Combined therapy of human amnion-derived mesenchymal stem cells and scalp acupuncture alleviates brain damage in a rat model of cerebral palsy by Yu Zhou, Xu-Huan Li, Lu-Na He, Li-Na Wang, Jing Zang, Dong-Ming Wang, Jing Gao, Xue-feng Yu

“…The combination therapy further decreased apoptosis levels, normalized mRNA expression of Bax, Caspase 9, and Caspase 3, and alleviated histological damage. …”
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Triglyceride-glucose index: carotid intima-media thickness and cardiovascular risk in a European population by Chiara Pavanello, Massimiliano Ruscica, Sofia Castiglione, Giuliana Germana Mombelli, Antonia Alberti, Laura Calabresi, Cesare Riccardo Sirtori

“…Participants were generally non-obese, with an average BMI of 24.6 ± 3.5 Kg/m2. Among the women, 83.1% were postmenopausal. …”
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Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis by Fanxuan Zhang, Fang Wang, Lisha Zhao, Leqian Wang, Wenjing Li, Feihua Huang, Feihua Huang, Nani Wang, Nani Wang

“…YNJ-containing serum also decreased the secretion of tumor necrosis factor-α, IL-6, and IL-1β in LPS-stimulated RAW264.7 macrophages, and promoted macrophage polarization toward an M2 phenotype. A total of 23 absorbed components were identified in YNJ-containing serum. …”
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Emergence of Pituitary Adenoma in a Child during Surveillance: Clinical Challenges and the Family Members’ View in an AIP Mutation-Positive Family by Pedro Marques, Sayka Barry, Amy Ronaldson, Arla Ogilvie, Helen L. Storr, Peter J. Goadsby, Michael Powell, Mary N. Dang, Harvinder S. Chahal, Jane Evanson, Ajith V. Kumar, Joan Grieve, Márta Korbonits

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Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning by Tao Zhou, Can Zhu, Wei Zhang, Qiongfang Wu, Mingqiang Deng, Zhiwei Jiang, Longfei Peng, Hao Geng, Zhouting Tuo, Zhouting Tuo, Ci Zou

“…Moreover, PLAC8 overexpression was found to promote the proliferation of urothelial cells without affecting their migratory ability by inhibiting the Akt/mTOR/PI3K signaling pathway.ConclusionsOur study identifies potential diagnostic candidate genes and reveals the complex immune landscape associated with IC/BPS. …”
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Effects of farming specialisation on grassland birds in Mediterranean High Nature Value farmland by Joana Santana, Pedro J. Leitão, Paulo Flores Ribeiro, Pedro Beja, Ângela Lomba, Rui Pedroso, Rui Morgado, Ricardo C. Martins, Inês Catry, Ana Teresa Marques, Luís Reino, Francisco Moreira

“…Pastures were positively related to fallows- and ploughed-related species, M. calandra, Tetrax tetrax, and Galerida larks. …”
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The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion by Maja Reimann, Korkut Avsar, Andrew DiNardo, Torsten Goldmann, Gunar Günther, Michael Hoelscher, Elmira Ibraim, Barbara Kalsdorf, Stefan Kaufmann, Niklas Köhler, Anna Mandalakas, Florian Maurer, Marius Müller, Dörte Nitschkowski, Ioana Olaru, Cristina Popa, Andrea Rachow, Thierry Rolling, Helmut Salzer, Patricia Sanchez-Carballo, Maren Schuhmann, Dagmar Schaub, Victor Spinu, Elena Terhalle, Markus Unnewehr, Nika Zielinski, Jan Heyckendorf, Christoph Lange

“…Conclusion: We identified and validated a whole blood-based RNA signature (TB27) that demonstrates an excellent agreement between predicted and observed times to M. tuberculosis culture conversion during tuberculosis therapy. …”
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TERTp Mutation and its Prognostic Value in Glioma Patients Under the 2021 WHO Classification: A Real‐World Study by Hao Xing, Delin Liu, Junlin Li, Yulu Ge, Xiaopeng Guo, Wenlin Chen, Dachun Zhao, Yixin Shi, Yilin Li, Yaning Wang, Yuekun Wang, Yu Xia, Jiaming Wu, Tingyu Liang, Hai Wang, Qianshu Liu, Shanmu Jin, Tian Qu, Siying Guo, Huanzhang Li, Tianrui Yang, Kun Zhang, Yu Wang, Wenbin Ma

“…Survival analysis showed that TERTp mutation was a predictor of better prognosis in IDH‐mutant grade 2 gliomas (median OS (mOS): not reached (NA) (95% CI: NA–NA) vs. 75.9 (95% CI: 55.4–NA) months, HR = 0.077 (95% CI: 0.01–0.64), p = 0.003), while poor OS was associated with all Grade 4 gliomas (mOS: 17.5 (95% CI: 12.6–24.2) vs. 40.5 (95% CI: 24.4–83.8) months, HR = 2.014 (95% CI: 1.17–3.47), p = 0.01) and all IDH‐wildtype histology grade 2 or 3 gliomas (median OS: 12.6 (95% CI: 11–24.2) vs. 83.8 (95% CI: 35.2–NA) months, HR = 3.768 (95% CI: 1.83–7.78), p < 0.001). …”
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Training Psychological Skills: Efficacy and Assessment of a Nonclinical Psychological Sports Coaching E-Intervention for Young Elite Athletes by Raphaël Bonetti, Fabienne Crettaz von Rotten, Denis Hauw

“…Participants aged 13 to 18 (M = 14.67, SD = 1.13) trained an average of 4.10 times per week (SD = 1.01) and had been practicing their sport for an average of 8.65 years (SD = 2.46). …”
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Within Satisfaction and Distress: Characterizing the First Cultural Transition of Young Talented Cameroonian Footballers by Boris Tachom Waffo, Denis Hauw

“…Holistic perspective on the development of elite athletes. In M. Raab, P. Wylleman, R. Seiler, A.-M. Elbe, & A. …”
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ALMA Observations of Massive Clouds in the Central Molecular Zone: External-pressure-confined Dense Cores and Salpeter-like Core Mass Functions by Zhenying Zhang, Xing Lu, Tie Liu, Sheng-Li Qin, Adam Ginsburg, Yu Cheng, Hauyu Baobab Liu, Daniel L. Walker, Xindi Tang, Shanghuo Li, Qizhou Zhang, Thushara Pillai, Jens Kauffmann, Cara Battersby, Siyi Feng, Suinan Zhang, Qi-Lao Gu, Fengwei Xu, Wenyu Jiao, Xunchuan Liu, Li Chen, Qiu-yi Luo, Xiaofeng Mai, Zi-yang Li, Dongting Yang, Xianjin Shen, Meizhu Liu, Zhiqiang Shen

“…With our new temperature estimates we also find that the CMFs show a Salpeter-like slope in the high-mass (≳3–6 M _⊙ ) end, a change from previous works. Combined with the possible top-heavy initial mass functions (IMFs) in the CMZ, our result suggests that gas accretion and further fragmentation may play important roles in transforming the CMF to the IMF.…”
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Scandinavia in Lithuanian Diplomacy in 1915-1917 by Sandra Grigaravičiūtė

“…The facts in archive documents, old press, memoirs of M. Yčas, J. Tumas Vaižgantas, V. Bartuška, and the Lithuanian historians such as R. …”
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K-Pop Fandom Activism on Social Media: Refuting Accusations of Slacktivism in Internet Activism by Putri Ananda Saka, Zidan Abdul Jabar Saka, Putri Rahmah Nurhakim, Mirna Yusuf, Yuniar Galuh Larasati, Rabiatul Adawiah

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αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke by Yonghuan Yan, Linfang Wu, Lu Wang, Dandan Wang, Mengting Huang, Jinyong Peng, Jinyong Peng, Yingying Huang, Yingying Huang, Yingying Huang

“…However, its mechanism of action remains poorly understood.MethodsThe effects of αAsarone on autophagy were examined by WB, RT-qPCR, immunofluorescence colocalization, transmission electron microscope, and autophagic flux activity was measured by infecting HT22 cells with mRFP-GFP-LC3 adenovirus. And then, cells were transfected with both mimic-miR-499-5p and inhibit-miR-499-5p to investigate the role of miR-499-5p in regulating the effects of αAsarone on stroke. …”
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Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms by Irina Tiganova, Yulia Zhizhimova, Eteri Tolordava, Elena Makarova, Natalia Shevlyagina, Alexander Barmashov, Maria Baryshnikova, Vladimir Zhukhovitsky, Yulia Romanova

“…Results: The absence of dark toxicity of polycationic bacteriochlorins BCl-6 and BCl-7 for human fibroblasts WI-38 at concentrations up to 200 µM and the selectivity of the studied PS to P. aeruginosa 32 bacteria, including these in biofilms, under irradiation, were found. …”
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The institutionalisation of research and innovation in Swiss sports federations – Analysis of the status quo by Cornel Gübeli, Hippolyt Kempf, Solange Emmenegger, Christelle Ganné-Chedeville

“…., Bosshard, B., Mrkonjić, M., Weber, A., Pillet, F., & Sutter, S. (2021). …”
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Porto Alegre Line predicts lenticulostriate arteries encasement and extent of resection in insular gliomas. A preliminary study by Gustavo Rassier Isolan, Gustavo Rassier Isolan, Gustavo Rassier Isolan, Samir Ale Bark, Samir Ale Bark, Jander Moreira Monteiro, Jander Moreira Monteiro, Tobias A. Mattei, Kaan Yağmurlu, Rafaela Fernandes Gonçalves, Rafaela Fernandes Gonçalves, Osvaldo Malafaia, Rafael Roesler, Rafael Roesler, Rafael Roesler, Jurandir Marcondes Ribas Filho

“…In cases with no assumed LSTa involvement, the parameter used to stop resection was the confirmation of the corticospinal tract with 10-mA stimulus. The resection limit of tumors placed medially to the Porto Alegre line was intraoperative direct LSTa visualization.ResultsThe LSTa involvement was the most critical medial limiting factor in more aggressive tumor resection and an excellent overall survival (P = 0.022). …”
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Robotic Surgery from a Gynaecological Oncology Perspective: A Global Gynaecological Oncology Surgical Outcomes Collaborative Led Study (GO SOAR3) by Faiza Gaba, Karen Ash, Oleg Blyuss, Dhivya Chandrasekaran, Marielle Nobbenhuis, Thomas Ind, Elly Brockbank, on behalf of the GO SOAR Collaborators

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Clinical value of soluble urokinase-type plasminogen activator receptor in predicting sepsis-associated acute kidney injury by Wenwen Zhang, Yue Gu, Jing Zhou, Juntao Wang, Xiaoru Zhao, Xiaoyu Deng, Han Li, Lei Yan, Xiaojing Jiao, Fengmin Shao

“…The plasma suPAR had the highest area under the ROC curve of 0.700 (95% confidence interval (CI), 0.621–0.779) at 24-h post-sepsis diagnosis, at which the best discrimination ability for S-AKI was achieved with suPAR of ≥6.31 ng/mL (sensitivity 61.9% and specificity 71.6%). Logistic regression analysis showed that suPAR at 24-h post-sepsis diagnosis remained an independent S-AKI risk factor after adjusting for mechanical ventilation, blood urea nitrogen, and pH.Conclusions The findings suggest that plasma suPAR may be a potential biomarker for early S-AKI diagnosis.…”
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