Exosomal miR-21-5p from glioma associated mesenchymal stem cells promotes the progression and glycolysis of glioblastoma via PDHA1 by Yanbin Zhang, Peng Lv, Qing Zhang, Wei Xiang, Xiaobing Jiang, Zijun Guo, Tao Zhang

“…Mechanismly, miR-21-5p directly binds to the mRNA of PDHA1 and downregulates its transcription, thereby promoting GBM glycolysis. …”
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Efficient and Rapid Microfluidics Production of Bio-Inspired Nanoparticles Derived from <i>Bombyx mori</i> Silkworm for Enhanced Breast Cancer Treatment by Muhamad Hawari Mansor, Zijian Gao, Faith Howard, Jordan MacInnes, Xiubo Zhao, Munitta Muthana

“…In vitro studies demonstrated sustained cytotoxic effects, and cell cycle arrest at the G2/M phase in breast cancer cell lines, with minimal toxicity in non-cancerous cells. …”
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Optimizing Operating Room Efficiency for Primary Hip and Knee Arthroplasty Using Performance Benchmarks by Koorosh Kashanian, BMSc, Matey Juric, BSc, Tim Ramsay, PhD, Pascal Fallavollita, PhD, Paul E. Beaulé, MD, FAAOS, FRCSC

“…All surgeries were performed as outpatients and included 160 females and 135 males; 161 TKA and 134 THA; mean age, 66.1; mean body mass index, 28.6 kg/m2; American Society of Anesthesia, 2. Time points, demographics, and adverse events were recorded. …”
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Screening chimique, activités antioxydante et antiplasmodiale des extraits d’écorces de tronc d’Enantia olivacea Robyns &amp; Ghesq (Annonaceae), une plante utilisée par les bonobo... by Papy Kunyima, Nseu B Mbomba, Mulavwa Habari, N Lami, Tshimankinda Mpiana, Musuyu Muganza

“…Nous avons réalisé des mesures semi-quantitatives de l’activité antioxydante par le radical 1,1-diphényl-2-picrylhydrazyle (DPPH) d’une solution méthanolique à 2 % (m/v) sur chromatographie en couche mince (CCM), et à 0,004 % une mesure quantitative sur microplaque. …”
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Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS by Weiyi Cao, Hezhi Yao, Zhenzhen Qian, Yi Wu, Shuge Wang, Rui Li, Rui Gao

“…Calibration curves in the range 5–6000 ng/mL, all with correlation coefficients greater than 0.99, were established using linear regression models for salvianolic acid B and acetylsalicylic acid and a quadratic model for salicylic acid. …”
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Enhanced wear resistance, hydrophobic properties and corrosion resistance of plasma electrolyte oxidation coatings on Ti6Al4V alloys via addition of ZrO2 nanoparticles by Yue Yang, Weihua Zhang, Kunlong Zhang, Xiangyu Sun, Boxuan Men, Sirong Yu

“…The dual-layered nanocomposite-PEO coatings consisting of anatase, rutile, TiP2O7, m-ZrO2, t-ZrO2, ZrTiO4 and Zr3(PO4)4 were formed, and ZrO2 NPs were incorporated into the coatings via both inertia and reactive modes. …”
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Bias in Discontinuous Elevational Transects for Tracking Species Range Shifts by Shixuan Li, Jiannan Yao, Yang Lin, Siyu Wu, Zhongjie Yang, Chao Jin, Yuhan Zhang, Zhen Wang, Jinliang Liu, Guochun Shen, Mingjian Yu

“…Our pioneering assessment of bias in discontinuous elevational transects demonstrates that a 50 m quadrat spacing combined with a 60-year survey interval optimizes monitoring species range shifts for conservation planning. …”
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Effects of systemic glucocorticosteroids on peripheral neutrophil functions in asthmatic subjects: an ex vivo study by P. L. Paggiaro, L. Bancalari, D. Giannessi, W. Bernini, G. Lazzerini, R. Sicari, E. Bacci, F. L. Dente, B. Vagaggini, R. De Caterina

“…After treatment, there was no significant change in all neutrophil functions, except for a decrease in neutrophil chemotaxis in subjects who showed an FEV1 increase > 20% after GCS treatment (from 131 ± 18 to 117 ± 21 μm, p = 0.005). Chemokinesis sicantly decreased in all subjects, and the changes significantly correlated with an arbitrary score of the total administered dose of GCS (r = 0.57, p < 0.05). …”
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Barriers to social participation for people with disabilities in NTD-endemic areas of Benin and Côte d'Ivoire: Assessing scope and associated factors. by Yévèdo Borel Tossou, Paule Héléna Biaka, Fifamin Noël Christelle Gbaguidi, Vignon Bedie, Sonagnon Inès Elvire Agbo, Fernand Aimé Guedou, Kouakou Jerôme Kouadio, Sèdjro Gimatal Esaï Anagonou, Franck Zinsou Mignanwande, Parfait Djossou, Brunelle Vanessa Yemadje, Flora Sylvie Houndjrebo, Jeanne d'Arc Natacha Lessanh Arrawo, Yvette Faihoun, Harvey Johnson, Ghislain Emmanuel Sopoh, Jean Gabin Houezo, Mamadou Kaloga, Agui Sylvestre Dizoe, Mark Nichter, Anna Gine-March, Roch Christian Johnson

“…The median age (Q1; Q3) was 38 (22; 52) years, and the M/F ratio was 1.45. Of the respondents, 89.2% had a monthly income between 0 and 50,000 FCFA (76 euros); 43.7% were married, and 64.4% were uneducated. …”
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Dried Apricot Polyphenols Suppress the Growth of A549 Human Lung Adenocarcinoma Cells by Inducing Apoptosis via a Mitochondrial-Dependent Pathway by Caiyun Zhao, Jingteng Wang, Jintian Guo, Wenjing Gao, Bin Li, Xin Shang, Li Zheng, Bin Wu, Yinghua Fu

“…The results indicated that dried apricot polyphenols (DAPs) could cause cell cycle arrest in the G0/G1 and G2/M phases by decreasing the cyclin D1, CDK4, cyclin B1, CDK1, and CDK6 levels in A549 human lung adenocarcinoma cells. …”
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First report on comprehensive genomic analysis of a multidrug-resistant Enterobacter asburiae isolated from diabetic foot infection from Bangladesh by Md. Rafiul Islam, Spencer Mark Mondol, Md. Azad Hossen, Mst. Poli Khatun, Shahjada Selim, Amiruzzaman, Donald James Gomes, Md. Mizanur Rahaman

“…In this study, we present the detailed analysis of the whole genome sequence of a multidrug-resistant (MDR) E. asburiae strain BDW1M3 from Bangladesh. The isolate was collected from an infected foot wound of a diabetic foot ulcer patient. …”
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A Novel Eco-Friendly Process for the Synthesis and Purification of Ascorbyl-6-Oleates by Ha-Eun Ji, Se-Young Kim, Heejin So, Vivian Prayitno, Ki-Teak Lee, Jung-Ah Shin

“…FT-IR confirmed the presence of the ester bond (1733 cm⁻¹) and olefin structure (3006 cm⁻¹) of OA, and LC-ESI-MS/MS identified AO peaks at <i>m/z</i> 439.3. DSC analysis showed broad endothermic curves at 23.1–46.7 °C when the purified AO samples were pre-cooled at −25 °C.…”
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Identification of a Ferroptosis-Related Signature Associated with Prognosis and Immune Infiltration in Adrenocortical Carcinoma by Xi Chen, Lijun Yan, Feng Jiang, Yu Lu, Ni Zeng, Shufang Yang, Xianghua Ma

“…The prognostic value of the ferroptosis risk signature was assessed using K-M and ROC curves. Furthermore, we performed GSEA to discover the enriched gene sets in high-risk group. …”
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Role of Sex Hormones in the Development and Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma by Maurizio Montella, Giovanni D’Arena, Anna Crispo, Mario Capunzo, Flavia Nocerino, Maria Grimaldi, Antonio Barbieri, Anna Maria D’Ursi, Mario Felice Tecce, Alfonso Amore, Massimiliano Galdiero, Gennaro Ciliberto, Aldo Giudice

“…Additionally, sex hormones can also affect HBV-related hepatocarcinogenesis by inducing epigenetic changes such as the regulation of mRNA levels by microRNAs (miRNAs), DNA methylation, and histone modification in liver tissue. …”
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Microstructure evolution and mechanical properties of ZK61 magnesium alloy fabricated via friction stir additive manufacturing by Yichen Xiao, Lei Shi, Chuansong Wu, Shengli Li, Ji Chen, Wenjian Ren

“…The microstructure in the additive zone of the Mg alloy component prepared by FSAM shows uniform and fine equiaxed grains with a size range of 2–6 μm. In the direction parallel to the traverse direction, a strong {0001} basal texture is formed. …”
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Treatment of a femoral neck fracture in a patient with dwarfism: a case report by Junyan Zhao, Liuliu Chen, Kun He, Muyao Li, Zhenwen Li, Hui Lin, Songjun Li

“…The patient presented with characteristic features of dwarfism, including diminutive stature (1.2 m), multiple skeletal abnormalities, and significant osteoporosis. …”
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Nailfold capillary abnormalities as indicators of diabetic nephropathy progression: a cross-sectional study in type 2 diabetes by Po-Chi Hsu, Pei-Yung Liao, Ssu-Wei Huang, Hen-Hong Chang, John Y. Chiang, Lun-Chien Lo

“…The ‘comma-like’ capillary distribution pattern (23.08%, p = 0.016), more ratio of ramified capillaries (p = 0.0137) were observed in the eGFR <30 ml/min/1.73m2 group. Reduced fundus transparency (p = 0.0015) and impaired visibility of the sub-venous plexus (p = 0.0016) were noted in the lower eGFR groups. …”
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Interleukin-10 Polymorphisms in Association with Prognosis in Patients with B-Cell Lymphoma Treated by R-CHOP by Min Kyeong Kim, Kyong-Ah Yoon, Eun Young Park, Jungnam Joo, Eun Young Lee, Hyeon-Seok Eom, Sun-Young Kong

“…Previous studies have revealed that the transcription of IL10 mRNA and its protein expression may be infl uenced by several single-nucleotide polymorphisms in the promoter and intron regions, including rs1800896, rs1800871, and rs1800872. …”
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Reductions in Muscle Strength and Range of Motion Cause Locomotion Disability via Locomotion-Related Functional Limitation in Japanese Older Adults: A Cross-Sectional Study by Hungu Jung, Shigeharu Tanaka, Yuji Iwamoto, Takashi Kawano, Masahiro Yamasaki, Ryo Tanaka

“…To measure locomotion-related functional limitations, participants underwent a 10 m hurdle walking test and side-step test. Thereafter, path analysis was conducted for testing the hypothetical model. …”
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Pheochromocytoma in Congenital Cyanotic Heart Disease by Carmen Aresta, Gianfranco Butera, Antonietta Tufano, Giorgia Grassi, Livio Luzi, Stefano Benedini

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