DEVICE FOR CALIBRATION OF THE PRESSURE SENSOR OF GRANULAR BULK MATERIALS by A. Zhdanov, V. Petrov, Y. Misko

“…In order to exclude the impact on the measured pressure by arching in the loose material above the sensor platform, linear displacements of the sensor platform relative to the housing should not exceed 5-8 ?m. Such small movements are measured by a non-contact pneumatic gauge based on a non-differential measuring pneumatic system of the manometric type with a working air pressure in the system of 7.5-10 kPa. …”
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Negative perceptions toward older adults and life satisfaction among community-dwelling older citizens in Japan [version 2; peer review: 1 approved, 2 approved with reservations] by Yuho Shimizu, Hiroyuki Suzuki, Tomoki Furuya, Ai Iizuka, Keigo Hinakura, Tomoya Takahashi, Yan Li, Daichi Yamashiro, Yoshifumi Takahashi, Daisuke Cho, Susumu Ogawa, Kenichiro Sato

“…Data from 285 participants (264 women, M = 71.97 years) were analyzed. Results The intraclass correlation coefficient for life satisfaction concerning residential areas was. 03 (95% confidence interval [CI] = [-.03, .10]). …”
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The Association between Short-Term PM2.5 Exposure and Long COVID on the Respiratory System by Pornpun Sakunkoo, Chananya Jirapornkul, Naowarat Maneenin, Yuparat Limmongkon, Jetnapis Rayubkul, Kittipong Sornlorm, Rajitra Nawawonganun

“…It was found that the prevalence of Long COVID on the respiratory system: participants exposed to PM2.5 at 26–37 µg m−3. had an increased risk of developing Long COVID on the respiratory system at 50.54% (95% CI: 40.20–60.84), exposure to PM2.5 ≥ 1 hour per day (AOR = 1.84, 95% CI: 1.33–2.55, lived in urban areas (AOR: 1.64, 95% CI: 1.13–2.37), not wore a face mask to prevent PM2.5 exposure (AOR: 1.78, 95% CI: 1.25–2.54), female (AOR: 1.51, 95% CI: 1.05–2.18), farmer (AOR: 5.78, 95% CI: 1.05–2.18). …”
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Conducting clinical trials with self-collection of pharmacokinetic samples: Experience from an exploratory, phase 1, open-label trial of centanafadine SR in healthy individuals by Chelsea Ye, Tatiana Shablinski, Susan E. Shoaf, Chris Chung, Michelle Bullock

“…Methods: Healthy adults (18–55 years) with a body mass index of 19.0–32.0 kg/m2 were enrolled. The trial comprised a screening period, 2 clinic visits (visits 1, 2), 2 at-home visits (visits 3 and 4), and follow-up clinic visit (visit 5). …”
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Effects of Fasudil on Patients with Pulmonary Hypertension Associated with Left Ventricular Heart Failure with Preserved Ejection Fraction: A Prospective Intervention Study by Xiang Zhang, Xueming Zhang, Saihua Wang, Jun Luo, Zhihong Zhao, Changzhu Zheng, Jieyan Shen

“…Besides, the RPH group demonstrated a greater transpulmonary pressure gradient (TPG) and pulmonary vascular resistance (PVR) than the PPH group (p<0.01 for both) as well as pulmonary arterial systolic pressure (PASP) and mean pulmonary arterial pressure (mPAP) (p<0.01 for both), which fits the feature of RPH. …”
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Potencial prebiótico in vitro del extracto atomizado de Swartzia polyphylla, Maytenus macrocarpa y Jatropha macrantha sobre Lactobacillus plantarum y Lactobacillus acidophilus by DELIA ROSA PARIONA HUAPAYA, Amparo Iris Zavaleta, GINA FIORELLA ACUÑA RAMIREZ, KARIN LUCIA ZAMUDIO MALPARTIDA

“…El EA estimuló el crecimiento bacteriano manteniendo una concentración celular mayor a 10 x 106 UFC/mL durante 48 h. Las velocidades de crecimiento fueron 0,635 y 0,656 h-1 para L. plantarum; así como, 0,391 y 0,516 h-1 para L. acidophilus en los medios EA 1% y 2% respectivamente. …”
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A gene expression atlas of Nicotiana tabacum across various tissues at transcript resolution by Shizhou Yu, Jufen Wan, Jufen Wan, Tenghang Xu, Tenghang Xu, Jie Zhang, Linggai Cao, Jie Liu, Hongfeng Liu, Xueliang Ren, Zhixiao Yang

“…Alternative splicing (AS) expands the transcriptome diversity by selectively splicing exons and introns from pre-mRNAs to generate different protein isoforms. This mechanism is widespread in eukaryotes and plays a crucial role in development, environmental adaptation, and stress resistance. …”
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B Cell Activation, Differentiation, and Their Potential Molecular Mechanisms in Osteoarthritic Synovial Tissue by Lu P, Li Y, Yang S, Yao H, Tu B, Ning R

“…Specifically, the proportion of activated CD86+ B cells and the differentiation marker HLA-DR+ increased with disease severity, whereas the proportion of the differentiation marker IgM decreased. The proportion of CD38+ B cells also decreased with increasing severity, although this change lacked statistical significance. …”
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Comprehensive analysis of histophysiology, transcriptomics and metabolomics in goslings exposed to gossypol acetate: unraveling hepatotoxic mechanisms by Jun Yu, Jun Yu, Haiming Yang, Jian Wang, Zixin Huang, Shi Chen, Hongchang Zhao, Jun Wang, Zhiyue Wang

“…Forty-eight 7-day-old male goslings with similar body weight (BW) were randomly assigned to two groups: a control group, receiving a saline solution (0.9%, 2.5 mL/kg BW), and a GA-treated group, administered GA at 50 mg/kg BW orally for 14 days. …”
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B细胞淋巴瘤SHP-1基因甲基化状态及其意义 by 汪清铭, 吴祥元, 王东宁, 林曲, 董敏, 温景芸

“…【方法】收集存档石蜡包埋组织标本61例(52例B细胞非霍奇金淋巴瘤标本,9例良性增生淋巴结标本),健康人外周血单个核细胞DNA标本15例,用甲基化特异性PCR(methylation-specific PCR,MSP)和非甲基化特异性PCR(unmethylation-specific PCR,un-MSP)检测SHP-1启动子区域CpG岛甲基化状态,MSP、un-MSP和RT-PCR方法分别检测接受或未接受去甲基化处理的Burkitt淋巴瘤细胞系Raji的甲基化状态及mRNA的表达,MTT法检测接受去甲基化干预后细胞生长受抑情况。【结果】SHP-1基因启动子区域在弥漫性大B细胞淋巴瘤和滤泡性淋巴瘤甲基化频率分别为94%及97%,对照组9例淋巴结良性增生标本和15例正常人外周血单个核细胞标本中SHP-1基因启动子区域甲基化频率为0。…”
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贵州丽松鼠亚科动物资源调查 by 蔡延芳 张海波 胡灿实 陈 果 粟海军

“…(3)随海拔的上升丽松鼠的分布逐渐减少,4种丽松鼠主要集中分布在900～1500 m之间海拔地带。(4)赤腹松鼠多活动在以马尾松、杉木等为主的针叶林和针阔混交林,红腿长吻松鼠活动在具开阔林窗的阔叶林带,珀氏长吻松鼠则经常出没在农耕地附近和灌丛中,阔叶林、针阔混交林则是隐纹花松鼠最常利用的生境。…”
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The Role of Microelements of Lumbar Disc Degeneration in Patients Undergoing Lumbar Spine Surgery by Sadiq R. Karkush, Manal K. Rasheed, Ali T. Abdul Wahid, Ahmed R. Majeed

“…The body mass index (BMI) was determined using the formula: BMIg/m2 = weight/height2. Results: The patients had a lower mean zinc level (57.3 ± 14.56 Mmol/L) and a higher mean copper level (106.6 ± 39.41 Mmol/L) in comparison to healthy controls (96.4 ± 17.38 Mmol/L) and (61.0 ± 9.53 Mmol/L), respectively There was a weak relationship and a significant correlation between copper and zinc (r = -0.2). …”
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Proactive Maintenance and Data-Driven Optimization of Mineral Lubricating Oil in a Gas Engine Cogeneration System Extending Oil Change Intervals for Cost Savings and a Reduced Envi... by Krzysztof Pytel, Roman Filipek, Adam Kalwar, Małgorzata Piaskowska-Silarska, Wiktor Hudy, Jana Depešová, Franciszek Kurdziel

“…., while avoidable waste generation reached 18.2 m³ of mineral oil. Regular oil analysis conducted every 1000 operating hours proved critical for early detection of oil degradation, supporting proactive maintenance strategies and ensuring optimal engine performance and longevity.…”
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Soil Degradation Evidence Following a Wildfire in Arequipa’s Andean Region, Peru by Lunsden Coaguila, Jorge Mataix-Solera, Sonia Nina, Minerva García-Carmona, Elizabeth T. Salazar

“…The study investigates the effects of a 2018 wildfire in the Pichu Pichu volcano mountain area, a shrubland ecosystem at 3,700 m a.s.l. The arid conditions and unique soil characteristics, such as the Torripsamment soil on volcaniclastic sandstones, make the area particularly vulnerable to fire-induced degradation. …”
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Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes by Yukiko Kikuchi, Mohammed Uddin, Joris A. Veltman, Sara Wells, Christopher Morris, Marc Woodbury-Smith

“…Methods We used the macaque Genotype and Phenotype (mGAP) resource consisting of 2,054 macaque genomes to examine patterns of evolutionary constraint in known human neurodevelopmental genes. …”
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The transcriptome of MHV‐infected RAW264.7 cells offers an alternative model for macrophage innate immunity research by Yun Liu, Ting‐Ting Feng, Wei Tong, Zhi Guo, Xia Li, Qi Kong, Zhi‐Guang Xiang

“…Results The transcriptome analysis showed the immediate (3 hpi.) up regulation of DEGs related to inflammation, like Il1b and Il6. DEGs related to M2 differential polarization, like Irf4 showed up regulation at 24 hpi., the late term after viral infection. …”
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Endometrial factors in the implantation failure spectrum: protocol of a MUltidisciplinary observational cohort study in women with Repeated Implantation failure and recurrent Misca... by Servaas Morré, Ron van Golde, Andrea Romano, Linda Stevens Brentjens, Denise Habets, Janneke Den Hartog, Salwan Al-Nasiry, Lotte Wieten, Aafke Van Montfoort

“…The study parameters are the steroid profile (steroid levels and mRNA levels, protein expression and activity of steroid enzymes) in endometrial tissue and peripheral blood, as well as the activating or inhibitory phenotype of uNK cells based on receptor expression in menstrual blood and endometrial tissue and determination of the vaginal and endometrial microbiome using the inter spacer bacterial profiling technique.Ethics and dissemination The protocol is approved by the local medical ethical review committee at the Maastricht University Medical Centre. …”
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硫唑嘌呤治疗系统性红斑狼疮的不良反应与硫嘌呤甲基转移酶活性的关系

“…血液系统损害主要表现为白细胞减少（20例，8.0%），血小板减少（9例，3.6%）。所有患者的TPMT活性（按RBC，U/mL）均值为12.4±7.1（1.7-30.0）,呈正偏态连续分布。出现血液系统损害、脱发的患者TPMT活性明显低于未发生的患者（P<0.001）。…”
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Analysis of the Clinicopathological Characteristics, Genetic Phenotypes, and Prognostics of Primary Pulmonary and Bronchial Adenoid Cystic Carcinoma by Zhengyang Hu, Xing Jin, Jian Wang, Qihai Sui, Yanjun Yi, Dejun Zeng, Zhencong Chen, Qun Wang, Jiacheng Yin, Lin Wang, Zongwu Lin

“…Race, pathological grade, M stage, regional node examination, and regional node positive were independent prognostic factors for the OS of patients who underwent surgery. …”
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A Body‐Temperature‐Triggered In Situ Softening Peripheral Nerve Electrode for Chronic Robust Neuromodulation by Xueyang Ren, Wenjie Tang, Yuehui Yuan, Shisheng Chen, Fangzhou Lu, Jinyang Mao, Jidan Fan, Xufeng Wei, Ming Chu, Benhui Hu

“…Furthermore, the decreased interfacial impedance (325.1 ± 46.9 Ω at 1 kHz) and increased charge storage capacity (111.2 ± 5.8 mC cm−2) are achieved by an in situ electrografted conductive polymer on the strain‐insensitive conductive network of Au nanotubes. …”
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