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48441
Long-term outcome in people who use drugs successfully treated for hepatitis C infection with glecaprevir/pibrentasvir
Published 2024-12-01“…In the GRAND PLAN, we documented sustained virological response post-treatment Week12 (SVR12) in 108/117 (92.3 %) individuals (108/111 (mITT) or 97.3 % of those reaching the SVR12 timepoint) receiving an 8-week course of glecaprevir/pibrentasvir (G/P), with almost all using fentanyl and over half being unstably housed. …”
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48442
Empirical estimation of saturated soil-paste electrical conductivity in the EU using pedotransfer functions and Quantile Regression Forests: A mapping approach based on LUCAS topso...
Published 2025-02-01“…The final model resulted in an R2 of 0.302 with an RMSE of 0.265 dS m−1 for soil samples not used for model calibration. …”
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48443
Assessment approach for conservation effectiveness and gaps for endangered species based on habitat suitability: A case study of alpine musk deer in western China
Published 2025-01-01“…Results indicated that altitude, annual mean temperature, and temperature annual range were the primary environmental factors influencing the distribution of suitable habitats, which were concentrated in areas with altitudes of 3,000–5,000 m, annual mean temperatures of 0–5 °C, and temperature annual ranges of 30–40 °C. …”
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48444
Research on ion cyclotron emission driven by deuterium–deuterium fusion-produced tritium ions on the Experimental Advanced Superconducting Tokamak
Published 2025-01-01“…The excitation position of ICE is approximately R = 2.29 m on EAST, and we find that ICE is easier to excite below a certain threshold of plasma radiation. …”
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48445
Clinicopathological Significance of FOXO4 Expression and Correlation with Prx1 in Head and Neck Squamous Cell Carcinoma
Published 2021-01-01“…By the analysis of Bioinformation Databases, there was a significant interaction of FOXO4 down expression to clinical tumor stages and pathological grades in the patients with HNSCC. Reduced mRNA and protein expression of FOXO4 were found to be significantly correlated with the poor overall survival (OS) of HNSCC patients. …”
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48446
Effects of olive leaf extract on exercise performance and muscle mitochondrial response in young healthy adults
Published 2025-01-01“…Nature Communications, 12(1), 7219. https://doi.org/10.1038/s41467-021-27422-1 Gherardi, C., Rossi, L., Bianchi, M., & Ferri, P. (2024). Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance. …”
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48447
TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders
Published 2024-12-01“…After immunization with Spike/CpG-motifs, mRNA vaccination or SARS-CoV-2 infection, CORSET8 T cells strongly proliferated and showed signs of T cell activation. …”
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48448
Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro
Published 2025-02-01“…Real-time polymerase chain reaction (PCR), Western blot (WB), and immunofluorescence were used to find the expressions of related mRNAs and proteins in the lung tissue or A549 cells. …”
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48449
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48450
Lattice Stabilized and Emission Tunable Pure‐Bromide Quasi‐2D Perovskite for Air‐Processed Blue Light‐Emitting Diodes
Published 2025-02-01“…The champion deep blue PeLED shows maximum external quantum efficiency (EQE) of 2.05% and luminance of 246.56 cd m−2, which are comparable to the state‐of‐the‐art of similar devices fabricated in glovebox. …”
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48451
New Dihydro OO'Bis(Salicylidene) 2,2' Aminobenzothiazolyl Borate Complexes: Kinetic and Voltammetric Studies of Dimethyltin Copper Complex with Guanine, Adenine, and Calf Thymus DN...
Published 2006-01-01“…The kinetic data were obtained from the rate constants, <mml:math alttext="$k_{ m {obs}}$"> <mml:msub> <mml:mi>k</mml:mi> <mml:mrow> <mml:mtext>obs</mml:mtext> </mml:mrow> </mml:msub> </mml:math>, values under pseudo-first-order conditions. …”
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48452
Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat
Published 2025-02-01“…Methods: We investigated entinostat effects on EGFR and amphiregulin (AREG) expression in various cell line- and primary patient tumor-based in vitro, ex vivo and in vivo models, on the mRNA and protein level. Based on these results, a combined entinostat plus EGFR inhibitor erlotinib treatment in vitro and in vivo was studied. …”
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48453
Effects of brown alga, Stoechospermum marginatum extract on growth performance, body chemical compositions and some serum biochemical parameters in grey mullet, Mugil cephalus (Lin...
Published 2023-12-01“…Also, in order to determine the biochemical parameters, blood was taken from the heart using a syringe, and poured into a 2 mL- micro tube. Then, it was centrifuged at 3000 rpm for 10 min and serum was separated and stored at -70°C. …”
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48454
Effects of exogenous selenium application on quality characteristics, selenium speciation, and in vitro bioaccessibility of rice pancakes
Published 2025-01-01“…When sodium selenite was added at 3.3 μg/mL, the maximum values of SeCys2 and MeSeCys were 328.35 ± 33.43 and 311.11 ± 49.48 μg/kg, respectively. …”
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48455
Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity
Published 2022-04-01“…In experiment one, we found that the protein level of Rufy3 decreased and neuronal axon injury in the injured neurons but was rectified by LV-Rufy3 treatment. In experiment two, mRNA and protein levels of Rufy3 were downregulated in brain tissue and reached the lowest level at 24 h after SAH. …”
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48456
Haploinsufficiency of PDE2A causes in mice increased exploratory behavior associated with upregulation of neural nitric oxide synthase in the striatum
Published 2025-02-01“…HET mice exhibited greater tendency to explore novel environments in comparison to WT mice, but spatial working memory, anxiety, and sociability were similar in adult HET and WT mice.In HET mice, PDE2A mRNA, PDE2A protein expression, and cGMP hydrolyzing enzymatic activity were consistently reduced by about 50 %. …”
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48457
Antimicrobial Resistance and Biofilm-Forming Ability in ESBL-Producing and Non-ESBL-Producing <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Isolated from Canine Urinary...
Published 2025-01-01“…Four (11.8%) were ESBL-producing bacteria, all supported by <i>bla</i><sub>CTX-M</sub> gene belonging to group 1. The <i>K. pneumoniae</i> isolates were significantly associated with ESBL production (<i>p</i> < 0.05). …”
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48458
Health and tuberculosis systems resilience, the role of the private sector and pandemic preparedness: insights from a cross-country qualitative study with policy-makers in India, I...
Published 2025-01-01“…Data were analysed thematically using a hybrid inductive-deductive approach, informed by Haldane et al’s Determinants of Health Systems Resilience Framework.Results Policy-makers highlighted the crucial role of intersectoral collaboration, effective governance, innovative financing strategies, health workforce reallocation and technological advancements such as virtual consultations and mHealth in strengthening TB service delivery amid the COVID-19 pandemic. …”
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48459
Associations between Prospective Memory, Executive Function and Physical Activity in Schoolchildren
Published 2025-01-01“…Medicine & Science in Sports & Exercise, 48(6), 1197–1222. https://doi.org/10.1249/MSS.0000000000000901 Loprinzi, P. D., Edwards, M. K., & Frith, E. (2018). Exercise and prospective memory. …”
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48460
A suitability modeling based on geographic information system for potential micro hydropower dam site
Published 2024-01-01“…A total of 635 potential dam locations were identified with high and very high suitability indexes, located on first or second stream orders, within a 4,000 m radius of roads and settlements, outside conservation forest areas, and with a potential hydraulic head greater than 20 meter.CONCLUSION: Integrating a dam suitability index map and restriction factors into a geographic information system framework, enabled a robust analysis for identifying potential sites of micro-hydropower dams. …”
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