Historical dynamics of marginal populations at the leading edge of a temperate species in the boreal‐temperate ecotone by Pierre‐Yves Mondou Laperrière, Todor S. Minchev, Pierre Grondin, Martin Lavoie, Guillaume de Lafontaine

“…Contemporary dynamics (<200 years) were assessed by analyzing tree size structure of all stems within 400 m2 plots, minimal stand age from tree‐ring dating, as well as the recent occurrence of fire and logging from published ecoforest data. …”
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Elucidating the expression and role of cGAS in pan-cancer using integrated bioinformatics and experimental approaches by Zhen Lian, Xue Liu, Xue Li

“…In this study, The Cancer Genome Atlas (TCGA) and Cancer Cell Line Encyclopedia (CCLE) data were used to analyze the mRNA expression and genomic alterations of cGAS in pan-cancer. …”
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HPV vaccination and Native Americans: protocol for a systematic review of factors associated with HPV vaccine uptake among American Indians and Alaska Natives in the USA by Sameer Vali Gopalani, Ami E Sedani, Amanda E Janitz, Shari C Clifton, Julie Stoner, Jennifer Peck, Ashley Comiford, Alicia L Salvatore, Janis Campbell

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Individualised acute normovolaemic haemodilution for non-cardiac surgery with anticipated high-dose red cell transfusion: study protocol for a randomised controlled trial in West C... by Ren Liao, Jie Zhong, Chenxi Liao, Jinzhe Tan, Jingjing An, Xingning Lai, Leilei Tian

“…Adult patients undergoing elective non-cardiac surgery with an anticipated red cell transfusion volume exceeding eight units (or 1600 mL) will be enrolled and randomly allocated to either the ‘ANH group’ or the ‘Control group’ in a 1:1 ratio. …”
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FEATURES OF INFLUENCE OF EMOTIONAL STRESS DURING PREGNANCY ON THE FORMATION OF EATING BEHAVIOR IN THE CHILD by J. R. Gardanova, S. A. Salehov, V. I. Esaulov, D. F. Khritinin, I. I. Abdullin, S. D. Abdyrahmanov, G. A. Galliamova, K. A. Anisimova

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The drivers of mental health service utilisation among public primary healthcare workers in Negeri Sembilan. by Norhafizah Mohd Noor, Ahmad Azuhairi Ariffin, Halimatus Sakdiah Minhat, Lim Poh Ying, Umi Adzlin Silim

“…Significant drivers predicting MHSU were B40 household income (aOR = 3.426, 95% CI: 1.588, 7.393, p-value = 0.002) and M40 household income (aOR = 3.781, 95% CI: 1.916, 7.460, p-value<0.001), low supervisor support (aOR = 2.302, 95% CI: 1.206, 4.392, p-value = 0.011), received mental health training (aOR = 2.058, 95% CI: 1.221, 3.469, p-value = 0.007) and high co-worker support (aOR = 1.701, 95% CI: 1.034, 2.798, p-value = 0.036).…”
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雷公藤甲素对哮喘小鼠气道重塑及 转化生长因子-β1表达的影响

“…测定支气管管壁厚度(WAt/Pbm),支气管平滑肌厚度(WAm/Pbm)?取右肺组织行RT-PCR检测TGF-β1 mRNA表达。【结果】 B组小鼠支气管管壁厚度、杯状细胞百分数、气道平滑肌厚度、胶原纤维面积、TGF-β1的转录和表达水平均显著高于A组(P < 0.01)。…”
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Guar gum-modified magnetic palladium nanocatalyst: C–N coupling reaction and STAT3-Mediated breast cancer therapy by Junrui Luan, Xin Dong, Shuwen Zhou

“…The Fe3O4@guar gum/Pd NPs showed an IC50 value of 62 μg/mL against MCF-10, respectively. The presence of the material resulted in a 40–50% induction of cell apoptosis, along with down regulation of the anti-apoptotic marker. …”
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Blockade of ICAM-1 Improves the Outcome of Polymicrobial Sepsis via Modulating Neutrophil Migration and Reversing Immunosuppression by Yan-jun Zhao, Wen-jing Yi, Xiao-jian Wan, Jun Wang, Tian-zhu Tao, Jin-bao Li, Jia-feng Wang, Xiao-ming Deng

“…The results demonstrated that ICAM-1 mRNA was upregulated in lung, thymus, and spleen of CLP mice. …”
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Hydrologic response and prediction of future water level changes in Qinghai Lake of Tibet Plateau, China by Haibin Wang, Jiahong Liu, Zhuoran Luo, Sana Nazli, Lu Shi

“…Notably, the QLB has experienced a progressive warming and humidification, leading to expectations of a rise in lake's water level to 3202.64 m by the year 2050. This rise will result in the expansion of the submerged area, primarily concentrated in proximity to the alluvial plains. …”
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Modulation of hormonal, metabolic, inflammatory and oxidative stress biomarkers in women with polycystic ovary syndrome following combined (resistant and endurance) training: a ran... by Masoud Nasiri, Amirabbas Monazzami, Solmaz Alavimilani, Zatollah Asemi

“…Methods This randomized controlled clinical trial was conducted on 30 women with PCOS divided (age: 23.8 ± 5.3 years, height:162.8 ± 4.9 cm, weight: 82.4 ± 9.7 kg, body mass index: 30.3 ± 3.9 kg/m2) into two groups to receive COM training intervention (n = 15) or control group (n = 15) for eight weeks. …”
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Advancements in the Treatment of Mucopolysaccharidoses: From Established Therapies to Gene Therapy by Joanna Wanat, Wojciech Homa, Aleksandra Warunek, Gabriela Gronowicz, Izabela Dzikowska, Agata Siejka, Daria Stefaniak, Weronika Zielińska, Michał Chról

“…Among the promising new treatments are: blood-brain barrier (BBB)-penetrable enzyme replacement therapy (ERT), substrate reduction therapy, nonsense suppression therapy, and mRNA engineering. However, the most advanced treatments, that are currently under investigation are in-vivo and ex-vivo gene therapy. …”
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A high fraction of inspired oxygen does not mitigate atelectasis-induced lung tissue hypoxia or injury in experimental acute respiratory distress syndrome by Kentaro Tojo, Takuya Yazawa

“…All groups were mechanically ventilated with an 8 mL/kg tidal volume and zero end-expiratory pressure to induce dorsal atelectatic regions. …”
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A Novel Liposome Formulation Carrying Both an Insulin Peptide and a Ligand for Invariant Natural Killer T Cells Induces Accumulation of Regulatory T Cells to Islets in Nonobese Dia... by Hidetoshi Akimoto, Emi Fukuda-Kawaguchi, Omar Duramad, Yasuyuki Ishii, Kazunari Tanabe

“…Cotransfer of diabetogenic T cells and splenocytes of NOD mice treated with RGI-3100-iB, but not liposomal α-GalCer encapsulating an unrelated peptide, to NOD-SCID mice resulted in the prevention of diabetes and elevation of Foxp3 mRNA expression in the islets. These data indicate that the migration of insulin B-peptide-specific Tregs to islet of NOD mice that are involved in the suppression of pathogenic T cells related to diabetes onset and progression could be enhanced by the administration of liposomes containing α-GalCer and insulin B peptide.…”
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Gender Difference of the Relationship between Arterial Stiffness and Blood Pressure Variability in Participants in Prehypertension by Yang Lan, Huan Liu, Jinbo Liu, Hongwei Zhao, Hongyu Wang

“…Arterial stiffness (CF-PWV, male versus female, 10.89 ± 2.50 versus 10.33 ± 2.13 m/s, p=0.004) and BPVs (male versus female, 24 h SBPV 13.2 ± 5.11 versus 13.03 ± 5.20; 24 h DBPV 10.34 ± 3.87 versus 9.64 ± 3.59; N SBPV 11.90 ± 6.60 versus 10.94 ± 4.79; N DBPV 9.64 ± 5.87 versus 8.20 ± 4.48, all p<0.05) were higher in male. …”
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Experimental analysis on fiber diameter of spunbond nonwoven fabrics through Plackett–Burman and Box–Behnken designs and its impact on mechanical properties by Kaoutar Abdel‐Mouttalib, Ayoub Nadi, Samir Tetouani, Abdelowahed Hajjaji, Omar Cherkaoui, Samira Touhtouh

“…Our analysis unveiled valuable insights for optimizing process parameters to achieve a target fiber diameter of 31.0 μm, crucial for enhancing nonwoven fabric production. …”
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RISK FACTORS OF LIFE QUALITY REDUCTION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS by Vitalii Dubas

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Analysis of marker substitutions in A/chicken/Astrakhan/2171-1/2020 H5N8 isolate of avian influenza virus recovered in the Astrakhan Oblast by N. G. Zinyakov, A. V. Andriyasov, Ye. V. Ovchinnikova, A. A. Kozlov, P. D. Zhestkov, D. B. Andreychuk, I. A. Chvala

“…The following mutations recognized as pathogenicity determinants in mice were found: 42S in the NS1 protein and 30D protein 215A in M1 protein.…”
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Research on Seepage Properties and Pore Structure of the Roof and Floor Strata in Confined Water-Rich Coal Seams: Taking the Xiaojihan Coal Mine as an Example by Hailong Li

“…Results are as follows: (1) coal seams of Xiaojihan coal mine are confined fractured aquifers, the fissure confined water in coal seams has a strong relationship with total stress-strain permeability and development characteristics of the pore structure of the roof and floor strata. (2) The permeability of the roof and floor strata is extremely low, when the strata is less than 30 meters away from the coal seam with the magnitude order remaining less than 10−12 m/s. If they are closer to the coal seam, the watertightness and plasticity of the strata will be stronger, and the antidestructive capability of the strata during the distortion process will be also increased, resulting in the larger strain for the formation of macroscopic water-conducting fissures. …”
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PSYCHOLOGICAL FEATURES OF PROFESSIONAL IDENTITY CRISIS EXPERIENCE BY TEACHERS by N. O. Sadovnikova, F. Zannoni

“…The following questionnaire methods were used for empirical data collection in the course of the study: the method of biographical reflection of M. V. Klementyeva; differential reflexivity test developed by D. …”
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