Use of a wearable device to improve sleep quality by Susan L. Moore, Susan L. Moore, Evan P. Carey, Kristyna Finikiotis, Kelsey L. Ford, Richard D. Zane, Richard D. Zane, Katherine K. Green

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Regenerative fibroblasts derived from autologous skin tissue for the treatment of Sjögren’s syndrome: a case report by Zhao-Xia Ma, Xing-Fei Wu, Li Cao, Cheng-Yan Jiao, Dai-Ping Ma, Yun-Hui Zhao, Zhi-Xing Yang, Min Hu, Min Hu

“…ESR, B lymphocytes, rheumatoid factor IgM, and IgA declined, while the proportion of NK cells increased, and most of the cytokines returned to normal levels. …”
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3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications by Sarvesh Kumar Avinashi, Rajat Kumar Mishra, Shweta, Saurabh Kumar, Amreen Shamsad, Shama Parveen, Surajita Sahu, Savita Kumari, Zaireen Fatima, Sachin Kumar Yadav, Monisha Banerjee, Monalisa Mishra, Neeraj Mehta, Chandki Ram Gautam

“…Moreover, the mechanical study showed excellent compressive strength (188 MPa), a high Young’s modulus (2.84 GPa), and elevated fracture toughness (9.11 MPa.m1/2). An in vitro study by MTT assay on osteoblast (MG-63) cells demonstrated no or minimal cytotoxicity at the higher concentration, 100 µg/ml after 24 h and it was found a more pronounced result at 20 µg/ml on increasing the concentration of Cu nanoparticles after incubating 72 h. …”
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Class III β-Tubulin Overexpression Induces Chemoresistance to Eribulin in a Leiomyosarcoma Cell Line by Kenichiro Yahiro, Yoshihiro Matsumoto, Jun-ichi Fukushi, Ken-ichi Kawaguchi, Makoto Endo, Nokitaka Setsu, Keiichiro IIda, Suguru Fukushima, Makoto Nakagawa, Atsushi Kimura, Yoshinao Oda, Yasuharu Nakashima

“…The IC50 of eribulin was 125 times higher in the resistant cell line than in the parental cell line, and eribulin did not induce G2/M arrest in resistant cells. The resistant cell line showed increased expression of MDR1 transcript, but protein levels and functional analysis results were similar to the parental cell line. …”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…Analysis of the TCGA, GTEx, and UALCAN databases revealed significant differences in NTN1 expression at both the mRNA and protein levels. Prognostic value was evaluated through univariate Cox regression and Kaplan–Meier methods. …”
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Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs by Masaki Shibuya, Masafumi Fujinaka, Mako Yonezawa, Natsumi Nishimura, Hitoshi Uchinoumi, Hiroshi Sunahara, Kenji Tani, Eiji Kobayashi, Motoaki Sano

“…Hydrogen-saturated saline was administered intravenously (125 mL/h) through the left internal jugular vein of pigs, and the blood hydrogen concentration was measured over time. …”
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The role of Akkermansia muciniphila in maintaining health: a bibliometric study by Fangfang Gao, Canyu Cheng, Canyu Cheng, Runwei Li, Zongcun Chen, Zongcun Chen, Ke Tang, Guankui Du, Guankui Du, Guankui Du

“…Among the 820 institutions involved in the research, the University of California (from the United States) and the Chinese Academy of Sciences (from China) occupied central positions. Willem M. De Vos ranked at the top, with 12 publications and 1,108 citations. …”
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The association between age at menarche (AAM) and cardiovascular disease (CVD) risk factors in the MASHAD cohort study by Niloofar Shabani, Sara Saffar Soflaei, Khadijeh Bavafa-Valenlia, Nayereh Esmaeilzadeh, Maryam Mohammadi-Bajgriran, Zahra Namazibaygi, Mohsen Moohebati, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…In girls who menstruated at age ≤ 11 years old, the odds of having a BMI > 28.7 kg/m2, WC > 96 cm, HC > 105 cm and WTR > 61.96 were higher than girls who menstruated at 13 years old. …”
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Engineering of SauriCas9 with enhanced specificity by Xiaoqi Zhang, Chen Tao, Miaomiao Li, Sufang Zhang, Puping Liang, Yan Huang, Huihui Liu, Yongming Wang

“…To validate its efficacy, we employed SauriCas9-R253A to disrupt three genes (B2M, TRAC, and PDCD1), a strategy integral to the development of allogeneic chimeric antigen receptor T cell (CAR-T) therapies. …”
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Clinical comparison and genetic analysis in pheochromocytoma with primary aldosteronism by Xurong Mai, Mitsuhiro Kometani, Toshiaki Kato, Ko Aiga, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Koshiro Nishimoto, Kazuyoshi Hosomichi, Atsushi Watanabe, Yuko Noda, Yoshiyu Takeda, Takashi Yoneda

“…Compared to 15 other patients without primary aldosteronism complications, these three patients had a greater suppression of plasma renin activity (0.2 vs. 2.3 ng/mL/h, p < 0.01) and a higher aldosterone-to-renin ratio (p < 0.01). …”
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MTMR6 downregulation contributes to cisplatin resistance in oral squamous cell carcinoma by Kah Young Lee, Su Young Oh, Heon-Jin Lee, Tae-Geon Kwon, Jin-Wook Kim, Chang-Geol Shin, Su-Hyung Hong, So-Young Choi

“…Mouse xenografts derived from MTMR6-knockdown UMSCC1 cells exhibited increased resistance to cisplatin compared to controls. Conclusion Assessing mRNA levels of MTMR6 and has-miR-544a in biopsy samples could help predict cisplatin responsiveness in OSCC.…”
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Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study) by Lotte Haverman, Eelco Franz, Ka Yin Leung, Albert Jan Van Hoek, Hans Knoop, Cees C van den Wijngaard, Elizabeth N Mutubuki, Tessa van der Maaden, Albert Wong, Anna D Tulen, Siméon de Bruijn

“…Symptom severity will be assessed for fatigue (Checklist Individual Strength (CIS subscale fatigue severity)), pain (Rand-36/SF-36 subscale bodily pain), dyspnoea (Medical Research Council (mMRC)) and cognitive impairment (Cognitive Failure Questionnaire (CFQ)). …”
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Multi-Modal Fusion of Routine Care Electronic Health Records (EHR): A Scoping Review by Zina Ben-Miled, Jacob A. Shebesh, Jing Su, Paul R. Dexter, Randall W. Grout, Malaz A. Boustani

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Wacana Gender Dalam Perjanjian Pernikahan Rifā'ah Rāfi’ Al-Ṭahṭāwī by Rangga Hafidin

“…Perjanjian pernikahan yang bertujuan untuk menghormati seorang istri dibuat oleh Rifā'ah Al-Ṭahṭāwī yang ditujukan kepada istrinya Karima binti Muhammad al-Fargali pada tahun 1839 M. Penelitian ini bertujuan untuk menganalisis bagaimana perempuan ditampilkan dalam perjanjian pernikahan Rifā'ah al-Ṭahṭāwī tersebut. …”
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Lignans from Patrinia scabiosaefolia improve insulin resistance by activating PI-3K/AKT pathway and promoting GLUT4 expression by Zhenhua Liu, Mengke Wang, Lijun Meng, Yixiao Chen, Qiuyi Wang, Yan Zhang, Xuefeng Xi, Wenyi Kang

“…Western blotting experiments showed that compounds 2 and 4 up-regulated the protein expressions of p-IRS, PI-3K, p-AKT and glucose transporter 4 (GLUT4), and promoted the transcription of GLUT4 mRNA. Therefore, the mechanisms of compounds 2 and 4 were presumed to improve IR by activating PI-3K/AKT signaling pathway.…”
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Unleashing the potential of geostationary satellite observations in air quality forecasting through artificial intelligence techniques by C. Zhang, X. Niu, H. Wu, Z. Ding, K. L. Chan, J. Kim, T. Wagner, C. Liu, C. Liu, C. Liu

“…Evaluation against ground-based measurements demonstrates that GeoNet accurately predicts diurnal variations and spatial distribution details of next-day NO<span class="inline-formula">₂</span> pollution, yielding a coefficient of determination of 0.68 and a root mean square of error of 12.31 <span class="inline-formula">µg</span> m<span class="inline-formula">⁻³</span>, significantly surpassing traditional air quality model forecasts. …”
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The SPES3 Experimental Facility Design for the IRIS Reactor Simulation by Mario Carelli, Lawrence Conway, Milorad Dzodzo, Andrea Maioli, Luca Oriani, Gary Storrick, Bojan Petrovic, Andrea Achilli, Gustavo Cattadori, Cinzia Congiu, Roberta Ferri, Marco Ricotti, Davide Papini, Fosco Bianchi, Paride Meloni, Stefano Monti, Fabio Berra, Davor Grgic, Graydon Yoder, Alessandro Alemberti

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 Increasing the resolution of malaria early warning systems for use by local health actors by Michelle V. Evans, Felana A. Ihantamalala, Mauricianot Randriamihaja, Vincent Herbreteau, Christophe Révillion, Thibault Catry, Eric Delaitre, Matthew H. Bonds, Benjamin Roche, Ezra Mitsinjoniala, Fiainamirindra A. Ralaivavikoa, Bénédicte Razafinjato, Oméga Raobela, Andres Garchitorena

“…It combined bias-corrected, village-level case notification data with remotely sensed environmental variables at spatial scales as fine as a 10 m resolution. A spatio-temporal hierarchical generalized linear regression model was trained on monthly malaria case data from 195 communities from 2017 to 2020 and evaluated via cross-validation. …”
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The impact of architectural modifications on relative resistance to fluid flow in ventricular catheters by Rajesh Kumar Madhavan, Ahmad Faryami, Nathan Tappen, Pranav Gopalakrishnan, Shaheer H. Ajaz, Carolyn A. Harris

“…A subset of catheters with varying lumen diameters was tested in 0.30 mL/min saline flow with 2.5% blood to simulate early blood exposure.ResultsWith increasing hole and lumen diameter, we found a significant decrease in overall catheter relative resistance using DIH20 (P &lt; 0.001 and P &lt; 0.002 respectively, n = 5). …”
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Application of fractal model in the Jurassic tight sandstone reservoirs of central Junggar Basin as constrained by mercury ejection curves by Hongkang Zhao, Xiangchun Chang, Tianchen Ge, Zhiping Zeng, Junjian Zhang, Daiqi Ming, Runye Han

“…Type D samples are unique in that they have higher permeability (>0.6 mD) but lower mercury removal efficiency (<35%). …”
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