Inhibition of Endothelial Cell Tube Formation by Anti-Vascular Endothelial Growth Factor/Anti-Angiopoietin-2 RNA Nanoparticles by Cheng Zhong, Zhanquan Shi, Chia-Yang Liu, Daniel W. Binzel, Kai Jin, Xin Li, Peixuan Guo, S. Kevin Li

“…<b>Results</b>: The results demonstrated the inhibition effects of the RNA nanoparticles on endothelial cell tube formation at 67 nM in a 3D spheroid sprouting model. The results in the 3D spheroid sprouting assay are consistent with those of the WST-1 proliferation assays. …”
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Outburst mechanism and hazard prevention technique of limestone aquifer under isolated island panels by Wei Wang, Wei Wang, Wei Wang, Yanjun Wu, Yanjun Wu, Yanjun Wu, Yongli Shi, Yongli Shi, Yongli Shi, Jingzhong Zhu

“…The study results indicate that (1) the depth of the floor failure zone is 27.51 m and that the risk owing to water inrush of the panel floor in the isolated islands exists. …”
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Development of a Cell-Based High-Throughput Screening Assay to Identify Porcine Host Defense Peptide-Inducing Compounds by Zhuo Deng, Jing Wang, Wentao Lyu, Xuwen Wieneke, Robert Matts, Xi Ma, Guolong Zhang

“…Eight compounds were subsequently observed to be comparable to sodium butyrate in inducing PBD3 mRNA expression in parental IPEC-J2 cells in the low micromolar range. …”
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Profiling of Indigenous Biosurfactant-Producing Bacillus Isolates in the Bioremediation of Soil Contaminated by Petroleum Products and Olive Oil by Paola Sandra Elenga-Wilson, Christian Aimé Kayath, Nicaise Saturnin Mokemiabeka, Stech Anomene Eckzechel Nzaou, Etienne Nguimbi, Gabriel Ahombo

“…Biosurfactant secreted by Bacillus strains has shown an antagonistic effect in Escherichia coli, Shigella flexneri 5a M90T, and Bacillus cereus. The selected isolates could therefore be safely used for biodegradation. …”
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Anticancer activity of Ilex khasiana, a rare and endemic species of holly in Northeast India, against murine lymphoma by Charles Lalnunfela, Pawi Bawitlung Lalthanpuii, Hmar Tlawmte Lalremsanga, Zothansiama, Chhaihlo Lalmuansangi, Mary Zosangzuali, Nachimuthu Senthil Kumar, Tochhawng Lalhriatpuii, Kholhring Lalchhandama

“…Alkaline comet assay showed that the plant extract effectively induced DNA damage, producing a tail length of 11.89 μm and Olive moment of 2.36 at 250 mg/kg bwt, the most effective dosage. …”
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Neuregulin1 ameliorates metabolic dysfunction-associated fatty liver disease via the ERK/SIRT1 signaling pathways by Chengan Xu, Shouhao Wang, Di Meng, Mingshan Wang, Rong Yan, Yining Dai

“…HepG2 cells induced by oleic acid and palmitic acid were treated with 20ng/mL NRG1 and 10µmol/L PD98059. The changes of histopathological, biochemical indexes, inflammatory factors, lipid metabolism, apoptosis and autophagy parameters were measured. …”
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β-crystals aied greater energy absorbing ethylene–propylene rubber in polypropylene blends for outstanding low-temperature toughness by Ruimiao Liang, Wenwen Yu, Jiahao Shen, Zhiyi Zhang, Zaifu Lin, Jiayi Wang, Lan Jia, Feng Chen, Yonggang Shangguan, Qiang Zheng

“…Under an extreme low-temperature condition of −40 °C, the PP/EPR/TMB-5 blends exhibit a remarkable enhancement in low-temperature toughness compared with PP/EPR blends, showing a 138 % increase to reach 38.3 kJ/m2. In addition, these blends demonstrate an 8.47 % increase in tensile strength at room temperature. …”
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Comparative Analysis of Adverse Drug Reactions Associated with Fluoroquinolones and Other Antibiotics: A Retrospective Pharmacovigilance Study by Alshareef H, Alenzi KA, Albalawi BR, Alanazi RM, Albalawi NS, Alasoufi WS, Alqifari S, Ahmed R, Ali MAS

“…Hanan Alshareef,1 Khalidah A Alenzi,2 Budor R Albalawi,3 Rinas M Alanazi,3 Nawal S Albalawi,3 Wedad Saleem Alasoufi,3 Saleh Alqifari,1 Rehab Ahmed,4 Mostafa AS Ali1 1Pharmacy Practice Department, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia; 2Transformation and Business Development, Tabuk Health Cluster, Tabuk, Saudi Arabia; 3Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia; 4Division of Microbiology, Immunology and Biotechnology, Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi ArabiaCorrespondence: Hanan Alshareef, Pharmacy Practice Department, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia, Email halsharef@ut.edu.saBackground: Fluoroquinolones (FQs) are among the most popular antimicrobials that are highly effective against various infections. …”
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Exploration of the Immune-Related Signatures and Immune Infiltration Analysis in Melanoma by Ai-lan Li, Yong-mei Zhu, Lai-qiang Gao, Shu-yue Wei, Ming-tao Wang, Qiang Ma, You-you Zheng, Jian-hua Li, Qing-feng Wang

“…The Wilcoxon rank-sum test was used to estimate immune infiltration density in the two groups, and results showed that the high-risk group exhibited a lower infiltration density, and the dominant immune cells included M0 macrophages (P=0.023) and activated mast cells (P=0.005).…”
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Analisis Kesalahan Mahasiswa dalam Pembuktian Identitas Trigonometri by Ucik Fitri Handayani, Wildan Hakim, Anggita Oktaviana Putri

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各期慢性阻塞性肺疾病患者诱导痰细胞成分与肺功能的关系 by 曾勉, 刘凌云, 张式鸿, 谢灿茂, 王辉, 黄晓梅

“…A，组、A2组、B组、C组诱导痰中细胞总数（106／mL）分别为（8．8±3．7）、（6．5±2．6）、（5．0±2．8）、（2．8±1．3），细胞分类中A。…”
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The Association of Thyroid Hormone Changes with Inflammatory Status and Prognosis in COVID-19 by Ceyda Dincer Yazan, Can Ilgin, Onur Elbasan, Tugce Apaydin, Saida Dashdamirova, Tayfun Yigit, Uluhan Sili, Aysegul Karahasan Yagci, Onder Sirikci, Goncagul Haklar, Hulya Gozu

“…In cluster analysis, a high-risk group with a lower median FT3 value (median = 2.34 ng/L; IQR = 0.86), a higher median FT4 value (median = 1.04 ng/dL; IQR = 0.33), and a lower median TSH value (median = 0.62 mIU/L; IQR = 0.59) included 8 of 9 died patients and 25 of the 31 patients that were admitted to ICU. …”
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Incidence of alexithymia in worsening symptoms and quality of life of Systemic Lupus Erythematosus patients (SLE) by Fabio Rapisarda, Concetta Mezzatesta, Antonina Butticè, Alessandro Raffa, Stefano Boca

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The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study by Zou Y, Yang Y, Yang J, Zhang Y, Zhao C, Qin L, Hu N

“…At a cut-off of 10.305 pg/mL, SF IL-10 had an area under the ROC curve (AUC) of 0.891, with 92.16% sensitivity and 77.91% specificity. …”
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Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors by Romain Pacaud, Scott Thomas, Sibapriya Chaudhuri, Ann Lazar, Luika A. Timmerman, Pamela N. Munster

“…Results Our targeted variants and cells with intrinsic BRCA1/2 mutations responded to low dose combination therapeutic treatment by G2M stalling, compounded DNA damage, severely attenuated colony formation, and importantly, increased cell death. …”
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Amorphization and siliconization of silicon carbide as a first wall material by Aritra De, Jerome Guterl, Zachary Bergstrom, Tyler Abrams, Gregory Sinclair, John David Elder, Dmitry Rudakov

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Eğitim Çalışanlarının Yansıtıcı Düşünme Becerilerinin Çeşitli Değişkenler Açısından İncelemesi-Examination Of Reflective Thinking Styles Of Education Emloyees In Terms Of Some Vari... by Gizem Saygılı, Songül Tehneldere

“…&Ouml;ng&ouml;r&uuml;l&uuml; ve i&ccedil;ten olma ile mesleğe bakış alt boyutlarının haricindeki t&uuml;m alt boyutlarda katılımcıların mesleki kıdemlerine g&ouml;re anlamlı farklılık bulunmaktadır (p&lt;0,05). …”
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Excitation of ULF, ELF, and VLF Resonator and Waveguide Oscillations in the Earth–Atmosphere–Ionosphere System by Lightning Current Sources Connected with Hunga Tonga Volcano Erupt... by Yuriy G. Rapoport, Volodymyr V. Grimalsky, Andrzej Krankowski, Asen Grytsai, Sergei S. Petrishchevskii, Leszek Błaszkiewicz, Chieh-Hung Chen

“…The density of effective lightning current in the ULF range reaches the value of the order of 10⁻⁷ A/m². A combined dynamic/quasi-stationary method has been developed to simulate ULF penetration through the lithosphere (Earth)–atmosphere–ionosphere–magnetosphere system. …”
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Impact of centrifugal therapeutic plasma exchange on platelet counts in patients with neurological autoimmune diseases by GAO Qingmei, ZHU Xinfang, WANG Yuan, ZHONG Yao, ZHANG Qi, XIA Rong

“…[Results] The duration of a single TPE in this study was 94(84,107) minutes, and the actual volume of a single TPE replacement was 2 456(2 142, 2 785) mL. The number of patients who underwent TPE for 2, 3, 4, and 5 sessions was 17, 28, 18, and 126, respectively. …”
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Metabolite profile and antioxidant activities of Trikatu, black pepper, Javanese long pepper, and red ginger essential oils by Dewa Ayu Ika Pramitha, Tati Herlina, Iman Permana Maksum, Ari Hardianto, Abd. Wahid Rizaldi Akili, Jalifah Latip

“…The antioxidant activities of TR, BP, JLP, and RG essential oils were significantly different, with RG showing the lowest IC50 value 2.73 ± 0.09 mg/mL, indicating higher antioxidant potential compared to BP and JLP. …”
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