inflammatory response. hCeO2@CA-074Me NPs could also induce the polarization of macrophages towards anti-inflammatory M2 phenotype. Additionally, results confirmed that hCeO2@CA-074Me NPs could inhibit inflammation and ameliorate osteogenic microenvironment, thus promoting the osteogenesis of MC3T3-E1 cells.Conclusion: The synthetic hCeO2@CA-074Me NPs could able to modify the osteogenic microenvironment under inflammatory conditions by simultaneously inhibiting the CTSB-NLRP3 signaling pathway and regulating the macrophage phenotype through their ability to scavenge ROS. …”
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60723
The prevalence of optrA-carrying Enterococci in the vaginal micro-ecology of pregnant women in late pregnancy
Published 2025-01-01“…Luria-Bertani broth and florfenicol (10 µg/mL) were used to enrich bacteria. Enterococci was identified through time-of-flight mass spectrometry. …”
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60724
Investigating slope stability of multiple stopes prone to instability in the Ziluoyi iron ore mining site
Published 2025-01-01“…By employing an appropriate rock mass reduction model, its constants (m and s) and RMR score for the consisting layers (schist layer and ore body) of the three understudy slopes (Slope#1–Slope#3) are evaluated. …”
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60725
Risk factors for symptom recurrence after microwave ablation of adenomyosis: a preliminary retrospective study
Published 2024-12-01“…Independent risk factors for symptom recurrence after MWA of adenomyosis were explored through Cox regression analysis. Kaplan-Meier (K-M) curves were plotted to estimate recurrence-free survival, and differences between groups were analyzed using the Log-Rank test.Result In total, 38 patients with adenomyosis were included, with a median follow-up duration of 15 months (interquartile range: 10-23 months). …”
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60726
Micro-jet formation induced by the interaction of a spherical and toroidal cavitation bubble
Published 2025-01-01“…The velocity of micro-jets is determined by the initial standoff distance of the spherical bubble from the wall and thus from the toroidal bubble, with peak jet velocities approaching 1000m/s. The micro-jets are triggered by the complex interaction between the torus shock wave and the surface of the spherical bubble. …”
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60727
Influence of light intensity, pre-harvest fasting, and storage time on biochemical components in serum and plasma of broilers
Published 2025-02-01“…At 42 days old, 140 broilers (3,123 ± 654 g) were assigned to two light intensities (5 or 20 lux m−2) and seven fasting times (0, 2, 4, 6, 8, 10, and 12 h). …”
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60728
miR-16-5p aggravates sepsis-associated acute kidney injury by inducing apoptosis
Published 2024-12-01“…In vitro, the expression level of miR-16-5p in HK-2 cells treated with 10 μg/mL lipopolysaccharide (LPS) increased by more than 2 times. …”
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60729
The corrosion behavior and passive film structure of industrial pure titanium with different Fe content in hydrochloric acid
Published 2025-03-01“…In this paper, the corrosion behavior and passive film structure of three Ti-xFe (x = 0.2, 0.5, 1.0 wt%) materials in 1 M hydrochloric acid were studied. The results revealed that the microstructures of Ti-xFe hot rolled plates were large lamellars α-Ti and fine lamellars β-Ti, and Fe was mainly enriched in β-Ti. …”
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60730
Feasibility and Safety of the Distal Transradial Artery for Coronary Diagnostic or Interventional Catheterization
Published 2020-01-01“…A lower body mass index was a higher risk factor for dTRA access failure (odds ratio = 0.79, P=0.024), with a cutoff of 22.04 kg/m2. Conclusion. Compared to conventional TRA, dTRA had a comparable high success rate, with fewer associated complications. …”
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60731
Molecular mapping of the grain iron and zinc concentration, protein content and thousand kernel weight in wheat (Triticum aestivum L.).
Published 2017-01-01“…A genetic map spanning 2155.3cM was constructed using microsatellite markers covering the 21 chromosomes and used for QTL analysis. 16 quantitative trait loci (QTL) were identified in this study. …”
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60732
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60733
PNPO‐Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β‐Catenin Pathway
Published 2025-02-01“…Mechanistically, PNPO oxidizes disheveled 3M282 (DVL3), leading to abnormal activation of the Wnt/β‐catenin pathway. …”
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60734
HLA-DMB correlates with antitumor immunity and an improved prognosis in endometrial carcinoma tumors
Published 2025-01-01“…Finally, the expression of HLA-DMB was validated by qPCR and immunohistochemistry.ResultsThe expression of HLA-DMB at both mRNA and protein levels is significantly higher in UCEC tissues compared to normal tissues. …”
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60735
昆明滇池红嘴鸥源沙门氏菌的分离鉴定、耐药性及致病性分析
Published 2022-01-01“…动物试验结果表明,该分离菌株对试验小鼠有一定致病性,接种浓度为5×10<sup>6</sup>、5×10<sup>7</sup>、5×10<sup>8</sup> cfu/mL的小鼠死亡率分别为60%、100%和100%,死亡小鼠出现肝脏肿大、肺部局部充血和肠壁变薄等病变。…”
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60736
Characterization of Active Compounds of Different Garlic (Allium sativum L.) Cultivars
Published 2018-03-01“…The lowest IC50 values for DPPH•, ABTS•+ scavenging and Cu2+ chelating ability were determined in Chinese garlic extracts (4.63, 0.43 and 14.90 μg/mL, respectively). Extracts from Spanish cultivar Morado and Chinese garlic were highly cytotoxic to human skin fibroblasts as they reduced cellular proliferation by 70–90%. …”
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60737
Effects of apple cider vinegar on glycemic control and insulin sensitivity in patients with type 2 diabetes: A GRADE-assessed systematic review and dose–response meta-analysis of c...
Published 2025-01-01“…We observed linear and non-linear associations between ACV consumption and FBS levels (p < 0.001). Each 1 mL/day increase in ACV consumption was associated with a-1.255 mg/dL reduction in FBS. …”
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60738
GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147
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60739
Abnormal Obesity Phenotype Is Associated with Reduced eGFR among Diabetes Mellitus and Hypertensive Patients in a Peri-Urban Community in Ghana
Published 2022-01-01“…The estimated glomerular filtration rate (eGFR) was calculated using the CKD-EPI equation, and reduced eGFR was defined as eGFR <90 ml/min/1.73 m2. Results. The prevalence of metabolically healthy nonobese (MHNO), metabolically healthy obese (MHO), metabolically abnormal nonobese (MANO), and metabolically abnormal obese (MAO) phenotypes among the study participants was 30.65%, 4.50%, 52.90%, and 11.94%, respectively. …”
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60740
Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview
Published 2025-02-01“…Novel treatments, including monoclonal antibodies (mAb), antisense oligonucleotides (ASO), and PCSK9- inhibitors nowadays, are used with greater frequency and better results, providing higher efficiency in achieving targets. …”
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