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60681
Association between Circulating B-Type Natriuretic Peptide and Diabetic Peripheral Neuropathy: A Cross-Sectional Study of a Chinese Type 2 Diabetic Population
Published 2020-01-01“…Last but most importantly, the analysis of receiver operating characteristic curves revealed that the best cutoff value for circulating levels of BNP to predict DPN was 15.18 pg/mL (sensitivity 78.7% and specificity 48.2%). These findings suggest that high circulating physiological levels of BNP may be associated with the development of DPN and may be a potential biomarker for DPN in patients with T2DM.…”
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60682
Lnc-1708对体外人骨髓间充质干细胞成骨分化的抑制效应
Published 2019-01-01“…分别转染lncRNA-1708过表达慢病毒及lncRNA-1708干扰质粒,获得稳定的hBMSC细胞株后成骨诱导分化14d,用qRT-PCR检测Runt相关转录因子2(RUNX2)、碱性磷酸酶(ALP)mRNA的表达并行碱性磷酸酶染色。【结果】相较成骨诱导分化前,3组hBMSC成骨诱导分化7d后lncRNA-1708表达量均降低(P<0.001)。…”
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60683
CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells
Published 2025-02-01“…Results The activated HER2/PI3K/AKT/mTOR signaling pathway positively correlated with SCD-1 and CD36 expression in PTEN-loss breast cancer cells. …”
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60684
Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications
Published 2021-01-01“…Considering the viability percent of cells in the PR/GO/Fe3O4 compound and comparing it with GO/Fe3O4, it can be understood that the toxic effects of polyrhodanine can diminish the metabolic activity of cells at higher concentrations (mostly more than 50 µg/mL), and PR/Fe3O4/Ko exhibited some promotive effects on cell growth, which enhanced the viability percent to more than 100%. …”
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60685
Inseguridad alimentaria en adultos yoreme-mayo del noroeste de México
Published 2024-07-01“…Las actividades con salario fueron la ocupación de dominio (f = 151; 71.2%) y el 82.1 % (f = 174) percibían menos de 6.000 pesos M.N. mensuales. Así mismo, la prevalencia general de inseguridad alimentaria fue del 89.2% (f =189) donde los grupos más afectados fueron las mujeres (f = 87, 51.8%), personas de 18 a 29 años (f = 67, 31.6%) e individuos con IMC elevado (f = 120, 56.6%). …”
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60686
Grouting Mechanism in Water-Bearing Fractured Rock Based on Two-Phase Flow
Published 2021-01-01“…When the single-hole grouting was carried out, the predetermined value can be achieved in the height range, but it was only about 15 m on the side because of the water flowing, which cannot meet the requirements. …”
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60687
The accumulation of harmful genes within the ROH hotspot regions of the Tibetan sheep genome does not lead to genetic load
Published 2025-01-01“…Results High-throughput re-sequencing technology was utilized to investigate the ROH hotspot regions across 11 Tibetan sheep populations, resulting in the identification of ten conserved genes (ARHGEF16, Tom1l2, PRDM16, PEMT, SREBF1, Rasd1, Nt5m, MED9, FLCN, RAI1) that are associated with lipid metabolism, lactation, and development. …”
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60688
RCE-IFE: recursive cluster elimination with intra-cluster feature elimination
Published 2025-02-01“…The comparability of RCE-IFE is also verified with other biological domain knowledge-based Grouping-Scoring-Modeling (G-S-M) tools, including mirGediNET, 3Mint, and miRcorrNet. …”
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60689
The use of kinematic photogrammetry and LiDAR for reconstruction of a unique object with extreme topography: a case study of Dutchman’s Cap, Baltic seacoast, Lithuania
Published 2025-02-01“…The evaluation of aerial mapping products showed that the best accuracy was achieved with products derived from the combined image sets, based on the metric of RMSE, with a mean RMSE of 0.048 m in X, Y, and Z directions. The spatial model generated from LiDAR data is more accurate in Z direction. …”
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60690
Vitamin D Regulates the Expression of Glucocorticoid Receptors in Blood of Severe Asthmatic Patients
Published 2021-01-01“…Upon VitD supplementation of severe asthmatic patients, there was a significant increase in the blood levels of GR-α with no change in GR-β mRNA expression. VitD supplementation also suppressed the blood levels of IL-17F and IL-4. …”
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60691
Process Optimization and Flavor Substance Analysis of Probiotic Fermented Apple Juice
Published 2025-01-01“…Under these conditions, the fermented apple juice exhibited a viable cell count of 7.2×108 CFU/mL and received a sensory score of 92.13 points. …”
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60692
Office BP measurement using conical cuffs in children and adolescents with obesity
Published 2024-12-01“…Arm circumference AC was measured in all participants, and the appropriate cuff size was selected for both conical and cylindrical cuffs.Results Mean participants’ age was 11.8[Formula: see text]2.5 years, mean BMI was 28.8[Formula: see text]3.4 kg/m2, mean BMI z-score was 2.12[Formula: see text]0.32, and mean AC was 30.0[Formula: see text]3.6 cm. …”
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60693
多西紫杉醇联合二烯丙三硫协同诱导前列腺癌细胞凋亡的研究
Published 2012-01-01“…【结果】 多西紫杉醇、DATS均能抑制PC-3细胞的生长,DATS可明显提高多西紫杉醇的杀伤效应,DATS(15 μmol/L)联合多西紫杉醇(10 nmol/L)作用48 h的细胞生存率为(50.1±1.0)%,低于多西紫杉醇(67.4±1.0)%和DATS(69.2±1.8)%,二者具有协同抑瘤作用;联合组使细胞凋亡率及G2/M期细胞比率明显增高,并更能显著抑制Bcl-2、Bcl-xL的表达,而且联合组使细胞色素C的释放及caspase-9、caspase-3的裂解活化时间提前了8 h。…”
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60694
Accelerated TLPD bonding of reliable IMCs micro joints using Cu–8Ni substrate under thermal gradient: Experiments and theoretical calculations
Published 2025-03-01“…In this study, a novel TLPD bonding method under thermal gradient (TG) with Cu–8Ni alloy as the substrate on the one side of Cu/Sn(40 μm)/Cu–8Ni micro joints was designed. Additionally, the microstructure, elemental characteristics, grain features and shear strengths of the bonded and aged micro joints were systematically investigated. …”
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60695
Tailoring Borate Mediator Species Enables Industrial CO Production with Improved Overall Energy Efficiency by Sustainable Molten Salt CO2 Electrolysis
Published 2025-01-01“…Cathodic CO2 electro‐reduction (CO2ER) with the anodic oxygen evolution reaction (OER) at an overall current density of 500 mA cm−2 using non‐nanostructured transition‐metal plate electrodes at 650 °C is coupled. …”
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60696
Perbandingan pembuatan produk menggunakan simulasi program CNC dan CNC Milling
Published 2022-04-01“…Kesalahan pembuatan program dan pemosisian sumbu X, Y dan Z dapat dapat diminimalkan dengan melakukan simulasi pengerjaan benda kerja tersebut seperti pemasukan kode-kode pemotongan benda kerja pada mesin CNC Milling (kode G dan M). Program simulasi yang dapat digunakan adalah <em>Mastercam</em>, swansoft simulation CNC (SSNC) dan lainnya. …”
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60697
Occupational adjustments and work ability of young adult cancer survivors: results from the AYA-Leipzig study
Published 2024-12-01“…Results Out of 438 AYA-CS, 389 (88.8%) returned to work after cancer diagnosis and were included in analyses. Mean work ability was M = 36.2 (SD = 6.9), 11.4% reported poor, 34.7% moderate, 41.4% good and 12.5% excellent work ability. …”
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60698
Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial
Published 2025-01-01“…This study evaluated the efficacy of the nasal-spraying probiotics (LiveSpo Navax containing 5 billion Bacillus subtilis and B. clausii spores/5 mL) as a supportive treatment for dual ARS and AOM with otorrhea in a randomized, single-blind, controlled clinical trial. …”
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60699
Do Self-Expanding Metal Stents as a Bridge to Surgery Benefit All Patients with Obstructive Left-Side Colorectal Cancers?
Published 2019-01-01“…The 3-year OS rate was influenced by the cM stage (p=0.003). Patients with non-pT4 stages in the SEMS group showed obviously better 3-year OS (95.0%) than the other subgroups. …”
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60700
Osmanlı’dan Cumhuriyet’e İstanbul’da Esrar Tekkeleri
Published 2024-06-01“…İnsanlığın ilk dönemlerinden itibaren bilinen bitki, ilaç yapımında kullanılmış ve çoğu hastalığa iyi geldiği hem batılı hem de Müslüman hekimler tarafından ifade edilmiştir. Esrarın Avrupa’ya M.Ö. 7. yüzyılda İskitler ya da Mısırlılar aracılığıyla taşındığı sanılmaktadır. …”
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