Effects of electrolytes on electrochemical behaviour and performance of Ti6Al4V alloy prepared by laser directed energy deposition by Jun Yu, Linzeng Wang, Guoqiang Kang, Xin Lin, Lijun Tian, Pengfei Guo, Liangyi Wu, Weidong Huang

“…The results demonstrate that the NaCl + EDTA-2Na electrolyte attains a moderate EC machining efficiency and the optimal surface roughness of 0.31 μm at its best performance. Transmission electron microscopy reveals distinct dissolution variations between the α and β phases during ECM. …”
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Increased serum soluble PD-l1 levels in patients with advanced stages of chronic kidney disease by Ayaka Hayashi, Ayaka Hayashi, Hiroto Ishihara, Mayuko Kawabe, Kazuhiko Kato, Kazuhiko Kato, Akio Nakashima, Akio Nakashima, Izumi Yamamoto, Teppei Sakano, Teppei Sakano, Hiroe Kobashi, Makoto Morita, Makoto Morita, Takashi Yokoo, Mitsuyoshi Urashima

“…In the Vaccine Cohort, elevated median sPD-L1 levels (pg/mL) were significantly associated with CKD stage progression (P < 0.001), showing exponentially higher levels with CKD progression. …”
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Synergistic regulation and optimization of microstructure, coercivity, and thermal stability in sintered NdFeB magnets through grain boundary diffusion of Dy and Al elements by Rui Chang, Guangzhu Bai, Yaping Li, Zhi Yan, Xiufang Qin, Jingdong Guo, Fang Wang, Xiaohong Xu

“…In this study, we utilize the GBDP method to diffuse low-melting-point DyAl alloy into magnets, resulting in the formation of continuous Dy-, Al-, and Nd-rich thin grain boundary phases and (Nd,Dy)2Fe14B shells with diffusion depths over 1500 μm. These results suggest that the presence of continuous Dy-, Al-, and Nd-rich thin grain boundary phases is crucial in promoting the diffusion of Dy elements in magnets. …”
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Harnessing genetic diversity in cotton for enhanced resilience against salt stress by using agro-physiological characters by Muhammad Mubashar Zafar, Aqsa Ijaz, Zunaira Anwar, Muhammad Shahid Iqbal, Saba Zafar, Mishal Subhan, Mahmoud F. Seleiman, Bushra A. Alhammad, Maha Aljabri, Fei Qiao, Abbas Shoukat, Amir Shakeel, Sezai Ercisli, Arfan Ali, Abdul Razzaq, Xuefei Jiang

“…To evaluate genetic diversity for salt tolerance, 35 diverse cotton accessions were screened under 17 dS m−1 salt stress conditions using 20 agronomic and physiological traits relevant to salt tolerance. …”
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Discovery of Novel Nav1.7-Selective Inhibitors with the 1H-Indole-3-Propionamide Scaffold for Effective Pain Relief by Gaoang Wang, Hang Wu, Yingying Wang, Xiangying Liu, Shuijiao Peng, Wenxing Wang, Meijing Wu, Yifei Liu, Ercheng Wang, Zhe Wang, Lei Xu, Xiaojian Wang, Wei Yang, Haiyi Chen, Xi Zhou, Tingjun Hou

“…Molecular dynamics simulations and experimental findings reveal that the R configuration of WN2 (WN2-R) is the preferred form (IC50 = 24.7 ± 9.4 nM) within the VSDIV pocket of Nav1.7. WN2-R exhibits impressive analgesic effects in acute and chronic inflammatory pain, as well as neuropathic pain models in mice. …”
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CeO2−δ as Electron Donor in Co0.07Ce0.93O2−δ Solid Solution Boosts Alkaline Water Splitting by Gege Su, Yichao Hou, Jie Yin, Jiayi Yang, Zhenglong Li, Xin Du, Xin Zhang, Pinxian Xi, Chun‐Hua Yan

“…The alkaline anion exchange membrane water electrolysis based on Co0.07Ce0.93O2−δ/NiFe LDH realizes a current density of 1000 mA cm−2 at ≈1.86 V in alkaline seawater at 80 °C and exhibits long‐term stability for 450 h.…”
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Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2023 – cohort description, test volumes, predictors of viraemia and the road ahead by Tracy Glass, Frédérique Chammartin, Jochen Ehmer, Thomas Klimkait, Alain Amstutz, Josephine Muhairwe, Irene Ayakaka, Blaise Lukau, Jennifer Anne Brown, Lipontso Motaboli, Malebanye Lerotholi, Maurus Kohler, Kathrin Haenggi, Moliehi Mokete, Makobefo Gladys Chakela, Mpho Kao, Mathebe Kopo, Moleboheng Mokebe, Lorena Urda, Bienvenu Lengo Nsakala, Anna Klicpera, Nadine Tschumi, Niklaus Daniel Labhardt

“…Overall, the proportion of cohort participants with viral suppression to <1000 copies/mL has continually exceeded 90% and has been above 95% since 2020; however, this proportion has consistently been lower among children. …”
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Removal and adsorption kinetics of copper(II) ions from aqueous media on activated carbon in dynamic adsorption on a fixed-bed column by Mve Mfoumou, Charly, Tonda-Mikiéla, Pradel, Ngoye, Francis, Bouassa Mougnala, Spenseur, Mbouiti, Berthy Lionel, Feuya Tchouya, Guy Raymond

“…The best Qsat and E (52.52 mg/g and 55.02%, respectively) were obtained with 0.01 < x < 0.04 mm, D = 2 mL/min, and h = 3 cm, with Cu2+ concentration and pH constant at 250 mg/L and 6.5, respectively. …”
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Feasibility and safety evaluation of ultra-remote robot-assisted laparoscopic hysterectomy by Juyuan Huang, Li'an Li, Jing Cheng, Jing Liao, Yurou Chen, Yi Peng, Sha Wang, Qiongyan Zou, Guoyan Zhao, Wei Zhao, Mengya You, Jingying Yang, Yan Xiong, Kunxian Zhang, Chang Chen, Jiaqiang Xiong, Haotong Guan, Renjie Liu, Peng Zhou, Wuyi Zhao, Yangyang Dong, Xiuli Sun, Sichen Liang, Wei Zhang, Jianliu Wang, Yuanguang Meng

“…The intraoperative blood loss was approximately 20 ​mL, and the surgery lasted about 70 ​min. The bidirectional latency during the operation was around 19 ​ms, with no adverse events related to the robot or the network. …”
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Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer by Tiankai Xu, Chu Chu, Shuyu Xue, Tongchao Jiang, Ying Wang, Wen Xia, Huanxin Lin

“…Results We utilized DMRDEGs to develop a prognostic model that includes four mRNAs for breast cancer. This model combined with various clinical features and critical breast cancer facets, demonstrated remarkable efficacy in predicting patient outcomes. …”
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Topologically constrained DNA-mediated one-pot CRISPR assay for rapid detection of viral RNA with single nucleotide resolutionResearch in context by Yanan Li, Ru Xu, Fenglei Quan, Yonghua Wu, Yige Wu, Yongyuan Zhang, Yan Liang, Zhenzhong Zhang, Hua Gao, Ruijie Deng, Kaixiang Zhang, Jinghong Li

“…Findings: The detection system boasts high sensitivity (0.1 aM), single-base specificity, and the advantage of a rapid “sample-to-answer” process, which takes only 30 min. …”
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Mapping the Distribution and Population Status of <i>Alosa immaculata</i> and <i>Alosa tanaica</i> (Teleostei, Clupeidae) in the Bulgarian Black Sea Area by Desislava Rozdina, Yana Stoyanova, Georgi Terziyski, Slavi Studenkov, Boris Karakushev, Venceslav Delov, Konstantin Mihaylov, Dimitar Kozhuharov, Yordan Kutsarov, Nikolay Kolev, Nikolay Nedyalkov, Nikolay Natchev

“…In the range of a project for mapping the Bulgarian marine protected sites from the network NATURA 2000, we provide an intense investigation of the biology and distribution of both <i>Alosa</i> species. (2) Methods: A trawling survey was carried out within 102 predefined sampling plots of 10 × 10 km grid cells (93 cells on the continental shelf, up to 100 m depth, and 9 offshore cells). In some coastal regions, sampling was conducted with gill nets of different mesh sizes (28 mm to 36 mm). …”
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Factores clínico-epidemiológicos asociados a litiasis residual en pacientes sometidos a litotricia láser by Saul E. Velázquez-Guerrero, Luis A. Gastélum-Félix, Julio A. Ruiz-Torres, Uziel F. Rodríguez-Muñoz, Juan A. Lugo-Machado

“…El índice de masa corporal (IMC) promedio fue de 30,8 ± DS 6,2 kg/m2. Las comorbilidades incluyeron diabetes mellitus en cinco (20,83 %), hipertensión arterial sistémica en ocho (33,00%), obesidad en nueve (37,50 %) y enfermedad renal crónica en dos (8,33 %). …”
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An active shrinkage and antioxidative hydrogel with biomimetic mechanics functions modulates inflammation and fibrosis to promote skin regeneration by Tao Zhang, Xin-Cao Zhong, Zi-Xuan Feng, Xiao-Ying Lin, Chun-Ye Chen, Xiao-Wei Wang, Kai Guo, Yi Wang, Jun Chen, Yong-Zhong Du, Ze-Ming Zhuang, Yong Wang, Wei-Qiang Tan

“…The spatiotemporal release of LMs (ACEI) during the inflammation phase regulated macrophage polarization towards the anti-inflammatory M2 phenotype, promoting progression to the proliferation phase. …”
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A novel USP4 inhibitor that suppresses colorectal cancer stemness by promoting β-catenin and Twist1 degradation by Fengtian Li, Yi Zhou, Xinyue Lin, Yaxin Zhang, Qingyong Hu, Enen Zhao, Huali Li, Xingyan Pan, Feng Shu, Kun Zhang, Chengmei Huang, Na Tang, Wenting Liao

“…Methods RNA sequencing was performed to examine the mRNA expression of known deubiquitinating enzymes in CRC tissues from patients with alternate response to chemotherapy. …”
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IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury by Hongshuang Su, Xiaoxi Lin, Ayinuer Paredong, Ayinuer Paredong, Congcong Yao, Yan Zhang, Mengke Geng, Yuqian Guan, Lichao Gong, Feng Jiang, Qi Lv, Songtao Shou, Heng Jin

“…Inhibition of the IL-6 receptor by tocilizumab in these cells led to a reduction in cellular senescence, accompanied by decreased of the cell cycle regulatory proteins P53 and P21 in mRNA and protein levels, while alleviating cell cycle arrest. …”
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Research Note: Reduction of Salmonella load in Brazilian commercial chicken farms using INSPEKTOR®: a bacteriophage-based product by Michael Pino, Karen Mujica, Paola Mora-Uribe, Héctor Garcias-Papayani, Braulio Paillavil, Camilo Avendaño, Diego Flores-Crisosto, Rodrigo Norambuena, Victoria Rojas-Martínez, Matías Aguilera, Nicolás Cifuentes Muñoz, Pablo Cifuentes, Hans Pieringer, Soledad Ulloa

“…Salmonella load was quantified (DNA copies/mL) by real-time PCR using the invA marker for Salmonella spp., together with serovars Minnesota and Heidelberg, which are relevant to the industry in Brazil. …”
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Assessment of various etiological factors for oral squamous cell carcinoma in non-habit patients- a cross sectional case control study by Mudiyayirakkani Muthusamy, Pratibha Ramani, Paramasivam Arumugam, Parthiban Rudrapathy, Boopathi Kangusamy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman, Balachander Kannan, Anitha Pandi

“…Results Firstly, we found 3 novel pathogenic mutations c.16C > A/p.L6M (missense mutation), c.359 T > C/p.L120P (point mutation), c.382C > T/p.R128W (missense mutation) of HRAS gene in NHOSCC samples by genetic analysis. …”
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Immunosuppressive therapy and nutritional diseases of patients after kidney transplantation: a systematic review by Aleksandra Anna Kajdas, Marcin Kleibert, Anne Katrine Normann, Krzysztof Krasuski, Ditte Søndergaard Linde, Dorota Szostak-Węgierek

“…Finally, mammalian target of rapamycin (mTOR) inhibitors was associated with bone status and mycophenolate mofetil was linked to Vitamin B12 deficiencies. …”
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Telomere Length Is Associated With Adverse Atrial Remodeling in Patients With Atrial Fibrillation by Kabita Pradhan, Balram Neupane, Paul Niehues, Martin Kirschner, Fabian Beier, Chao‐Chung Kuo, Erika Anneliese Hilbold, Christian Bär, Oana‐Maria Thoma, Maximilian Waldner, Margherita Vieri, Tim H. Brümmendorf, Vithurithra Tharmapalan, Wolfgang Wagner, Michael Kleines, Mahdi Emrani, Matthias Daniel Zink, Andreas Napp, Nikolaus Marx, Michael Gramlich

“…TL was quantified and correlated to low voltage areas. 3′ mRNA sequencing was performed for gene expression profiling. …”
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